Benzo(a)naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-8,13-dioxo-3-(2-hydroxypropyl)-7-methoxy-1,6,9,14-tetrahydroxy- (BioDeep_00000185022)
human metabolite blood metabolite
代谢物信息卡片
化学式: C27H22O10 (506.1212912)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 75%
分子结构信息
SMILES: CC(CC1=C(C(=C2C(=C1)CC(C3=C2C(=C4C(=C3OC)C(=O)C5=C(C4=O)C=CC=C5O)O)O)O)C(=O)O)O
InChI: InChI=1S/C27H22O10/c1-9(28)6-10-7-11-8-14(30)18-19(15(11)23(32)16(10)27(35)36)25(34)20-21(26(18)37-2)24(33)17-12(22(20)31)4-3-5-13(17)29/h3-5,7,9,14,28-30,32,34H,6,8H2,1-2H3,(H,35,36)
描述信息
同义名列表
3 个代谢物同义名
2,5,11,17-tetrahydroxy-7-(2-hydroxypropyl)-13-methoxy-15,22-dioxopentacyclo[12.8.0.0³,¹².0⁴,⁹.0¹⁶,²¹]docosa-1(14),2,4,6,8,12,16,18,20-nonaene-6-carboxylic acid; Sodium 1,6,9,14-tetrahydroxy-3-(2-hydroxypropyl)-7-methoxy-8,13-dioxo-5,6,8,13-tetrahydrobenzo(a)naphthacene-2-carboxylate; Benzo(a)naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-8,13-dioxo-3-(2-hydroxypropyl)-7-methoxy-1,6,9,14-tetrahydroxy-
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fuchao Xu, Yonghong Liang, Jie Ren, Siyuan Wang, Jixun Zhan. Discovery of a novel analogue of FR901533 and the corresponding biosynthetic gene cluster from Streptosporangium roseum No. 79089.
Applied microbiology and biotechnology.
2020 Aug; 104(16):7131-7142. doi:
10.1007/s00253-020-10765-y. [PMID: 32632478] - Atsuyuki Wada, Masato Ohnishi, Takayoshi Tsutamoto, Masanori Fujii, Takehiro Matsumoto, Takashi Yamamoto, Xinwen Wang, Masahiko Kinoshita. Chronic effects of an endothelin-converting enzyme inhibitor on cardiorenal and hormonal function in heart failure.
Clinical science (London, England : 1979).
2002 Aug; 103 Suppl 48(?):254S-257S. doi:
10.1042/cs103s254s. [PMID: 12193098] - X Wang, M Ohnishi, A Wada, T Tsutamoto, M Sawaki, M Fujii, T Matsumoto, T Yamamoto, K Kurokawa, H Yamada, M Kinoshita. Endothelin-1 promotes vascular structural remodeling during the progression of heart failure prevention of vascular remodeling using a specific endothelin-converting enzyme inhibitor.
Life sciences.
2001 Oct; 69(21):2477-88. doi:
10.1016/s0024-3205(01)01333-9. [PMID: 11693256] - A Ergul, A L Grubbs, Y Zhang, F G Spinale. Selective upregulation of endothelin converting enzyme-1a in the human failing heart.
Journal of cardiac failure.
2000 Dec; 6(4):314-20. doi:
10.1054/jcaf.2000.19227. [PMID: 11145756] - P Martin, A Tzanidis, A Stein-Oakley, H Krum. Effect of a highly selective endothelin-converting enzyme inhibitor on cardiac remodeling in rats after myocardial infarction.
Journal of cardiovascular pharmacology.
2000 Nov; 36(5 Suppl 1):S367-70. doi:
10.1097/00005344-200036051-00106. [PMID: 11078422] - A Wada, T Tsutamoto, M Ohnishi, M Sawaki, D Fukai, Y Maeda, M Kinoshita. Effects of a specific endothelin-converting enzyme inhibitor on cardiac, renal, and neurohumoral functions in congestive heart failure: comparison of effects with those of endothelin A receptor antagonism.
Circulation.
1999 Feb; 99(4):570-7. doi:
10.1161/01.cir.99.4.570. [PMID: 9927406] - T Takahashi, T Kanda, M Inoue, H Sumino, I Kobayashi, A Iwamoto, R Nagai. Endothelin converting enzyme inhibitor protects development of right ventricular overload and medial thickening of pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
Life sciences.
1998; 63(10):PL137-43. doi:
10.1016/s0024-3205(98)00347-6. [PMID: 9734710]