Dimethylamphetamine (BioDeep_00000018379)

 

Secondary id: BioDeep_00000624667

human metabolite Chemicals and Drugs Volatile Flavor Compounds


代谢物信息卡片


Dimethylamphetamine hydrochloride, (+-)-isomer

化学式: C11H17N (163.1360922)
中文名称: 二甲基苯丙胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CC1=CC=CC=C1)N(C)C
InChI: InChI=1S/C11H17N/c1-10(12(2)3)9-11-7-5-4-6-8-11/h4-8,10H,9H2,1-3H3

描述信息

Dimethylamphetamine (Metrotonin), also referred to as dimetamfetamine and N,N-dimethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine chemical classes. Dimethylamphetamine has weaker stimulant effects than amphetamine or methamphetamine and is considerably less addictive and less neurotoxic compared to methamphetamine. However, it still retains some mild stimulant effects and abuse potential, and is a Schedule I controlled drug.
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants

同义名列表

22 个代谢物同义名

Dimethylamphetamine hydrochloride, (+-)-isomer; Dimethylamphetamine hydrochloride, (S)-isomer; (S)-N,N,alpha-Trimethylbenzeneethanamine; alpha-Phenyl-beta-dimethylaminopropane; dimethyl(1-phenylpropan-2-yl)amine; N,N,alpha-Trimethyl-phenethylamine; Dimethylamphetamine hydrochloride; N,N,alpha-Trimethylphenethylamine; Dimethylamphetamine, (+-)-isomer; 1-Phenyl-2-dimethylamino-propan; Dimethylamphetamine, (S)-isomer; 2-Dimethylamino-1-phenylpropane; 1-Phenyl-2-dimethylaminopropane; Dimethylamphetamine, (R)-isomer; N-Methyl-methamphetamine; N,N-Dimethylamphetamine; Dimethylamphetamine; Dimetamfetamine; Dimephenopan; Metrotonin; Perneurin; Dimethylamphetamine



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sang Kyu Lee, So-Hee Kim, Ho Jun Kim, Hye Hyun Yoo, Oh Seung Kwon, Moon Kyo In, Changbae Jin, Dong Hyun Kim, Jaeick Lee. Simultaneous qualitative and quantitative method using liquid chromatography selected reaction monitoring-triggered quantitation-enhanced data-dependent tandem mass spectrometry for the identification and classification of amphetamine-type stimulant abusers in human urine. Rapid communications in mass spectrometry : RCM. 2010 Nov; 24(21):3139-45. doi: 10.1002/rcm.4747. [PMID: 20941760]
  • Jin Young Kim, Jae Chul Cheong, Beom Jun Ko, Sang Kyu Lee, Hye Hyun Yoo, Changbae Jin, Moon Kyo In. Simultaneous determination of methamphetamine, 3,4-methylenedioxy-N-methylamphetamine, 3,4-methylenedioxy-N-ethylamphetamine, N,N-dimethylamphetamine, and their metabolites in urine by liquid chromatography-electrospray ionization-tandem mass spectrometry. Archives of pharmacal research. 2008 Dec; 31(12):1644-51. doi: 10.1007/s12272-001-2163-5. [PMID: 19099236]
  • W D Barker, U Antia. A study of the use of Ephedra in the manufacture of methamphetamine. Forensic science international. 2007 Mar; 166(2-3):102-9. doi: 10.1016/j.forsciint.2006.04.005. [PMID: 16707238]
  • Wing-Chi Cheng, Vincent King-Kuen Mok, Ka-Keung Chan, Ava Fung-Man Li. A rapid and convenient LC/MS method for routine identification of methamphetamine/dimethylamphetamine and their metabolites in urine. Forensic science international. 2007 Feb; 166(1):1-7. doi: 10.1016/j.forsciint.2006.03.011. [PMID: 16621383]
  • Motoyasu Sato, Minemasa Hida, Hisamitsu Nagase. Analysis of dimethylamphetamine and its metabolites in human urine by liquid chromatography-electrospray ionization-mass spectrometry with direct sample injection. Forensic science international. 2002 Aug; 128(3):146-54. doi: 10.1016/s0379-0738(02)00190-1. [PMID: 12175795]
  • N Kato, A Ogamo. A TLC visualisation reagent for dimethylamphetamine and other abused tertiary amines. Science & justice : journal of the Forensic Science Society. 2001 Oct; 41(4):239-44. doi: 10.1016/s1355-0306(01)71907-7. [PMID: 11793881]
  • M Katagi, M Tatsuno, A Miki, M Nishikawa, H Tsuchihashi. Discrimination of dimethylamphetamine and methamphetamine use: simultaneous determination of dimethylamphetamine-N-oxide and other metabolites in urine by high-performance liquid chromatography-electrospray ionization mass spectrometry. Journal of analytical toxicology. 2000 Jul; 24(5):354-8. doi: 10.1093/jat/24.5.354. [PMID: 10926359]
  • R Kikura, Y Nakahara, S Kojima. Simultaneous determination of dimethylamphetamine and its metabolites in rat hair by gas chromatography-mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications. 2000 May; 741(2):163-73. doi: 10.1016/s0378-4347(00)00046-3. [PMID: 10872586]
  • R de la Torre, R Badia, G Gonzàlez, M García, M J Pretel, M Farré, J Segura. Cross-reactivity of stimulants found in sports drug testing by two fluorescence polarization immunoassays. Journal of analytical toxicology. 1996 May; 20(3):165-70. doi: 10.1093/jat/20.3.165. [PMID: 8735197]
  • T Inoue, S Suzuki. The metabolism of dimethylamphetamine in rat and man. Xenobiotica; the fate of foreign compounds in biological systems. 1987 Aug; 17(8):965-71. doi: 10.3109/00498258709044195. [PMID: 3673111]