2-(1-Phenylpropan-2-yl)-1,3,2-dioxazetidine (BioDeep_00000183418)
human metabolite blood metabolite
代谢物信息卡片
化学式: C10H13NO2 (179.0946)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CC1=CC=CC=C1)N1OCO1
InChI: InChI=1S/C10H13NO2/c1-9(11-12-8-13-11)7-10-5-3-2-4-6-10/h2-6,9H,7-8H2,1H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
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Journal of forensic sciences.
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Clinical toxicology (Philadelphia, Pa.).
2012 Jan; 50(1):39-43. doi:
10.3109/15563650.2011.635148
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Journal of analytical toxicology.
2011 Oct; 35(8):577-82. doi:
10.1093/anatox/35.8.577
. [PMID: 22004678] - Karl B Scheidweiler, Bruce Ladenheim, Allan J Barnes, Jean Lud Cadet, Marilyn A Huestis. (±)-3,4-methylenedioxymethamphetamine and metabolite disposition in plasma and striatum of wild-type and multidrug resistance protein 1a knock-out mice.
Journal of analytical toxicology.
2011 Sep; 35(7):470-80. doi:
10.1093/anatox/35.7.470
. [PMID: 21871156] - Dominik K Biezonski, Jerrold S Meyer. The Nature of 3, 4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonergic Dysfunction: Evidence for and Against the Neurodegeneration Hypothesis.
Current neuropharmacology.
2011 Mar; 9(1):84-90. doi:
10.2174/157015911795017146
. [PMID: 21886568] - Jun Xiong, Jie Chen, Man He, Bin Hu. Simultaneous quantification of amphetamines, caffeine and ketamine in urine by hollow fiber liquid phase microextraction combined with gas chromatography-flame ionization detector.
Talanta.
2010 Aug; 82(3):969-75. doi:
10.1016/j.talanta.2010.06.001
. [PMID: 20678654] - E M P J Garrido, J M P J Garrido, N Milhazes, F Borges, A M Oliveira-Brett. Electrochemical oxidation of amphetamine-like drugs and application to electroanalysis of ecstasy in human serum.
Bioelectrochemistry (Amsterdam, Netherlands).
2010 Aug; 79(1):77-83. doi:
10.1016/j.bioelechem.2009.12.002
. [PMID: 20051327] - J Röhrich, S Zörntlein, J Becker, R Urban. Detection of Delta9-tetrahydrocannabinol and amphetamine-type stimulants in oral fluid using the Rapid Stat point-of-collection drug-testing device.
Journal of analytical toxicology.
2010 Apr; 34(3):155-61. doi:
10.1093/jat/34.3.155
. [PMID: 20406540] - Michael Moawad, Cheang S Khoo, Samiuela Lee, James R Hennell. Simultaneous determination of eight sympathomimetic amines in urine by gas chromatography/mass spectrometry.
Journal of AOAC International.
2010 Jan; 93(1):116-22. doi:
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- Sarah M R Wille, Elke Raes, Pirjo Lillsunde, Teemu Gunnar, Marleen Laloup, Nele Samyn, Asbjørg S Christophersen, Manfred R Moeller, Karin P Hammer, Alain G Verstraete. Relationship between oral fluid and blood concentrations of drugs of abuse in drivers suspected of driving under the influence of drugs.
Therapeutic drug monitoring.
2009 Aug; 31(4):511-9. doi:
10.1097/ftd.0b013e3181ae46ea
. [PMID: 19571773] - Markus R Meyer, Frank T Peters, Hans H Maurer. The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4-methylenedioxyethylamphetamine and its single enantiomers.
Drug metabolism and disposition: the biological fate of chemicals.
2009 Jun; 37(6):1152-6. doi:
10.1124/dmd.108.026203
. [PMID: 19299523] - Adriaan A S Marais, Johannes B Laurens. Rapid GC-MS confirmation of amphetamines in urine by extractive acylation.
Forensic science international.
2009 Jan; 183(1-3):78-86. doi:
10.1016/j.forsciint.2008.10.021
. [PMID: 19081690] - M Sergi, E Bafile, D Compagnone, R Curini, G D'Ascenzo, F S Romolo. Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS.
Analytical and bioanalytical chemistry.
2009 Jan; 393(2):709-18. doi:
10.1007/s00216-008-2456-3
. [PMID: 18982317] - Jing-Shan Chiang, Shang-Da Huang. Simultaneous derivatization and extraction of amphetamine and methylenedioxyamphetamine in urine with headspace liquid-phase microextraction followed by gas chromatography-mass spectrometry.
Journal of chromatography. A.
2008 Mar; 1185(1):19-22. doi:
10.1016/j.chroma.2008.01.038
. [PMID: 18258242] - Ray H Liu, Hsiu-Chuan Liu, Dong-Liang Lin. Distribution of methylenedioxymethamphetamine (MDMA) and methylenedioxyamphetamine (MDA) in postmortem and antemortem specimens.
Journal of analytical toxicology.
2006 Oct; 30(8):545-50. doi:
10.1093/jat/30.8.545
. [PMID: 17132249] - Kirk M Bertelsen, David J Greenblatt, Lisa L von Moltke. Apparent active transport of MDMA is not mediated by P-glycoprotein: a comparison with MDCK and Caco-2 monolayers.
Biopharmaceutics & drug disposition.
2006 Jul; 27(5):219-27. doi:
10.1002/bdd.501
. [PMID: 16552717] - Justin M Holler, Shawn P Vorce, Thomas Z Bosy, Aaron Jacobs. Quantitative and isomeric determination of amphetamine and methamphetamine from urine using a nonprotic elution solvent and R(-)-alpha-methoxy-alpha-trifluoromethylphenylacetic acid chloride derivatization.
Journal of analytical toxicology.
2005 Oct; 29(7):652-7. doi:
10.1093/jat/29.7.652
. [PMID: 16419395] - Alain G Verstraete, Fien V Heyden. Comparison of the sensitivity and specificity of six immunoassays for the detection of amphetamines in urine.
Journal of analytical toxicology.
2005 Jul; 29(5):359-64. doi:
10.1093/jat/29.5.359
. [PMID: 16105261] - Dong-Liang Lin, Hsiu-Chuan Liu, Rea-Ming Yin, Dung-Tsa Chen, Seng-Jaw Soong, Ray H Liu. Effectiveness of multiple internal standards: deuterated analogues of methylenedioxymethamphetamine, methylenedioxyamphetamine, methamphetamine, and amphetamine.
Journal of analytical toxicology.
2004 Nov; 28(8):650-4. doi:
10.1093/jat/28.8.650
. [PMID: 15538959] - Thomas Cairns, Virginia Hill, Michael Schaffer, William Thistle. Amphetamines in washed hair of demonstrated users and workplace subjects.
Forensic science international.
2004 Oct; 145(2-3):137-42. doi:
10.1016/j.forsciint.2004.04.028
. [PMID: 15451085] - C Lora-Tamayo, T Tena, A Rodríguez, D Moreno, J R Sancho, P Enseñat, F Muela. The designer drug situation in Ibiza.
Forensic science international.
2004 Mar; 140(2-3):195-206. doi:
10.1016/j.forsciint.2003.11.021
. [PMID: 15036441] - M E Soares, M Carvalho, H Carmo, F Remião, F Carvalho, M L Bastos. Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis.
Biomedical chromatography : BMC.
2004 Mar; 18(2):125-31. doi:
10.1002/bmc.315
. [PMID: 15039965] - Linda Cleary, James R Docherty. Actions of amphetamine derivatives and cathinone at the noradrenaline transporter.
European journal of pharmacology.
2003 Aug; 476(1-2):31-4. doi:
10.1016/s0014-2999(03)02173-3
. [PMID: 12969746] - Avi A Weinbroum. Importance of early identification of methylenedioxymethamphetamine ('ecstasy') ingestion in victims of motor vehicle accidents.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine.
2003 Mar; 10(1):19-22. doi:
10.1097/00063110-200303000-00006
. [PMID: 12637856] - Stefano Gentili, Alessio Torresi, Remo Marsili, Marcello Chiarotti, Teodora Macchia. Simultaneous detection of amphetamine-like drugs with headspace solid-phase microextraction and gas chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2002 Nov; 780(1):183-92. doi:
10.1016/s1570-0232(02)00522-6
. [PMID: 12383494] - Márcia Carvalho, Gabrielle Hawksworth, Nuno Milhazes, Fernanda Borges, Terrence J Monks, Eduarda Fernandes, Félix Carvalho, Maria Lourdes Bastos. Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells.
Archives of toxicology.
2002 Oct; 76(10):581-8. doi:
10.1007/s00204-002-0381-3
. [PMID: 12373454] - Dennis J Crouch, Rebekah K Hersch, Royer F Cook, James F Frank, J Michael Walsh. A field evaluation of five on-site drug-testing devices.
Journal of analytical toxicology.
2002 Oct; 26(7):493-9. doi:
10.1093/jat/26.7.493
. [PMID: 12423006] - M Pellegrini, F Rosati, R Pacifici, R Zuccaro, F S Romolo, A Lopez. Rapid screening method for determination of Ecstasy and amphetamines in urine samples using gas chromatography-chemical ionisation mass spectrometry.
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2002 Apr; 769(2):243-51. doi:
10.1016/s1570-0232(01)00586-4
. [PMID: 11996490] - Akira Namera, Mikio Yashiki, Tohru Kojima, Makoto Ueki. Automated headspace solid-phase microextraction and in-matrix derivatization for the determination of amphetamine-related drugs in human urine by gas chromatography-mass spectrometry.
Journal of chromatographic science.
2002 Jan; 40(1):19-25. doi:
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. [PMID: 11866382]