2-(1-Phenylpentoxycarbonyl)benzoic acid (BioDeep_00000183703)
human metabolite blood metabolite
代谢物信息卡片
2-{[(1-phenylpentyl)oxy]carbonyl}benzoic acid
化学式: C19H20O4 (312.13615200000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCC(C1=CC=CC=C1)OC(=O)C2=CC=CC=C2C(=O)O
InChI: InChI=1S/C19H20O4/c1-2-3-13-17(14-9-5-4-6-10-14)23-19(22)16-12-8-7-11-15(16)18(20)21/h4-12,17H,2-3,13H2,1H3,(H,20,21)
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Allan C Just, Robin M Whyatt, Rachel L Miller, Andrew G Rundle, Qixuan Chen, Antonia M Calafat, Adnan Divjan, Maria J Rosa, Hanjie Zhang, Frederica P Perera, Inge F Goldstein, Matthew S Perzanowski. Children's urinary phthalate metabolites and fractional exhaled nitric oxide in an urban cohort.
American journal of respiratory and critical care medicine.
2012 Nov; 186(9):830-7. doi:
10.1164/rccm.201203-0398oc. [PMID: 22923660] - Allan C Just, Robin M Whyatt, Matthew S Perzanowski, Antonia M Calafat, Frederica P Perera, Inge F Goldstein, Qixuan Chen, Andrew G Rundle, Rachel L Miller. Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort.
Environmental health perspectives.
2012 Oct; 120(10):1475-80. doi:
10.1289/ehp.1104544. [PMID: 22732598] - Robin M Whyatt, Xinhua Liu, Virginia A Rauh, Antonia M Calafat, Allan C Just, Lori Hoepner, Diurka Diaz, James Quinn, Jennifer Adibi, Frederica P Perera, Pam Factor-Litvak. Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age.
Environmental health perspectives.
2012 Feb; 120(2):290-5. doi:
10.1289/ehp.1103705. [PMID: 21893441] - Thomas Göen, Lorenz Dobler, Jan Koschorreck, Johannes Müller, Gerhard Andreas Wiesmüller, Hans Drexler, Marike Kolossa-Gehring. Trends of the internal phthalate exposure of young adults in Germany--follow-up of a retrospective human biomonitoring study.
International journal of hygiene and environmental health.
2011 Dec; 215(1):36-45. doi:
10.1016/j.ijheh.2011.07.011. [PMID: 21889907] - Hanne Frederiksen, Lise Aksglaede, Kaspar Sorensen, Niels E Skakkebaek, Anders Juul, Anna-Maria Andersson. Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: estimation of daily phthalate intake.
Environmental research.
2011 Jul; 111(5):656-63. doi:
10.1016/j.envres.2011.03.005. [PMID: 21429484] - Wen-Ching Chen, Han-Ching Huang, Yei-Shung Wang, Jui-Hung Yen. Effect of benzyl butyl phthalate on physiology and proteome characterization of water celery (Ipomoea aquatica Forsk.).
Ecotoxicology and environmental safety.
2011 Jul; 74(5):1325-30. doi:
10.1016/j.ecoenv.2011.03.009. [PMID: 21496923] - Balam Muñoz, Arnulfo Albores. The role of molecular biology in the biomonitoring of human exposure to chemicals.
International journal of molecular sciences.
2010 Nov; 11(11):4511-25. doi:
10.3390/ijms11114511. [PMID: 21151453] - Fumio Kondo, Yoshitomo Ikai, Rumiko Hayashi, Masanao Okumura, Satoshi Takatori, Hiroyuki Nakazawa, Shun-ichiro Izumi, Tsunehisa Makino. Determination of five phthalate monoesters in human urine using gas chromatography-mass spectrometry.
Bulletin of environmental contamination and toxicology.
2010 Jul; 85(1):92-6. doi:
10.1007/s00128-010-0051-8. [PMID: 20574658] - Lizbeth López-Carrillo, Raúl U Hernández-Ramírez, Antonia M Calafat, Luisa Torres-Sánchez, Marcia Galván-Portillo, Larry L Needham, Rubén Ruiz-Ramos, Mariano E Cebrián. Exposure to phthalates and breast cancer risk in northern Mexico.
Environmental health perspectives.
2010 Apr; 118(4):539-44. doi:
10.1289/ehp.0901091. [PMID: 20368132] - M Clara, G Windhofer, W Hartl, K Braun, M Simon, O Gans, C Scheffknecht, A Chovanec. Occurrence of phthalates in surface runoff, untreated and treated wastewater and fate during wastewater treatment.
Chemosphere.
2010 Feb; 78(9):1078-84. doi:
10.1016/j.chemosphere.2009.12.052. [PMID: 20096917] - Jennifer J Adibi, Robin M Whyatt, Russ Hauser, Hari K Bhat, Barbara J Davis, Antonia M Calafat, Lori A Hoepner, Frederica P Perera, Deliang Tang, Paige L Williams. Transcriptional biomarkers of steroidogenesis and trophoblast differentiation in the placenta in relation to prenatal phthalate exposure.
Environmental health perspectives.
2010 Feb; 118(2):291-6. doi:
10.1289/ehp.0900788. [PMID: 20123604] - Jennifer David Peck, Anne M Sweeney, Elane Symanski, Joseph Gardiner, Manori J Silva, Antonia M Calafat, Susan L Schantz. Intra- and inter-individual variability of urinary phthalate metabolite concentrations in Hmong women of reproductive age.
Journal of exposure science & environmental epidemiology.
2010 Jan; 20(1):90-100. doi:
10.1038/jes.2009.4. [PMID: 19223940] - Lesa L Aylward, Sean M Hays, Michelle Gagné, Kannan Krishnan. Derivation of Biomonitoring Equivalents for di-n-butyl phthalate (DBP), benzylbutyl phthalate (BzBP), and diethyl phthalate (DEP).
Regulatory toxicology and pharmacology : RTP.
2009 Dec; 55(3):259-67. doi:
10.1016/j.yrtph.2009.09.003. [PMID: 19751787] - Susan Sumner, Rodney Snyder, Jason Burgess, Christina Myers, Rochelle Tyl, Carol Sloan, Timothy Fennell. Metabolomics in the assessment of chemical-induced reproductive and developmental outcomes using non-invasive biological fluids: application to the study of butylbenzyl phthalate.
Journal of applied toxicology : JAT.
2009 Nov; 29(8):703-14. doi:
10.1002/jat.1462. [PMID: 19731247] - John D Meeker, Howard Hu, David E Cantonwine, Hector Lamadrid-Figueroa, Antonia M Calafat, Adrienne S Ettinger, Mauricio Hernandez-Avila, Rita Loch-Caruso, Martha María Téllez-Rojo. Urinary phthalate metabolites in relation to preterm birth in Mexico city.
Environmental health perspectives.
2009 Oct; 117(10):1587-92. doi:
10.1289/ehp.0800522. [PMID: 20019910] - Matthias Wittassek, Juergen Angerer, Marike Kolossa-Gehring, Sebastian Daniel Schäfer, Walter Klockenbusch, Lorenz Dobler, Andreas K Günsel, Antje Müller, Gerhard Andreas Wiesmüller. Fetal exposure to phthalates--a pilot study.
International journal of hygiene and environmental health.
2009 Sep; 212(5):492-8. doi:
10.1016/j.ijheh.2009.04.001. [PMID: 19423389] - J W Gorsuch, C A Staples, D Brown, R Enste-Diefenbach. Vapor-phase toxicity of butylbenzyl phthalate to three plant species: white mustard, chinese cabbage, and white clover.
Bulletin of environmental contamination and toxicology.
2008 Aug; 81(2):220-4. doi:
10.1007/s00128-008-9449-y. [PMID: 18465066] - Mary S Wolff, Stephanie M Engel, Gertrud S Berkowitz, Xiaoyun Ye, Manori J Silva, Chenbo Zhu, James Wetmur, Antonia M Calafat. Prenatal phenol and phthalate exposures and birth outcomes.
Environmental health perspectives.
2008 Aug; 116(8):1092-7. doi:
10.1289/ehp.11007. [PMID: 18709157] - Matthias Wittassek, Jürgen Angerer. Phthalates: metabolism and exposure.
International journal of andrology.
2008 Apr; 31(2):131-8. doi:
10.1111/j.1365-2605.2007.00837.x. [PMID: 18070048] - Jennifer J Adibi, Robin M Whyatt, Paige L Williams, Antonia M Calafat, David Camann, Robert Herrick, Heather Nelson, Hari K Bhat, Frederica P Perera, Manori J Silva, Russ Hauser. Characterization of phthalate exposure among pregnant women assessed by repeat air and urine samples.
Environmental health perspectives.
2008 Apr; 116(4):467-73. doi:
10.1289/ehp.10749. [PMID: 18414628] - John D Meeker, Antonia M Calafat, Russ Hauser. Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men.
Environmental health perspectives.
2007 Jul; 115(7):1029-34. doi:
10.1289/ehp.9852. [PMID: 17637918] - Hiroaki Itoh, Kikuo Yoshida, Shigeki Masunaga. Quantitative identification of unknown exposure pathways of phthalates based on measuring their metabolites in human urine.
Environmental science & technology.
2007 Jul; 41(13):4542-7. doi:
10.1021/es062926y. [PMID: 17695894] - Holger M Koch, Kerstin Becker, Matthias Wittassek, Margarete Seiwert, Jürgen Angerer, Marike Kolossa-Gehring. Di-n-butylphthalate and butylbenzylphthalate - urinary metabolite levels and estimated daily intakes: pilot study for the German Environmental Survey on children.
Journal of exposure science & environmental epidemiology.
2007 Jul; 17(4):378-87. doi:
10.1038/sj.jes.7500526. [PMID: 17006438] - Matthias Wittassek, Gerhard Andreas Wiesmüller, Holger Martin Koch, Rolf Eckard, Lorenz Dobler, Johannes Müller, Jürgen Angerer, Christoph Schlüter. Internal phthalate exposure over the last two decades--a retrospective human biomonitoring study.
International journal of hygiene and environmental health.
2007 May; 210(3-4):319-33. doi:
10.1016/j.ijheh.2007.01.037. [PMID: 17400024] - Wen-Lan Li, Yu-Bin Ji, Da-Lei Zhang, Yu-Qi Fan. [Identification of metabolites of environmental hormone butylbenzyl phthalate in mice urine by liquid chromatography/ion trap mass spectrometry].
Huan jing ke xue= Huanjing kexue.
2007 Mar; 28(3):627-32. doi:
. [PMID: 17633646] - Peter Roslev, Katrin Vorkamp, Jakob Aarup, Klavs Frederiksen, Per Halkjaer Nielsen. Degradation of phthalate esters in an activated sludge wastewater treatment plant.
Water research.
2007 Mar; 41(5):969-76. doi:
10.1016/j.watres.2006.11.049. [PMID: 17258263] - Mary S Wolff, Susan L Teitelbaum, Gayle Windham, Susan M Pinney, Julie A Britton, Carol Chelimo, James Godbold, Frank Biro, Lawrence H Kushi, Christine M Pfeiffer, Antonia M Calafat. Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls.
Environmental health perspectives.
2007 Jan; 115(1):116-21. doi:
10.1289/ehp.9488. [PMID: 17366830] - Russ Hauser, John D Meeker, Susan Duty, Manori J Silva, Antonia M Calafat. Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites.
Epidemiology (Cambridge, Mass.).
2006 Nov; 17(6):682-91. doi:
10.1097/01.ede.0000235996.89953.d7. [PMID: 17003688] - Pei-Shan Liu, Yi-Yin Chen. Butyl benzyl phthalate blocks Ca2+ signaling coupled with purinoceptor in rat PC12 cells.
Toxicology and applied pharmacology.
2006 Jan; 210(1-2):136-41. doi:
10.1016/j.taap.2005.09.012. [PMID: 16360712] - Yohko Fujimoto, Kumiko Usa, Satoru Sakuma. Effects of endocrine disruptors on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes.
Prostaglandins, leukotrienes, and essential fatty acids.
2005 Dec; 73(6):447-52. doi:
10.1016/j.plefa.2005.08.002. [PMID: 16181777] - Susan M Duty, Robin M Ackerman, Antonia M Calafat, Russ Hauser. Personal care product use predicts urinary concentrations of some phthalate monoesters.
Environmental health perspectives.
2005 Nov; 113(11):1530-5. doi:
10.1289/ehp.8083. [PMID: 16263507] - Holger M Koch, Ralf Preuss, Hans Drexler, Jürgen Angerer. Exposure of nursery school children and their parents and teachers to di-n-butylphthalate and butylbenzylphthalate.
International archives of occupational and environmental health.
2005 Apr; 78(3):223-9. doi:
10.1007/s00420-004-0570-x. [PMID: 15776263] - N Shimada, K Yamauchi. Characteristics of 3,5,3'-triiodothyronine (T3)-uptake system of tadpole red blood cells: effect of endocrine-disrupting chemicals on cellular T3 response.
The Journal of endocrinology.
2004 Dec; 183(3):627-37. doi:
10.1677/joe.1.05893. [PMID: 15590988] - Wen-lan Li, Yu-bin Ji, Yu-nan Yang, Bo Yang. [Reproductive toxicity and functional mechanism of the environmental hormone butylbenzyl phthalate].
Huan jing ke xue= Huanjing kexue.
2004 Jan; 25(1):1-6. doi:
. [PMID: 15330411] - Akinori Ishihara, Norihito Nishiyama, Shin-ichiro Sugiyama, Kiyoshi Yamauchi. The effect of endocrine disrupting chemicals on thyroid hormone binding to Japanese quail transthyretin and thyroid hormone receptor.
General and comparative endocrinology.
2003 Oct; 134(1):36-43. doi:
10.1016/s0016-6480(03)00197-7. [PMID: 13129501] - Pei-Shan Liu, Chih-Ming Lin, Chien-Yuan Pan, Lung-Sen Kao, Fu-Wei Tseng. Butyl benzyl phthalate blocks Ca2+ signaling and catecholamine secretion coupled with nicotinic acetylcholine receptors in bovine adrenal chromaffin cells.
Neurotoxicology.
2003 Jan; 24(1):97-105. doi:
10.1016/s0161-813x(02)00154-7. [PMID: 12564386] - Hermann Fromme, Thomas Küchler, Thomas Otto, Konstanze Pilz, Josef Müller, Andrea Wenzel. Occurrence of phthalates and bisphenol A and F in the environment.
Water research.
2002 Mar; 36(6):1429-38. doi:
10.1016/s0043-1354(01)00367-0. [PMID: 11996333] - F Martens, M Martens. [Determination of monoester metabolites of butylbenzyl phthalate (BBP) by GC-MS in the urine of exposed workers].
Acta clinica Belgica.
2002; 57 Suppl 1(?):16-23. doi:
. [PMID: 11974437] - W A Anderson, L Castle, M J Scotter, R C Massey, C Springall. A biomarker approach to measuring human dietary exposure to certain phthalate diesters.
Food additives and contaminants.
2001 Dec; 18(12):1068-74. doi:
10.1080/02652030110050113. [PMID: 11761117]