9-[2-(Phosphanylmethoxy)propyl]purin-6-amine (BioDeep_00000183645)
human metabolite blood metabolite
代谢物信息卡片
化学式: C9H14N5OP (239.0936)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: CC(CN1C=NC2=C(N=CN=C21)N)OCP
InChI: InChI=1S/C9H14N5OP/c1-6(15-5-16)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5,16H2,1H3,(H2,10,11,12)
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Deborah Heydenburg Fuller, Premeela Rajakumar, Jenny W Che, Amithi Narendran, Julia Nyaundi, Heather Michael, Eric J Yager, Cristy Stagnar, Brendon Wahlberg, Rachel Taber, Joel R Haynes, Fiona C Cook, Peter Ertl, John Tite, Angela M Amedee, Michael Murphey-Corb. Therapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaques.
PloS one.
2012; 7(3):e33715. doi:
10.1371/journal.pone.0033715. [PMID: 22442716] - Abdul Jabbar Al-Rajab, Lyne Sabourin, Ralph Chapman, David R Lapen, Edward Topp. Fate of the antiretroviral drug tenofovir in agricultural soil.
The Science of the total environment.
2010 Oct; 408(22):5559-64. doi:
10.1016/j.scitotenv.2010.07.074. [PMID: 20800877] - Gülşen Ozkaya Sahin, Emma J Bowles, Joe Parker, Hannes Uchtenhagen, Enas Sheik-Khalil, Stephen Taylor, Oliver G Pybus, Barbro Mäkitalo, Lilian Walther-Jallow, Mats Spångberg, Rigmor Thorstensson, Adnane Achour, Eva Maria Fenyö, Guillaume B E Stewart-Jones, Anna-Lena Spetz. Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.
PLoS pathogens.
2010 Sep; 6(9):e1001084. doi:
10.1371/journal.ppat.1001084. [PMID: 20824092] - Pierre Sellier, Abdelkrim Mannioui, Olivier Bourry, Nathalie Dereuddre-Bosquet, Benoit Delache, Patricia Brochard, Julien Calvo, Sophie Prévot, Pierre Roques. Antiretroviral treatment start-time during primary SIV(mac) infection in macaques exerts a different impact on early viral replication and dissemination.
PloS one.
2010 May; 5(5):e10570. doi:
10.1371/journal.pone.0010570. [PMID: 20485497] - Koen K A Van Rompay, Jeffrey A Johnson, Emily J Blackwood, Raman P Singh, Jonathan Lipscomb, Timothy B Matthews, Marta L Marthas, Niels C Pedersen, Norbert Bischofberger, Walid Heneine, Thomas W North. Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection.
Retrovirology.
2007 Apr; 4(?):25. doi:
10.1186/1742-4690-4-25. [PMID: 17417971] - Karin J Metzner, James M Binley, Agegnehu Gettie, Preston Marx, Douglas F Nixon, Ruth I Connor. Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques.
Retrovirology.
2006 Dec; 3(?):97. doi:
10.1186/1742-4690-3-97. [PMID: 17184540] - Peter Emau, Yonghou Jiang, Michael B Agy, Baoping Tian, Girma Bekele, Che-Chung Tsai. Post-exposure prophylaxis for SIV revisited: animal model for HIV prevention.
AIDS research and therapy.
2006 Nov; 3(?):29. doi:
10.1186/1742-6405-3-29. [PMID: 17132170] - Max W Richardson, Andrij E Sverstiuk, Peter Silvera, Jack Greenhouse, Julianna Lisziewicz, Franco Lori, Kamel Khalili, Mark G Lewis, Jay Rappaport. T-cell receptor excision circles (TREC) in SHIV 89.6p and SIVmac251 models of HIV-1 infection.
DNA and cell biology.
2004 Jan; 23(1):1-13. doi:
10.1089/104454904322745880. [PMID: 14965468]
