Furanylfentanyl (BioDeep_00000184706)

 

Secondary id: BioDeep_00000272117

human metabolite blood metabolite


代谢物信息卡片


N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide

化学式: C24H26N2O2 (374.1994176)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 33.33%

分子结构信息

SMILES: C1CN(CCC1N(C2=CC=CC=C2)C(=O)C3=CC=CO3)CCC4=CC=CC=C4
InChI: InChI=1S/C24H26N2O2/c27-24(23-12-7-19-28-23)26(21-10-5-2-6-11-21)22-14-17-25(18-15-22)16-13-20-8-3-1-4-9-20/h1-12,19,22H,13-18H2

描述信息

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics

同义名列表

2 个代谢物同义名

N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide; Furanylfentanyl



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Neeraj Chhabra, Lum Rizvanolli, Arkady Rasin, Granger Marsden, Keiki Hinami, Steven E Aks. A cross-sectional analysis of fentanyl analog exposures among living patients. The American journal of drug and alcohol abuse. 2021 05; 47(3):344-349. doi: 10.1080/00952990.2021.1891420. [PMID: 33798014]
  • Jean Jung, Allan Kolodziej, Elise Pape, Michael Bisch, Lucie Javot, Valérie Gibaja, Jean-Yves Jouzeau, Julien Scala-Bertola, Nicolas Gambier. Multiplex detection of 14 fentanyl analogues and U-47700 in biological samples: Application to a panel of French hospitalized patients. Forensic science international. 2020 Dec; 317(?):110437. doi: 10.1016/j.forsciint.2020.110437. [PMID: 33007729]
  • Kaitlyn B Palmquist, Madeleine J Swortwood. Quantification of Furanylfentanyl and its Metabolites in Human and Rat Plasma Using LC-MS-MS. Journal of analytical toxicology. 2020 Jul; 44(6):589-595. doi: 10.1093/jat/bkaa013. [PMID: 32064536]
  • Francesca Freni, Sara Pezzella, Claudia Vignali, Matteo Moretti, Simone Cisini, Chiara Rossetti, Rossana Ravizza, Marco Motta, Angelo Groppi, Luca Morini. A case report on potential postmortem redistribution of furanyl fentanyl and 4-ANPP. Forensic science international. 2019 Nov; 304(?):109915. doi: 10.1016/j.forsciint.2019.109915. [PMID: 31416646]
  • Robert G Hendrickson, Peter Akpunonu, Adrienne R Hughes, Roy Gerona. Highly potent fentanyl analogs: apnea from exposure to small quantities of ß-hydroxyfentanyl and furanylfentanyl. Clinical toxicology (Philadelphia, Pa.). 2019 Sep; 57(9):813-815. doi: 10.1080/15563650.2018.1558233. [PMID: 30888883]
  • Christine Nash, Danielle Butzbach, Peter Stockham, Timothy Scott, Greg Abroe, Ben Painter, John Gilbert, Chris Kostakis. A Fatality Involving Furanylfentanyl and MMMP, with Presumptive Identification of Three MMMP Metabolites in Urine. Journal of analytical toxicology. 2019 May; 43(4):291-298. doi: 10.1093/jat/bky099. [PMID: 30566582]
  • Alex J Krotulski, Donna M Papsun, Melissa Friscia, Jennifer L Swartz, Brian D Holsey, Barry K Logan. Fatality Following Ingestion of Tetrahydrofuranylfentanyl, U-49900 and Methoxy-Phencyclidine. Journal of analytical toxicology. 2018 Apr; 42(3):e27-e32. doi: 10.1093/jat/bkx092. [PMID: 29186585]
  • Hana F H Martucci, Eric A Ingle, Michael D Hunter, Luke N Rodda. Distribution of furanyl fentanyl and 4-ANPP in an accidental acute death: A case report. Forensic science international. 2018 Feb; 283(?):e13-e17. doi: 10.1016/j.forsciint.2017.12.005. [PMID: 29254806]
  • Dina M Swanson, Laura S Hair, Selly R Strauch Rivers, Brianna C Smyth, Sara C Brogan, Alexis D Ventoso, Samantha L Vaccaro, Julia M Pearson. Fatalities Involving Carfentanil and Furanyl Fentanyl: Two Case Reports. Journal of analytical toxicology. 2017 Jul; 41(6):498-502. doi: 10.1093/jat/bkx037. [PMID: 28575422]
  • Melissa M Goggin, An Nguyen, Gregory C Janis. Identification of Unique Metabolites of the Designer Opioid Furanyl Fentanyl. Journal of analytical toxicology. 2017 Jun; 41(5):367-375. doi: 10.1093/jat/bkx022. [PMID: 28369517]
  • Camille Richeval, Thomas Gicquel, Chloe Hugbart, Brendan Le Dare, Delphine Allorge, Isabelle Morel, Jean-Michel Gaulier. In vitro Characterization of NPS Metabolites Produced by Human Liver Microsomes and the HepaRG Cell Line Using Liquid Chromatographyhigh Resolution Mass Spectrometry (LC-HRMS) Analysis: Application to Furanyl Fentanyl. Current pharmaceutical biotechnology. 2017; 18(10):806-814. doi: 10.2174/1389201018666171122124401. [PMID: 29173157]