Zinquin (BioDeep_00000185122)

   

human metabolite blood metabolite


代谢物信息卡片


Ethyl (2-methyl-8-p-toluenesulfonamido-6-quinolyloxy)acetate

化学式: C19H18N2O5S (386.09363780000007)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC1=C2N=C(C)C=CC2=CC(OCC(O)=O)=C1
InChI: InChI=1S/C19H18N2O5S/c1-12-3-7-16(8-4-12)27(24,25)21-17-10-15(26-11-18(22)23)9-14-6-5-13(2)20-19(14)17/h3-10,21H,11H2,1-2H3,(H,22,23)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D064449 - Sequestering Agents > D002614 - Chelating Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

3 个代谢物同义名

Ethyl (2-methyl-8-p-toluenesulfonamido-6-quinolyloxy)acetate; (2-Methyl-8-p-toluenesulfonamido-6-quinolyloxy)acetic acid; Zinquin



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Zahra Khabir, Amy M Holmes, Yi-Jen Lai, Liuen Liang, Anand Deva, Michael A Polikarpov, Michael S Roberts, Andrei V Zvyagin. Human Epidermal Zinc Concentrations after Topical Application of ZnO Nanoparticles in Sunscreens. International journal of molecular sciences. 2021 Nov; 22(22):. doi: 10.3390/ijms222212372. [PMID: 34830253]
  • Mohammad R Karim, David H Petering. Detection of Zn2+ release in nitric oxide treated cells and proteome: dependence on fluorescent sensor and proteomic sulfhydryl groups. Metallomics : integrated biometal science. 2017 04; 9(4):391-401. doi: 10.1039/c6mt00220j. [PMID: 27918051]
  • Andrew B Nowakowski, David H Petering. Reactions of the fluorescent sensor, Zinquin, with the zinc-proteome: adduct formation and ligand substitution. Inorganic chemistry. 2011 Oct; 50(20):10124-33. doi: 10.1021/ic201076w. [PMID: 21905645]
  • Lata Jayaram, Sanjeev Chunilal, Sandy Pickering, Richard E Ruffin, Peter D Zalewski. Sputum zinc concentration and clinical outcome in older asthmatics. Respirology (Carlton, Vic.). 2011 Apr; 16(3):459-66. doi: 10.1111/j.1440-1843.2011.01932.x. [PMID: 21261783]
  • Géraldine Sarret, Emiko Harada, Yong-Eui Choi, Marie-Pierre Isaure, Nicolas Geoffroy, Sirine Fakra, Matthew A Marcus, Mandy Birschwilks, Stephan Clemens, Alain Manceau. Trichomes of tobacco excrete zinc as zinc-substituted calcium carbonate and other zinc-containing compounds. Plant physiology. 2006 Jul; 141(3):1021-34. doi: 10.1104/pp.106.082743. [PMID: 16731580]
  • Anura P Jayasooriya, M Leigh Ackland, Michael L Mathai, Andrew J Sinclair, Harrison S Weisinger, Richard S Weisinger, John E Halver, Klára Kitajka, László G Puskás. Perinatal omega-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood. Proceedings of the National Academy of Sciences of the United States of America. 2005 May; 102(20):7133-8. doi: 10.1073/pnas.0502594102. [PMID: 15883362]
  • Giulia Ranaldi, Giuditta Perozzi, Ai Truong-Tran, Peter Zalewski, Chiara Murgia. Intracellular distribution of labile Zn(II) and zinc transporter expression in kidney and MDCK cells. American journal of physiology. Renal physiology. 2002 Dec; 283(6):F1365-75. doi: 10.1152/ajprenal.00094.2002. [PMID: 12388418]
  • Robert A Colvin. pH dependence and compartmentalization of zinc transported across plasma membrane of rat cortical neurons. American journal of physiology. Cell physiology. 2002 Feb; 282(2):C317-29. doi: 10.1152/ajpcell.00143.2001. [PMID: 11788343]
  • V Snitsarev, T Budde, T P Stricker, J M Cox, D J Krupa, L Geng, A R Kay. Fluorescent detection of Zn(2+)-rich vesicles with Zinquin: mechanism of action in lipid environments. Biophysical journal. 2001 Mar; 80(3):1538-46. doi: 10.1016/s0006-3495(01)76126-7. [PMID: 11222314]
  • N Wellinghausen, M Martin, L Rink. Zinc inhibits interleukin-1-dependent T cell stimulation. European journal of immunology. 1997 Oct; 27(10):2529-35. doi: 10.1002/eji.1830271010. [PMID: 9368606]
  • P D Zalewski, S H Millard, I J Forbes, O Kapaniris, A Slavotinek, W H Betts, A D Ward, S F Lincoln, I Mahadevan. Video image analysis of labile zinc in viable pancreatic islet cells using a specific fluorescent probe for zinc. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 1994 Jul; 42(7):877-84. doi: 10.1177/42.7.8014471. [PMID: 8014471]