Perfluorononanoic acid (BioDeep_00000018362)
human metabolite Industrial Pollutants
代谢物信息卡片
Perfluorononanoic acid
化学式: C9HF17O2 (463.97050899999994)
中文名称: 十七氟壬酸, 全氟壬酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=O)(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O
InChI: InChI=1S/C9HF17O2/c10-2(11,1(27)28)3(12,13)4(14,15)5(16,17)6(18,19)7(20,21)8(22,23)9(24,25)26/h(H,27,28)
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:38397
- PubChem: 67821
- HMDB: HMDB0061739
- ChEMBL: CHEMBL426404
- CAS: 375-95-1
- PMhub: MS000007235
- RefMet: Perfluorononanoic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Emily Marques, Marisa Pfohl, Wei Wei, Giuseppe Tarantola, Lucie Ford, Ogochukwu Amaeze, Jessica Alesio, Sangwoo Ryu, Xuelian Jia, Hao Zhu, Geoffrey D Bothun, Angela Slitt. Replacement per- and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human hepatocytes.
Toxicology and applied pharmacology.
2022 05; 442(?):115991. doi:
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Environmental health perspectives.
2022 03; 130(3):37005. doi:
10.1289/ehp10118. [PMID: 35266797] - Santosh Lamichhane, Heli Siljander, Daniel Duberg, Jarno Honkanen, Suvi M Virtanen, Matej Orešič, Mikael Knip, Tuulia Hyötyläinen. Exposure to per- and polyfluoroalkyl substances associates with an altered lipid composition of breast milk.
Environment international.
2021 12; 157(?):106855. doi:
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The Journal of clinical endocrinology and metabolism.
2021 10; 106(11):e4427-e4437. doi:
10.1210/clinem/dgab476. [PMID: 34181018] - Randi Grønnestad, Silje Modahl Johanson, Mette H B Müller, Daniel Schlenk, Philip Tanabe, Åse Krøkje, Veerle L B Jaspers, Bjørn Munro Jenssen, Erik M Ræder, Jan L Lyche, Qingyang Shi, Augustine Arukwe. Effects of an environmentally relevant PFAS mixture on dopamine and steroid hormone levels in exposed mice.
Toxicology and applied pharmacology.
2021 10; 428(?):115670. doi:
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Environmental health perspectives.
2021 09; 129(9):97011. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2021 09; 104(?):52-57. doi:
10.1016/j.reprotox.2021.06.016. [PMID: 34182087] - Damaskini Valvi, Kurt Højlund, Brent A Coull, Flemming Nielsen, Pal Weihe, Philippe Grandjean. Life-course Exposure to Perfluoroalkyl Substances in Relation to Markers of Glucose Homeostasis in Early Adulthood.
The Journal of clinical endocrinology and metabolism.
2021 07; 106(8):2495-2504. doi:
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International journal of hygiene and environmental health.
2021 06; 235(?):113757. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2021 04; 180(2):277-294. doi:
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The Science of the total environment.
2021 Feb; 755(Pt 1):142904. doi:
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Ecotoxicology and environmental safety.
2021 Jan; 208(?):111625. doi:
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Environment international.
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Thyroid : official journal of the American Thyroid Association.
2020 11; 30(11):1556-1565. doi:
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Environmental health : a global access science source.
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Archives of toxicology.
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Reproductive toxicology (Elmsford, N.Y.).
2019 12; 90(?):8-14. doi:
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Environmental health : a global access science source.
2019 11; 18(1):97. doi:
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The Journal of clinical endocrinology and metabolism.
2019 11; 104(11):5338-5348. doi:
10.1210/jc.2019-00385. [PMID: 31216000] - Shilpi Singh, Shio Kumar Singh. Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
Ecotoxicology and environmental safety.
2019 Apr; 170(?):590-599. doi:
10.1016/j.ecoenv.2018.12.034. [PMID: 30576894] - Kady Palmer, Jacqueline T Bangma, Jessica L Reiner, Robert K Bonde, Jeffrey E Korte, Ashley S P Boggs, John A Bowden. Per- and polyfluoroalkyl substances (PFAS) in plasma of the West Indian manatee (Trichechus manatus).
Marine pollution bulletin.
2019 Mar; 140(?):610-615. doi:
10.1016/j.marpolbul.2019.02.010. [PMID: 30803684] - Ida Hallberg, Jacklin Kjellgren, Sara Persson, Stefan Örn, Ylva Sjunnesson. Perfluorononanoic acid (PFNA) alters lipid accumulation in bovine blastocysts after oocyte exposure during in vitro maturation.
Reproductive toxicology (Elmsford, N.Y.).
2019 03; 84(?):1-8. doi:
10.1016/j.reprotox.2018.11.005. [PMID: 30502403] - Shilpi Singh, Shio Kumar Singh. Chronic exposure to perfluorononanoic acid impairs spermatogenesis, steroidogenesis and fertility in male mice.
Journal of applied toxicology : JAT.
2019 03; 39(3):420-431. doi:
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BMJ open.
2019 02; 9(2):e024189. doi:
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Archives of toxicology.
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Pediatric research.
2018 12; 84(6):854-860. doi:
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Environmental health perspectives.
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Toxicological sciences : an official journal of the Society of Toxicology.
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Environment international.
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Reproductive toxicology (Elmsford, N.Y.).
2017 04; 69(?):53-59. doi:
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Toxicology.
2017 Mar; 378(?):37-52. doi:
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Chemosphere.
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Guang pu xue yu guang pu fen xi = Guang pu.
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Reproductive toxicology (Elmsford, N.Y.).
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Chemosphere.
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