2-Hydroxy-5-oxohexanedioic acid (BioDeep_00000183236)

   

human metabolite blood metabolite


代谢物信息卡片


2-Hydroxy-5-oxohexanedioic acid

化学式: C6H8O6 (176.0320868)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 22.22%

分子结构信息

SMILES: C(CC(=O)C(=O)O)C(C(=O)O)O
InChI: InChI=1S/C6H8O6/c7-3(5(9)10)1-2-4(8)6(11)12/h3,7H,1-2H2,(H,9,10)(H,11,12)

描述信息

同义名列表

2 个代谢物同义名

2-Hydroxy-5-oxohexanedioic acid; 2-Hydroxy-5-oxohexanedioate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Marià Alemany. Utilization of dietary glucose in the metabolic syndrome. Nutrition & metabolism. 2011 Oct; 8(1):74. doi: 10.1186/1743-7075-8-74. [PMID: 22029632]
  • Roberto Conti, Edoardo Mannucci, Pompeo Pessotto, Emanuela Tassoni, Paolo Carminati, Fabio Giannessi, Arduino Arduini. Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis. Diabetes. 2011 Feb; 60(2):644-51. doi: 10.2337/db10-0346. [PMID: 21270274]
  • Annelies Peeters, Myriam Baes. Role of PPARα in Hepatic Carbohydrate Metabolism. PPAR research. 2010; 2010(?):. doi: 10.1155/2010/572405. [PMID: 20936117]
  • João M N Duarte, Florence D Morgenthaler, Hongxia Lei, Carol Poitry-Yamate, Rolf Gruetter. Steady-state brain glucose transport kinetics re-evaluated with a four-state conformational model. Frontiers in neuroenergetics. 2009; 1(?):6. doi: 10.3389/neuro.14.006.2009. [PMID: 20027232]
  • Tunahan Cakir, Selma Alsan, Hale Saybaşili, Ata Akin, Kutlu O Ulgen. Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. Theoretical biology & medical modelling. 2007 Dec; 4(?):48. doi: 10.1186/1742-4682-4-48. [PMID: 18070347]
  • Naoki Shiota, Masayuki Shimono, Shiho Tomioka, Kenichi Takano, Ayako Kato, Akihiro Kawakami, Takehiro Ishizuka. [A boy with nystagmus, refractory dystonia and apneic attack due to alternating hemiplegia of childhood]. No to hattatsu = Brain and development. 2007 Jul; 39(4):285-8. doi: . [PMID: 17633086]
  • Nathalie Folch, François Péronnet, Michel Péan, Denis Massicotte, Carole Lavoie. Labeled CO(2) production and oxidative vs nonoxidative disposal of labeled carbohydrate administered at rest. Metabolism: clinical and experimental. 2005 Nov; 54(11):1428-34. doi: 10.1016/j.metabol.2005.05.006. [PMID: 16253629]
  • Lui G Forni, William McKinnon, Gwyn A Lord, David F Treacher, Jean-Marie R Peron, Philip J Hilton. Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis. Critical care (London, England). 2005 Oct; 9(5):R591-5. doi: 10.1186/cc3806. [PMID: 16277723]
  • Hye-soo Kim, Gab-sang Lee, Sang-hwan Hyun, So-hyun Lee, Dong-hyun Nam, Yeon-woo Jeong, Sue Kim, Sung-keun Kang, Byeong-chun Lee, Woo-suk Hwang. Improved in vitro development of porcine embryos with different energy substrates and serum. Theriogenology. 2004 May; 61(7-8):1381-93. doi: 10.1016/j.theriogenology.2003.08.012. [PMID: 15036970]
  • John P M Wood, Glyn Chidlow, Mark Graham, Neville N Osborne. Energy substrate requirements of rat retinal pigmented epithelial cells in culture: relative importance of glucose, amino acids, and monocarboxylates. Investigative ophthalmology & visual science. 2004 Apr; 45(4):1272-80. doi: 10.1167/iovs.03-0693. [PMID: 15037596]
  • F N Gil'miiarova, Iu V Pervova, V M Radomskaia, N I Gergel', S V Tarasova. [Levels of unified metabolites and thyroid hormones in blood and oral fluid of children with minimal brain dysfunction]. Biomeditsinskaia khimiia. 2004 Mar; 50(2):204-10. doi: NULL. [PMID: 15179829]
  • Carmen de Mendoza, Francisco Blanco, Vicente Soriano. [Mitochondrial damage by antiretrovirals: diagnosis and monitoring]. Medicina clinica. 2003 Sep; 121(8):310-5. doi: 10.1016/s0025-7753(03)73926-8. [PMID: 14499088]
  • Otto Clemmesen. Splanchnic circulation and metabolism in patients with acute liver failure. Danish medical bulletin. 2002 Aug; 49(3):177-93. doi: NULL. [PMID: 12238280]