(8-Methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-methoxy-2-phenylpropanoate (BioDeep_00000183378)
human metabolite blood metabolite
代谢物信息卡片
(8-Methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-methoxy-2-phenylpropanoic acid
化学式: C18H25NO3 (303.1834)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C2CCC1CC(C2)OC(=O)C(COC)C3=CC=CC=C3
InChI: InChI=1S/C18H25NO3/c1-19-14-8-9-15(19)11-16(10-14)22-18(20)17(12-21-2)13-6-4-3-5-7-13/h3-7,14-17H,8-12H2,1-2H3
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Ming-Fu Wang, Yin-Ching Chan, Hsu-Tung Lee, Ling-Zong Hong. 'Regulation of the intracerebroventricular administration of brain-derived neurotrophic factor on baroreflex function and insulin sensitivity in rats'.
The Chinese journal of physiology.
2012 Jun; 55(3):184-91. doi:
10.4077/cjp.2012.baa015. [PMID: 22784283] - Apurva Kumar R Joshi, P S Rajini. Hyperglycemic and stressogenic effects of monocrotophos in rats: evidence for the involvement of acetylcholinesterase inhibition.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2012 Jan; 64(1-2):115-20. doi:
10.1016/j.etp.2010.07.003. [PMID: 20674316] - Mayumi S Botelho-Ono, Hermano V Pina, Karla H F Sousa, Fabiola C Nunes, Isac A Medeiros, Valdir A Braga. Acute superoxide scavenging restores depressed baroreflex sensitivity in renovascular hypertensive rats.
Autonomic neuroscience : basic & clinical.
2011 Jan; 159(1-2):38-44. doi:
10.1016/j.autneu.2010.07.025. [PMID: 20719579] - Renata Juliana da Silva, Nathalia Bernardes, Janaina de O Brito, Iris Callado Sanches, Maria Cláudia Irigoyen, Kátia De Angelis. Simvastatin-induced cardiac autonomic control improvement in fructose-fed female rats.
Clinics (Sao Paulo, Brazil).
2011; 66(10):1793-6. doi:
10.1590/s1807-59322011001000019. [PMID: 22012053] - Joanne L Harrison, Cara M Hildreth, Stephen M Callahan, Ann K Goodchild, Jacqueline K Phillips. Cardiovascular autonomic dysfunction in a novel rodent model of polycystic kidney disease.
Autonomic neuroscience : basic & clinical.
2010 Jan; 152(1-2):60-6. doi:
10.1016/j.autneu.2009.09.019. [PMID: 19825515] - Giulianna R Borges, Helio C Salgado, Carlos Alberto A Silva, Marcos A Rossi, Cibele M Prado, Rubens Fazan. Changes in hemodynamic and neurohumoral control cause cardiac damage in one-kidney, one-clip hypertensive mice.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Dec; 295(6):R1904-13. doi:
10.1152/ajpregu.00107.2008. [PMID: 18832092] - Cheng-Dean Shih, Daih-Huang Kuo, Chi-Wen Huang, Yu-Hua Gu, Fu-An Chen. Autonomic nervous system mediates the cardiovascular effects of Rhodiola sacra radix in rats.
Journal of ethnopharmacology.
2008 Sep; 119(2):284-90. doi:
10.1016/j.jep.2008.07.016. [PMID: 18692558] - Hugo C D Souza, Marli C Martins-Pinge, Valdo J Dias da Silva, Audrey Borghi-Silva, Ada C Gastaldi, João Henrique D Blanco, Geisa C S V Tezini. Heart rate and arterial pressure variability in the experimental renovascular hypertension model in rats.
Autonomic neuroscience : basic & clinical.
2008 May; 139(1-2):38-45. doi:
10.1016/j.autneu.2008.01.001. [PMID: 18276197] - John Ciriello, L Pastor Solano-Flores, M Patricia Rosas-Arellano, Gilbert J Kirouac, Tanja Babic. Medullary pathways mediating the parasubthalamic nucleus depressor response.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Apr; 294(4):R1276-84. doi:
10.1152/ajpregu.00437.2007. [PMID: 18287224] - M Cansev, Y O Ilcol, M S Yilmaz, E Hamurtekin, I H Ulus. Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.
Autonomic & autacoid pharmacology.
2008 Jan; 28(1):41-58. doi:
10.1111/j.1474-8673.2007.00416.x. [PMID: 18257750] - Po-Shiuan Hsieh, Ling-Zong Hong. Augmentation of nitric oxide is crucial for the time-dependent effects of rosiglitazone on blood pressure and baroreflex function in rats.
Journal of hypertension.
2008 Jan; 26(1):83-92. doi:
10.1097/hjh.0b013e3282f11934. [PMID: 18090544] - Li Zhang, Rong Wang, Yurong Zhang, Yunqiu Yu. Application of high performance capillary electrophoresis on toxic alkaloids analysis.
Journal of separation science.
2007 Jun; 30(9):1357-63. doi:
10.1002/jssc.200600363. [PMID: 17623479] - Ling-Zong Hong, Po-Shiuan Hsieh. Hyperinsulinemia instead of insulin resistance induces baroreflex dysfunction in chronic insulin-infused rats.
American journal of hypertension.
2007 Apr; 20(4):451-8. doi:
10.1016/j.amjhyper.2006.11.004. [PMID: 17386355] - Saad Lahlou, Carlos Antônio de Barros Correia, Márcio Vasconcelos Dos Santos, Jorge Maurício David, Juceni Pereira David, Glória Pinto Duarte, Pedro Jorge Caldas Magalhães. Mechanisms underlying the cardiovascular effects of a labdenic diterpene isolated from Moldenhawera nutans in normotensive rats.
Vascular pharmacology.
2007 Jan; 46(1):60-6. doi:
10.1016/j.vph.2006.06.010. [PMID: 16875882] - Rodrigo José Bezerra de Siqueira, Pedro Jorge Caldas Magalhães, José Henrique Leal-Cardoso, Gloria Pinto Duarte, Saad Lahlou. Cardiovascular effects of the essential oil of Croton zehntneri leaves and its main constituents, anethole and estragole, in normotensive conscious rats.
Life sciences.
2006 Apr; 78(20):2365-72. doi:
10.1016/j.lfs.2005.09.042. [PMID: 16325210] - Saad Lahlou, Pedro Jorge Caldas Magalhães, Rodrigo José Bezerra de Siqueira, André Fernandes Figueiredo, Leylliane Fátima Leal Interaminense, José Guilherme Soares Maia, Pergentino José da Cunha Sousa. Cardiovascular effects of the essential oil of Aniba canelilla bark in normotensive rats.
Journal of cardiovascular pharmacology.
2005 Oct; 46(4):412-21. doi:
10.1097/01.fjc.0000175876.25296.f4. [PMID: 16160591] - Leylliane Fátima Leal Interaminense, José Henrique Leal-Cardoso, Pedro Jorge Caldas Magalhães, Gloria Pinto Duarte, Saad Lahlou. Enhanced hypotensive effects of the essential oil of Ocimum gratissimum leaves and its main constituent, eugenol, in DOCA-salt hypertensive conscious rats.
Planta medica.
2005 Apr; 71(4):376-8. doi:
10.1055/s-2005-864109. [PMID: 15856420] - Jerzy Jochem. Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2004 Apr; 369(4):418-27. doi:
10.1007/s00210-004-0883-z. [PMID: 14991226] - Saad Lahlou, Leylliane de Fátima Leal Interaminense, José Henrique Leal-Cardoso, Selene Maia Morais, Gloria Pinto Duarte. Cardiovascular effects of the essential oil of Ocimum gratissimum leaves in rats: role of the autonomic nervous system.
Clinical and experimental pharmacology & physiology.
2004 Apr; 31(4):219-25. doi:
10.1111/j.1440-1681.2004.03976.x. [PMID: 15053817] - Saad Lahlou, André Fernandes Figueiredo, Pedro Jorge Caldas Magalhães, José Henrique Leal-Cardoso, Pinto Duarte Gloria. Cardiovascular effects of methyleugenol, a natural constituent of many plant essential oils, in normotensive rats.
Life sciences.
2004 Mar; 74(19):2401-12. doi:
10.1016/j.lfs.2003.09.063. [PMID: 14998717] - Saad Lahlou, Leylliane Fátima Leal Interaminense, Pedro Jorge Caldas Magalhães, José Henrique Leal-Cardoso, Gloria Pinto Duarte. Cardiovascular effects of eugenol, a phenolic compound present in many plant essential oils, in normotensive rats.
Journal of cardiovascular pharmacology.
2004 Feb; 43(2):250-7. doi:
10.1097/00005344-200402000-00013. [PMID: 14716213] - Simonton Andrade Silveira, Nilo Resende Viana Lima, Andréa Siqueira Haibara, Cândido Celso Coimbra. The hypothalamic paraventricular nucleus and carotid receptors modulate hyperglycemia induced by hemorrhage.
Brain research.
2003 Dec; 993(1-2):183-91. doi:
10.1016/j.brainres.2003.09.013. [PMID: 14642845] - Karin Schmid, Nathalie Niederhoffer, Bela Szabo. Analysis of the respiratory effects of cannabinoids in rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2003 Oct; 368(4):301-8. doi:
10.1007/s00210-003-0787-3. [PMID: 13680088] - Saad Lahlou, Leylliane Fátima Leal Interaminense, José Henrique Leal-Cardoso, Gloria Pinto Duarte. Antihypertensive effects of the essential oil of Alpinia zerumbet and its main constituent, terpinen-4-ol, in DOCA-salt hypertensive conscious rats.
Fundamental & clinical pharmacology.
2003 Jun; 17(3):323-30. doi:
10.1046/j.1472-8206.2003.00150.x. [PMID: 12803571] - Nathalie Niederhoffer, Karin Schmid, Bela Szabo. The peripheral sympathetic nervous system is the major target of cannabinoids in eliciting cardiovascular depression.
Naunyn-Schmiedeberg's archives of pharmacology.
2003 May; 367(5):434-43. doi:
10.1007/s00210-003-0755-y. [PMID: 12709782] - Saad Lahlou, André Fernandes Figueiredo, Pedro Jorge Caldas Magalhães, José Henrique Leal-Cardoso. Cardiovascular effects of 1,8-cineole, a terpenoid oxide present in many plant essential oils, in normotensive rats.
Canadian journal of physiology and pharmacology.
2002 Dec; 80(12):1125-31. doi:
10.1139/y02-142. [PMID: 12564637] - Saad Lahlou, Charles Antonio Barros Galindo, José Henrique Leal-Cardoso, Manassés Claudino Fonteles, Gloria Pinto Duarte. Cardiovascular effects of the essential oil of Alpinia zerumbet leaves and its main constituent, Terpinen-4-ol, in rats: role of the autonomic nervous system.
Planta medica.
2002 Dec; 68(12):1097-102. doi:
10.1055/s-2002-36336. [PMID: 12494337] - S Lahlou, R F Carneiro-Leão, J H Leal-Cardoso, C F Toscano. Cardiovascular effects of the essential oil of Mentha x villosa and its main constituent, piperitenone oxide, in normotensive anaesthetised rats: role of the autonomic nervous system.
Planta medica.
2001 Oct; 67(7):638-43. doi:
10.1055/s-2001-17352. [PMID: 11582542]
