[6-Hydroxy-8-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-4-yl]methyl benzoate (BioDeep_00000183225)
human metabolite blood metabolite
代谢物信息卡片
(6-hydroxy-8-methyl-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dioxatetracyclo[4.3.1.0^{2,5}.0^{3,8}]decan-4-yl)methyl benzoate
化学式: C23H28O11 (480.16315380000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CC3(C4C(C1(C4C(O2)O3)OC5C(C(C(C(O5)CO)O)O)O)COC(=O)C6=CC=CC=C6)O
InChI: InChI=1S/C23H28O11/c1-21-9-22(29)13-11(8-30-18(28)10-5-3-2-4-6-10)23(21,14(13)19(32-21)33-22)34-20-17(27)16(26)15(25)12(7-24)31-20/h2-6,11-17,19-20,24-27,29H,7-9H2,1H3
描述信息
同义名列表
4 个代谢物同义名
(6-hydroxy-8-methyl-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dioxatetracyclo[4.3.1.0^{2,5}.0^{3,8}]decan-4-yl)methyl benzoate; [6-Hydroxy-8-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-4-yl]methyl benzoic acid; (6-Hydroxy-8-methyl-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-9,10-dioxatetracyclo[4.3.1.0,.0,]decan-4-yl)methyl benzoic acid; [6-Hydroxy-8-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-4-yl]methyl benzoate
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Biomedical chromatography : BMC.
2012 Jul; 26(7):816-25. doi:
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Archives of pharmacal research.
2012 Jan; 35(1):101-8. doi:
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Biomedical chromatography : BMC.
2012 Jan; 26(1):26-32. doi:
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2011 Nov; 16(11):9600-10. doi:
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2011 Oct; 25(10):1551-7. doi:
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Chinese medical journal.
2011 Oct; 124(19):3105-11. doi:
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Parasitology.
2011 Sep; 138(10):1259-71. doi:
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Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control.
2011 Jun; 23(3):288-91. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2011 Jun; 36(11):1508-11. doi:
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Canadian journal of physiology and pharmacology.
2011 Jun; 89(6):445-53. doi:
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Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases.
2011 Apr; 29(2):93-8. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2011 Apr; 36(8):1015-8. doi:
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Fitoterapia.
2011 Apr; 82(3):466-73. doi:
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2011 Mar; 12(3):193-200. doi:
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International immunopharmacology.
2011 Feb; 11(2):172-8. doi:
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Journal of ethnopharmacology.
2011 Jan; 133(2):735-42. doi:
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Asian Pacific journal of cancer prevention : APJCP.
2011; 12(8):2031-7. doi:
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Frontiers in pharmacology.
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2011 Jan; 7(25):4-8. doi:
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Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2010 Dec; 33(12):1904-8. doi:
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Biomedical chromatography : BMC.
2010 Dec; 24(12):1324-31. doi:
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2010 Nov; 33(11):1768-70. doi:
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Fitoterapia.
2010 Sep; 81(6):662-7. doi:
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Journal of ethnopharmacology.
2010 Jul; 130(2):407-13. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2010 Jun; 35(11):1490-3. doi:
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2010 May; 35(9):1193-6. doi:
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2010 Apr; 45(4):489-93. doi:
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Archives of pharmacal research.
2010 Apr; 33(4):619-23. doi:
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2010 Jan; 35(2):208-10. doi:
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Yao xue xue bao = Acta pharmaceutica Sinica.
2010 Jan; 45(1):37-42. doi:
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The Journal of parasitology.
2009 Dec; 95(6):1520-4. doi:
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Journal of ethnopharmacology.
2009 Nov; 126(2):244-51. doi:
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Journal of ethnopharmacology.
2009 Sep; 125(3):444-9. doi:
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Phytochemical analysis : PCA.
2009 Sep; 20(5):385-94. doi:
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Journal of ethnopharmacology.
2009 Jul; 124(2):316-20. doi:
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Basic & clinical pharmacology & toxicology.
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
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Journal of AOAC International.
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Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
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Life sciences.
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Journal of pharmaceutical and biomedical analysis.
2009 Feb; 49(2):253-66. doi:
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The Journal of pharmacy and pharmacology.
2009 Feb; 61(2):213-9. doi:
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Journal of pharmaceutical and biomedical analysis.
2008 Dec; 48(5):1462-6. doi:
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Journal of pharmaceutical and biomedical analysis.
2008 Dec; 48(4):1261-6. doi:
10.1016/j.jpba.2008.09.011. [PMID: 18930621] - Shu-Lan Su, Li Yu, Yong-Qing Hua, Jin-Ao Duan, Hai-Shan Deng, Yu-Ping Tang, Yin Lu, An-Wei Ding. Screening and analyzing the potential bioactive components from Shaofu Zhuyu decoction, using human umbilical vein endothelial cell extraction and high-performance liquid chromatography coupled with mass spectrometry.
Biomedical chromatography : BMC.
2008 Dec; 22(12):1385-92. doi:
10.1002/bmc.1070. [PMID: 18655214] - Jie Wu, Nan Yao, Da-Wei Wang. [Determination of paeoniflorin in rat plasma by HPLC-MS/MS and its pharmacokinetics].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Oct; 33(20):2369-73. doi:
NULL. [PMID: 19157131] - Li-Rong Sun, Xiong Cao, Feng-Qing Hou, Xin-Hong Zhu, Tian-Ming Gao. [Progressive studies of paeoniflorin].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Sep; 33(18):2028-32. doi:
". [PMID: 19160776] - Gang Zhou, Qing-Hong Lv. [Studies on content determination and fingerprint of active constituents in different parts of cortex moutan].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Sep; 33(18):2070-3. doi:
". [PMID: 19160786] - Qiao-ru Li, Wen-hui Song, Jiang-ping Lian, Pen Zhang, Yan Zuo, Bo Zhao. [Study of using shattering extraction with solvent to extract ingredient of three kinds of traditional Chinese medicine].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Jun; 33(12):1393-5. doi:
". [PMID: 18837338] - Chang-Hong Wang, Rui Wang, Xue-Mei Cheng, Yu-Qi He, Zheng-Tao Wang, Cheng Wu, Jing Cao. Comparative pharmacokinetic study of paeoniflorin after oral administration of decoction of Radix Paeoniae Rubra and Radix Paeoniae Alba in rats.
Journal of ethnopharmacology.
2008 May; 117(3):467-72. doi:
10.1016/j.jep.2008.02.035. [PMID: 18424022] - Mamoru Okasaka, Yoshiki Kashiwada, Olimjon K Kodzhimatov, Ozodbek Ashurmetov, Yoshihisa Takaishi. Monoterpene glycosides from Paeonia hybrida.
Phytochemistry.
2008 May; 69(8):1767-72. doi:
10.1016/j.phytochem.2008.02.016. [PMID: 18400238] - Bomi Lee, Yong-Wook Shin, Eun-Ah Bae, San-Jun Han, Joo-Sun Kim, Sam-Sik Kang, Dong-Hyun Kim. Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonol.
Archives of pharmacal research.
2008 Apr; 31(4):445-50. doi:
10.1007/s12272-001-1177-6. [PMID: 18449501] - Xiao-yan Han, Zheng-an Liu, Liang-sheng Wang. [Comparison of the content of effective components between tree peony wild species and main cultivars].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2008 Mar; 31(3):327-31. doi:
". [PMID: 18619232] - Xue-Feng Feng, Shi-Lin Hu, Yong-Xin Zhang, Yan He, Qi-Wei Zhang, Xiao-Guang Ge, Jing-Yu Yang. [Dynamic change of paeoniflorin content in root of Paeonia lactiflora growing at Duolun County, Inner Mongolia].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2008 Feb; 33(3):244-7. doi:
". [PMID: 18536456] - Alessandra Braca, Phan Van Kiem, Pham Hai Yen, Nguyen Xuan Nhiem, Tran Hong Quang, Nguyen Xuan Cuong, Chau Van Minh. New monoterpene glycosides from Paeonia lactiflora.
Fitoterapia.
2008 Feb; 79(2):117-20. doi:
10.1016/j.fitote.2007.11.001. [PMID: 18201840] - Irina Tsoy Nizamutdinova, Yong Chun Jin, Ju Sun Kim, Min Hye Yean, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Hye Jung Kim, Ki Churl Chang. Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats.
Planta medica.
2008 Jan; 74(1):14-8. doi:
10.1055/s-2007-993775. [PMID: 18203054] - Li-yan Zhou, Sheng-wang Liang, Shu-mei Wang, A-li Chen, Li-jiao Fu. [The quality control of carbonized cortex moutan].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2007 Dec; 30(12):1502-5. doi:
". [PMID: 18422180] - Junbo Xie, Wenquan Wang, Yanqing Zhang, Yin Bai, Quan Yang. Simultaneous analysis of glycyrrhizin, paeoniflorin, quercetin, ferulic acid, liquiritin, formononetin, benzoic acid and isoliquiritigenin in the Chinese proprietary medicine Xiao Yao Wan by HPLC.
Journal of pharmaceutical and biomedical analysis.
2007 Nov; 45(3):450-5. doi:
10.1016/j.jpba.2007.07.011. [PMID: 17709224] - Yin Chen, Wei Wei, Hong Wu, Ling-ling Zhang, Jing-yu Chen. [Effects of paeoniflorin on the level of antibodies and cAMP produced by splenocytes in rats with adjuvant arthritis].
Yao xue xue bao = Acta pharmaceutica Sinica.
2007 Nov; 42(11):1147-51. doi:
NULL. [PMID: 18300469] - Pham Hai Yen, Phan Van Kiem, Nguyen Xuan Nhiem, Nguyen Huu Tung, Tran Hong Quang, Chau Van Minh, Jung Woo Kim, Eun Mi Choi, Young Ho Kim. A new monoterpene glycoside from the roots of Paeonia lactiflora increases the differentiation of osteoblastic MC3T3-E1 cells.
Archives of pharmacal research.
2007 Oct; 30(10):1179-85. doi:
10.1007/bf02980258. [PMID: 18038896] - Su-Mei Xia, Rong Shen, Xue-Ying Sun, Li-Li Shen, Yi-Ming Yang, Ying Ke, Yun Wang, Dong-Ying Chen, Xing-Mei Han. Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the determination of paeoniflorin in rat brain and its application to pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Sep; 857(1):32-9. doi:
10.1016/j.jchromb.2007.06.022. [PMID: 17631428] - Lianyu Guo, So Yean Cho, Sam Sik Kang, Seung-Ho Lee, Hum-Young Baek, Yeong Shik Kim. Orthogonal array design for optimizing extraction efficiency of active constituents from Jakyak-Gamcho Decoction, the complex formula of herbal medicines, Paeoniae Radix and Glycyrrhizae Radix.
Journal of ethnopharmacology.
2007 Sep; 113(2):306-11. doi:
10.1016/j.jep.2007.06.013. [PMID: 17681441] - Liang Zhang, De-sheng Xu, Yi Feng. [Study on adscription of plasma effective constituents of rat after administrated with Paeonia lacliflora and Glycyrrhiza uralensis compound].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2007 Sep; 32(17):1789-91. doi:
NULL. [PMID: 17993004] - Ju-Xiu He, Emi Goto, Teruaki Akao, Tadato Tani. Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2007 Aug; 14(7-8):452-9. doi:
10.1016/j.phymed.2006.09.014. [PMID: 17097282] - Jun-an Fan, Yan Zhang, Yong-peng Xia, Zong-yin Qiu, Chao Yu, Ji-sheng Wang, Bin-hao Wang. [Dynamic analysis of major active ingredients of Cortex Moutan cultivated in Dianjiang county of Chongqing].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2007 Aug; 32(15):1501-4. doi:
". [PMID: 17972572] - Zhi-xin Yang, Guang-jie Pei, Yong-ji Li, Yan-hong Wang, Rui Wang, Jun Liu. [Separation and refine of Xiaoyao Pill by macroporous adsorption resin].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2007 Jun; 32(12):1164-7. doi:
". [PMID: 17802877] - Y-Q Zheng, W Wei, L Zhu, J-X Liu. Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2007 May; 56(5):182-8. doi:
10.1007/s00011-006-6002-5. [PMID: 17588133] - Chun Rong Li, Zhe Zhou, Dan Zhu, Yu Ning Sun, Jin Ming Dai, Sheng Qi Wang. Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases.
The international journal of biochemistry & cell biology.
2007; 39(2):426-38. doi:
10.1016/j.biocel.2006.09.011. [PMID: 17097910] - Liu Yang, Shun-Jun Xu, Run-Tao Tian, Pei-Shan Xie, Zheng-Tao Wang. [HPLC fingerprinting of radix paeoniae alba].
Yao xue xue bao = Acta pharmaceutica Sinica.
2007 Jan; 42(1):71-4. doi:
". [PMID: 17520811] - Chunai Cao, Xihui He, Wei Wang, Lujun Zhang, Han Lin, Lijun Du. Kinetic distribution of paeoniflorin in cortex of normal and cerebral ischemia-reperfusion rats after intravenous administration of Paeoniae Radix extract.
Biomedical chromatography : BMC.
2006 Dec; 20(12):1283-8. doi:
10.1002/bmc.658. [PMID: 17006964] - Nobuaki Hirai, Kazuyuki Ishikawa, Koichi Takahashi. Improvement of the agitation granulation method to prepare granules containing a high content of a very hygroscopic drug.
The Journal of pharmacy and pharmacology.
2006 Nov; 58(11):1437-41. doi:
10.1211/jpp.58.11.0003. [PMID: 17132205] - Dong-Mei Chen, Liang Xiao, Xin Cai, Rong Zeng, Xing-Zu Zhu. Involvement of multitargets in paeoniflorin-induced preconditioning.
The Journal of pharmacology and experimental therapeutics.
2006 Oct; 319(1):165-80. doi:
10.1124/jpet.106.104380. [PMID: 16840647] - Yu-Wen Wang, Ke Yu, Yi-Yu Cheng. [Simultaneous determination of three active constituents in cortex moutan by RP-HPLC].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Oct; 31(20):1699-701. doi:
". [PMID: 17225540] - Li Zhang, Yi Dong, Yang Sun, Ting Chen, Qiang Xu. Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice.
The Journal of pharmacy and pharmacology.
2006 Sep; 58(9):1257-64. doi:
10.1211/jpp.58.9.0013. [PMID: 16945185] - Qiao Wang, Rong-Xia Liu, Hong-Zhu Guo, Zhong-Ning Zhu, Kai-Shun Bi, De-An Guo. [Study on influence of processing methods on chemical constituents in Radix Paeoniae Alba].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Sep; 31(17):1418-21. doi:
. [PMID: 17087079] - Ya-jun Zhang, Lian-ying Xu. [Study on purification of Radix Paeoniae Alba by HPD100 macroporous resin].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2006 Sep; 29(9):968-70. doi:
". [PMID: 17212057] - Yan He, Hui-dong Zhao, Li-ying Tang, Zhu-ju Wang, Qi-wei Zhang. [Study on quality control of Paeonia lactiflora].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Jul; 31(13):1070-1. doi:
". [PMID: 17048604] - Patricia Y Hayes, Reg Lehmann, Kerry Penman, Kerry M Bone, William Kitching, James J De Voss. RP-HPLC detection of a sulphiting-induced artefact from paeoniflorin in dried roots of Paeonia lactiflora.
Phytochemical analysis : PCA.
2006 Jul; 17(4):251-4. doi:
10.1002/pca.911. [PMID: 16910041] - Yan He, Hui-dong Zhao, Bei-xiang He, Li-ying Tang, Qi-wei Zhang, Zhu-ju Wang. [Experimental study on processing of Paeonia lactiflora].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2006 Jun; 31(11):889-91. doi:
". [PMID: 17048625] - Xing-Gang Yang, Bo Peng, Guo-Hua Zhang, Lan-Lan Wei, Shu-Fang Nie, Wei-San Pan. Studies of the pharmacokinetics of paeoniflorin in two Jing-Zhi-Guan-Xin formulations after oral administration to beagle dogs.
Journal of pharmaceutical and biomedical analysis.
2006 Apr; 41(1):320-4. doi:
10.1016/j.jpba.2005.11.004. [PMID: 16377116] - Xing-Gang Yang, Guo-Hua Zhang, Wei Li, Bo Peng, Zhi-Dong Liu, Wei-San Pan. Design and evaluation of jingzhiguanxin monolithic osmotic pump tablet.
Chemical & pharmaceutical bulletin.
2006 Apr; 54(4):465-9. doi:
10.1248/cpb.54.465. [PMID: 16595946] - Dao-Fang Liu, Wei Wei, Li-Hua Song. Protective effect of paeoniflorin on immunological liver injury induced by bacillus Calmette-Guerin plus lipopolysaccharide: modulation of tumour necrosis factor-alpha and interleukin-6 MRNA.
Clinical and experimental pharmacology & physiology.
2006 Apr; 33(4):332-9. doi:
10.1111/j.1440-1681.2006.04371.x. [PMID: 16620297]