N,N'-Dichloro-N,N'-diphenylmethanediamine (BioDeep_00000183240)
human metabolite blood metabolite
代谢物信息卡片
化学式: C13H12Cl2N2 (266.0377492)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)N(CN(C2=CC=CC=C2)Cl)Cl
InChI: InChI=1S/C13H12Cl2N2/c14-16(12-7-3-1-4-8-12)11-17(15)13-9-5-2-6-10-13/h1-10H,11H2
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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Plant Reactome(0)
INOH(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- C Keen, M Coldwell, K McNally, P Baldwin, J McAlinden, J Cocker. A follow up study of occupational exposure to 4,4'-methylene-bis(2-chloroaniline) (MbOCA) and isocyanates in polyurethane manufacture in the UK.
Toxicology letters.
2012 Aug; 213(1):3-8. doi:
10.1016/j.toxlet.2011.04.003. [PMID: 21501672] - Abid Dost, J K Straughan, Tom Sorahan. Cancer incidence and exposure to 4,4'-methylene-bis-ortho-chloroaniline (MbOCA).
Occupational medicine (Oxford, England).
2009 Sep; 59(6):402-5. doi:
10.1093/occmed/kqp093. [PMID: 19564173] - J Cocker, J R Cain, P Baldwin, K McNally, K Jones. A survey of occupational exposure to 4,4'-methylene-bis (2-chloroaniline) (MbOCA) in the UK.
The Annals of occupational hygiene.
2009 Jul; 53(5):499-507. doi:
10.1093/annhyg/mep026. [PMID: 19447850] - Hong-I Chen, Saou-Hsing Liou, Shu-Fen Ho, Kuen-Yuh Wu, Chien-Wen Sun, Ming-Fong Chen, Li-Chuan Cheng, Tung-Sheng Shih, Ching-Hui Loh. Oxidative DNA damage estimated by plasma 8-hydroxydeoxyguanosine (8-OHdG): influence of 4, 4'-methylenebis (2-chloroaniline) exposure and smoking.
Journal of occupational health.
2007 Sep; 49(5):389-98. doi:
10.1539/joh.49.389. [PMID: 17951971] - J Cocker, K Jones, J Morton, H J Mason. Biomonitoring at the UK Health and Safety Laboratory.
International journal of hygiene and environmental health.
2007 May; 210(3-4):383-6. doi:
10.1016/j.ijheh.2007.01.028. [PMID: 17321210] - Wei-Chung Shih, Ming-Feng Chen, Chih-Chun Jean Huang, Shi-Nian Uang, Tung-Shen Shih, Saou-Hsing Liou, Kuen-Yuh Wu. Simultaneous analysis of urinary 4,4'-methylenebis(2-chloroaniline) and N-acetyl 4,4'-methylenebis(2-chloroaniline) using solid-phase extraction and liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2007; 21(24):4073-8. doi:
10.1002/rcm.3314. [PMID: 18008389] - Hong-I Chen, Saou-Hsing Liou, Ching-Hui Loh, Shi-Nian Uang, Yi-Chun Yu, Tung-Sheng Shih. Bladder cancer screening and monitoring of 4,4'-methylenebis(2-chloroaniline) exposure among workers in Taiwan.
Urology.
2005 Aug; 66(2):305-10. doi:
10.1016/j.urology.2005.02.031. [PMID: 16098360] - E B Murray, J W Edwards. Differential induction of micronuclei in peripheral lymphocytes and exfoliated urothelial cells of workers exposed to 4,4'-methylenebis-(2-chloroaniline) (MOCA) and bitumen fumes.
Reviews on environmental health.
2005 Jul; 20(3):163-76. doi:
10.1515/reveh.2005.20.3.163. [PMID: 16335575]