L-Alaninamide,N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)- (BioDeep_00000184142)

   

human metabolite blood metabolite


代谢物信息卡片


N-[1-({1-[(2-aminoethyl)-C-hydroxycarbonimidoyl]ethyl}-C-hydroxycarbonimidoyl)-2-(naphthalen-2-yl)ethyl]-2-[(dihydroxycarbonimidoyl)methyl]-4-methylpentanimidate

化学式: C26H37N5O5 (499.2795)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 100%

分子结构信息

SMILES: CC(C)CC(CC(=O)NO)C(=O)NC(CC1=CC2=CC=CC=C2C=C1)C(=O)NC(C)C(=O)NCCN
InChI: InChI=1S/C26H37N5O5/c1-16(2)12-21(15-23(32)31-36)25(34)30-22(26(35)29-17(3)24(33)28-11-10-27)14-18-8-9-19-6-4-5-7-20(19)13-18/h4-9,13,16-17,21-22,36H,10-12,14-15,27H2,1-3H3,(H,28,33)(H,29,35)(H,30,34)(H,31,32)

描述信息

同义名列表

7 个代谢物同义名

N-[1-({1-[(2-aminoethyl)-C-hydroxycarbonimidoyl]ethyl}-C-hydroxycarbonimidoyl)-2-(naphthalen-2-yl)ethyl]-2-[(dihydroxycarbonimidoyl)methyl]-4-methylpentanimidate; N-[1-({1-[(2-aminoethyl)carbamoyl]ethyl}carbamoyl)-2-(naphthalen-2-yl)ethyl]-N-hydroxy-2-(2-methylpropyl)butanediamide; N-[1-({1-[(2-aminoethyl)carbamoyl]ethyl}carbamoyl)-2-(naphthalen-2-yl)ethyl]-N-hydroxy-2-(2-methylpropyl)succinamide; L-Alaninamide,N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-; N-((2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2-naphthyl)alanylalanine, 2-aminoethylamide; TAPI (inhibitor); TAPI-1



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Archit Verma, Siddhartha G Jena, Danielle R Isakov, Kazuhiro Aoki, Jared E Toettcher, Barbara E Engelhardt. A self-exciting point process to study multicellular spatial signaling patterns. Proceedings of the National Academy of Sciences of the United States of America. 2021 08; 118(32):. doi: 10.1073/pnas.2026123118. [PMID: 34362843]
  • Cynthia C Tsui, Nicole A Gabreski, Sarah J Hein, Brian A Pierchala. Lipid Rafts Are Physiologic Membrane Microdomains Necessary for the Morphogenic and Developmental Functions of Glial Cell Line-Derived Neurotrophic Factor In Vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Sep; 35(38):13233-43. doi: 10.1523/jneurosci.2935-14.2015. [PMID: 26400951]
  • Kazuhiro Yamamoto, Kaoru Miyazaki, Shouichi Higashi. Pericellular proteolysis by matrix metalloproteinase-7 is differentially modulated by cholesterol sulfate, sulfatide, and cardiolipin. The FEBS journal. 2014 Aug; 281(15):3346-56. doi: 10.1111/febs.12865. [PMID: 24903600]
  • Esam S B Salem, Nadja Grobe, Khalid M Elased. Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice. American journal of physiology. Renal physiology. 2014 Mar; 306(6):F629-39. doi: 10.1152/ajprenal.00516.2013. [PMID: 24452639]
  • Mika Terao, Hiroyuki Murota, Shun Kitaba, Ichiro Katayama. Tumor necrosis factor-alpha processing inhibitor-1 inhibits skin fibrosis in a bleomycin-induced murine model of scleroderma. Experimental dermatology. 2010 Jan; 19(1):38-43. doi: 10.1111/j.1600-0625.2009.00973.x. [PMID: 19758314]
  • Boris K Pliyev. Activated human neutrophils rapidly release the chemotactically active D2D3 form of the urokinase-type plasminogen activator receptor (uPAR/CD87). Molecular and cellular biochemistry. 2009 Jan; 321(1-2):111-22. doi: 10.1007/s11010-008-9925-z. [PMID: 18830568]
  • Shougang Zhuang, Gilbert R Kinsey, Kyle Rasbach, Rick G Schnellmann. Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells. American journal of physiology. Renal physiology. 2008 Mar; 294(3):F459-68. doi: 10.1152/ajprenal.00473.2007. [PMID: 18171996]
  • Wolfgang Bergmeier, Crystal L Piffath, Guiying Cheng, Vandana S Dole, Yuhua Zhang, Ulrich H von Andrian, Denisa D Wagner. Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo. Circulation research. 2004 Oct; 95(7):677-83. doi: 10.1161/01.res.0000143899.73453.11. [PMID: 15345652]
  • Katharine A Hintz, Athos J Rassias, Kathleen Wardwell, Marcia L Moss, Peter M Morganelli, Patricia A Pioli, Alice L Givan, Paul K Wallace, Mark P Yeager, Paul M Guyre. Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163. Journal of leukocyte biology. 2002 Oct; 72(4):711-7. doi: NULL. [PMID: 12377940]