2-Hydroxybutanebis(thioic S-acid) (BioDeep_00000183702)
human metabolite blood metabolite
代谢物信息卡片
2-Hydroxybutanebis(thioic S-acid)
化学式: C4H6O3S2 (165.9758366)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(C(=O)S)O)C(=O)S
InChI: InChI=1S/C4H6O3S2/c5-2(4(7)9)1-3(6)8/h2,5H,1H2,(H,6,8)(H,7,9)
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Reena Singh, Neetu Gautam, Anurag Mishra, Rajiv Gupta. Heavy metals and living systems: An overview.
Indian journal of pharmacology.
2011 May; 43(3):246-53. doi:
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Clinical & developmental immunology.
2011; 2011(?):790460. doi:
10.1155/2011/790460. [PMID: 21603161] - Jurij J Hostynek, Frank Dreher, Howard I Maibach. Human skin retention and penetration of a copper tripeptide in vitro as function of skin layer towards anti-inflammatory therapy.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2010 Nov; 59(11):983-8. doi:
10.1007/s00011-010-0214-4. [PMID: 20703511] - Mohammad S Iqbal, Syed G Taqi, Muhammad Arif, Muhammad Wasim, Muhammad Sher. In vitro distribution of gold in serum proteins after incubation of sodium aurothiomalate and auranofin with human blood and its pharmacological significance.
Biological trace element research.
2009 Sep; 130(3):204-9. doi:
10.1007/s12011-009-8330-0. [PMID: 19194667] - Roderick P Regala, E Aubrey Thompson, Alan P Fields. Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells.
Cancer research.
2008 Jul; 68(14):5888-95. doi:
10.1158/0008-5472.can-08-0438. [PMID: 18632643] - Paul L Wood, M Amin Khan, Joseph R Moskal. Mechanism of action of the disease-modifying anti-arthritic thiol agents D-penicillamine and sodium aurothiomalate: restoration of cellular free thiols and sequestration of reactive aldehydes.
European journal of pharmacology.
2008 Feb; 580(1-2):48-54. doi:
10.1016/j.ejphar.2007.10.066. [PMID: 18022616] - Hiroki Osawa, Hideaki Matsumoto. Cytotoxic thio-malate is transported by both an aluminum-responsive malate efflux pathway in wheat and the MAE1 malate permease in Schizosaccharomyces pombe.
Planta.
2006 Jul; 224(2):462-71. doi:
10.1007/s00425-006-0220-5. [PMID: 16450171] - Alfredo de la Escosura-Muñiz, María Begoña González-García, Agustín Costa-García. Determination of human serum albumin using aurothiomalate as electroactive label.
Analytical and bioanalytical chemistry.
2006 Feb; 384(3):742-50. doi:
10.1007/s00216-005-0213-4. [PMID: 16372180] - Patricia López, Jesús Gómez, Lourdes Mozo, Carmen Gutiérrez, Ana Suárez. Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs.
Arthritis research & therapy.
2006; 8(2):R42. doi:
10.1186/ar1897. [PMID: 16507146] - Shoji Sugii. [Adverse effects of DMARDs in treatment of rheumatoid arthritis].
Nihon rinsho. Japanese journal of clinical medicine.
2005 Jan; 63 Suppl 1(?):566-72. doi:
NULL. [PMID: 15799419] - Aida Chircorian, Amy M Barrios. Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I).
Bioorganic & medicinal chemistry letters.
2004 Oct; 14(20):5113-6. doi:
10.1016/j.bmcl.2004.07.073. [PMID: 15380210] - Sofia Ernestam, Jon Lampa, Siv Rogberg, Johan Rönnelid, Lars Klareskog, Ingiäld Hafström. Evidence for immunostimulatory effects of intramuscular gold in patients with rheumatoid arthritis: correlation with skin reactions.
The Journal of rheumatology.
2003 Aug; 30(8):1748-55. doi:
NULL. [PMID: 12913930] - T K Kvien, H K Zeidler, P Hannonen, F A Wollheim, O Førre, I Hafström, J P Kaltwasser, M Leirisalo-Repo, B Manger, L Laasonen, H Prestele, P Kurki. Long term efficacy and safety of cyclosporin versus parenteral gold in early rheumatoid arthritis: a three year study of radiographic progression, renal function, and arterial hypertension.
Annals of the rheumatic diseases.
2002 Jun; 61(6):511-6. doi:
10.1136/ard.61.6.511. [PMID: 12006323] - Ake Svensson, Halvor Möller, Bert Björkner, Magnus Bruze, Ido Leden, Jan Theander, Kjell Ohlsson, Carina Linder. Rheumatoid arthritis, gold therapy, contact allergy and blood cytokines.
BMC dermatology.
2002; 2(?):2. doi:
10.1186/1471-5945-2-2. [PMID: 11860615] - Peter C Taylor. VEGF and imaging of vessels in rheumatoid arthritis.
Arthritis research.
2002; 4 Suppl 3(?):S99-107. doi:
10.1186/ar582. [PMID: 12110128] - K Kishimoto, K Iwatsuki, H Akiba, Y Motoki, F Kaneko. Subcorneal pustular dermatosis-type IgA pemphigus induced by thiol drugs.
European journal of dermatology : EJD.
2001 Jan; 11(1):41-4. doi:
NULL. [PMID: 11174137]