1-(6-Aminopurin-9-yl)-5-methylpyrimidine-2,4-dione (BioDeep_00000183507)
human metabolite blood metabolite
代谢物信息卡片
化学式: C10H9N7O2 (259.0818)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 81.25%
分子结构信息
SMILES: CC1=CN(C(=O)NC1=O)N2C=NC3=C(N=CN=C32)N
InChI: InChI=1S/C10H9N7O2/c1-5-2-16(10(19)15-9(5)18)17-4-14-6-7(11)12-3-13-8(6)17/h2-4H,1H3,(H2,11,12,13)(H,15,18,19)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Guanjie Chen, Edward Ramos, Adebowale Adeyemo, Daniel Shriner, Jie Zhou, Ayo P Doumatey, Hanxia Huang, Michael R Erdos, Norman P Gerry, Alan Herbert, Amy R Bentley, Huichun Xu, Bashira A Charles, Michael F Christman, Charles N Rotimi. UGT1A1 is a major locus influencing bilirubin levels in African Americans.
European journal of human genetics : EJHG.
2012 Apr; 20(4):463-8. doi:
10.1038/ejhg.2011.206. [PMID: 22085899] - Koichi Murata, Hiroyuki Yoshitomi, Shimei Tanida, Masahiro Ishikawa, Kohei Nishitani, Hiromu Ito, Takashi Nakamura. Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis.
Arthritis research & therapy.
2010; 12(3):R86. doi:
10.1186/ar3013. [PMID: 20470394] - Jadranka Sertic, Ljiljana Juricic, Hana Ljubic, Tamara Bozina, Jasna Lovric, Jasenka Markeljevic, Bojan Jelakovic, Marijan Merkler, Zeljko Reiner. Variants of ESR1, APOE, LPL and IL-6 loci in young healthy subjects: association with lipid status and obesity.
BMC research notes.
2009 Oct; 2(?):203. doi:
10.1186/1756-0500-2-203. [PMID: 19804633] - Misty R Saracino, Jeannette Bigler, Yvonne Schwarz, Jyh-Lurn Chang, Shiuying Li, Lin Li, Emily White, John D Potter, Johanna W Lampe. Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism.
The Journal of nutrition.
2009 Mar; 139(3):555-60. doi:
10.3945/jn.108.097279. [PMID: 19141701] - Simone Funke, Eva Morava, Márta Czakó, Gabriella Vida, Tibor Ertl, György Kosztolányi. [Metabolic bone disease in premature infants and genetic polymorphisms].
Orvosi hetilap.
2007 Oct; 148(41):1957-65. doi:
10.1556/oh.2007.28179. [PMID: 17921123] - Jyh-Lurn Chang, Jeannette Bigler, Yvonne Schwarz, Shuying S Li, Lin Li, Irena B King, John D Potter, Johanna W Lampe. UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial.
The Journal of nutrition.
2007 Apr; 137(4):890-7. doi:
10.1093/jn/137.4.890. [PMID: 17374650] - Simone Funke, Eva Morava, Márta Czakó, Gabriella Vida, Tibor Ertl, György Kosztolányi. Influence of genetic polymorphisms on bone disease of preterm infants.
Pediatric research.
2006 Nov; 60(5):607-12. doi:
10.1203/01.pdr.0000242340.45676.5d. [PMID: 16988190] - Sabrina Peterson, Jeannette Bigler, Neilann K Horner, John D Potter, Johanna W Lampe. Cruciferae interact with the UGT1A1*28 polymorphism to determine serum bilirubin levels in humans.
The Journal of nutrition.
2005 May; 135(5):1051-5. doi:
10.1093/jn/135.5.1051. [PMID: 15867280]
