vibunazole (BioDeep_00000184942)
human metabolite blood metabolite
代谢物信息卡片
化学式: C15H20ClN3O2 (309.124397)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)C(CN1C=NC=N1)(COC2=CC=C(C=C2)Cl)O
InChI: InChI=1S/C15H20ClN3O2/c1-14(2,3)15(20,8-19-11-17-10-18-19)9-21-13-6-4-12(16)5-7-13/h4-7,10-11,20H,8-9H2,1-3H3
描述信息
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- PubChem: 123676
- HMDB: HMDB0259802
- ChEMBL: CHEMBL4757643
- chemspider: 110253
- CAS: 104358-26-1
- CAS: 104358-25-0
- CAS: 80456-55-9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- G K Abruzzo, D M Giltinan, T P Capizzi, R A Fromtling. Influence of six antifungal agents on the chemiluminescence response of mouse spleen cells.
Antimicrobial agents and chemotherapy.
1986 Apr; 29(4):602-7. doi:
10.1128/aac.29.4.602. [PMID: 3707108] - F Meunier. Serum fungistatic and fungicidal activity in volunteers receiving antifungal agents.
European journal of clinical microbiology.
1986 Feb; 5(1):103-9. doi:
10.1007/bf02013478. [PMID: 3516681] - C van Gulpen, O Kelder, H Mattie, J W van der Meer, J van't Wout. Pharmacokinetics of vibunazole (BAY n 7133) administered orally to healthy subjects.
The Journal of antimicrobial chemotherapy.
1985 Jul; 16(1):75-9. doi:
10.1093/jac/16.1.75. [PMID: 4044466] - J R Perfect, D T Durack. Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits.
The Journal of antimicrobial chemotherapy.
1985 Jul; 16(1):81-6. doi:
10.1093/jac/16.1.81. [PMID: 2995303] - H Ackerbauer, J G Meingassner, H Mieth. [Experimental renal infection with Aspergillus fumigatus in mice: a chemotherapeutic model of an organic mycosis].
Mykosen.
1985 May; 28(5):244-50. doi:
10.1111/j.1439-0507.1985.tb02124.x. [PMID: 2989682] - E Lefler, D A Stevens. New azole compounds: vibunazole (Bay n7133) and Bay L9139, compared with ketoconazole in the therapy of systemic candidosis and in pharmacokinetic studies, in mice.
The Journal of antimicrobial chemotherapy.
1985 Jan; 15(1):69-75. doi:
10.1093/jac/15.1.69. [PMID: 3972759] - W Ritter, M Plempel. Pharmacokinetics of the oral triazole antimycotic vibunazole in animals.
The Journal of antimicrobial chemotherapy.
1984 Sep; 14(3):243-52. doi:
10.1093/jac/14.3.243. [PMID: 6490569] - C E Fasching, C E Hughes, R F Hector, L R Peterson. High-pressure liquid chromatographic assay of Bay n 7133 in human serum.
Antimicrobial agents and chemotherapy.
1984 May; 25(5):596-8. doi:
10.1128/aac.25.5.596. [PMID: 6375561] - H B Levine. A direct comparison of oral treatments with BAY-n-7133, BAY-1-9139 and ketoconazole in experimental murine coccidioidomycosis.
Sabouraudia.
1984; 22(1):37-46. doi:
10.1080/00362178485380071. [PMID: 6322362] - H T Versmold, C Linderkamp, C Döhlemann, K P Riegel. Oxygen transport in congenital heart disease: influence of fetal hemoglobin, red cell pH, and 2,3-diphosphoglycerate.
Pediatric research.
1976 Jun; 10(6):566-70. doi:
10.1203/00006450-197606000-00002. [PMID: 5699] - N N Aronson, A Yannarell. Effects of membrane ribonuclease and 3'-nucleotidase on the digestion of polyuridylic acid by rat liver plasma membrane.
Biochimica et biophysica acta.
1975 Nov; 413(1):135-42. doi:
10.1016/0005-2736(75)90064-4. [PMID: 89] - P E Phillips. The virus hypothesis in systemic lupus erythematosus.
Annals of internal medicine.
1975 Nov; 83(5):709-15. doi:
10.7326/0003-4819-83-5-709. [PMID: 938]