3,4-Bis(1H-indol-2-yl)pyrrole-2,5-dione (BioDeep_00000183697)
human metabolite blood metabolite
代谢物信息卡片
化学式: C20H13N3O2 (327.1007718)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C=C(N2)C3=C(C(=O)NC3=O)C4=CC5=CC=CC=C5N4
InChI: InChI=1S/C20H13N3O2/c24-19-17(15-9-11-5-1-3-7-13(11)21-15)18(20(25)23-19)16-10-12-6-2-4-8-14(12)22-16/h1-10,21-22H,(H,23,24,25)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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BioCyc(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Dennis J Templeton, Myo-Sabai Aye, Joshua Rady, Fang Xu, Janet V Cross. Purification of reversibly oxidized proteins (PROP) reveals a redox switch controlling p38 MAP kinase activity.
PloS one.
2010 Nov; 5(11):e15012. doi:
10.1371/journal.pone.0015012. [PMID: 21085594] - Ana Fortuño, Julen Bidegain, Ana Baltanás, María U Moreno, Laura Montero, Manuel F Landecho, Oscar Beloqui, Javier Díez, Guillermo Zalba. Is leptin involved in phagocytic NADPH oxidase overactivity in obesity? Potential clinical implications.
Journal of hypertension.
2010 Sep; 28(9):1944-50. doi:
10.1097/hjh.0b013e32833c21af. [PMID: 20577124] - Ansar A Khan, Bieuwke S Dragt, Robert J Porte, Geny M M Groothuis. Regulation of VDR expression in rat and human intestine and liver--consequences for CYP3A expression.
Toxicology in vitro : an international journal published in association with BIBRA.
2010 Apr; 24(3):822-9. doi:
10.1016/j.tiv.2009.12.011. [PMID: 20006981] - Theresa E Kitos, Chrystal M Y Choi, Rosemary B Cornell. Angiotensin stimulates phosphatidylcholine synthesis via a pathway involving diacylglycerol, protein kinase C, ERK1/2, and CTP:phosphocholine cytidylyltransferase.
Biochimica et biophysica acta.
2006 Feb; 1761(2):272-9. doi:
10.1016/j.bbalip.2006.02.014. [PMID: 16580250] - Manuel Miranda, Christine C Wu, Tatiana Sorkina, Davin R Korstjens, Alexander Sorkin. Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C.
The Journal of biological chemistry.
2005 Oct; 280(42):35617-24. doi:
10.1074/jbc.m506618200. [PMID: 16109712] - Mihaela Levitchi, Caroline Fradette, Anne-Marie Bleau, Dorothée Michaud, Oksana Kourylko, Mathieu Arcand, Patrick du Souich. Signal transduction pathways implicated in the decrease in CYP1A1, 1A2 and 3A6 activity produced by serum from rabbits and humans with an inflammatory reaction.
Biochemical pharmacology.
2004 Aug; 68(3):573-82. doi:
10.1016/j.bcp.2004.04.002. [PMID: 15242823] - Nakako Kurimoto, Yong-Shan Nan, Zhi-Yong Chen, Guo-Gang Feng, Toru Komatsu, Nobuhisa Kandatsu, Junken Ko, Norio Kawai, Naohisa Ishikawa. Effects of specific signal transduction inhibitors on increased permeability across rat endothelial monolayers induced by neuropeptide Y or VEGF.
American journal of physiology. Heart and circulatory physiology.
2004 Jul; 287(1):H100-6. doi:
10.1152/ajpheart.00922.2003. [PMID: 14975929] - David A Vesey, Catherine Cheung, Leila Cuttle, Zoltan Endre, Glenda Gobe, David W Johnson. Interleukin-1beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta-dependent mechanism.
The Journal of laboratory and clinical medicine.
2002 Nov; 140(5):342-50. doi:
10.1067/mlc.2002.128468. [PMID: 12434136] - Sylvie A Terlouw, Claudia Graeff, Pascal H E Smeets, Gert Fricker, Frans G M Russel, Rosalinde Masereeuw, David S Miller. Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule.
The Journal of pharmacology and experimental therapeutics.
2002 May; 301(2):578-85. doi:
10.1124/jpet.301.2.578. [PMID: 11961059] - Silvia Riemer, Sonja Gebhard, Frank Beier, Ernst Pöschl, Klaus von der Mark. Role of c-fos in the regulation of type X collagen gene expression by PTH and PTHrP: localization of a PTH/PTHrP-responsive region in the human COL10A1 enhancer.
Journal of cellular biochemistry.
2002; 86(4):688-99. doi:
10.1002/jcb.10260. [PMID: 12210735] - P Rojnuckarin, K Kaushansky. Actin reorganization and proplatelet formation in murine megakaryocytes: the role of protein kinase calpha.
Blood.
2001 Jan; 97(1):154-61. doi:
10.1182/blood.v97.1.154. [PMID: 11133755]