Fenoterol (BioDeep_00000018306)

   

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


1-(p-Hydroxyphenyl)-2-((beta-hydroxy-beta-(3,5-dihydroxyphenyl))ethyl)aminopropane

化学式: C17H21NO4 (303.1471)
中文名称: 非诺特罗
谱图信息: 最多检出来源 Homo sapiens(blood) 4.97%

分子结构信息

SMILES: CC(CC1=CC=C(C=C1)O)NCC(C2=CC(=CC(=C2)O)O)O
InChI: InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3

描述信息

Fenoterol is only found in individuals that have used or taken this drug. It is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic. [PubChem]Beta(2)-receptor stimulation by fenoterol in the lung causes relaxation of bronchial smooth muscle, bronchodilation, and increased bronchial airflow.
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03C - Adrenergics for systemic use > R03CC - Selective beta-2-adrenoreceptor agonists
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03A - Adrenergics, inhalants > R03AC - Selective beta-2-adrenoreceptor agonists
G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02C - Other gynecologicals > G02CA - Sympathomimetics, labour repressants
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D012102 - Reproductive Control Agents > D015149 - Tocolytic Agents
Fenoterol (Th-1165), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research[1][2].

同义名列表

23 个代谢物同义名

1-(p-Hydroxyphenyl)-2-((beta-hydroxy-beta-(3,5-dihydroxyphenyl))ethyl)aminopropane; 3,5-Dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)benzyl alcohol; 5-{1-hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol; 1-(p-Hydroxyphenyl)-2-((b-hydroxy-b-(3,5-dihydroxyphenyl))ethyl)aminopropane; 1-(p-Hydroxyphenyl)-2-((β-hydroxy-β-(3,5-dihydroxyphenyl))ethyl)aminopropane; 5-(1-hydroxy-2-{[1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,3-diol; 1-(3,5-Dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane; 3,5-Dihydroxy-a-(((p-hydroxy-a-methylphenethyl)amino)methyl)benzyl alcohol; 3,5-Dihydroxy-α-(((p-hydroxy-α-methylphenethyl)amino)methyl)benzyl alcohol; P Hydroxyphenyl orciprenaline; P-Hydroxyphenyl-orciprenaline; P Hydroxyphenylorciprenaline; P-Hydroxyphenylorciprenaline; Hydrochloride, fenoterol; Fenoterol hydrochloride; Fenoterol hydrobromide; Partusisten; Fenoterolum; Phenoterol; fenoterol; Berotek; Berotec; Th-1165



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Marleen J Meyer, Pascale C F Schreier, Mert Basaran, Stefaniia Vlasova, Tina Seitz, Jürgen Brockmöller, Barbara Zdrazil, Mladen V Tzvetkov. Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1. The Journal of biological chemistry. 2022 06; 298(6):101974. doi: 10.1016/j.jbc.2022.101974. [PMID: 35469921]
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  • Ahmad Alzamami, Norah A Alturki, Youssef Saeed Alghamdi, Shaban Ahmad, Saleh Alshamrani, Saeed A Asiri, Mutaib M Mashraqi. Hemi-Babim and Fenoterol as Potential Inhibitors of MPro and Papain-like Protease against SARS-CoV-2: An In-Silico Study. Medicina (Kaunas, Lithuania). 2022 Apr; 58(4):. doi: 10.3390/medicina58040515. [PMID: 35454354]
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  • Mahmoud A Omar, Mohamed A Hammad, Mohamed Awad. Utility of Europium ion characteristic peak for quantitation of Fenoterol hydrobromide and Salmeterol xinafoate in different matrices; application to stability studies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2019 Jun; 217(?):182-189. doi: 10.1016/j.saa.2019.03.072. [PMID: 30933783]
  • Mahmoud A Omar, Mohamed A Hammad, Mohamed Awad. New enhanced spectrofluorimetric approach for picogram detection of Fenoterol hydrobromide through Von Pechman synthesis of coumarins. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2018 Nov; 204(?):702-707. doi: 10.1016/j.saa.2018.06.108. [PMID: 29982162]
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