m-Aminobenzoic acid (BioDeep_00000018403)

   

human metabolite blood metabolite


代谢物信息卡片


3-Aminobenzoic acid, monosodium salt

化学式: C7H7NO2 (137.0477)
中文名称: 间氨基苯甲酸, 3-氨基苯甲酸
谱图信息: 最多检出来源 Homo sapiens(urine) 3.73%

分子结构信息

SMILES: C1=CC(=CC(=C1)N)C(=O)O
InChI: InChI=1S/C7H7NO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H,9,10)

描述信息

m-Aminobenzoic acid (also known as 3-aminobenzoic acid or MABA) is an organic compound with the molecular formula H2NC6H4CO2H. MABA is a white solid, although commercial samples are often colored. It is only slightly soluble in water. It is soluble in acetone, boiling water, hot alcohol, hot chloroform and ether. It consists of a benzene ring substituted with an amino group and a carboxylic acid. m-Aminobenzoic acid belongs to the class of organic compounds known as aminobenzoic acids. These are benzoic acids containing an amine group attached to the benzene moiety. Outside of the human body, m-Aminobenzoic acid has been detected, but not quantified in cow milk. This could make m-aminobenzoic acid a potential biomarker for the consumption of these foods.
m-Aminobenzoic acid is an inactive analog of 3-aminobenzamide, a known modulator of PARP activity, inhibitor of poly ADP-ribose and of the PARP-specific protease (interleukin-1 beta converting enzyme (ICE)-like protease). (PMID 8657188)

同义名列表

18 个代谢物同义名

3-Aminobenzoic acid, monosodium salt; Aniline-3-carboxylic acid; Meta-aminobenzoic acid; Aniline-3-carboxylate; m-Amonibenzoic acid; m-Aminobenzoic acid; 3-AMINOBENZOIC ACID; 3-Aminobenzoesaeure; m-Aminobenzoesaeure; 3-Carboxyaniline; m-Carboxyaniline; m-Aminobenzoate; 3-Aminobenzoate; m-Amonibenzoate; gabaculine; MABA; m-Aminobenzoic acid; 3-Aminobenzoic acid



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Maryia M Nudnova, Jérôme Sigg, Pascal Wallimann, Renato Zenobi. Plasma ionization source for atmospheric pressure mass spectrometry imaging using near-field optical laser ablation. Analytical chemistry. 2015 Jan; 87(2):1323-9. doi: 10.1021/ac504039w. [PMID: 25517927]
  • Bahiru P Benke, Nandita Madhavan. Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine. Chemical communications (Cambridge, England). 2013 Aug; 49(66):7340-2. doi: 10.1039/c3cc44224a. [PMID: 23851602]
  • Olaf Czarnecki, Christine Gläßer, Jin-Gui Chen, Klaus F X Mayer, Bernhard Grimm. Evidence for a Contribution of ALA Synthesis to Plastid-To-Nucleus Signaling. Frontiers in plant science. 2012; 3(?):236. doi: 10.3389/fpls.2012.00236. [PMID: 23112801]
  • N Ferradini, A Nicolia, S Capomaccio, F Veronesi, D Rosellini. A point mutation in the Medicago sativa GSA gene provides a novel, efficient, selectable marker for plant genetic engineering. Journal of biotechnology. 2011 Nov; 156(2):147-52. doi: 10.1016/j.jbiotec.2011.08.015. [PMID: 21875626]
  • Emilia Balsemão-Pires, Yvon Jaillais, Bradley J S C Olson, Leonardo R Andrade, James G Umen, Joanne Chory, Gilberto Sachetto-Martins. The Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism. BMC plant biology. 2011 Jun; 11(?):108. doi: 10.1186/1471-2229-11-108. [PMID: 21689410]
  • Marion Sander, Maike Petersen. Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, rosmarinic acid synthase and hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl-transferase, from Coleus blumei Benth. Planta. 2011 Jun; 233(6):1157-71. doi: 10.1007/s00425-011-1367-2. [PMID: 21318289]
  • Yuan-Ping Pang, Jewn Giew Park, Shaohua Wang, Anuradha Vummenthala, Rajesh K Mishra, John E McLaughlin, Rong Di, Jennifer Nielsen Kahn, Nilgun E Tumer, Laszlo Janosi, Jon Davis, Charles B Millard. Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach. PloS one. 2011 Mar; 6(3):e17883. doi: 10.1371/journal.pone.0017883. [PMID: 21455295]
  • Fiorenzo Conti, Marcello Melone, Giorgia Fattorini, Luca Bragina, Silvia Ciappelloni. A Role for GAT-1 in Presynaptic GABA Homeostasis?. Frontiers in cellular neuroscience. 2011; 5(?):2. doi: 10.3389/fncel.2011.00002. [PMID: 21503156]
  • Chi-Fang Peng, Zhi-Feng Qin, Zhou-Xi Ruan, Chuan-Lai Xu, Zheng-Yu Jin. Rapid determination of clenbuterol in urine by a competitive bead immunoassay based on Luminex technology. Immunological investigations. 2011; 40(1):14-28. doi: 10.3109/08820139.2010.507687. [PMID: 20809697]
  • Viktor Demko, Andrej Pavlovic, Ján Hudák. Gabaculine alters plastid development and differentially affects abundance of plastid-encoded DPOR and nuclear-encoded GluTR and FLU-like proteins in spruce cotyledons. Journal of plant physiology. 2010 Jun; 167(9):693-700. doi: 10.1016/j.jplph.2009.12.008. [PMID: 20129699]
  • László Héja, Péter Barabás, Gabriella Nyitrai, Katalin A Kékesi, Bálint Lasztóczi, Orsolya Toke, Gábor Tárkányi, Karsten Madsen, Arne Schousboe, Arpád Dobolyi, Miklós Palkovits, Julianna Kardos. Glutamate uptake triggers transporter-mediated GABA release from astrocytes. PloS one. 2009 Sep; 4(9):e7153. doi: 10.1371/journal.pone.0007153. [PMID: 19777062]
  • Daniele Rosellini, Stefano Capomaccio, Nicoletta Ferradini, Maria Luisa Savo Sardaro, Alessandro Nicolia, Fabio Veronesi. Non-antibiotic, efficient selection for alfalfa genetic engineering. Plant cell reports. 2007 Jul; 26(7):1035-44. doi: 10.1007/s00299-007-0321-z. [PMID: 17333020]
  • Chi-Hsiao Yeh, Tzu-Ping Chen, Chieh-Hung Lee, Yi-Chen Wu, Yu-Min Lin, Pyng Jing Lin. Inhibition of poly(adp-ribose) polymerase reduces cardiomyocytic apoptosis after global cardiac arrest under cardiopulmonary bypass. Shock (Augusta, Ga.). 2006 Feb; 25(2):168-75. doi: 10.1097/01.shk.0000188709.04777.48. [PMID: 16525356]
  • Claudia Fiorillo, Vanessa Ponziani, Lara Giannini, Cristina Cecchi, Alessandra Celli, Chiara Nediani, Avio Maria Perna, Piero Liguori, Niccolò Nassi, Lucia Formigli, Alessia Tani, Paolo Nassi. Beneficial effects of poly (ADP-ribose) polymerase inhibition against the reperfusion injury in heart transplantation. Free radical research. 2003 Mar; 37(3):331-9. doi: 10.1080/1071576021000055262. [PMID: 12688429]
  • Ralf Welsch, Joaquin Medina, Giovanni Giuliano, Peter Beyer, Johannes Von Lintig. Structural and functional characterization of the phytoene synthase promoter from Arabidopsis thaliana. Planta. 2003 Jan; 216(3):523-34. doi: 10.1007/s00425-002-0885-3. [PMID: 12520345]
  • Tatsuru Masuda, Jürgen E W Polle, Anastasios Melis. Biosynthesis and distribution of chlorophyll among the photosystems during recovery of the green alga Dunaliella salina from irradiance stress. Plant physiology. 2002 Feb; 128(2):603-14. doi: 10.1104/pp.010595. [PMID: 11842163]
  • K Kakehi, M Kinoshita, D Kawakami, J Tanaka, K Sei, K Endo, Y Oda, M Iwaki, T Masuko. Capillary electrophoresis of sialic acid-containing glycoprotein. Effect of the heterogeneity of carbohydrate chains on glycoform separation using an alpha1-acid glycoprotein as a model. Analytical chemistry. 2001 Jun; 73(11):2640-7. doi: 10.1021/ac001382u. [PMID: 11403311]
  • R Halmosi, Z Berente, E Osz, K Toth, P Literati-Nagy, B Sumegi. Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system. Molecular pharmacology. 2001 Jun; 59(6):1497-505. doi: 10.1124/mol.59.6.1497. [PMID: 11353811]
  • T Saita, H Fujito, M Mori. Determination of topotecan by ELISA. Biological & pharmaceutical bulletin. 2001 Apr; 24(4):321-6. doi: 10.1248/bpb.24.321. [PMID: 11305588]
  • P E Devaraj, M J Clemens, A P Johnstone. Characterization of the superinduction of the c-myc proto-oncogene in fibroblasts by benzamide derivatives. Molecular and cellular biochemistry. 1993 Jul; 124(2):175-81. doi: 10.1007/bf00929210. [PMID: 8232288]
  • . . . . doi: . [PMID: 18419821]