1,1'-(1,8-Dioxo-1,8-octanediyl)bis-2,5-pyrrolidinedione (BioDeep_00000184846)

   

human metabolite blood metabolite


代谢物信息卡片


1-[8-(2,5-dioxopyrrolidin-1-yl)-8-oxooctanoyl]pyrrolidine-2,5-dione

化学式: C16H20N2O6 (336.13213)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(=O)N(C1=O)C(=O)CCCCCCC(=O)N2C(=O)CCC2=O
InChI: InChI=1S/C16H20N2O6/c19-11(17-13(21)7-8-14(17)22)5-3-1-2-4-6-12(20)18-15(23)9-10-16(18)24/h1-10H2

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D003432 - Cross-Linking Reagents

同义名列表

3 个代谢物同义名

1-[8-(2,5-dioxopyrrolidin-1-yl)-8-oxooctanoyl]pyrrolidine-2,5-dione; 1,1-(1,8-Dioxo-1,8-octanediyl)bis-2,5-pyrrolidinedione; Disuccinimidyl suberate



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Evelyn Rampler, Thomas Stranzl, Zsuzsanna Orban-Nemeth, David Maria Hollenstein, Otto Hudecz, Peter Schlögelhofer, Karl Mechtler. Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1. Journal of proteome research. 2015 12; 14(12):5048-62. doi: 10.1021/acs.jproteome.5b00903. [PMID: 26535604]
  • Youzhi Jin, Pamela J McFie, Shanna L Banman, Curtis Brandt, Scot J Stone. Diacylglycerol acyltransferase-2 (DGAT2) and monoacylglycerol acyltransferase-2 (MGAT2) interact to promote triacylglycerol synthesis. The Journal of biological chemistry. 2014 Oct; 289(41):28237-48. doi: 10.1074/jbc.m114.571190. [PMID: 25164810]
  • Florina Scurtu, Oana Zolog, Bianca Iacob, Radu Silaghi-Dumitrescu. Hemoglobin-albumin cross-linking with disuccinimidyl suberate (DSS) and/or glutaraldehyde for blood substitutes. Artificial cells, nanomedicine, and biotechnology. 2014 Feb; 42(1):13-7. doi: 10.3109/21691401.2012.762652. [PMID: 23342991]
  • Karen Bernard, Kevin L Kirk. Cross-linking of ΔF508-CFTR promotes its trafficking to the plasma membrane. Channels (Austin, Tex.). 2010 Jul; 4(4):251-4. doi: 10.4161/chan.4.4.12198. [PMID: 20581470]
  • Faoud T Ishmael, Vincent K Shier, Susan S Ishmael, Judith S Bond. Intersubunit and domain interactions of the meprin B metalloproteinase. Disulfide bonds and protein-protein interactions in the MAM and TRAF domains. The Journal of biological chemistry. 2005 Apr; 280(14):13895-901. doi: 10.1074/jbc.m414218200. [PMID: 15695509]
  • Xiuling Lu, Chunyang Zheng, Yuhong Xu, Zhiguo Su. Disuccinimidyl suberate cross-linked hemoglobin as a novel red blood cell substitute. Science in China. Series C, Life sciences. 2005 Feb; 48(1):49-60. doi: 10.1360/04yc0014. [PMID: 15844357]
  • Martina Lahmann, Linnéa Bülow, Peter Teodorovic, Helena Gybäck, Stefan Oscarson. Synthesis of the Lewis b hexasaccharide and HSA-conjugates thereof. Glycoconjugate journal. 2004; 21(5):251-6. doi: 10.1023/b:glyc.0000045097.19353.73. [PMID: 15486457]
  • Martin R Pool, Joachim Stumm, Tudor A Fulga, Irmgard Sinning, Bernhard Dobberstein. Distinct modes of signal recognition particle interaction with the ribosome. Science (New York, N.Y.). 2002 Aug; 297(5585):1345-8. doi: 10.1126/science.1072366. [PMID: 12193787]
  • Nathalie Roudier, Pascal Bailly, Pierre Gane, Nicole Lucien, Renée Gobin, Jean-Pierre Cartron, Pierre Ripoche. Erythroid expression and oligomeric state of the AQP3 protein. The Journal of biological chemistry. 2002 Mar; 277(10):7664-9. doi: 10.1074/jbc.m105411200. [PMID: 11751877]
  • D M Manley, M E McComb, H Perreault, L J Donald, H W Duckworth, J D O'Neil. Secondary structure and oligomerization of the E. coli glycerol facilitator. Biochemistry. 2000 Oct; 39(40):12303-11. doi: 10.1021/bi000703t. [PMID: 11015209]
  • I Biswas, R Vijayvargia. Heteroduplex DNA and ATP induced conformational changes of a MutS mismatch repair protein from Thermus aquaticus. The Biochemical journal. 2000 May; 347 Pt 3(?):881-6. doi: 10.1042/bj3470881. [PMID: 10769195]
  • T E Zewert, M G Harrington. Cross-linked poly(N-acetylethylenimine) as an isoelectric focusing matrix. Electrophoresis. 1999 Jun; 20(7):1339-48. doi: 10.1002/(sici)1522-2683(19990601)20:7<1339::aid-elps1339>3.0.co;2-7. [PMID: 10424455]
  • S R Haward, J A Napier, J C Gray. Chloroplast SecA functions as a membrane-associated component of the Sec-like protein translocase of pea chloroplasts. European journal of biochemistry. 1997 Sep; 248(3):724-30. doi: 10.1111/j.1432-1033.1997.00724.x. [PMID: 9342223]
  • K E Matlack, K Plath, B Misselwitz, T A Rapoport. Protein transport by purified yeast Sec complex and Kar2p without membranes. Science (New York, N.Y.). 1997 Aug; 277(5328):938-41. doi: 10.1126/science.277.5328.938. [PMID: 9252322]
  • G Chandrasekher, R J Cenedella. Properties of alpha-crystallin bound to lens membrane: probing organization at the membrane surface. Experimental eye research. 1997 Mar; 64(3):423-30. doi: 10.1006/exer.1996.0228. [PMID: 9196394]
  • D Barbeau, R Bouley, E Escher. Molecular weight determination of the hepatic vasopressin receptor with a high-affinity photoprobe. International journal of peptide and protein research. 1996 Oct; 48(4):364-73. doi: 10.1111/j.1399-3011.1996.tb00853.x. [PMID: 8919057]
  • J L Spivak, L S Avedissian, J H Pierce, D Williams, W D Hankins, R A Jensen. Isolation of the full-length murine erythropoietin receptor using a baculovirus expression system. Blood. 1996 Feb; 87(3):926-37. doi: 10.1182/blood.v87.3.926.bloodjournal873926. [PMID: 8562964]
  • K M Giangiacomo, M Garcia-Calvo, H G Knaus, T J Mullmann, M L Garcia, O McManus. Functional reconstitution of the large-conductance, calcium-activated potassium channel purified from bovine aortic smooth muscle. Biochemistry. 1995 Dec; 34(48):15849-62. doi: 10.1021/bi00048a031. [PMID: 7495817]
  • P Franzén, C H Heldin, K Miyazono. The GS domain of the transforming growth factor-beta type I receptor is important in signal transduction. Biochemical and biophysical research communications. 1995 Feb; 207(2):682-9. doi: 10.1006/bbrc.1995.1241. [PMID: 7864860]
  • S Harada, R M Smith, J A Smith, N Shah, L Jarett. Demonstration of specific insulin binding to cytosolic proteins in H35 hepatoma cells, rat liver and skeletal muscle. The Biochemical journal. 1995 Feb; 306 ( Pt 1)(?):21-8. doi: 10.1042/bj3060021. [PMID: 7864812]
  • G R Hicks, N V Raikhel. Nuclear localization signal binding proteins in higher plant nuclei. Proceedings of the National Academy of Sciences of the United States of America. 1995 Jan; 92(3):734-8. doi: 10.1073/pnas.92.3.734. [PMID: 7846044]
  • M A Goldsmith, W Xu, M C Amaral, E S Kuczek, W C Greene. The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements. The Journal of biological chemistry. 1994 May; 269(20):14698-704. doi: 10.1016/s0021-9258(17)36681-4. [PMID: 8182077]
  • M C Gelato, D Alexander, K Marsh. Differential tissue regulation of insulin-like growth factor binding proteins in experimental diabetes mellitus in the rat. Diabetes. 1992 Dec; 41(12):1511-9. doi: 10.2337/diab.41.12.1511. [PMID: 1280236]
  • M Del Rosso, N Pedersen, G Fibbi, M Pucci, G Dini, E Anichini, F Blasi. Selective localization of receptors for urokinase amino-terminal fragment at substratum contact sites of an in vitro-established line of human epidermal cells. Experimental cell research. 1992 Dec; 203(2):427-34. doi: 10.1016/0014-4827(92)90017-3. [PMID: 1333982]
  • D G Lowe. Human natriuretic peptide receptor-A guanylyl cyclase is self-associated prior to hormone binding. Biochemistry. 1992 Nov; 31(43):10421-5. doi: 10.1021/bi00158a001. [PMID: 1358197]
  • K Yoshino, N Suzuki. Two classes of receptor specific for sperm-activating peptide III in sand-dollar spermatozoa. European journal of biochemistry. 1992 Jun; 206(3):887-93. doi: 10.1111/j.1432-1033.1992.tb16997.x. [PMID: 1318839]
  • J Maury, A F Burnol, M Loizeau, T Issad, J Girard, P Ferré. Insulin receptor function is preserved in a physiological state of hypoinsulinemia and insulin resistance. The American journal of physiology. 1992 Jun; 262(6 Pt 1):E818-25. doi: 10.1152/ajpendo.1992.262.6.e818. [PMID: 1319678]
  • A Yokota, N Tsujimoto. Characterization of ribulose-1,5-bisphosphate carboxylase/oxygenase carrying ribulose 1,5-bisphosphate at its regulatory sites and the mechanism of interaction of this form of the enzyme with ribulose-1,5-bisphosphate-carboxylase/oxygenase activase. European journal of biochemistry. 1992 Mar; 204(2):901-9. doi: 10.1111/j.1432-1033.1992.tb16710.x. [PMID: 1541300]
  • J C Kermode, A W DeLuca, A Zilberman, J Valliere, S M Shreeve. Evidence for the formation of a functional complex between vasoactive intestinal peptide, its receptor, and Gs in lung membranes. The Journal of biological chemistry. 1992 Feb; 267(5):3382-8. doi: 10.1016/s0021-9258(19)50742-6. [PMID: 1310685]
  • K Cissewski, M Wolf, A C Moses. Characterization of insulin-like growth factor receptors in human thyroid tissue. Receptor. 1992; 2(3):145-53. doi: NULL. [PMID: 1472949]
  • N Casadevall, C Lacombe, O Muller, S Gisselbrecht, P Mayeux. Multimeric structure of the membrane erythropoietin receptor of murine erythroleukemia cells (Friend cells). Cross-linking of erythropoietin with the spleen focus-forming virus envelope protein. The Journal of biological chemistry. 1991 Aug; 266(24):16015-20. doi: NULL. [PMID: 1651930]
  • P O'Grady, M D Kuo, J J Baldassare, S S Huang, J S Huang. Purification of a new type high molecular weight receptor (type V receptor) of transforming growth factor beta (TGF-beta) from bovine liver. Identification of the type V TGF-beta receptor in cultured cells. The Journal of biological chemistry. 1991 May; 266(13):8583-9. doi: 10.1016/s0021-9258(18)93014-0. [PMID: 1850748]
  • P N De Graan, A B Oestreicher, M De Wit, M Kroef, L H Schrama, W H Gispen. Evidence for the binding of calmodulin to endogenous B-50 (GAP-43) in native synaptosomal plasma membranes. Journal of neurochemistry. 1990 Dec; 55(6):2139-41. doi: 10.1111/j.1471-4159.1990.tb05808.x. [PMID: 2146368]
  • S J Rinderle, I J Goldstein, E E Remsen. Physicochemical properties of amaranthin, the lectin from Amaranthus caudatus seeds. Biochemistry. 1990 Nov; 29(46):10555-61. doi: 10.1021/bi00498a019. [PMID: 2271665]
  • W W Stewart, M A Kerr. The specificity of the human neutrophil IgA receptor (Fc alpha R) determined by measurement of chemiluminescence induced by serum or secretory IgA1 or IgA2. Immunology. 1990 Nov; 71(3):328-34. doi: NULL. [PMID: 2269470]
  • M Emtner, P Roos. Identification and partial characterization of a growth hormone-binding protein in rat serum. Acta endocrinologica. 1990 Mar; 122(3):296-302. doi: 10.1530/acta.0.1220296. [PMID: 2158195]
  • M C Tzeng, M J Hseu, C H Yen. Taipoxin-binding protein on synaptic membranes: identification by affinity labeling. Biochemical and biophysical research communications. 1989 Dec; 165(2):689-94. doi: 10.1016/s0006-291x(89)80021-x. [PMID: 2597156]
  • A Hildebrand, K T Preissner, G Müller-Berghaus, H Teschemacher. A novel beta-endorphin binding protein. Complement S protein (= vitronectin) exhibits specific non-opioid binding sites for beta-endorphin upon interaction with heparin or surfaces. The Journal of biological chemistry. 1989 Sep; 264(26):15429-34. doi: NULL. [PMID: 2475499]
  • O Lascols, J Capeau, G Cherqui, M Caron, J Bachimont, J Picard. Glycosylation characteristics of the mouse liver lactogenic receptor. Molecular and cellular endocrinology. 1989 Aug; 65(1-2):145-55. doi: 10.1016/0303-7207(89)90175-5. [PMID: 2506088]
  • A Møldrup, N Billestrup, N A Thorn, A Lernmark, J H Nielsen. Multiple growth hormone-binding proteins are expressed on insulin-producing cells. Molecular endocrinology (Baltimore, Md.). 1989 Aug; 3(8):1173-82. doi: 10.1210/mend-3-8-1173. [PMID: 2674691]
  • T Funahashi, S Yokoyama, A Yamamoto. Association of apolipoprotein E with the low density lipoprotein receptor: demonstration of its co-operativity on lipid microemulsion particles. Journal of biochemistry. 1989 Apr; 105(4):582-7. doi: 10.1093/oxfordjournals.jbchem.a122708. [PMID: 2760017]
  • M A Sturm, C A Conover, H Pham, R G Rosenfeld. Insulin-like growth factor receptors and binding protein in rat neuroblastoma cells. Endocrinology. 1989 Jan; 124(1):388-96. doi: 10.1210/endo-124-1-388. [PMID: 2462492]
  • J F Haskell, D J Pillion, E Meezan. Specific, high affinity receptors for insulin-like growth factor II in the rat kidney glomerulus. Endocrinology. 1988 Aug; 123(2):774-80. doi: 10.1210/endo-123-2-774. [PMID: 2969326]
  • B Barenton, B A Patel, M N Khan, H J Guyda, B I Posner. Insulin-like growth factor-binding proteins in hypophysectomized rat liver: characterization and subcellular localization. Endocrinology. 1988 Jun; 122(6):2499-507. doi: 10.1210/endo-122-6-2499. [PMID: 2967175]
  • M L Bayne, J Applebaum, G G Chicchi, N S Hayes, B G Green, M A Cascieri. Structural analogs of human insulin-like growth factor I with reduced affinity for serum binding proteins and the type 2 insulin-like growth factor receptor. The Journal of biological chemistry. 1988 May; 263(13):6233-9. doi: 10.1016/s0021-9258(18)68777-0. [PMID: 2966152]
  • K Siminoski, R A Murphy. Detection of molecules with nerve growth factor binding activity in medium conditioned by L-929 fibroblasts. Brain research. 1987 Dec; 435(1-2):273-82. doi: 10.1016/0006-8993(87)91610-6. [PMID: 2827854]
  • S I Ymer, A C Herington. Structural studies on membrane-bound and soluble growth-hormone-binding proteins of rabbit liver. The Biochemical journal. 1987 Mar; 242(3):713-20. doi: 10.1042/bj2420713. [PMID: 3593272]
  • J R Zysk, M J Cronin, J M Anderson, M O Thorner. Cross-linking of a growth hormone releasing factor-binding protein in anterior pituitary cells. The Journal of biological chemistry. 1986 Dec; 261(36):16781-4. doi: . [PMID: 3023363]
  • R Friesel, W H Burgess, T Mehlman, T Maciag. The characterization of the receptor for endothelial cell growth factor by covalent ligand attachment. The Journal of biological chemistry. 1986 Jun; 261(17):7581-4. doi: NULL. [PMID: 3519611]
  • R McQuade, C G Thomas, S N Nayfeh. Covalent crosslinking of thyrotropin to thyroid plasma membrane receptors: subunit composition of the thyrotropin receptor. Archives of biochemistry and biophysics. 1986 Apr; 246(1):52-62. doi: 10.1016/0003-9861(86)90448-0. [PMID: 3008661]
  • S Yokoyama, Y Kawai, S Tajima, A Yamamoto. Behavior of human apolipoprotein E in aqueous solutions and at interfaces. The Journal of biological chemistry. 1985 Dec; 260(30):16375-82. doi: 10.1016/s0021-9258(17)36247-6. [PMID: 4066713]
  • J Mazella, C Y Kwan, P Kitabgi, J P Vincent. Covalent labeling of neurotensin receptors in rat gastric fundus plasma membranes. Peptides. 1985 Nov; 6(6):1137-41. doi: 10.1016/0196-9781(85)90440-1. [PMID: 3010256]
  • R Pfaller, H Freitag, M A Harmey, R Benz, W Neupert. A water-soluble form of porin from the mitochondrial outer membrane of Neurospora crassa. Properties and relationship to the biosynthetic precursor form. The Journal of biological chemistry. 1985 Jul; 260(13):8188-93. doi: 10.1016/s0021-9258(17)39580-7. [PMID: 2989279]
  • J Massagué, B Like. Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines. The Journal of biological chemistry. 1985 Mar; 260(5):2636-45. doi: NULL. [PMID: 2982829]
  • M Hatanaka, N Yumoto, T Sakihama, T Murachi. Evidence for heterodimeric nature of calpain molecules as studied by cross-linking modification. Biochemistry international. 1985 Feb; 10(2):187-93. doi: NULL. [PMID: 2986635]
  • C L Wood, M S O'Dorisio. Covalent cross-linking of vasoactive intestinal polypeptide to its receptors on intact human lymphoblasts. The Journal of biological chemistry. 1985 Jan; 260(2):1243-7. doi: 10.1016/s0021-9258(20)71235-4. [PMID: 2981838]
  • C A Rinehart, K Y Chen. Identification of the insulin receptor in undifferentiated and differentiated NB-15 mouse neuroblastoma cells by affinity labeling. Biochimica et biophysica acta. 1984 Dec; 802(3):515-21. doi: 10.1016/0304-4165(84)90371-4. [PMID: 6391556]
  • J F Haskell, E Meezan, D J Pillion. Identification and characterization of the insulin receptor of bovine retinal microvessels. Endocrinology. 1984 Aug; 115(2):698-704. doi: 10.1210/endo-115-2-698. [PMID: 6378598]
  • A J D'Ercole, J R Wilkins. Affinity labeled somatomedin-C-binding proteins in rat sera. Endocrinology. 1984 Apr; 114(4):1141-4. doi: 10.1210/endo-114-4-1141. [PMID: 6200313]
  • C Carter-Su, J Schwartz, G Kikuchi. Identification of a high affinity growth hormone receptor in rat adipocyte membranes. The Journal of biological chemistry. 1984 Jan; 259(2):1099-104. doi: 10.1016/s0021-9258(17)43571-x. [PMID: 6319377]
  • P Arner, K Einarsson, L Backman, K Nilsell, K M Lerea, J N Livingston. Studies of liver insulin receptors in non-obese and obese human subjects. The Journal of clinical investigation. 1983 Nov; 72(5):1729-36. doi: 10.1172/jci111132. [PMID: 6355185]
  • M D Baron, P H Sönksen. Elucidation of the quaternary structure of the insulin receptor. The Biochemical journal. 1983 Apr; 212(1):79-84. doi: 10.1042/bj2120079. [PMID: 6870858]
  • C Sakamoto, J A Williams, K Y Wong, I D Goldfine. The CCK receptor on pancreatic plasma membranes: binding characteristics and covalent cross-linking. FEBS letters. 1983 Jan; 151(1):63-6. doi: 10.1016/0014-5793(83)80343-3. [PMID: 6297990]
  • M Kasuga, E Van Obberghen, S P Nissley, M M Rechler. Demonstration of two subtypes of insulin-like growth factor receptors by affinity cross-linking. The Journal of biological chemistry. 1981 Jun; 256(11):5305-8. doi: 10.1016/s0021-9258(19)69196-9. [PMID: 6263874]
  • J Massague, B J Guillette, M P Czech. Affinity labeling of multiplication stimulating activity receptors in membranes from rat and human tissues. The Journal of biological chemistry. 1981 Mar; 256(5):2122-5. doi: NULL. [PMID: 6257700]