4,5Dimethyl-3-(2-oxo-2-phenyl-ethyl)-thiazole (BioDeep_00000183361)
human metabolite blood metabolite
代谢物信息卡片
化学式: C13H15NOS (233.0874)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 96%
分子结构信息
SMILES: CC1=C(C)N(CC(=O)C2=CC=CC=C2)CS1
InChI: InChI=1S/C13H15NOS/c1-10-11(2)16-9-14(10)8-13(15)12-6-4-3-5-7-12/h3-7H,8-9H2,1-2H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Martina Krautwald, Dale Leech, Stacey Horne, Megan L Steele, Josephine Forbes, Anton Rahmadi, Renate Griffith, Gerald Münch. The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase.
Rejuvenation research.
2011 Aug; 14(4):383-91. doi:
10.1089/rej.2010.1143
. [PMID: 21612515] - Aino Soro-Paavonen, Wei-Zeng Zhang, Kylie Venardos, Melinda T Coughlan, Emma Harris, David C K Tong, Daniella Brasacchio, Karri Paavonen, Jaye Chin-Dusting, Mark E Cooper, David Kaye, Merlin C Thomas, Josephine M Forbes. Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase.
Journal of hypertension.
2010 Apr; 28(4):780-8. doi:
10.1097/hjh.0b013e328335043e
. [PMID: 20186099] - Adeline L Y Tan, Karly C Sourris, Brooke E Harcourt, Vicki Thallas-Bonke, Sally Penfold, Sofianos Andrikopoulos, Merlin C Thomas, Richard C O'Brien, Angelika Bierhaus, Mark E Cooper, Josephine M Forbes, Melinda T Coughlan. Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.
American journal of physiology. Renal physiology.
2010 Mar; 298(3):F763-70. doi:
10.1152/ajprenal.00591.2009
. [PMID: 20015941] - Christos Tikellis, Merlin C Thomas, Brooke E Harcourt, Melinda T Coughlan, Josepha Pete, Katarzyna Bialkowski, Adeline Tan, Angelika Bierhaus, Mark E Cooper, Josephine M Forbes. Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.
American journal of physiology. Endocrinology and metabolism.
2008 Aug; 295(2):E323-30. doi:
10.1152/ajpendo.00024.2008
. [PMID: 18477705] - A Hoang, A J Murphy, M T Coughlan, M C Thomas, J M Forbes, R O'Brien, M E Cooper, J P F Chin-Dusting, D Sviridov. Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties.
Diabetologia.
2007 Aug; 50(8):1770-9. doi:
10.1007/s00125-007-0718-9
. [PMID: 17579831] - Mark E Cooper. Importance of advanced glycation end products in diabetes-associated cardiovascular and renal disease.
American journal of hypertension.
2004 Dec; 17(12 Pt 2):31S-38S. doi:
10.1016/j.amjhyper.2004.08.021
. [PMID: 15607433]