3-Methyl-3-propan-2-ylcyclohexan-1-ol (BioDeep_00000183592)
human metabolite blood metabolite
代谢物信息卡片
3-Methyl-3-propan-2-ylcyclohexan-1-ol
化学式: C10H20O (156.151407)
中文名称:
谱图信息:
最多检出来源 Mus musculus(blood) 75%
分子结构信息
SMILES: CC(C)C1(C)CCCC(O)C1
InChI: InChI=1S/C10H20O/c1-8(2)10(3)6-4-5-9(11)7-10/h8-9,11H,4-7H2,1-3H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Naoki Hiki, Michio Kaminishi, Kenjiro Yasuda, Noriya Uedo, Masumi Kobari, Terufumi Sakai, Takashi Hiratsuka, Kyota Ohno, Hajime Honjo, Sachiyo Nomura, Naohisa Yahagi, Hisao Tajiri, Hiroaki Suzuki. Multicenter phase II randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.
2012 Mar; 24(2):79-86. doi:
10.1111/j.1443-1661.2011.01163.x. [PMID: 22348831] - Sureewan Duangjit, Yasuko Obata, Hiromu Sano, Shingo Kikuchi, Yoshinori Onuki, Praneet Opanasopit, Tanasait Ngawhirunpat, Yoshie Maitani, Kozo Takayama. Menthosomes, novel ultradeformable vesicles for transdermal drug delivery: optimization and characterization.
Biological & pharmaceutical bulletin.
2012; 35(10):1720-8. doi:
10.1248/bpb.b12-00343. [PMID: 23037161] - N Hiki, M Kaminishi, T Hasunuma, M Nakamura, S Nomura, N Yahagi, H Tajiri, H Suzuki. A phase I study evaluating tolerability, pharmacokinetics, and preliminary efficacy of L-menthol in upper gastrointestinal endoscopy.
Clinical pharmacology and therapeutics.
2011 Aug; 90(2):221-8. doi:
10.1038/clpt.2011.110. [PMID: 21544078] - Ligang Zhao, Liang Fang, Yan Li, Ni Zheng, Yongnan Xu, Jinghua Wang, Zhonggui He. Effect of (E)-2-isopropyl-5-methylcyclohexyl octadec-9-enoate on transdermal delivery of Aconitum alkaloids.
Drug development and industrial pharmacy.
2011 Mar; 37(3):290-9. doi:
10.3109/03639045.2010.510141. [PMID: 21054218] - Hiroshi Watanabe, Yasuko Obata, Yoshinori Onuki, Kenya Ishida, Kozo Takayama. Different effects of l- and d-menthol on the microstructure of ceramide 5/cholesterol/palmitic acid bilayers.
International journal of pharmaceutics.
2010 Dec; 402(1-2):146-52. doi:
10.1016/j.ijpharm.2010.09.038. [PMID: 20932885] - Wendy Pearson, Ronald S Fletcher, Laima S Kott, Mark B Hurtig. Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata.
BMC complementary and alternative medicine.
2010 May; 10(?):19. doi:
10.1186/1472-6882-10-19. [PMID: 20459798] - Yasuko Obata, Shunichi Utsumi, Hiroshi Watanabe, Masafumi Suda, Yoshihiro Tokudome, Makoto Otsuka, Kozo Takayama. Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers.
International journal of pharmaceutics.
2010 Apr; 389(1-2):18-23. doi:
10.1016/j.ijpharm.2010.01.007. [PMID: 20079819] - Hiroshi Watanabe, Yasuko Obata, Kenya Ishida, Kozo Takayama. Effect of l-menthol on the thermotropic behavior of ceramide 2/cholesterol mixtures as a model for the intercellular lipids in stratum corneum.
Colloids and surfaces. B, Biointerfaces.
2009 Oct; 73(1):116-21. doi:
10.1016/j.colsurfb.2009.05.007. [PMID: 19505808] - Ligang Zhao, Yan Li, Liang Fang, Zhonggui He, Xuntao Liu, Lin Wang, Yongnan Xu, Changshu Ren. Transdermal delivery of tolterodine by O-acylmenthol: In vitro/in vivo correlation.
International journal of pharmaceutics.
2009 Jun; 374(1-2):73-81. doi:
10.1016/j.ijpharm.2009.03.005. [PMID: 19446762] - Krysztof Cal. Skin disposition of d-camphor and l-menthol alone and together.
Methods and findings in experimental and clinical pharmacology.
2009 May; 31(4):237-40. doi:
10.1358/mf.2009.31.4.1371197. [PMID: 19557201] - Mohammad Rizwan, Mohammed Aqil, Abdul Ahad, Yasmin Sultana, Mushir M Ali. Transdermal delivery of valsartan: I. Effect of various terpenes.
Drug development and industrial pharmacy.
2008 Jun; 34(6):618-26. doi:
10.1080/03639040701833740. [PMID: 18568912] - Bharti Sapra, Subheet Jain, A K Tiwary. Percutaneous permeation enhancement by terpenes: mechanistic view.
The AAPS journal.
2008; 10(1):120-32. doi:
10.1208/s12248-008-9012-0. [PMID: 18446512] - Jorge Luiz Vieira dos Anjos, Diógenes de Sousa Neto, Antonio Alonso. Effects of ethanol/l-menthol on the dynamics and partitioning of spin-labeled lipids in the stratum corneum.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2007 Sep; 67(2):406-12. doi:
10.1016/j.ejpb.2007.02.004. [PMID: 17350812] - Yasuko Obata, Ichiro Hatta, Noboru Ohta, Naomi Kunizawa, Naoto Yagi, Kozo Takayama. Combined effects of ethanol and L-menthol on hairless rat stratum corneum investigated by synchrotron X-ray diffraction.
Journal of controlled release : official journal of the Controlled Release Society.
2006 Oct; 115(3):275-9. doi:
10.1016/j.jconrel.2006.08.005. [PMID: 17011061] - Nils Damann, Markus Rothermel, Barbara G Klupp, Thomas C Mettenleiter, Hanns Hatt, Christian H Wetzel. Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing.
BMC neuroscience.
2006 Jun; 7(?):46. doi:
10.1186/1471-2202-7-46. [PMID: 16762059] - Sunil T K Narishetty, Ramesh Panchagnula. Effect of L-menthol and 1,8-cineole on phase behavior and molecular organization of SC lipids and skin permeation of zidovudine.
Journal of controlled release : official journal of the Controlled Release Society.
2005 Jan; 102(1):59-70. doi:
10.1016/j.jconrel.2004.09.016. [PMID: 15653134] - Masato Katayama, Yasuhito Kato, Shingo Marumo. Synthesis, absolute configuration and biological activities of both enantiomers of 2-(5,7-Dichloro-3-indolyl)propionic acid: a novel dichloroindole auxin and antiauxin.
Bioscience, biotechnology, and biochemistry.
2004 Jun; 68(6):1287-92. doi:
10.1271/bbb.68.1287. [PMID: 15215593] - Mitsuo Miyazawa, Hideki Kawazoe, Mitsuro Hyakumachi. Biopreparation of (-)-(1S,3R,4S,6S)-6-hydroxymenthol and (-)-(1S,3R,4S)-1-hydroxymenthol from 1-menthol by Rhizoctonia solani AG-1-IA and IB.
Natural product research.
2003 Oct; 17(5):307-11. doi:
10.1080/1057563031000072532. [PMID: 14526907] - Makiko Fujii, Yasuhiro Takeda, Minako Yoshida, Naoki Utoguchi, Mitsuo Matsumoto, Yoshiteru Watanabe. Comparison of skin permeation enhancement by 3-l-menthoxypropane-1,2-diol and l-menthol: the permeation of indomethacin and antipyrine through Yucatan micropig skin and changes in infrared spectra and X-ray diffraction patterns of stratum corneum.
International journal of pharmaceutics.
2003 Jun; 258(1-2):217-23. doi:
10.1016/s0378-5173(03)00205-9. [PMID: 12753768] - Jun-Ichi Sudo, Hiroaki Iwase, Kimio Higashiyama, Katsuhiko Kakuno, Fumiji Miyasaka, Takashi Meguro, Kozo Takayama. Elevation of plasma levels of L-dopa in transdermal administration of L-dopa-butylester in rats.
Drug development and industrial pharmacy.
2002 Jan; 28(1):59-65. doi:
10.1081/ddc-120001486. [PMID: 11858525]