3-Amino-2-oxazolidone (BioDeep_00000018321)
human metabolite Endogenous blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: C3H6N2O2 (102.04292559999999)
中文名称: 3-氨基-2-噁唑烷酮(AOZ), 3-氨基-2-恶唑烷酮
谱图信息:
最多检出来源 Homo sapiens(blood) 38.89%
分子结构信息
SMILES: C1COC(=O)N1N
InChI: InChI=1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2
描述信息
3-Amino-2-oxazolidone is a metabolite of furazolidone. Furazolidone is a nitrofuran antibacterial. It is marketed by Roberts Laboratories under the brand name Furoxone and by GlaxoSmithKline as Dependal-M. (Wikipedia)
D000890 - Anti-Infective Agents > D023303 - Oxazolidinones
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jinyan Gong, Jiong Li, Haina Yuan, Bingquan Chu, Weijie Lin, Qingwen Cao, Qiqi Zhao, Ruosi Fang, Ling Li, Gongnian Xiao. Determination of four nitrofuran metabolites in gelatin Chinese medicine using dispersive solid phase extraction and pass-through solid phase extraction coupled to ultra high performance liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Jun; 1146(?):122018. doi:
10.1016/j.jchromb.2020.122018. [PMID: 32334390] - Yu Liu, Lingli Huang, Yulian Wang, Bo Yang, Awais Ishan, Ke Fang, Dapeng Peng, Zhenli Liu, Menghong Dai, Zonghui Yuan. Tissue depletion and concentration correlations between edible tissues and biological fluids of 3-amino-2-oxazolidinone in pigs fed with a furazolidone-medicated feed.
Journal of agricultural and food chemistry.
2010 Jun; 58(11):6774-9. doi:
10.1021/jf904577f. [PMID: 20443624] - Yu Liu, Dapeng Peng, Lingli Huang, Yulian Wang, Chao Chang, Awais Ihsan, Yanfei Tao, Bo Yang, Zonghui Yuan. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals.
Analytica chimica acta.
2010 Apr; 664(2):151-7. doi:
10.1016/j.aca.2010.02.010. [PMID: 20363397] - Xiao-Zhong Hu, Ying Xu, Ayfer Yediler. Determinations of residual furazolidone and its metabolite, 3-amino-2-oxazolidinone (AOZ), in fish feeds by HPLC-UV and LC-MS/MS, respectively.
Journal of agricultural and food chemistry.
2007 Feb; 55(4):1144-9. doi:
10.1021/jf062902a. [PMID: 17300147] - K M Cooper, P P J Mulder, J A van Rhijn, L Kovacsics, R J McCracken, P B Young, D G Kennedy. Depletion of four nitrofuran antibiotics and their tissue-bound metabolites in porcine tissues and determination using LC-MS/MS and HPLC-UV.
Food additives and contaminants.
2005 May; 22(5):406-14. doi:
10.1080/02652030512331385218. [PMID: 16019811] - A Auro, H Sumano, L Ocampo, A Barragán. Evaluation of the carcinogenic effects of furazolidone and its metabolites in two fish species.
The pharmacogenomics journal.
2004; 4(1):24-8. doi:
10.1038/sj.tpj.6500216. [PMID: 14647403] - A M Timperio, H A Kuiper, L Zolla. Identification of a furazolidone metabolite responsible for the inhibition of amino oxidases.
Xenobiotica; the fate of foreign compounds in biological systems.
2003 Feb; 33(2):153-67. doi:
10.1080/0049825021000038459. [PMID: 12623758] - R J McCracken, M A McCoy, D G Kennedy. The prevalence and possible causes of bound and extractable residues of the furazolidone metabolite 3-amino-2-oxazolidinone in porcine tissues.
Food additives and contaminants.
1997 Apr; 14(3):287-94. doi:
10.1080/02652039709374526. [PMID: 9135726] - L A Hoogenboom, M C Berghmans, T H Polman, R Parker, I C Shaw. Depletion of protein-bound furazolidone metabolites containing the 3-amino-2-oxazolidinone side-chain from liver, kidney and muscle tissues from pigs.
Food additives and contaminants.
1992 Nov; 9(6):623-30. doi:
10.1080/02652039209374117. [PMID: 1302201]