Monoisoamyl dimercaptosuccinic acid (BioDeep_00000183400)
human metabolite blood metabolite
代谢物信息卡片
化学式: C9H16O4S2 (252.0489976)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CCC(C(C(=O)O)S)(C(=O)O)S
InChI: InChI=1S/C9H16O4S2/c1-5(2)3-4-9(15,8(12)13)6(14)7(10)11/h5-6,14-15H,3-4H2,1-2H3,(H,10,11)(H,12,13)
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相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Swaran J S Flora, Smrati Bhadauria, Vidhu Pachauri, Abhishek Yadav. Monoisoamyl 2, 3-dimercaptosuccinic acid (MiADMSA) demonstrates higher efficacy by oral route in reversing arsenic toxicity: a pharmacokinetic approach.
Basic & clinical pharmacology & toxicology.
2012 May; 110(5):449-59. doi:
10.1111/j.1742-7843.2011.00836.x. [PMID: 22117535] - Swaran J S Flora, Kapil Bhatt, Nidhi Dwivedi, Vidhu Pachauri, Pramod K Kushwah. Co-administration of meso 2,3-dimercaptosuccinic acid monoesters reduces arsenic concentration and oxidative stress in gallium arsenide exposed rats.
Clinical and experimental pharmacology & physiology.
2011 Jul; 38(7):423-9. doi:
10.1111/j.1440-1681.2011.05529.x. [PMID: 21501211] - Swaran J S Flora, Swapnila Chouhan, Gurusamy M Kannan, Megha Mittal, Harimohan Swarnkar. Combined administration of taurine and monoisoamyl DMSA protects arsenic induced oxidative injury in rats.
Oxidative medicine and cellular longevity.
2008 Oct; 1(1):39-45. doi:
10.4161/oxim.1.1.6481. [PMID: 19794907] - M Modi, S J S Flora. Combined administration of iron and monoisoamyl-DMSA in the treatment of chronic arsenic intoxication in mice.
Cell biology and toxicology.
2007 Nov; 23(6):429-43. doi:
10.1007/s10565-007-9005-2. [PMID: 17453351] - S J S Flora, Smrati Bhadauria, G M Kannan, Nutan Singh. Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
Journal of environmental biology.
2007 Apr; 28(2 Suppl):333-47. doi:
. [PMID: 17929749] - S Bhadauria, S J S Flora. Response of arsenic-induced oxidative stress, DNA damage, and metal imbalance to combined administration of DMSA and monoisoamyl-DMSA during chronic arsenic poisoning in rats.
Cell biology and toxicology.
2007 Mar; 23(2):91-104. doi:
10.1007/s10565-006-0135-8. [PMID: 17086449] - Geetu Saxena, S J S Flora. Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats.
Journal of biochemical and molecular toxicology.
2004; 18(4):221-33. doi:
10.1002/jbt.20027. [PMID: 15452883] - Swaran J S Flora, Manisha Pande, Ashish Mehta. Beneficial effect of combined administration of some naturally occurring antioxidants (vitamins) and thiol chelators in the treatment of chronic lead intoxication.
Chemico-biological interactions.
2003 Jun; 145(3):267-80. doi:
10.1016/s0009-2797(03)00025-5. [PMID: 12732454] - Swaran J S Flora, Ashish Mehta. Haematological, hepatic and renal alterations after repeated oral and intraperitoneal administration of monoisoamyl DMSA. II. Changes in female rats.
Journal of applied toxicology : JAT.
2003 Mar; 23(2):97-102. doi:
10.1002/jat.890. [PMID: 12666153] - S J S Flora, G M Kannan, B P Pant, D K Jaiswal. The efficacy of monoisoamyl ester of dimercaptosuccinic acid in chronic experimental arsenic poisoning in mice.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2003 Jan; 38(1):241-54. doi:
10.1081/ese-120016892. [PMID: 12635830] - Ashish Mehta, G M Kannan, S N Dube, B P Pant, S C Pant, S J S Flora. Haematological, hepatic and renal alterations after repeated oral or intraperitoneal administration of monoisoamyl DMSA. I. Changes in male rats.
Journal of applied toxicology : JAT.
2002 Nov; 22(6):359-69. doi:
10.1002/jat.871. [PMID: 12424740] - S K Tandon, S Singh, S Prasad, S Srivastava, M K J Siddiqui. Reversal of lead-induced oxidative stress by chelating agent, antioxidant, or their combination in the rat.
Environmental research.
2002 Sep; 90(1):61-6. doi:
10.1006/enrs.2002.4386. [PMID: 12359191] - S J S Flora, Rupa Dubey, G M Kannan, R S Chauhan, B P Pant, D K Jaiswal. Meso 2,3-dimercaptosuccinic acid (DMSA) and monoisoamyl DMSA effect on gallium arsenide induced pathological liver injury in rats.
Toxicology letters.
2002 Jun; 132(1):9-17. doi:
10.1016/s0378-4274(02)00034-6. [PMID: 12084615] - Swaran J S Flora, Gurusamy M Kannan, Bhagwat P Pant, Devendra K Jaiswal. Combined administration of oxalic acid, succimer and its analogue for the reversal of gallium arsenide-induced oxidative stress in rats.
Archives of toxicology.
2002 Jun; 76(5-6):269-76. doi:
10.1007/s00204-002-0347-5. [PMID: 12107644]