Xanthohumol(Random Configuration) (BioDeep_00000185031)
human metabolite blood metabolite natural product
代谢物信息卡片
化学式: C21H22O5 (354.1467)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC(O)=C(CC=C(C)C)C(O)=C1C(=O)C=CC1=CC=C(O)C=C1
InChI: InChI=1S/C21H22O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-9,11-12,22,24-25H,10H2,1-3H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
25 个相关的物种来源信息
- 872542 - Aglaomorpha fortunei: 10.1080/14786410902991860
- 3481 - Cannabaceae: LTS0035219
- 2759 - Eukaryota: LTS0035219
- 9606 - Homo sapiens: -
- 3484 - Humulus: LTS0035219
- 3486 - Humulus lupulus:
- 3486 - Humulus lupulus: 10.1002/IJC.21249
- 3486 - Humulus lupulus: 10.1002/PTR.2286
- 3486 - Humulus lupulus: 10.1002/PTR.2481
- 3486 - Humulus lupulus: 10.1007/S10600-009-9424-9
- 3486 - Humulus lupulus: 10.1016/J.ANTIVIRAL.2004.08.005
- 3486 - Humulus lupulus: 10.1016/S0031-9422(00)97849-X
- 3486 - Humulus lupulus: 10.1016/S0031-9422(96)00744-3
- 3486 - Humulus lupulus: 10.1016/S0278-6915(99)00019-8
- 3486 - Humulus lupulus: 10.1021/JF901244K
- 3486 - Humulus lupulus: 10.1021/NP049783I
- 3486 - Humulus lupulus: 10.1021/NP0499113
- 3486 - Humulus lupulus: 10.1055/S-2005-864154
- 3486 - Humulus lupulus: 10.1248/BPB.26.61
- 3486 - Humulus lupulus: LTS0035219
- 3398 - Magnoliopsida: LTS0035219
- 49840 - Sophora flavescens: 10.1248/YAKUSHI1947.90.4_463
- 35493 - Streptophyta: LTS0035219
- 58023 - Tracheophyta: LTS0035219
- 33090 - Viridiplantae: LTS0035219
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Carmen Pinto, Antonio L Duque, Beatriz Rodríguez-Galdón, Juan J Cestero, Pedro Macías. Xanthohumol prevents carbon tetrachloride-induced acute liver injury in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Oct; 50(10):3405-12. doi:
10.1016/j.fct.2012.07.035
. [PMID: 22884764] - Hanieh Azimi, Ali-Asghar Khakshur, Iman Aghdasi, Mehrnaz Fallah-Tafti, Mohammad Abdollahi. A review of animal and human studies for management of benign prostatic hyperplasia with natural products: perspective of new pharmacological agents.
Inflammation & allergy drug targets.
2012 Jun; 11(3):207-21. doi:
10.2174/187152812800392715
. [PMID: 22512478] - Lucy M Elphick, Nadine Pawolleck, Irina A Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L Harwood, Nick J Plant, Robin S B Williams. Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.
Disease models & mechanisms.
2012 Mar; 5(2):231-40. doi:
10.1242/dmm.008391
. [PMID: 22003123] - LeeCole Legette, Lian Ma, Ralph L Reed, Cristobal L Miranda, John Mark Christensen, Rosita Rodriguez-Proteau, Jan F Stevens. Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
Molecular nutrition & food research.
2012 Mar; 56(3):466-74. doi:
10.1002/mnfr.201100554
. [PMID: 22147307] - Ting-Lin Yen, Chung-King Hsu, Wan-Jung Lu, Cheng-Ying Hsieh, George Hsiao, Duen-Suey Chou, Gong-Jhe Wu, Joen-Rong Sheu. Neuroprotective effects of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), in ischemic stroke of rats.
Journal of agricultural and food chemistry.
2012 Feb; 60(8):1937-44. doi:
10.1021/jf204909p
. [PMID: 22300539] - Jaroslav Matoušek, Tomáš Kocábek, Josef Patzak, Zoltán Füssy, Jitka Procházková, Arne Heyerick. Combinatorial analysis of lupulin gland transcription factors from R2R3Myb, bHLH and WDR families indicates a complex regulation of chs_H1 genes essential for prenylflavonoid biosynthesis in hop (Humulus Lupulus L.).
BMC plant biology.
2012 Feb; 12(?):27. doi:
10.1186/1471-2229-12-27
. [PMID: 22340661] - Y Wang, Y Chen, J Wang, J Chen, B B Aggarwal, X Pang, M Liu. Xanthohumol, a prenylated chalcone derived from hops, suppresses cancer cell invasion through inhibiting the expression of CXCR4 chemokine receptor.
Current molecular medicine.
2012 Feb; 12(2):153-62. doi:
10.2174/156652412798889072
. [PMID: 22172099] - Yusuke Tsurumaru, Kanako Sasaki, Tatsuya Miyawaki, Yoshihiro Uto, Takayuki Momma, Naoyuki Umemoto, Masaki Momose, Kazufumi Yazaki. HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops.
Biochemical and biophysical research communications.
2012 Jan; 417(1):393-8. doi:
10.1016/j.bbrc.2011.11.125
. [PMID: 22166201] - Mi-Yeon Cho, Su-Young Park, Sumin Park, Yong Rok Lee, Gi-Dong Han, Jung-Ae Kim. Geranyl derivative of phloroacetophenone induces cancer cell-specific apoptosis through Bax-mediated mitochondrial pathway in MCF-7 human breast cancer cells.
Biological & pharmaceutical bulletin.
2012; 35(1):98-104. doi:
10.1248/bpb.35.98
. [PMID: 22223344] - Gabriele Multhoff, Jürgen Radons. Radiation, inflammation, and immune responses in cancer.
Frontiers in oncology.
2012; 2(?):58. doi:
10.3389/fonc.2012.00058
. [PMID: 22675673] - A Gatica-Arias, M A Farag, M Stanke, J Matoušek, L Wessjohann, G Weber. Flavonoid production in transgenic hop (Humulus lupulus L.) altered by PAP1/MYB75 from Arabidopsis thaliana L.
Plant cell reports.
2012 Jan; 31(1):111-9. doi:
10.1007/s00299-011-1144-5
. [PMID: 21912858] - Rita Negrão, Raquel Costa, Delfim Duarte, Tiago Taveira Gomes, Pedro Coelho, João T Guimarães, Luísa Guardão, Isabel Azevedo, Raquel Soares. Xanthohumol-supplemented beer modulates angiogenesis and inflammation in a skin wound healing model. Involvement of local adipocytes.
Journal of cellular biochemistry.
2012 Jan; 113(1):100-9. doi:
10.1002/jcb.23332
. [PMID: 21898537] - Ye-Ming Lee, Kuo-Hsien Hsieh, Wan-Jung Lu, Hsiu-Chu Chou, Duen-Suey Chou, Li-Ming Lien, Joen-Rong Sheu, Kuan-Hung Lin. Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), Prevents Platelet Activation in Human Platelets.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):852362. doi:
10.1155/2012/852362
. [PMID: 22611436] - L P Hemachandra, P Madhubhani, R Chandrasena, P Esala, Shao-Nong Chen, Matthew Main, David C Lankin, Robert A Scism, Birgit M Dietz, Guido F Pauli, Gregory R J Thatcher, Judy L Bolton. Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A).
Cancer prevention research (Philadelphia, Pa.).
2012 Jan; 5(1):73-81. doi:
10.1158/1940-6207.capr-11-0348
. [PMID: 21997247] - Kent Sakai, Nobuhiro Koyama, Takashi Fukuda, Yukiko Mori, Hiroyasu Onaka, Hiroshi Tomoda. Search method for inhibitors of Staphyloxanthin production by methicillin-resistant Staphylococcus aureus.
Biological & pharmaceutical bulletin.
2012; 35(1):48-53. doi:
10.1248/bpb.35.48
. [PMID: 22223336] - Ulrike Grienke, Judit Mihály-Bison, Daniela Schuster, Taras Afonyushkin, Markus Binder, Shu-hong Guan, Chun-ru Cheng, Gerhard Wolber, Hermann Stuppner, De-an Guo, Valery N Bochkov, Judith M Rollinger. Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum.
Bioorganic & medicinal chemistry.
2011 Nov; 19(22):6779-91. doi:
10.1016/j.bmc.2011.09.039
. [PMID: 22014750] - Wieland Peschel, Alfred Kump, José Maria Prieto. Effects of 20-hydroxyecdysone, Leuzea carthamoides extracts, dexamethasone and their combinations on the NF-κB activation in HeLa cells.
The Journal of pharmacy and pharmacology.
2011 Nov; 63(11):1483-95. doi:
10.1111/j.2042-7158.2011.01349.x
. [PMID: 21988429] - Manuela M Moreira, Ana M Carvalho, Ines M Valente, Luis M Goncalves, Jose A Rodrigues, Aquiles A Barros, Luis F Guido. Novel application of square-wave adsorptive-stripping voltammetry for the determination of xanthohumol in spent hops.
Journal of agricultural and food chemistry.
2011 Jul; 59(14):7654-8. doi:
10.1021/jf2011485
. [PMID: 21671607] - Hyung Min Jeong, Eun Hee Han, Yun Hye Jin, You Hee Choi, Kwang Youl Lee, Hye Gwang Jeong. Xanthohumol from the hop plant stimulates osteoblast differentiation by RUNX2 activation.
Biochemical and biophysical research communications.
2011 May; 409(1):82-9. doi:
10.1016/j.bbrc.2011.04.113
. [PMID: 21565172] - Dennis Stracke, Tobias Schulz, Peter Prehm. Inhibitors of hyaluronan export from hops prevent osteoarthritic reactions.
Molecular nutrition & food research.
2011 Mar; 55(3):485-94. doi:
10.1002/mnfr.201000210
. [PMID: 20848398] - Yun-Jan Wang, Jinhui Dou, Kevin P Cross, Luis G Valerio. Computational analysis for hepatic safety signals of constituents present in botanical extracts widely used by women in the United States for treatment of menopausal symptoms.
Regulatory toxicology and pharmacology : RTP.
2011 Feb; 59(1):111-24. doi:
10.1016/j.yrtph.2010.09.012
. [PMID: 20920542] - Enzo A Palombo. Traditional Medicinal Plant Extracts and Natural Products with Activity against Oral Bacteria: Potential Application in the Prevention and Treatment of Oral Diseases.
Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):680354. doi:
10.1093/ecam/nep067
. [PMID: 19596745] - Rita Negrão, Raquel Costa, Delfim Duarte, Tiago Taveira Gomes, Mário Mendanha, Liane Moura, Luísa Vasques, Isabel Azevedo, Raquel Soares. Angiogenesis and inflammation signaling are targets of beer polyphenols on vascular cells.
Journal of cellular biochemistry.
2010 Dec; 111(5):1270-9. doi:
10.1002/jcb.22850
. [PMID: 20803553] - Laura Hanske, Gunnar Loh, Silke Sczesny, Michael Blaut, Annett Braune. Recovery and metabolism of xanthohumol in germ-free and human microbiota-associated rats.
Molecular nutrition & food research.
2010 Oct; 54(10):1405-13. doi:
10.1002/mnfr.200900517
. [PMID: 20397197] - Isvett J Flores-Sanchez, Huub J M Linthorst, Robert Verpoorte. In silicio expression analysis of PKS genes isolated from Cannabis sativa L.
Genetics and molecular biology.
2010 Oct; 33(4):703-13. doi:
10.1590/s1415-47572010005000088
. [PMID: 21637580] - D Deeb, X Gao, H Jiang, A S Arbab, S A Dulchavsky, S C Gautam. Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells.
Anticancer research.
2010 Sep; 30(9):3333-9. doi:
. [PMID: 20944105]
- Christoph Dorn, Birgit Kraus, Magdalena Motyl, Thomas S Weiss, Manfred Gehrig, Jürgen Schölmerich, Jörg Heilmann, Claus Hellerbrand. Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis.
Molecular nutrition & food research.
2010 Jul; 54 Suppl 2(?):S205-13. doi:
10.1002/mnfr.200900314
. [PMID: 20087858] - Christoph Dorn, Frauke Bataille, Erwin Gaebele, Jörg Heilmann, Claus Hellerbrand. Xanthohumol feeding does not impair organ function and homoeostasis in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2010 Jul; 48(7):1890-7. doi:
10.1016/j.fct.2010.04.030
. [PMID: 20427021] - Anthony L Schilmiller, Dennis P Miner, Matthew Larson, Eric McDowell, David R Gang, Curtis Wilkerson, Robert L Last. Studies of a biochemical factory: tomato trichome deep expressed sequence tag sequencing and proteomics.
Plant physiology.
2010 Jul; 153(3):1212-23. doi:
10.1104/pp.110.157214
. [PMID: 20431087] - Robert Jirásko, Michal Holcapek, Eva Vrublová, Jitka Ulrichová, Vilím Simánek. Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry.
Journal of chromatography. A.
2010 Jun; 1217(25):4100-8. doi:
10.1016/j.chroma.2010.02.041
. [PMID: 20227705] - Paulo J Magalhães, Joana S Vieira, Luís M Gonçalves, João G Pacheco, Luís F Guido, Aquiles A Barros. Isolation of phenolic compounds from hop extracts using polyvinylpolypyrrolidone: characterization by high-performance liquid chromatography-diode array detection-electrospray tandem mass spectrometry.
Journal of chromatography. A.
2010 May; 1217(19):3258-68. doi:
10.1016/j.chroma.2009.10.068
. [PMID: 19913228] - Ciska Wyns, Selin Bolca, Denis De Keukeleire, Arne Heyerick. Development of a high-throughput LC/APCI-MS method for the determination of thirteen phytoestrogens including gut microbial metabolites in human urine and serum.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Apr; 878(13-14):949-56. doi:
10.1016/j.jchromb.2010.02.022
. [PMID: 20299290] - Ni Zhang, Zhengwen Liu, Qunying Han, Jinghong Chen, Yi Lv. Xanthohumol enhances antiviral effect of interferon alpha-2b against bovine viral diarrhea virus, a surrogate of hepatitis C virus.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2010 Apr; 17(5):310-6. doi:
10.1016/j.phymed.2009.08.005
. [PMID: 19748253] - Dieter Treutter. Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints.
International journal of molecular sciences.
2010 Mar; 11(3):807-57. doi:
10.3390/ijms11030807
. [PMID: 20479987] - Neena Philips, Mathew Samuel, Rosemarie Arena, Yu-Jun Chen, Jennifer Conte, Prashanthi Natarajan, Prashanti Natrajan, Gerhard Haas, Salvador Gonzalez. Direct inhibition of elastase and matrixmetalloproteinases and stimulation of biosynthesis of fibrillar collagens, elastin, and fibrillins by xanthohumol.
Journal of cosmetic science.
2010 Mar; 61(2):125-32. doi:
"
. [PMID: 20447364] - Ana M Fortes, Filipa Santos, Maria S Pais. Organogenic nodule formation in hop: a tool to study morphogenesis in plants with biotechnological and medicinal applications.
Journal of biomedicine & biotechnology.
2010; 2010(?):. doi:
10.1155/2010/583691
. [PMID: 20811599] - Andreas Hartkorn, Florian Hoffmann, Hussam Ajamieh, Susanne Vogel, Jörg Heilmann, Alexander L Gerbes, Angelika M Vollmar, Stefan Zahler. Antioxidant effects of xanthohumol and functional impact on hepatic ischemia-reperfusion injury.
Journal of natural products.
2009 Oct; 72(10):1741-7. doi:
10.1021/np900230p
. [PMID: 19757857] - Elvira Lupinacci, Jocelijn Meijerink, Jean-Paul Vincken, Bartolo Gabriele, Harry Gruppen, Renger F Witkamp. Xanthohumol from hop (Humulus lupulus L.) is an efficient inhibitor of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha release in LPS-stimulated RAW 264.7 mouse macrophages and U937 human monocytes.
Journal of agricultural and food chemistry.
2009 Aug; 57(16):7274-81. doi:
10.1021/jf901244k
. [PMID: 19634869] - Srujana Rayalam, Jeong-Yeh Yang, Mary Anne Della-Fera, Hea Jin Park, Suresh Ambati, Clifton A Baile. Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes.
Journal of medicinal food.
2009 Aug; 12(4):846-53. doi:
10.1089/jmf.2008.0158
. [PMID: 19735186] - Flávia C M Lopes, Ana Rocha, Ana Pirraco, Luis O Regasini, Dulce H S Silva, Vanderlan S Bolzani, Isabel Azevedo, Iracilda Z Carlos, Raquel Soares. Anti-angiogenic effects of pterogynidine alkaloid isolated from Alchornea glandulosa.
BMC complementary and alternative medicine.
2009 May; 9(?):15. doi:
10.1186/1472-6882-9-15
. [PMID: 19463163] - Paulo J Magalhães, Daniel O Carvalho, José M Cruz, Luís F Guido, Aquiles A Barros. Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer.
Natural product communications.
2009 May; 4(5):591-610. doi:
"
. [PMID: 19445313] - Naoto Yamaguchi, Keiko Satoh-Yamaguchi, Mitsunori Ono. In vitro evaluation of antibacterial, anticollagenase, and antioxidant activities of hop components (Humulus lupulus) addressing acne vulgaris.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2009 Apr; 16(4):369-76. doi:
10.1016/j.phymed.2008.12.021
. [PMID: 19201179] - Ava Jiangyang Guo, Roy Chi-yan Choi, Anna Wing-han Cheung, Jun Li, Ivy Xiaoying Chen, Tina Tingxia Dong, Karl Wah-keung Tsim, Brad Wing-chuen Lau. Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines.
Chinese medicine.
2009 Mar; 4(?):5. doi:
10.1186/1749-8546-4-5
. [PMID: 19321011] - Kuzhuvelil B Harikumar, Ajaikumar B Kunnumakkara, Kwang S Ahn, Preetha Anand, Sunil Krishnan, Sushovan Guha, Bharat B Aggarwal. Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells.
Blood.
2009 02; 113(9):2003-13. doi:
10.1182/blood-2008-04-151944
. [PMID: 18952893] - Mohammad Al-Mamun, Kunio Goto, Sota Chiba, Hiroaki Sano. Responses of plasma acetate metabolism to hop (Humulus lupulus L.) in sheep.
International journal of biological sciences.
2009; 5(3):287-92. doi:
10.7150/ijbs.5.287
. [PMID: 19365576] - M David Marks, Li Tian, Jonathan P Wenger, Stephanie N Omburo, Wilfredo Soto-Fuentes, Ji He, David R Gang, George D Weiblen, Richard A Dixon. Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa.
Journal of experimental botany.
2009; 60(13):3715-26. doi:
10.1093/jxb/erp210
. [PMID: 19581347] - Vanda Mendes, Rosário Monteiro, Diogo Pestana, Diana Teixeira, Conceição Calhau, Isabel Azevedo. Xanthohumol influences preadipocyte differentiation: implication of antiproliferative and apoptotic effects.
Journal of agricultural and food chemistry.
2008 Dec; 56(24):11631-7. doi:
10.1021/jf802233q
. [PMID: 19035642] - Yi-Chien Ho, Chi-Hsien Liu, Chien-Nan Chen, Kow-Jen Duan, Ming-Tse Lin. Inhibitory effects of xanthohumol from hops (Humulus lupulus L.) on human hepatocellular carcinoma cell lines.
Phytotherapy research : PTR.
2008 Nov; 22(11):1465-8. doi:
10.1002/ptr.2481
. [PMID: 18814205] - Jeung-Hyun Koo, Hyoung Tae Kim, Ha-Yong Yoon, Kang-Beom Kwon, Il-Whan Choi, Sung Hoo Jung, Han-Uk Kim, Byung-Hyun Park, Jin-Woo Park. Effect of xanthohumol on melanogenesis in B16 melanoma cells.
Experimental & molecular medicine.
2008 Jun; 40(3):313-9. doi:
10.3858/emm.2008.40.3.313
. [PMID: 18587269] - Paola Zanoli, Manuela Zavatti. Pharmacognostic and pharmacological profile of Humulus lupulus L.
Journal of ethnopharmacology.
2008 Mar; 116(3):383-96. doi:
10.1016/j.jep.2008.01.011
. [PMID: 18308492] - Janja Plazar, Metka Filipic, Geny M M Groothuis. Antigenotoxic effect of Xanthohumol in rat liver slices.
Toxicology in vitro : an international journal published in association with BIBRA.
2008 Mar; 22(2):318-27. doi:
10.1016/j.tiv.2007.09.009
. [PMID: 17981005] - P Natarajan, S Katta, I Andrei, V Babu Rao Ambati, M Leonida, G J Haas. Positive antibacterial co-action between hop (Humulus lupulus) constituents and selected antibiotics.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2008 Mar; 15(3):194-201. doi:
10.1016/j.phymed.2007.10.008
. [PMID: 18162387] - Javor Kac, Janja Plazar, Ales Mlinaric, Bojana Zegura, Tamara T Lah, Metka Filipic. Antimutagenicity of hops (Humulus lupulus L.): bioassay-directed fractionation and isolation of xanthohumol.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2008 Mar; 15(3):216-20. doi:
10.1016/j.phymed.2007.09.008
. [PMID: 17959367] - L Delmulle, T Vanden Berghe, D De Keukeleire, P Vandenabeele. Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death.
Phytotherapy research : PTR.
2008 Feb; 22(2):197-203. doi:
10.1002/ptr.2286
. [PMID: 17726738] - M E Bracke, B W A Vanhoecke, L Derycke, S Bolca, S Possemiers, A Heyerick, C V Stevens, D De Keukeleire, H T Depypere, W Verstraete, C A Williams, S T McKenna, S Tomar, D Sharma, A K Prasad, A L DePass, V S Parmar. Plant polyphenolics as anti-invasive cancer agents.
Anti-cancer agents in medicinal chemistry.
2008 Feb; 8(2):171-85. doi:
10.2174/187152008783497037
. [PMID: 18288920] - Jana Nagel, Lana K Culley, Yuping Lu, Enwu Liu, Paul D Matthews, Jan F Stevens, Jonathan E Page. EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol.
The Plant cell.
2008 Jan; 20(1):186-200. doi:
10.1105/tpc.107.055178
. [PMID: 18223037] - Jeong-Yeh Yang, Mary Anne Della-Fera, Srujana Rayalam, Clifton A Baile. Effect of xanthohumol and isoxanthohumol on 3T3-L1 cell apoptosis and adipogenesis.
Apoptosis : an international journal on programmed cell death.
2007 Nov; 12(11):1953-63. doi:
10.1007/s10495-007-0130-4
. [PMID: 17874298] - Selin Bolca, Sam Possemiers, Veerle Maervoet, Inge Huybrechts, Arne Heyerick, Stefaan Vervarcke, Herman Depypere, Denis De Keukeleire, Marc Bracke, Stefaan De Henauw, Willy Verstraete, Tom Van de Wiele. Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women.
The British journal of nutrition.
2007 Nov; 98(5):950-9. doi:
10.1017/s0007114507749243
. [PMID: 17521469] - Lei Zhang, Liang Xu, Shan-Shan Xiao, Qiong-Feng Liao, Qing Li, Jian Liang, Xiao-Hui Chen, Kai-Shun Bi. Characterization of flavonoids in the extract of Sophora flavescens Ait. by high-performance liquid chromatography coupled with diode-array detector and electrospray ionization mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2007 Sep; 44(5):1019-28. doi:
10.1016/j.jpba.2007.04.019
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Cancer letters.
2007 Feb; 246(1-2):201-9. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
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International journal of cancer.
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Biochemical and biophysical research communications.
2005 Oct; 336(3):754-61. doi:
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Molecular nutrition & food research.
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Molecular nutrition & food research.
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The Journal of steroid biochemistry and molecular biology.
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Molecular nutrition & food research.
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Molecular nutrition & food research.
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Journal of agricultural and food chemistry.
2005 Aug; 53(16):6281-8. doi:
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Chemical research in toxicology.
2005 Aug; 18(8):1296-305. doi:
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Journal of agricultural and food chemistry.
2005 Jun; 53(12):4793-8. doi:
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Archives of pharmacal research.
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Journal of agricultural and food chemistry.
2005 Apr; 53(8):2881-9. doi:
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Cancer letters.
2005 Mar; 219(2):215-22. doi:
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Journal of mass spectrometry : JMS.
2005 Mar; 40(3):289-99. doi:
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In vivo (Athens, Greece).
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Antiviral research.
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Journal of chromatographic science.
2004 Aug; 42(7):378-82. doi:
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Phytochemistry.
2004 May; 65(10):1317-30. doi:
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Phytochemistry.
2004 Mar; 65(5):561-70. doi:
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Antiviral research.
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Chemical research in toxicology.
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Journal of agricultural and food chemistry.
2003 Jul; 51(15):4436-41. doi:
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Biological & pharmaceutical bulletin.
2003 Jan; 26(1):61-5. doi:
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Molecular cancer therapeutics.
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2001 Dec; 39(12):1211-24. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2001 May; 39(5):437-45. doi:
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