1-Hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylic acid methyl ester (BioDeep_00000183251)

   

human metabolite blood metabolite


代谢物信息卡片


methyl 1-hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylate

  化学式: C10H19NO3 (201.1365)
中文名称:
  谱图信息: 最多检出来源 Homo sapiens(blood) 83.63%

分子结构信息

SMILES: CC1(CC(C(N1O)(C)C)C(=O)OC)C
InChI: InChI=1S/C10H19NO3/c1-9(2)6-7(8(12)14-5)10(3,4)11(9)13/h7,13H,6H2,1-5H3


描述信息

同义名列表

6 个代谢物同义名

1-Hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylic acid methyl ester; 1-Hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylate methyl ester; Methyl 1-hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylic acid; methyl 1-hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylate; 1-Hydroxy-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidine; CM-H CPD



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Fumihiko Yoshino, Ayaka Yoshida, Naofumi Umigai, Koya Kubo, Masaichi-Chang-Il Lee. Crocetin reduces the oxidative stress induced reactive oxygen species in the stroke-prone spontaneously hypertensive rats (SHRSPs) brain. Journal of clinical biochemistry and nutrition. 2011 Nov; 49(3):182-7. doi: 10.3164/jcbn.11-01. [PMID: 22128217]
  • Ayaka Yoshida, Fumihiko Yoshino, Masahito Tsubata, Motoya Ikeguchi, Takeshi Nakamura, Masaichi-Chang-Il Lee. Direct assessment by electron spin resonance spectroscopy of the antioxidant effects of French maritime pine bark extract in the maxillofacial region of hairless mice. Journal of clinical biochemistry and nutrition. 2011 Sep; 49(2):79-86. doi: 10.3164/jcbn.10-103. [PMID: 21980222]
  • Eun-Ryeong Hahm, Michelle B Moura, Eric E Kelley, Bennett Van Houten, Sruti Shiva, Shivendra V Singh. Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species. PloS one. 2011; 6(8):e23354. doi: 10.1371/journal.pone.0023354. [PMID: 21853114]
  • A Milton Franklin Benial, Hideo Utsumi, Kazuhiro Ichikawa, Ramachandran Murugesan, Ken-ichi Yamada, Yuichi Kinoshita, Tatsuya Naganuma, Masahisa Kato. Dynamic nuclear polarization studies of redox-sensitive nitroxyl spin probes in liposomal solution. Journal of magnetic resonance (San Diego, Calif. : 1997). 2010 May; 204(1):131-8. doi: 10.1016/j.jmr.2010.02.016. [PMID: 20226702]
  • Hans-Willi Clement, Juan F Vazquez, Olaf Sommer, Philip Heiser, Henning Morawietz, Ulrich Hopt, Eberhard Schulz, Ernst von Dobschütz. Lipopolysaccharide-induced radical formation in the striatum is abolished in Nox2 gp91phox-deficient mice. Journal of neural transmission (Vienna, Austria : 1996). 2010 Jan; 117(1):13-22. doi: 10.1007/s00702-009-0327-5. [PMID: 19866338]
  • Shuichiro Araki, Yoshitaka Hirooka, Takuya Kishi, Keiji Yasukawa, Hideo Utsumi, Kenji Sunagawa. Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method. Hypertension research : official journal of the Japanese Society of Hypertension. 2009 Dec; 32(12):1091-6. doi: 10.1038/hr.2009.160. [PMID: 19763130]
  • Mayumi Yamato, Takeshi Shiba, Ken-Ichi Yamada, Toshiaki Watanabe, Hideo Utsumi. Separable detection of lipophilic- and hydrophilic-phase free radicals from the ESR spectrum of nitroxyl radical in transient MCAO mice. Free radical research. 2009 Sep; 43(9):844-51. doi: 10.1080/10715760903089716. [PMID: 19629818]
  • Abdelali Agouni, Anne-Hélène Lagrue-Lak-Hal, Hadj Ahmed Mostefai, Angela Tesse, Paul Mulder, Philippe Rouet, Franck Desmoulin, Christophe Heymes, Maria Carmen Martínez, Ramaroson Andriantsitohaina. Red wine polyphenols prevent metabolic and cardiovascular alterations associated with obesity in Zucker fatty rats (Fa/Fa). PloS one. 2009; 4(5):e5557. doi: 10.1371/journal.pone.0005557. [PMID: 19440378]
  • Takahiro Inoue, Tomomi Ide, Mayumi Yamato, Masayoshi Yoshida, Takaki Tsutsumi, Makoto Andou, Hideo Utsumi, Hiroyuki Tsutsui, Kenji Sunagawa. Time-dependent changes of myocardial and systemic oxidative stress are dissociated after myocardial infarction. Free radical research. 2009 Jan; 43(1):37-46. doi: 10.1080/10715760802534820. [PMID: 19048435]
  • Hannes P Neeff, Ernst von Dobschuetz, Olaf Sommer, Ulrich T Hopt, Oliver Drognitz. In vivo quantification of oxygen-free radical release in experimental pancreas transplantation. Transplant international : official journal of the European Society for Organ Transplantation. 2008 Nov; 21(11):1081-9. doi: 10.1111/j.1432-2277.2008.00740.x. [PMID: 18699844]
  • Kyo Kobayashi, Fumihiko Yoshino, Shun-Suke Takahashi, Kazuo Todoki, Yojiro Maehata, Tomoko Komatsu, Kazu-Ichi Yoshida, Masaichi-Chang-Il Lee. Direct assessments of the antioxidant effects of propofol medium chain triglyceride/long chain triglyceride on the brain of stroke-prone spontaneously hypertensive rats using electron spin resonance spectroscopy. Anesthesiology. 2008 Sep; 109(3):426-35. doi: 10.1097/aln.0b013e318182a903. [PMID: 18719440]
  • A Semmelmann, H Neeff, O Sommer, O Thomusch, U T Hopt, E von Dobschuetz. Evaluation of preservation solutions by ESR-spectroscopy: superior effects of University of Wisconsin over Histidine-Tryptophan-Ketoglutarate in reducing renal reactive oxygen species. Kidney international. 2007 May; 71(9):875-81. doi: 10.1038/sj.ki.5002129. [PMID: 17311072]
  • Ken-ichi Yamada, Ikuo Yamamiya, Hideo Utsumi. In vivo detection of free radicals induced by diethylnitrosamine in rat liver tissue. Free radical biology & medicine. 2006 Jun; 40(11):2040-6. doi: 10.1016/j.freeradbiomed.2006.01.031. [PMID: 16716904]
  • Nermin Kuzkaya, Norbert Weissmann, David G Harrison, Sergey Dikalov. Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase. Biochemical pharmacology. 2005 Aug; 70(3):343-54. doi: 10.1016/j.bcp.2005.05.009. [PMID: 15963955]