2-[(3-Chlorophenyl)amino]phenylacetic acid (BioDeep_00000184806)
human metabolite blood metabolite
代谢物信息卡片
化学式: C14H12ClNO2 (261.0556522)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 57.89%
分子结构信息
SMILES: C1=CC=C(C(=C1)CC(=O)O)NC2=CC(=CC=C2)Cl
InChI: InChI=1S/C14H12ClNO2/c15-11-5-3-6-12(9-11)16-13-7-2-1-4-10(13)8-14(17)18/h1-7,9,16H,8H2,(H,17,18)
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Margo P Cohen, Elizabeth A Shea, Van-Yu Wu. Inhibiting low-density lipoprotein glycation ameliorates increased cholesteryl ester synthesis in macrophages and hypercholesterolemia and aortic lipid peroxidation in streptozotocin diabetic rats.
Metabolism: clinical and experimental.
2010 May; 59(5):658-63. doi:
10.1016/j.metabol.2009.09.010
. [PMID: 19922964] - Laurence Kennedy, Maria Pilar Solano, Luigi Meneghini, Margaret Lo, Margo P Cohen. Anti-glycation and anti-albuminuric effects of GLY-230 in human diabetes.
American journal of nephrology.
2010; 31(2):110-6. doi:
10.1159/000259897
. [PMID: 19923796] - Margo P Cohen, Clyde W Shearman. Reduction of Abeta42 in brains of transgenic APPswe mice by 2-3-chlorophenylaminophenylacetate.
Clinical and experimental pharmacology & physiology.
2009 Nov; 36(11):1099-103. doi:
10.1111/j.1440-1681.2009.05201.x
. [PMID: 19413589] - Margo P Cohen, Elizabeth Hud, Van-Yu Wu, Clyde W Shearman. Amelioration of diabetes-associated abnormalities in the vitreous fluid by an inhibitor of albumin glycation.
Investigative ophthalmology & visual science.
2008 Nov; 49(11):5089-93. doi:
10.1167/iovs.08-1993
. [PMID: 18599566] - Margo P Cohen, Gregory T Lautenslager, Elizabeth Hud, Elizabeth Shea, Amy Wang, Sheldon Chen, Clyde W Shearman. Inhibiting albumin glycation attenuates dysregulation of VEGFR-1 and collagen IV subchain production and the development of renal insufficiency.
American journal of physiology. Renal physiology.
2007 Feb; 292(2):F789-95. doi:
10.1152/ajprenal.00201.2006
. [PMID: 17018845] - Margo P Cohen, Fuad N Ziyadeh, Soon Won Hong, Clyde W Shearman, Elizabeth Hud, Gregory T Lautenslager, M Carmen Iglesias-de la Cruz, Sheldon Chen. Inhibiting albumin glycation in vivo ameliorates glomerular overexpression of TGF-beta1.
Kidney international.
2002 Jun; 61(6):2025-32. doi:
10.1046/j.1523-1755.2002.00352.x
. [PMID: 12028443]