2-(5-Hydroxy-1H-indol-2-yl)acetic acid (BioDeep_00000183237)

   

human metabolite blood metabolite


代谢物信息卡片


2-(5-Hydroxy-1H-indol-2-yl)acetic acid

化学式: C10H9NO3 (191.0582404)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 34.78%

分子结构信息

SMILES: C1=CC2=C(C=C1O)C=C(N2)CC(=O)O
InChI: InChI=1S/C10H9NO3/c12-8-1-2-9-6(4-8)3-7(11-9)5-10(13)14/h1-4,11-12H,5H2,(H,13,14)

描述信息

同义名列表

3 个代谢物同义名

2-(5-Hydroxy-1H-indol-2-yl)acetic acid; (5-hydroxy-1H-indol-2-yl)acetic acid; 2-(5-Hydroxy-1H-indol-2-yl)acetate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • C Alberti. Revisiting the retroperitoneal fibroses: are there any significant news about their aetiopathogenesis and diagnostic approaches?. European review for medical and pharmacological sciences. 2012 Aug; 16(8):1078-94. doi: NULL. [PMID: 22913159]
  • Emmanouil Hatzipantelis, Paraskevi Panagopoulou, Vasiliki Sidi-Fragandrea, Ioanna Fragandrea, Dimitrios E Koliouskas. Carcinoid tumors of the appendix in children: experience from a tertiary center in northern Greece. Journal of pediatric gastroenterology and nutrition. 2010 Nov; 51(5):622-5. doi: 10.1097/mpg.0b013e3181e05358. [PMID: 20948448]
  • Maria Addolorata Saracino, Gilberto Gerra, Lorenzo Somaini, Marco Colombati, Maria Augusta Raggi. Chromatographic analysis of serotonin, 5-hydroxyindolacetic acid and homovanillic acid in dried blood spots and platelet poor and rich plasma samples. Journal of chromatography. A. 2010 Jul; 1217(29):4808-14. doi: 10.1016/j.chroma.2010.05.031. [PMID: 20554289]
  • Shinsuke Sasada, Yasutomo Ojima, Masahiko Nishizaki, Masao Harano, Hiroyoshi Matsukawa, Hideki Aoki, Shigehiro Shiozaki, Satoshi Ohno, Motoki Ninomiya, Hiroo Matsuura, Norihisa Takakura. Well-differentiated endocrine cell carcinoma of ileum treated by laparoscopy-assisted surgery--a case report. Hiroshima journal of medical sciences. 2010 Jun; 59(2):35-8. doi: NULL. [PMID: 20632686]
  • M Bernabé Durán, M M Molinero, E Briceño-García, J Vicente-Romo. [Primary renal carcinoid tumor]. Radiologia. 2010 Mar; 52(2):167-70. doi: 10.1016/j.rx.2009.12.001. [PMID: 20170932]
  • M A Gilinsky, T V Latysheva, G M Petrakova. Dimethylarginines and serotonin in the blood of spontaneously hypertensive rats. Bulletin of experimental biology and medicine. 2009 Dec; 148(6):849-51. doi: 10.1007/s10517-010-0833-3. [PMID: 21116488]
  • Misaki Wayengera. Searching for new clues about the molecular cause of endomyocardial fibrosis by way of in silico proteomics and analytical chemistry. PloS one. 2009 Oct; 4(10):e7420. doi: 10.1371/journal.pone.0007420. [PMID: 19823676]
  • D I Nasyrova, N A Urtikova, A Ia Sapronova, M V Ugriumov. [Brain is a source of blood serotonin in rats during perinatal development]. Ontogenez. 2009 Jan; 40(1):55-64. doi: NULL. [PMID: 19326844]
  • Razina R Nigmatullina, Venera V Kirillova, Roen K Jourjikiya, Marat A Mukhamedyarov, Vladimir S Kudrin, Petr M Klodt, András Palotás. Disrupted serotonergic and sympathoadrenal systems in patients with chronic heart failure may serve as new therapeutic targets and novel biomarkers to assess severity, progression and response to treatment. Cardiology. 2009; 113(4):277-86. doi: 10.1159/000205962. [PMID: 19270454]
  • Z El Ali, E Szczepanek, P Majewski, K Iwanik, J Sowinski, M Grzymislawski. Single brain metastasis from a minute, well differentiated, but invading beyond the tunica muscularis mucosa rectal carcinoid. Acta gastro-enterologica Belgica. 2009 Jan; 72(1):63-6. doi: NULL. [PMID: 19402375]
  • Ioannis Ilias, Karel Pacak. A clinical overview of pheochromocytomas/paragangliomas and carcinoid tumors. Nuclear medicine and biology. 2008 Aug; 35 Suppl 1(?):S27-34. doi: 10.1016/j.nucmedbio.2008.04.007. [PMID: 18707631]
  • Jeong Won Jahng, Nam Youl Kim, Vitaly Ryu, Sang Bae Yoo, Bom-Taeck Kim, Dong-Won Kang, Jong-Ho Lee. Dexamethasone reduces food intake, weight gain and the hypothalamic 5-HT concentration and increases plasma leptin in rats. European journal of pharmacology. 2008 Feb; 581(1-2):64-70. doi: 10.1016/j.ejphar.2007.11.029. [PMID: 18164702]
  • Veit Roessner, Susanne Walitza, Franz Riederer, Regina Hünnerkopf, Aribert Rothenberger, Manfred Gerlach, Andreas Moser. Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD?. Behavioral and brain functions : BBF. 2007 Dec; 3(?):64. doi: 10.1186/1744-9081-3-64. [PMID: 18070346]
  • Sheng-hong Zhou, Fu-dong Wu. [Therapeutic effect of acupuncture on female's climacteric depression and its effects on DA, NE and 5-HIAA contents]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 2007 May; 27(5):317-21. doi: ". [PMID: 17645249]
  • Christos Toumpanakis, Richard A Standish, Elora Baishnab, Mark C Winslet, Martyn E Caplin. Goblet cell carcinoid tumors (adenocarcinoid) of the appendix. Diseases of the colon and rectum. 2007 Mar; 50(3):315-22. doi: 10.1007/s10350-006-0762-4. [PMID: 17195086]
  • Ashley B Grossman, Philip Kelly, Andrea Rockall, Satya Bhattacharya, Ann McNicol, Tara Barwick, Tara Balwick. Cushing's syndrome caused by an occult source: difficulties in diagnosis and management. Nature clinical practice. Endocrinology & metabolism. 2006 Nov; 2(11):642-7. doi: 10.1038/ncpendmet0327. [PMID: 17082811]
  • Kornélia Tekes, Mónika Hantos, György Bátor, Melinda Gyenge, Rudolf Laufer, András Folyovich. [Endogenous nociceptin level in ischemic stroke: connection to serotonin system]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. 2006 Jun; 8(2):53-9. doi: NULL. [PMID: 17073212]
  • Jose E Abdenur, Nico Abeling, Norma Specola, Lia Jorge, Andrea B Schenone, Arno C van Cruchten, Nestor A Chamoles. Aromatic l-aminoacid decarboxylase deficiency: unusual neonatal presentation and additional findings in organic acid analysis. Molecular genetics and metabolism. 2006 Jan; 87(1):48-53. doi: 10.1016/j.ymgme.2005.09.007. [PMID: 16288991]
  • W W de Herder. Tumours of the midgut (jejunum, ileum and ascending colon, including carcinoid syndrome). Best practice & research. Clinical gastroenterology. 2005 Oct; 19(5):705-15. doi: 10.1016/j.bpg.2005.05.007. [PMID: 16253895]
  • Jonathan E Prousky. Pellagra may be a rare secondary complication of anorexia nervosa: a systematic review of the literature. Alternative medicine review : a journal of clinical therapeutic. 2003 May; 8(2):180-5. doi: NULL. [PMID: 12777163]
  • Tahira Perveen, Syeda Farheen Zehra, Saida Haider, Naheed Akhtar, Darakhshan J Haleem. Effects of 2 hrs. restraint stress on brain serotonin metabolism and memory in rats. Pakistan journal of pharmaceutical sciences. 2003 Jan; 16(1):27-33. doi: NULL. [PMID: 16414564]
  • E Hernández, S Lastra, M Urbina, I Carreira, L Lima. Serotonin, 5-hydroxyindoleacetic acid and serotonin transporter in blood peripheral lymphocytes of patients with generalized anxiety disorder. International immunopharmacology. 2002 Jun; 2(7):893-900. doi: 10.1016/s1567-5769(02)00025-5. [PMID: 12188031]
  • M Wilhelmi, M K H Fritz, S Fischer, A Haverich, W Harringer. Triple valve replacement in a patient with severe carcinoid heart disease. Cardiovascular surgery (London, England). 2002 Jun; 10(3):287-90. doi: 10.1016/s0967-2109(01)00137-5. [PMID: 12044440]
  • Akira Kusaga. [Decreased beta-phenylethylamine in urine of children with attention deficit hyperactivity disorder and autistic disorder]. No to hattatsu = Brain and development. 2002 May; 34(3):243-8. doi: NULL. [PMID: 12030014]
  • W Fiebiger, M Penz, F Längle, A Kurtaran, G Oberhuber, M Raderer. Malignancy in slow motion: diagnosis of biochemically apparent, but otherwise occult persistent disease 21 years after resection of a carcinoid tumour of the terminal ileum. Scandinavian journal of gastroenterology. 2001 Oct; 36(10):1116-8. doi: 10.1080/003655201750422756. [PMID: 11589388]
  • P R Baker, T N Calvey, K Chan, C M Macnee, K Taylor. Plasma clearance of neostigmine and pyridostigmine in the dog. British journal of pharmacology. 1978 Jul; 63(3):509-12. doi: 10.1111/j.1476-5381.1978.tb07805.x. [PMID: 667495]