Thiazole (BioDeep_00000018414)
human metabolite Endogenous
代谢物信息卡片
Photinus luciferin
化学式: C3H3NS (84.9986198)
中文名称: 噻唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CSC=N1
InChI: InChI=1S/C3H3NS/c1-2-5-3-4-1/h1-3H
描述信息
Thiazole is a flavouring ingredient The thiazole moiety is a crucial part of vitamin B1 (thiamine) and epothilone. Other important thiazoles are benzothiazoles, for example, the firefly chemical luciferin. Thiazole, or 1,3-thiazole, is a clear to pale yellow flammable liquid with a pyridine-like odor and the molecular formula C3H3NS. It is a 5-membered ring, in which two of the vertices of the ring are nitrogen and sulfur, and the other three are carbons. Thiazoles are a class of organic compounds related to azoles with a common thiazole functional group. Thiazoles are aromatic
Flavouring ingredient
同义名列表
7 个代谢物同义名
Photinus luciferin; 5H-1,3-Thiazole; 1,3-Thiazole; FEMA 3615; THIAZOLE; LOM; tz
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:43732
- PubChem: 9256
- HMDB: HMDB0029713
- ChEMBL: CHEMBL15605
- Wikipedia: Thiazole
- MeSH: Thiazoles
- foodb: FDB000907
- chemspider: 8899
- CAS: 288-47-1
- PMhub: MS000007793
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sayantani Nanda, Abhratanu Ganguly, Moutushi Mandi, Kanchana Das, Siddhartha Ghanty, Gopal Biswas, Prem Rajak. Chronic sub-lethal exposure to clothianidin triggers organismal and sub-organismal-level health hazards in a non-target organism, Drosophila melanogaster.
The Science of the total environment.
2024 Jul; 932(?):172783. doi:
10.1016/j.scitotenv.2024.172783. [PMID: 38679102] - Mi Liang, Zhong-Shi Lyu, Yuan-Yuan Zhang, Shu-Qian Tang, Tong Xing, Yu-Hong Chen, Yu Wang, Qian Jiang, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang, Yuan Kong. Activation of PPARδ in bone marrow endothelial progenitor cells improves their hematopoiesis-supporting ability after myelosuppressive injury.
Cancer letters.
2024 Jun; 592(?):216937. doi:
10.1016/j.canlet.2024.216937. [PMID: 38704134] - Zonghan Xu, Xiang Cheng, Hongyun Cui, Linmin Cao, Yaping Song, Xihao Chang, Dandan Wang, Xianhai Lv. Design, selective synthesis and biological activities evaluation of novel thiazol-2-ylbenzamide and thiazole-2-ylbenzimidoyl chloride derivatives.
Bioorganic chemistry.
2024 Jun; 147(?):107333. doi:
10.1016/j.bioorg.2024.107333. [PMID: 38599055] - Yue Zhang, Jing Li, Hongwei Yang, Kun Li, Haolin Yuan, Ziqiao Xue, Liangfu Tang, Zhijin Fan. Fungicidal Activity of New Pyrrolo[2,3-d]thiazoles and Their Potential Action on the Tryptophan Metabolic Pathway and Wax Biosynthesis.
Journal of agricultural and food chemistry.
2024 May; 72(21):11990-12002. doi:
10.1021/acs.jafc.4c00930. [PMID: 38757490] - Lei Zhu, Yilin Shi, Zhelong Feng, Dingyi Yuan, Shiduo Guo, Yuxia Wang, Haowen Shen, Yan Li, Fang Yan, Yajing Wang. Fatostatin promotes anti-tumor immunity by reducing SREBP2 mediated cholesterol metabolism in tumor-infiltrating T lymphocytes.
European journal of pharmacology.
2024 May; 971(?):176519. doi:
10.1016/j.ejphar.2024.176519. [PMID: 38522641] - Zengxin Li, Wenhong Li, Qing Mu, Yicheng Zhu, Weiwei Qin, Xiaobin Shi, Yueping He. Rifampicin synergizes the toxicity of insecticides against the green peach aphid, Myzus persicae.
Ecotoxicology and environmental safety.
2024 May; 276(?):116291. doi:
10.1016/j.ecoenv.2024.116291. [PMID: 38581910] - Xuezhu Xiang, Yue Xie, Di Tian, Zhenguo Chen, Xiaohui Yi, Ziyan Chen, Minzhi Huang. Microbial degradation mechanism and pathway of the insecticide thiamethoxam by isolated Bacillus Cereus from activated sludge.
Environmental research.
2024 Apr; 246(?):117929. doi:
10.1016/j.envres.2023.117929. [PMID: 38157972] - Kristen Ward, Leslie Citrome. Tolerability and safety outcomes of first-line oral second-generation antipsychotics in patients with schizophrenia.
Expert opinion on drug safety.
2024 Apr; 23(4):399-409. doi:
10.1080/14740338.2024.2328812. [PMID: 38467517] - Jing Zhang, Yunyun Wang, Shanbaga Wurjihu, Haonan Ruan, Ying Huang, Mengyue Guo, Dandan Kong, Jiaoyang Luo, Meihua Yang. Comprehensive analysis of neonicotinoids in Chinese commercial honey and pollen: A corresponding health risk assessment for non-targeted organisms.
The Science of the total environment.
2024 Apr; 919(?):170937. doi:
10.1016/j.scitotenv.2024.170937. [PMID: 38360305] - Yanhua Lu, Lijun Gao, Jinling Hu, Xiaoxue Liu, Dong Jiang, Weixing Cao, Tingbo Dai, Zhongwei Tian. Low nitrogen priming improves nitrogen uptake and assimilation adaptation to nitrogen deficit stress in wheat seedling.
Planta.
2024 Mar; 259(5):107. doi:
10.1007/s00425-024-04385-3. [PMID: 38554244] - Jiali Ge, Xiangyu Hou, Li Liu, Qing Deng, Bibai Du, Lixi Zeng. Comprehensive Identification and Ubiquitous Occurrence of Eight Classes of Rubber-Derived Vulcanization Accelerators in Urban Dusts.
Environmental science & technology.
2024 Mar; 58(11):5117-5128. doi:
10.1021/acs.est.3c09920. [PMID: 38440993] - Dandan Song, Rong Wen, Kuai Chen, Fanglin Wen, Dan Xing, Zhibing Wu. Application of thifluzamide to stem rot in peppers: Infection and control mechanisms of sclerotium rolfsii.
Pesticide biochemistry and physiology.
2024 Mar; 200(?):105846. doi:
10.1016/j.pestbp.2024.105846. [PMID: 38582578] - Monika, Chander, Deepansh Sharma, Pawan K Sharma, Sita Ram. Synthesis and biological evaluation of novel benzenesulfonamide incorporated thiazole-triazole hybrids as antimicrobial and antioxidant agents.
Archiv der Pharmazie.
2024 Mar; 357(3):e2300650. doi:
10.1002/ardp.202300650. [PMID: 38154111] - Sepehr Dehghani-Ghahnaviyeh, Cihan Soylu, Pascal Furet, Camilo Velez-Vega. Dissecting the Interaction Fingerprints and Binding Affinity of BYL719 Analogs Targeting PI3Kα.
The journal of physical chemistry. B.
2024 Feb; 128(8):1819-1829. doi:
10.1021/acs.jpcb.3c06766. [PMID: 38373112] - Aizhen Wang, Yanjian Wan, Wei Qi, Gaga Mahai, Xi Qian, Tongzhang Zheng, Yuanyuan Li, Shunqing Xu, Han Xiao, Wei Xia. Urinary biomarkers of exposure to organophosphate, pyrethroid, neonicotinoid insecticides and oxidative stress: A repeated measurement analysis among pregnant women.
The Science of the total environment.
2024 Feb; 912(?):169565. doi:
10.1016/j.scitotenv.2023.169565. [PMID: 38145670] - Li Li, Shijie Yin, Shanshan Kang, Zenglong Chen, Fuyun Wang, Wei Pan. Comprehensive effects of thiamethoxam from contaminated soil on lettuce growth and metabolism.
Environmental pollution (Barking, Essex : 1987).
2024 Feb; 343(?):123186. doi:
10.1016/j.envpol.2023.123186. [PMID: 38142029] - Aroosa Khurshid, Rehan Inayat, Abdul Basit, Syed Husne Mobarak, Shun-Hua Gui, Tong-Xian Liu. Effects of Thiamethoxam on Physiological and Molecular Responses to Potato Plant (Solanum tuberosum), Green Peach Aphid (Myzus persicae) and Parasitoid (Aphidius gifuensis).
Pest management science.
2024 Feb; ?(?):. doi:
10.1002/ps.8006. [PMID: 38312101] - Aleksandra Zimińska, Izabela Lipska, Joanna Gajewska, Anna Draszanowska, Manuel Simões, Magdalena A Olszewska. Antibacterial and Antibiofilm Effects of Photodynamic Treatment with Curcuma L. and Trans-Cinnamaldehyde against Listeria monocytogenes.
Molecules (Basel, Switzerland).
2024 Feb; 29(3):. doi:
10.3390/molecules29030685. [PMID: 38338429] - Shuai Yang, Jiahong Tang, Hongxiang Peng, Chunmei Pu, Shuting Fan, Chen Zhao, Hanhong Xu. Discovery of novel thiazolyl anthranilic diamide derivatives as insecticidal candidates.
Pest management science.
2023 Dec; 79(12):5260-5269. doi:
10.1002/ps.7734. [PMID: 37599274] - Jinyu Hu, Buli Fu, Jinjin Liang, Rong Zhang, Xuegao Wei, Jing Yang, Qimei Tan, Hu Xue, Peipan Gong, Shaonan Liu, Mingjiao Huang, Tianhua Du, Cheng Yin, Chao He, Yao Ji, Chao Wang, Chengjia Zhang, He Du, Qi Su, Xin Yang, Youjun Zhang. CYP4CS5-mediated thiamethoxam and clothianidin resistance is accompanied by fitness cost in the whitefly Bemisia tabaci.
Pest management science.
2023 Oct; ?(?):. doi:
10.1002/ps.7826. [PMID: 37822143] - Hongqin Yang, Lian Xia, Jia Zheng, Zhengmin Xie, Jianli Zhou, Yuangen Wu. Screening and identification of a DNA aptamer to construct the label-free fluorescent aptasensor for ultrasensitive and selective detection of clothianidin residue in agricultural products.
Talanta.
2023 Sep; 262(?):124712. doi:
10.1016/j.talanta.2023.124712. [PMID: 37244242] - Meng Li, Weiwei Wang, Xiang Cheng, Yunxiao Wang, Yao Chen, Jiexiu Gong, Xihao Chang, Xianhai Lv. Design, Synthesis, and Evaluation of Antifungal Bioactivity of Novel Pyrazole Carboxamide Thiazole Derivatives as SDH Inhibitors.
Journal of agricultural and food chemistry.
2023 Aug; 71(30):11365-11372. doi:
10.1021/acs.jafc.3c02671. [PMID: 37463492] - Nannan Xi, Xinghui Xia, Yang Li. Climate warming inhibits neonicotinoid photodegradation on vegetable leaves: Important role of the olefin group in leaf wax.
The Science of the total environment.
2023 Jul; 882(?):163399. doi:
10.1016/j.scitotenv.2023.163399. [PMID: 37061057] - Rui Ma, Na Song, Lveli Wang, Xi Gu, Feng Xiong, Shuqun Zhang, Jie Zhang, Weimin Yang, Zhili Zuo. Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation.
Journal of molecular graphics & modelling.
2023 Jul; 124(?):108567. doi:
10.1016/j.jmgm.2023.108567. [PMID: 37481883] - Nadia A A Elkanzi, Aryam Khaled Ghayad Al-Hazmi, Rania B Bakr, Mohamed A Gad, Hany M Abd El-Lateef, Ali M Ali. Design and Synthesis of Pyridine and Thiazole Derivatives as Eco-friendly Insecticidal to Control Olive Pests.
Chemistry & biodiversity.
2023 Jul; 20(7):e202300559. doi:
10.1002/cbdv.202300559. [PMID: 37340700] - Andrew R Burns, Rachel J Baker, Megan Kitner, Jessica Knox, Brittany Cooke, Jonathan R Volpatti, Aditya S Vaidya, Emily Puumala, Bruna M Palmeira, Elizabeth M Redman, Jamie Snider, Sagar Marwah, Sai W Chung, Margaret H MacDonald, Jens Tiefenbach, Chun Hu, Qi Xiao, Constance A M Finney, Henry M Krause, Sonya A MacParland, Igor Stagljar, John S Gilleard, Leah E Cowen, Susan L F Meyer, Sean R Cutler, James J Dowling, Mark Lautens, Inga Zasada, Peter J Roy. Selective control of parasitic nematodes using bioactivated nematicides.
Nature.
2023 Jun; 618(7963):102-109. doi:
10.1038/s41586-023-06105-5. [PMID: 37225985] - Michael C Cavallaro, Michelle L Hladik, Samantha Hittson, Greg Middleton, W Wyatt Hoback. Comparative toxicity of two neonicotinoid insecticides at environmentally relevant concentrations to telecoprid dung beetles.
Scientific reports.
2023 05; 13(1):8537. doi:
10.1038/s41598-023-35262-w. [PMID: 37237012] - Bibek Aryal, Jian Xia, Zehan Hu, Michael Stumpe, Tashi Tsering, Jie Liu, John Huynh, Yoichiro Fukao, Nina Glöckner, Hsin-Yao Huang, Gloria Sáncho-Andrés, Konrad Pakula, Joerg Ziegler, Karin Gorzolka, Marta Zwiewka, Tomasz Nodzynski, Klaus Harter, Clara Sánchez-Rodríguez, Michał Jasiński, Sabine Rosahl, Markus M Geisler. An LRR receptor kinase controls ABC transporter substrate preferences during plant growth-defense decisions.
Current biology : CB.
2023 Apr; ?(?):. doi:
10.1016/j.cub.2023.04.029. [PMID: 37146609] - Kristen Van Gelder, Edmar R Oliveira-Filho, Jorge Donato García-García, You Hu, Steven D Bruner, Andrew D Hanson. Directed Evolution of Aerotolerance in Sulfide-Dependent Thiazole Synthases.
ACS synthetic biology.
2023 04; 12(4):963-970. doi:
10.1021/acssynbio.2c00512. [PMID: 36920242] - Fang Liu, Xiao Cao, Li Xing, Bangcan He, Nian Zhang, Wei Zeng, Hui Xin, Wei Xue. Design, Synthesis, Biological Activity Evaluation and Action Mechanism of Myricetin Derivatives Containing Thiazolebisamide.
Chemistry & biodiversity.
2023 Mar; 20(3):e202201103. doi:
10.1002/cbdv.202201103. [PMID: 36683342] - Min He, Yuan-Jing Li, Jiang Shao, Ya-Sheng Li, Zi-Ning Cui. Synthesis and biological evaluation of 2,5-disubstituted furan derivatives containing 1,3-thiazole moiety as potential α-glucosidase inhibitors.
Bioorganic & medicinal chemistry letters.
2023 03; 83(?):129173. doi:
10.1016/j.bmcl.2023.129173. [PMID: 36764471] - Aeyaz Ahmad Bhat, Iqubal Singh, Nitin Tandon, Runjhun Tandon. Structure activity relationship (SAR) and anticancer activity of pyrrolidine derivatives: Recent developments and future prospects (A review).
European journal of medicinal chemistry.
2023 Jan; 246(?):114954. doi:
10.1016/j.ejmech.2022.114954. [PMID: 36481599] - Itaru Miura, Sho Horikoshi, Mizue Ichinose, Yuhei Suzuki, Kenya Watanabe. Lurasidone for the Treatment of Schizophrenia: Design, Development, and Place in Therapy.
Drug design, development and therapy.
2023; 17(?):3023-3031. doi:
10.2147/dddt.s366769. [PMID: 37789971] - Jin-Chuang Ru, Xue-Li Zhao, Zhi-Han Cao, Cheng-Zhuang Chen, Ping Li, Zhi-Hua Li. Acute Toxicity of a Novel anti-fouling Material Additive DCOIT to Marine Chlorella sp.
Bulletin of environmental contamination and toxicology.
2022 Dec; 109(6):1018-1022. doi:
10.1007/s00128-022-03623-2. [PMID: 36318303] - Fang Wang, Longfeng Wei, Meiting Guo, Wansheng Yang, Zhu Li, Deyu Hu, Ping Lu. Insights of microbial community evolution under benzisothiazolinone exposure in different soil environments.
Chemosphere.
2022 Nov; 307(Pt 2):135868. doi:
10.1016/j.chemosphere.2022.135868. [PMID: 35932925] - Delong Wang, Min Li, Chunxia Yuan, Yali Fang, Zhijia Zhang. Guaiacol as a natural melanin biosynthesis inhibitor to control northern corn leaf blight.
Pest management science.
2022 Nov; 78(11):4557-4568. doi:
10.1002/ps.7075. [PMID: 35833811] - Huiqi Yeo, Dimitrios P Balagiannis, Jean H Koek, Jane K Parker. Comparison of Odorants in Beef and Chicken Broth-Focus on Thiazoles and Thiazolines.
Molecules (Basel, Switzerland).
2022 Oct; 27(19):. doi:
10.3390/molecules27196712. [PMID: 36235248] - Fajun Tian, Chengkui Qiao, Caixia Wang, Tao Pang, Linlin Guo, Jun Li, Rongli Pang, Hui Liu, Hanzhong Xie. Comparison of the effectiveness of thiamethoxam and its main metabolite clothianidin after foliar spraying and root irrigation to control Myzus persicae on peach.
Scientific reports.
2022 10; 12(1):16883. doi:
10.1038/s41598-022-20659-w. [PMID: 36207356] - Shuang Guan, Ranran Zhang, Yanan Zhao, Zhuoqun Meng, Jing Lu. 1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Environmental toxicology.
2022 Oct; 37(10):2515-2528. doi:
10.1002/tox.23615. [PMID: 35870111] - Elena Jimenez Negro, Jandirk Sendker, Timo Stark, Bartosz Lipowicz, Andreas Hensel. Phytochemical and functional analysis of horseradish (Armoracia rusticana) fermented and non-fermented root extracts.
Fitoterapia.
2022 Oct; 162(?):105282. doi:
10.1016/j.fitote.2022.105282. [PMID: 35988845] - Beatriz Val-Torregrosa, Mireia Bundó, Mani Deepika Mallavarapu, Tzyy-Jen Chiou, Victor Flors, Blanca San Segundo. Loss-of-function of NITROGEN LIMITATION ADAPTATION confers disease resistance in Arabidopsis by modulating hormone signaling and camalexin content.
Plant science : an international journal of experimental plant biology.
2022 Oct; 323(?):111374. doi:
10.1016/j.plantsci.2022.111374. [PMID: 35839945] - Li Li, Hongwu Liang, Tingting Zhao, Yu Liu, Sen Yan, Wentao Zhu. Differential effects of thiamethoxam and clothianidin exposure on their tissue distribution and chronic toxicity in mice.
Chemico-biological interactions.
2022 Oct; 366(?):110149. doi:
10.1016/j.cbi.2022.110149. [PMID: 36084723] - Zhao Li, Kaikai Mao, Ruoheng Jin, Tingwei Cai, Yao Qin, Yunhua Zhang, Shun He, Kangsheng Ma, Hu Wan, Xuexiang Ren, Jianhong Li. miRNA novel_268 targeting NlABCG3 is involved in nitenpyram and clothianidin resistance in Nilaparvata lugens.
International journal of biological macromolecules.
2022 Sep; 217(?):615-623. doi:
10.1016/j.ijbiomac.2022.07.096. [PMID: 35853504] - Miao Li, Qian Lu, Yangping Zhu, Xue Fan, Wen Zhao, Luyong Zhang, Zhenzhou Jiang, Qinwei Yu. Fatostatin inhibits SREBP2-mediated cholesterol uptake via LDLR against selective estrogen receptor α modulator-induced hepatic lipid accumulation.
Chemico-biological interactions.
2022 Sep; 365(?):110091. doi:
10.1016/j.cbi.2022.110091. [PMID: 35944649] - Ying Zhang, Xiaohu Wu, Caijun Chen, Jun Xu, Fengshou Dong, Xingang Liu, Xiaogang Li, Yongquan Zheng. Application of thifluzamide alters microbial network structure and affects methane cycle genes in rice-paddy soil.
The Science of the total environment.
2022 Sep; 838(Pt 1):155769. doi:
10.1016/j.scitotenv.2022.155769. [PMID: 35526624] - Zirui Chen, Xing Sun, Xiaolong Chen, Donglan Wang, Xiangyang Yu, Wenqi Jiang. HPLC-MS/MS analysis of zinc-thiazole residues in foods of plant origin by a modified derivatization-QueChERS method.
Food chemistry.
2022 Aug; 386(?):132752. doi:
10.1016/j.foodchem.2022.132752. [PMID: 35339087] - Muhan Ding, Nan Wu, Qiao Lin, Ya Yan, Yehui Yang, Guangmin Tian, Lian An, Xiaoping Bao. Discovery of Novel Quinazoline-2-Aminothiazole Hybrids Containing a 4-Piperidinylamide Linker as Potential Fungicides against the Phytopathogenic Fungus Rhizoctonia solani.
Journal of agricultural and food chemistry.
2022 Aug; 70(33):10100-10110. doi:
10.1021/acs.jafc.1c07706. [PMID: 35960511] - Sandra S Jovičić Milić, Verica V Jevtić, Snežana R Radisavljević, Biljana V Petrović, Ivana D Radojević, Ivana R Raković, Đorđe S Petrović, Danijela Lj Stojković, Milena Jurišević, Nevena Gajović, Anđela Petrović, Nebojša Arsenijević, Ivan Jovanović, Olivera R Klisurić, Nenad L Vuković, Milena Vukić, Miroslava Kačániová. Synthesis, characterization, DNA interactions and biological activity of new palladium(II) complexes with some derivatives of 2-aminothiazoles.
Journal of inorganic biochemistry.
2022 08; 233(?):111857. doi:
10.1016/j.jinorgbio.2022.111857. [PMID: 35597043] - Marcus G Tan, Whan B Kim, Christine E Jo, Karina Nabieva, Carly Kirshen, Arisa E Ortiz. Topical treatment for postinflammatory hyperpigmentation: a systematic review.
The Journal of dermatological treatment.
2022 Aug; 33(5):2518-2526. doi:
10.1080/09546634.2021.1981814. [PMID: 34525885] - Dimitri Bréard, Thibault Barrit, Daniel Sochard, Sophie Aligon, Elisabeth Planchet, Béatrice Teulat, Josiane Le Corff, Claire Campion, David Guilet. Development of a quantification method for routine analysis of glucosinolates and camalexin in brassicaceous small-sized samples by simultaneous extraction prior to liquid chromatography determination.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2022 Aug; 1205(?):123348. doi:
10.1016/j.jchromb.2022.123348. [PMID: 35777257] - Kevin L Cox. Stronger together: Ethylene, jasmonic acid, and MAPK signaling pathways synergistically induce camalexin synthesis for plant disease resistance.
The Plant cell.
2022 07; 34(8):2829-2830. doi:
10.1093/plcell/koac155. [PMID: 35652267] - Duygu Aydin, Burcu Yuksel. Lessening the toxic effect of the methylisothiazolinone via vermicompost tea on Pisum sativum.
Environmental science and pollution research international.
2022 Jul; 29(33):50443-50453. doi:
10.1007/s11356-022-19396-4. [PMID: 35233668] - Demet Dogan, Gokhan Nur, Haci Ahmet Deveci. Tissue-specific toxicity of clothianidin on rainbow trout (Oncorhynchus mykiss).
Drug and chemical toxicology.
2022 Jul; 45(4):1851-1861. doi:
10.1080/01480545.2021.1892128. [PMID: 33641563] - Iris Lim, Russ Chess-Williams. Mirabegron attenuates porcine ureteral contractility via α1-adrenoceptor antagonism.
Naunyn-Schmiedeberg's archives of pharmacology.
2022 07; 395(7):839-847. doi:
10.1007/s00210-022-02244-0. [PMID: 35445849] - Leticia Gil de Biedma-Elduayen, Pablo Giménez-Gómez, Nuria Morales-Puerto, Rebeca Vidal, Carlos Núñez-de la Calle, María Dolores Gutiérrez-López, Esther O'Shea, María Isabel Colado. Influx of kynurenine into the brain is involved in the reduction of ethanol consumption induced by Ro 61-8048 after chronic intermittent ethanol in mice.
British journal of pharmacology.
2022 07; 179(14):3711-3726. doi:
10.1111/bph.15825. [PMID: 35189673] - Jing Ding, Yan Zhang, Shanqi Wan, Liu Yang, Xiaohua Cui, Caiping Zhao, Suo Zhang, Zhuocheng Meng. A novel and robust analytical method for the quantification of perospirone in human plasma using an LC-MS/MS system with self-internal standard calibration.
Clinical biochemistry.
2022 Jul; 105-106(?):49-56. doi:
10.1016/j.clinbiochem.2022.04.006. [PMID: 35436467] - Chunni Zhang, Shaokai Du, Ruifang Liu, Wu Dai. Overexpression of Multiple Cytochrome P450 Genes Conferring Clothianidin Resistance in Bradysia odoriphaga.
Journal of agricultural and food chemistry.
2022 Jun; 70(25):7636-7643. doi:
10.1021/acs.jafc.2c01315. [PMID: 35709533] - Qinhong Jiang, Min Peng, Meizhen Yin, Jie Shen, Shuo Yan. Nanocarrier-Loaded Imidaclothiz Promotes Plant Uptake and Decreases Pesticide Residue.
International journal of molecular sciences.
2022 Jun; 23(12):. doi:
10.3390/ijms23126651. [PMID: 35743094] - Xiangfeng Yao, Yu Liu, Xiang Liu, Zhihua Qiao, Shiang Sun, Xiangdong Li, Jun Wang, Fengwen Zhang, Xingyin Jiang. Effects of thifluzamide on soil fungal microbial ecology.
Journal of hazardous materials.
2022 06; 431(?):128626. doi:
10.1016/j.jhazmat.2022.128626. [PMID: 35278970] - Ngoc Huu Nguyen, Patricia Trotel-Aziz, Sandra Villaume, Fanja Rabenoelina, Christophe Clément, Fabienne Baillieul, Aziz Aziz. Priming of camalexin accumulation in induced systemic resistance by beneficial bacteria against Botrytis cinerea and Pseudomonas syringae pv. tomato DC3000.
Journal of experimental botany.
2022 06; 73(11):3743-3757. doi:
10.1093/jxb/erac070. [PMID: 35191984] - Pablo Morón-Elorza, Carlos Rojo-Solís, Teresa Álvaro-Álvarez, Mónica Valls-Torres, Daniel García-Párraga, Teresa Encinas. PHARMACOKINETICS OF MELOXICAM AFTER A SINGLE 1.5 MG/KG INTRAMUSCULAR ADMINISTRATION TO NURSEHOUND SHARKS (SCYLIORHINUS STELLARIS) AND ITS EFFECTS ON HEMATOLOGY AND PLASMA BIOCHEMISTRY.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2022 Jun; 53(2):393-401. doi:
10.1638/2021-0144. [PMID: 35758581] - Jing Wu, Bo Feng, Li-Xin Gao, Chun Zhang, Jia Li, Da-Jun Xiang, Yi Zang, Wen-Long Wang. Synthesis and Biochemical Evaluation of 8H-Indeno[1,2-d]thiazole Derivatives as Novel SARS-CoV-2 3CL Protease Inhibitors.
Molecules (Basel, Switzerland).
2022 May; 27(10):. doi:
10.3390/molecules27103359. [PMID: 35630836] - J F Jiang, W L Song, Y P Liu, J P Liu, M Wang. [Study on determination of 2-thioxothiazolidine-4-carboxylic Acid in urine by high performance liquid chromatography].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2022 May; 40(5):370-373. doi:
10.3760/cma.j.cn121094-20210129-00061. [PMID: 35680582] - Ivan V Smolyaninov, Daria A Burmistrova, Maxim V Arsenyev, Maria A Polovinkina, Nadezhda P Pomortseva, Georgy K Fukin, Andrey I Poddel'sky, Nadezhda T Berberova. Synthesis and Antioxidant Activity of New Catechol Thioethers with the Methylene Linker.
Molecules (Basel, Switzerland).
2022 May; 27(10):. doi:
10.3390/molecules27103169. [PMID: 35630646] - Giovambattista Desideri, Marek Rajzer, Martijn Gerritsen, Michael T Nurmohamed, Cristina Giannattasio, Anne-Kathrin Tausche, Claudio Borghi. Effects of intensive urate lowering therapy with febuxostat in comparison with allopurinol on pulse wave velocity in patients with gout and increased cardiovascular risk: the FORWARD study.
European heart journal. Cardiovascular pharmacotherapy.
2022 05; 8(3):236-242. doi:
10.1093/ehjcvp/pvaa144. [PMID: 33410912] - Ngoc Huu Nguyen, Patricia Trotel-Aziz, Christophe Clément, Philippe Jeandet, Fabienne Baillieul, Aziz Aziz. Camalexin accumulation as a component of plant immunity during interactions with pathogens and beneficial microbes.
Planta.
2022 May; 255(6):116. doi:
10.1007/s00425-022-03907-1. [PMID: 35511374] - Thomas Halverson, Elizabeth R Mueller, Linda Brubaker, Alan J Wolfe. Symptom improvement with mirabegron treatment is associated with urobiome changes in adult women.
International urogynecology journal.
2022 05; 33(5):1319-1328. doi:
10.1007/s00192-022-05190-w. [PMID: 35412069] - Ru Huang, Alexander Tamalunas, Raphaela Waidelich, Frank Strittmatter, Christian G Stief, Martin Hennenberg. Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions.
The Journal of pharmacology and experimental therapeutics.
2022 05; 381(2):176-187. doi:
10.1124/jpet.121.001029. [PMID: 35153197] - Ophelia Yin, Tarundeep Kakkar, Anil Duggal, Masakatsu Kotsuma, Minggao Shi, Hans Lanz, Michael A Grosso. Edoxaban Exposure in Patients With Atrial Fibrillation and Estimated Creatinine Clearance Exceeding 100 mL/min.
Clinical pharmacology in drug development.
2022 05; 11(5):666-674. doi:
10.1002/cpdd.1050. [PMID: 34877813] - Md Abdur Rashid, Saiqa Muneer, Yahya Alhamhoom, Nazrul Islam. Rapid Assay for the Therapeutic Drug Monitoring of Edoxaban.
Biomolecules.
2022 04; 12(4):. doi:
10.3390/biom12040590. [PMID: 35454179] - Michelle Moughaizel, Elie Dagher, Nora Bouhsina, Valérie Lalanne, Chantal Thorin, Jean-Claude Desfontis, M Yassine Mallem. Effects of chronic mirabegron treatment on metabolic and cardiovascular parameters as well as on atherosclerotic lesions of WHHL rabbits with high-fructose high-fat diet-induced insulin resistance.
European journal of pharmacology.
2022 Apr; 921(?):174870. doi:
10.1016/j.ejphar.2022.174870. [PMID: 35257716] - Anna Riccio, Silvia Santopolo, Antonio Rossi, Sara Piacentini, Jean-Francois Rossignol, M Gabriella Santoro. Impairment of SARS-CoV-2 spike glycoprotein maturation and fusion activity by nitazoxanide: an effect independent of spike variants emergence.
Cellular and molecular life sciences : CMLS.
2022 Apr; 79(5):227. doi:
10.1007/s00018-022-04246-w. [PMID: 35391601] - Weilun Miao, Jiaojiao Shi, Jiayi Huang, Yongpin Lin, Chang Cui, Yue Zhu, Bingyu Zheng, Mingfang Li, Qi Jiang, Minglong Chen. Azoramide ameliorated tachypacing-induced injury of atrial myocytes differentiated from human induced pluripotent stem cell by regulating endoplasmic reticulum stress.
Stem cell research.
2022 04; 60(?):102686. doi:
10.1016/j.scr.2022.102686. [PMID: 35101669] - Shihang Han, Yingying Bi, Lijun Han, Shuangyu Song, Ziyu Ye, Fayi Qin, Xinru Lv. Residue Behavior and Risk Assessment of Pyraclostrobin and Thifluzamide in Cowpea.
Bulletin of environmental contamination and toxicology.
2022 Apr; 108(4):786-790. doi:
10.1007/s00128-021-03421-2. [PMID: 35067727] - Fernanda Ac Pereira, Vitor Sc de Andrade, Elaine A Souza, Marcio Cs de Mattos, Denilson F Oliveira. 2-Aminoselenazoles and 2-aminothiazoles: One-pot synthesis and control of the fungus Colletotrichum lindemuthianum in common beans.
Pest management science.
2022 Apr; 78(4):1665-1676. doi:
10.1002/ps.6786. [PMID: 34994047] - Yanmei Yang, Shu Qin, Xia Wang, Junli Cao, Jindong Li. Dissipation Behavior and Acute Dietary Risk Assessment of Thiamethoxam and Its Metabolite Clothianidin on Spinach.
Molecules (Basel, Switzerland).
2022 Mar; 27(7):. doi:
10.3390/molecules27072209. [PMID: 35408608] - Hiroshi Nakagomi, Takahiko Mitsui, Hiroshi Shimura, Tatsuya Ihara, Satoru Kira, Norifumi Sawada, Masayuki Takeda. Mirabegron for overactive bladder in frail patients 80 years or over (HOKUTO study).
BMC urology.
2022 Mar; 22(1):40. doi:
10.1186/s12894-022-00989-7. [PMID: 35313873] - Ranjana Aggarwal, Mona Hooda, Prince Kumar, Naman Jain, Gyan Prakash Dubey, Heerak Chugh, Ramesh Chandra. Visible-Light-Prompted Synthesis and Binding Studies of 5,6-Dihydroimidazo[2,1-b]thiazoles with BSA and DNA Using Biophysical and Computational Methods.
The Journal of organic chemistry.
2022 03; 87(6):3952-3966. doi:
10.1021/acs.joc.1c02471. [PMID: 35235320] - Tianyang You, Yuan Ding, He Chen, Guangyue Song, Lianrun Huang, Minghua Wang, Xiude Hua. Development of competitive and noncompetitive immunoassays for clothianidin with high sensitivity and specificity using phage-displayed peptides.
Journal of hazardous materials.
2022 03; 425(?):128011. doi:
10.1016/j.jhazmat.2021.128011. [PMID: 34896720] - Ancai Liao, Lin Li, Tienan Wang, Aidang Lu, Ziwen Wang, Qingmin Wang. Discovery of Phytoalexin Camalexin and Its Derivatives as Novel Antiviral and Antiphytopathogenic-Fungus Agents.
Journal of agricultural and food chemistry.
2022 Mar; 70(8):2554-2563. doi:
10.1021/acs.jafc.1c07805. [PMID: 35179026] - Shuhe Ma, Kosaku Murakami, Kazune Tanaka, Motomu Hashimoto, Masao Tanaka, Koji Kitagori, Shuji Akizuki, Ran Nakashima, Hajime Yoshifuji, Koichiro Ohmura, Akio Morinobu, Tsuneyo Mimori. Fatostatin ameliorates inflammation without affecting cell viability.
FEBS open bio.
2022 03; 12(3):594-604. doi:
10.1002/2211-5463.13364. [PMID: 35015380] - Lauren P Kane, Matthew R O'Connor, Mark G Papich. PHARMACOKINETICS OF A SINGLE DOSE OF INTRAMUSCULAR AND ORAL MELOXICAM IN YELLOW STINGRAYS (UROBATIS JAMAICENSIS).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2022 Mar; 53(1):153-158. doi:
10.1638/2021-0123. [PMID: 35339160] - Hannah M Ficarino, Michael Z Caposole, S Noelle Davis, Mackenzie N Krebsbach, Emily F McGowin, Kaitlin M Alexander, Christopher M Kinnard, Jon D Simmons. Neuroleptic Malignant Syndrome: A Potential Etiology of Multisystem Organ Failure in a Burn Patient.
The American surgeon.
2022 Mar; 88(3):519-520. doi:
10.1177/0003134820945245. [PMID: 32988244] - Lixin Fang, Koji Ohashi, Hayato Ogawa, Naoya Otaka, Hiroshi Kawanishi, Tomonobu Takikawa, Yuta Ozaki, Kunihiko Takahara, Minako Tatsumi, Mikito Takefuji, Toyoaki Murohara, Noriyuki Ouchi. Factor Xa inhibitor, edoxaban ameliorates renal injury after subtotal nephrectomy by reducing epithelial-mesenchymal transition and inflammatory response.
Physiological reports.
2022 03; 10(5):e15218. doi:
10.14814/phy2.15218. [PMID: 35262272] - Tetsuro Yoshida, Akihiro Nakamura, Junichi Funada, Mari Amino, Wataru Shimizu, Masayuki Fukuzawa, Saori Watanabe, Takuya Hayashi, Takeshi Yamashita, Ken Okumura, Masaharu Akao. Efficacy and Safety of Edoxaban 15 mg According to Renal Function in Very Elderly Patients With Atrial Fibrillation: A Subanalysis of the ELDERCARE-AF Trial.
Circulation.
2022 03; 145(9):718-720. doi:
10.1161/circulationaha.121.057190. [PMID: 35226559] - Eamon O Murchu, Susan Spillane, Paula Byrne, Michelle O'Neill, Patricia Harrington, Máirín Ryan. Interventions in an Ambulatory Setting to Prevent Progression to Severe Disease in Patients With COVID-19: A Systematic Review.
The Annals of pharmacotherapy.
2022 03; 56(3):309-318. doi:
10.1177/10600280211028242. [PMID: 34157890] - Lauren E Walker, Richard FitzGerald, Geoffrey Saunders, Rebecca Lyon, Michael Fisher, Karen Martin, Izabela Eberhart, Christie Woods, Sean Ewings, Colin Hale, Rajith K R Rajoli, Laura Else, Sujan Dilly-Penchala, Alieu Amara, David G Lalloo, Michael Jacobs, Henry Pertinez, Parys Hatchard, Robert Waugh, Megan Lawrence, Lucy Johnson, Keira Fines, Helen Reynolds, Timothy Rowland, Rebecca Crook, Emmanuel Okenyi, Kelly Byrne, Pavel Mozgunov, Thomas Jaki, Saye Khoo, Andrew Owen, Gareth Griffiths, Thomas E Fletcher. An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2.
Clinical pharmacology and therapeutics.
2022 03; 111(3):585-594. doi:
10.1002/cpt.2463. [PMID: 34699618] - Can Zhao, Yuting Li, Zhijian Liang, Lihong Gao, Chenggui Han, Xuehong Wu. Molecular Mechanisms Associated with the Resistance of Rhizoctonia solani AG-4 Isolates to the Succinate Dehydrogenase Inhibitor Thifluzamide.
Phytopathology.
2022 Mar; 112(3):567-578. doi:
10.1094/phyto-06-21-0266-r. [PMID: 34615378] - Weixiong Chen, Bo Feng, Sheng Han, Peipei Wang, Wuhong Chen, Yi Zang, Jia Li, Youhong Hu. Discovery of highly potent SARS-CoV-2 Mpro inhibitors based on benzoisothiazolone scaffold.
Bioorganic & medicinal chemistry letters.
2022 02; 58(?):128526. doi:
10.1016/j.bmcl.2022.128526. [PMID: 34998903] - Christoph Suppan, Ricarda Graf, Stephan Jahn, Qing Zhou, Eva Valentina Klocker, Rupert Bartsch, Angelika Terbuch, Karl Kashofer, Peter Regitnig, Joerg Lindenmann, Florian Posch, Hanno Gerritsmann, Philipp J Jost, Ellen Heitzer, Nadia Dandachi, Marija Balic. Sensitive and robust liquid biopsy-based detection of PIK3CA mutations in hormone-receptor-positive metastatic breast cancer patients.
British journal of cancer.
2022 02; 126(3):456-463. doi:
10.1038/s41416-021-01601-9. [PMID: 34754095] - Xueju Qi, Shuna Zhang, Zekun Chen, Lijun Wang, Wenyong Zhu, Chuanjin Yin, Junting Fan, Xiaochen Wu, Jing Wang, Chuanlong Guo. EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway.
Chemico-biological interactions.
2022 Jan; 352(?):109773. doi:
10.1016/j.cbi.2021.109773. [PMID: 34902296] - Tetsuji Shinohara, Naohiko Takahashi, Yasushi Mukai, Tetsuya Kimura, Keita Yamaguchi, Atsushi Takita, Hideki Origasa, Ken Okumura. Catheter Ablation Energy Sources and Myocardial Injury and Coagulation Biomarkers During Uninterrupted Periprocedural Edoxaban Use - A Subanalysis of KYU-RABLE.
Circulation journal : official journal of the Japanese Circulation Society.
2022 01; 86(2):280-286. doi:
10.1253/circj.cj-21-0247. [PMID: 34275977] - Kai-Long Li, Wu-Ying Chen, Min Zhang, Xiang-Wen Luo, Yong Liu, De-Yong Zhang, Ang Chen. Monitoring residue levels and dietary risk assessment of thiamethoxam and its metabolite clothianidin for Chinese consumption of Chinese kale.
Journal of the science of food and agriculture.
2022 Jan; 102(1):417-424. doi:
10.1002/jsfa.11371. [PMID: 34143904] - Sraa Abu-Melha, Mastoura Mohamed Edrees, Musa A Said, Sayed M Riyadh, Nadia S Al-Kaff, Sobhi M Gomha. Potential COVID-19 Drug Candidates Based on Diazinyl-Thiazol-Imine Moieties: Synthesis and Greener Pastures Biological Study.
Molecules (Basel, Switzerland).
2022 Jan; 27(2):. doi:
10.3390/molecules27020488. [PMID: 35056802] - Yihao Li, Kun Liu, Ganlu Tong, Chao Xi, Jin Liu, Heping Zhao, Yingdian Wang, Dongtao Ren, Shengcheng Han. MPK3/MPK6-mediated phosphorylation of ERF72 positively regulates resistance to Botrytis cinerea through directly and indirectly activating the transcription of camalexin biosynthesis enzymes.
Journal of experimental botany.
2022 01; 73(1):413-428. doi:
10.1093/jxb/erab415. [PMID: 34499162] - Karolina M Czajka, Kabwe Nkongolo. Transcriptome analysis of trembling aspen (Populus tremuloides) under nickel stress.
PloS one.
2022; 17(10):e0274740. doi:
10.1371/journal.pone.0274740. [PMID: 36227867] - Kong Y Chen, Robert J Brychta, Nikita S Israni, Alex Jiang, Hannah J Lea, Taylor N Lentz, Anne E Pierce, Aaron M Cypess. Activating Human Adipose Tissue with the β3-Adrenergic Agonist Mirabegron.
Methods in molecular biology (Clifton, N.J.).
2022; 2448(?):83-96. doi:
10.1007/978-1-0716-2087-8_5. [PMID: 35167091] - Lon V Kendall, Alexandrea L Bailey, Benjamin Singh, Whitney McGee. Toxic Effects of High-dose Meloxicam and Carprofen on Female CD1 Mice.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2022 01; 61(1):75-80. doi:
10.30802/aalas-jaalas-21-000071. [PMID: 34920791] - Xi He, Wenjun Hu, Fanhua Meng, Xingzhou Li. Design, Synthesis, and Pharmacokinetic Evaluation of O-Carbamoyl Tizoxanide Prodrugs.
Medicinal chemistry (Shariqah (United Arab Emirates)).
2022; 18(1):140-150. doi:
10.2174/1573406416666201120102905. [PMID: 33222677]