2-(Ethylamino)-N-methyl-N-(p-tolyl)acetamide (BioDeep_00000183485)

   

human metabolite blood metabolite


代谢物信息卡片


2-(ethylamino)-N-methyl-N-(4-methylphenyl)acetamide

化学式: C12H18N2O (206.1419)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 75%

分子结构信息

SMILES: CCNCC(=O)N(C)C1=CC=C(C)C=C1
InChI: InChI=1S/C12H18N2O/c1-4-13-9-12(15)14(3)11-7-5-10(2)6-8-11/h5-8,13H,4,9H2,1-3H3

描述信息

同义名列表

2 个代谢物同义名

2-(ethylamino)-N-methyl-N-(4-methylphenyl)acetamide; 2-(Ethylamino)-N-methyl-N-(p-tolyl)acetamide



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • E A Hewitt, G Armstrong, N Beg, S Katz, T G Vancaillie. Lignocaine plasma levels following topical gel application in laparoscopic and hysteroscopic procedures. Anaesthesia and intensive care. 2012 Mar; 40(2):292-6. doi: 10.1177/0310057x1204000212. [PMID: 22417024]
  • Luciana de Barros Duarte, Elaine Cristine Dantas Móises, Ricardo Carvalho Cavalli, Vera Lucia Lanchote, Geraldo Duarte, Sérgio Pereira da Cunha. Distribution of bupivacaine enantiomers and lidocaine and its metabolite in the placental intervillous space and in the different maternal and fetal compartments in term pregnant women. Journal of clinical pharmacology. 2011 Feb; 51(2):212-7. doi: 10.1177/0091270010365551. [PMID: 20400649]
  • Samir G Sakka. Assessing liver function. Current opinion in critical care. 2007 Apr; 13(2):207-14. doi: 10.1097/mcc.0b013e328012b268. [PMID: 17327744]
  • Ulrich Brennscheidt, Ulrike Brunnmüller, Dietfried Proppe, Peter Thomann, Klaus-Ulrich Seiler. Pharmacokinetics of tilidine and naloxone in patients with severe hepatic impairment. Arzneimittel-Forschung. 2007; 57(2):106-11. doi: 10.1055/s-0031-1296591. [PMID: 17396621]
  • Marcus K H Auth, Dirk Woitaschek, Mechthild Beste, Thomas Schreiter, Hyun Soo Kim, Elsie Oppermann, Ruth E Joplin, Ulrich Baumann, Philip Hilgard, Silvio Nadalin, Bernd H Markus, Roman A Blaheta. Preservation of the synthetic and metabolic capacity of isolated human hepatocytes by coculture with human biliary epithelial cells. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 2005 Apr; 11(4):410-9. doi: 10.1002/lt.20367. [PMID: 15776438]
  • Jadwiga Piwowarska, Julita Kuczyñska, Jan Pachecka. Liquid chromatographic method for the determination of lidocaine and monoethylglycine xylidide in human serum containing various concentrations of bilirubin for the assessment of liver function. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Jun; 805(1):1-5. doi: 10.1016/j.jchromb.2004.01.030. [PMID: 15113532]
  • Barbara Gawrońska-Szklarz, David H Musiał, Andrzej Pawlik, Bartosz Paprota. Effect of experimental diabetes on pharmacokinetic parameters of lidocaine and MEGX in rats. Polish journal of pharmacology. 2003 Jul; 55(4):619-24. doi: NULL. [PMID: 14581721]
  • Alexander Zipprich, Norbert Steudel, Curd Behrmann, Frank Meiss, Ursula Sziegoleit, Wolfgang E Fleig, Gerhard Kleber. Functional significance of hepatic arterial flow reserve in patients with cirrhosis. Hepatology (Baltimore, Md.). 2003 Feb; 37(2):385-92. doi: 10.1053/jhep.2003.50065. [PMID: 12540789]
  • C Mischiati, A C Puviani, M Brogli, S Guarniero, A Sereni, L Breda, D Ricci, D Galavotti, E Morsiani, R Gambari. Modulation of pro-apoptotic (Bax) and anti-apoptotic (Bcl-2) gene expression in isolated porcine hepatocytes perfused within a radial-flow bioreactor after low-temperature storing. The International journal of artificial organs. 2003 Feb; 26(2):139-48. doi: 10.1177/039139880302600208. [PMID: 12653348]
  • Joachim Boldt, Christian Brosch, Stefan Suttner, Sven N Piper, Andreas Lehmann, Christiane Werling. Prophylactic use of the phospodiesterase III inhibitor enoximone in elderly cardiac surgery patients: effect on hemodynamics, inflammation, and markers of organ function. Intensive care medicine. 2002 Oct; 28(10):1462-9. doi: 10.1007/s00134-002-1435-y. [PMID: 12373472]
  • Katarína Sebeková, Viera Kupcová, Reinhard Schinzel, August Heidland. Markedly elevated levels of plasma advanced glycation end products in patients with liver cirrhosis - amelioration by liver transplantation. Journal of hepatology. 2002 Jan; 36(1):66-71. doi: 10.1016/s0168-8278(01)00232-x. [PMID: 11804666]
  • E Morsiani, M Brogli, D Galavotti, T Bellini, D Ricci, P Pazzi, A C Puviani. Long-term expression of highly differentiated functions by isolated porcine hepatocytes perfused in a radial-flow bioreactor. Artificial organs. 2001 Sep; 25(9):740-8. doi: 10.1046/j.1525-1594.2001.06669.x. [PMID: 11722353]
  • M Giuliani, G B Grossi, M Pileri, C Lajolo, G Casparrini. Could local anesthesia while breast-feeding be harmful to infants?. Journal of pediatric gastroenterology and nutrition. 2001 Feb; 32(2):142-4. doi: 10.1097/00005176-200102000-00009. [PMID: 11321382]