Fenbendazole (BioDeep_00000018304)
Secondary id: BioDeep_00000014949
human metabolite Endogenous Chemicals and Drugs
代谢物信息卡片
化学式: C15H13N3O2S (299.07284380000004)
中文名称: 芬苯达唑
谱图信息:
最多检出来源 Homo sapiens(blood) 18.15%
分子结构信息
SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)SC3=CC=CC=C3
InChI: InChI=1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)
描述信息
Veterinary anthelmintic. Fenbendazole is a fda approved for use in cattle, pigs and goats Fenbendazole (Hoechst brand names Panacur and Safe-Guard, Intervet Panacur and Panacur Rabbit) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including roundworms, hookworms, whipworms, the taenia species of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles and strongyloides and can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits and seals. Drug interactions may occur if using bromsalan flukicides (Dibromsalan, Tribromsalan). Abortions in cattle and death in sheep have been reported after using these medications together. (Plumbs Veterinary Drug Handbook, Fifth Edition. 2005
P - Antiparasitic products, insecticides and repellents > P02 - Anthelmintics > P02C - Antinematodal agents > P02CA - Benzimidazole derivatives
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1].
同义名列表
26 个代谢物同义名
[5-(Phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester; methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate; [5-(Phenylthio)-1H-benzimidazol-2-yl]carbamate methyl ester; 2-Benzimidazolecarbamic acid, 5-(phenylthio)-, methyl ester; Methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid; Methyl [5-(phenylsulfanyl)-1H-benzimidazol-2-yl]carbamate; 5-(Phenylthio)-2-benzimidazolecarbamic acid methyl ester; Methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate; Methyl (5-(phenylthio)-1H-benzimidazol-2-yl)carbamate; 5-(Phenylthio)-2-benzimidazolecarbamate methyl ester; 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole; Methyl 5-(phenylthio)-2-benzimidazolecarbamic acid; Methyl 5-phenylthio-1H-benzimidazol-2-ylcarbamate; Methyl 5-(phenylthio)-2-benzimidazolecarbamate; Fenbendazolum; Phenbendasol; fenbendazole; Fenbendazol; Worm-a-rest; Safe-quard; Safe-guard; Pancacur; Hoe 881V; Panacur; Hoe 881; Axilur
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:77092
- KEGG: C21876
- PubChem: 3334
- HMDB: HMDB0029745
- DrugBank: DB11410
- ChEMBL: CHEMBL37161
- Wikipedia: Fenbendazole
- MeSH: Fenbendazole
- foodb: FDB000946
- chemspider: 3217
- CAS: 43210-67-9
- PMhub: MS000005620
- medchemexpress: HY-B0413
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Severina Semkova, Biliana Nikolova, Iana Tsoneva, Georgi Antov, Donika Ivanova, Anton Angelov, Zhivko Zhelev, Rumiana Bakalova. Redox-mediated Anticancer Activity of Anti-parasitic Drug Fenbendazole in Triple-negative Breast Cancer Cells.
Anticancer research.
2023 Mar; 43(3):1207-1212. doi:
10.21873/anticanres.16267
. [PMID: 36854536] - M Mauger, G Kelly, C H Annandale, I D Robertson, F K Waichigo, J W Aleri. Anthelmintic resistance of gastrointestinal nematodes in dairy calves within a pasture-based production system of south West Western Australia.
Australian veterinary journal.
2022 Jul; 100(7):283-291. doi:
10.1111/avj.13162
. [PMID: 35383394] - Felipe Romano, José Guilherme Xavier, Ronalda Silva DE Araújo, Selene Dall'Acqua Coutinho, Maria Anete Lallo. Successful use of albendazole and fenbendazole therapy in a cat with persistent diarrhea due Enterocytozoon bieneusi.
The Journal of veterinary medical science.
2022 Jun; 84(6):869-871. doi:
10.1292/jvms.22-0045
. [PMID: 35491092] - Teka Feyera, Anwar Shifaw, Brendan Sharpe, Timothy Elliott, Isabelle Ruhnke, Stephen W Walkden-Brown. Worm control practices on free-range egg farms in Australia and anthelmintic efficacy against nematodes in naturally infected layer chickens.
Veterinary parasitology, regional studies and reports.
2022 05; 30(?):100723. doi:
10.1016/j.vprsr.2022.100723
. [PMID: 35431079] - Julia Carter, Jennifer K Ketzis. Case report: Assessment of a quarantine treatment for sheep on the Caribbean Island of St. Kitts.
Veterinary parasitology, regional studies and reports.
2022 01; 27(?):100660. doi:
10.1016/j.vprsr.2021.100660
. [PMID: 35012717] - Laura B A Williams. Generalized cutaneous urticaria associated with Giardia infection in a five-month old puppy.
Veterinary parasitology, regional studies and reports.
2021 12; 26(?):100643. doi:
10.1016/j.vprsr.2021.100643
. [PMID: 34879954] - S Lagos, C Perruchon, A Tsikriki, E Gourombinos, S Vasileiadis, S Sotiraki, D G Karpouzas. Bioaugmentation of animal feces as a mean to mitigate environmental contamination with anthelmintic benzimidazoles.
Journal of hazardous materials.
2021 10; 419(?):126439. doi:
10.1016/j.jhazmat.2021.126439
. [PMID: 34174622] - Teka Feyera, Isabelle Ruhnke, Brendan Sharpe, Tim Elliott, Anwar Shifaw, Stephen W Walkden-Brown. Comparative therapeutic efficacies of oral and in-water administered levamisole, piperazine and fenbendazole against experimental Ascaridia galli infection in chickens.
Veterinary parasitology.
2021 Oct; 298(?):109514. doi:
10.1016/j.vetpar.2021.109514
. [PMID: 34271320] - Anastasiya I Varlamova, Pavel P Kotchetkov, Ivan A Arkhipov, Salavat S Khalikov, Michael V Arisov, Vladislav E Abramov. Pharmacokinetic profile, tissue residue depletion and anthelmintic efficacy of supramolecular fenbendazole.
International journal of pharmaceutics.
2021 Sep; 607(?):120957. doi:
10.1016/j.ijpharm.2021.120957
. [PMID: 34332062] - Martin K Nielsen, Erica K Gee, Alyse Hansen, Tania Waghorn, Julie Bell, Dave M Leathwick. Monitoring equine ascarid and cyathostomin parasites: Evaluating health parameters under different treatment regimens.
Equine veterinary journal.
2021 Sep; 53(5):902-910. doi:
10.1111/evj.13374
. [PMID: 33119179] - Kamara Rhynd, Daniel P Walsh, Linnell Cm Arthur-Banfield. Efficacy of Fenbendazole and Ivermectin against Trichuris spp. in African Green Monkeys (Chlorocebus sabaeus) in Barbados West Indies.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2021 07; 60(4):475-483. doi:
10.30802/aalas-jaalas-20-000103
. [PMID: 33972010] - Radka Podlipná, Martina Navrátilová, Lucie Raisová Stuchlíková, Kateřina Moťková, Lenka Langhansová, Lenka Skálová, Barbora Szotáková. Soybean (Glycine max) Is Able to Absorb, Metabolize and Accumulate Fenbendazole in All Organs Including Beans.
International journal of molecular sciences.
2021 Jun; 22(13):. doi:
10.3390/ijms22136647
. [PMID: 34206260] - Harry Cridge, Henrique Lupiano, Julia D Nipper, Andrew J Mackin, Jörg M Steiner. Efficacy of a low-dose praziquantel and fenbendazole protocol in the treatment of asymptomatic schistosomiasis in dogs.
Journal of veterinary internal medicine.
2021 May; 35(3):1368-1375. doi:
10.1111/jvim.16142
. [PMID: 33955589] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040
. [PMID: 33910017] - Damian C Lettoof, Fabien Aubret, Francis Spilsbury, Philip W Bateman, James Haberfield, Jordan Vos, Monique Marthe Gagnon. PLASMA BIOCHEMISTRY PROFILES OF WILD WESTERN TIGER SNAKES (NOTECHIS SCUTATUS OCCIDENTALIS) BEFORE AND AFTER SIX MONTHS OF CAPTIVITY.
Journal of wildlife diseases.
2021 04; 57(2):253-263. doi:
10.7589/jwd-d-20-00115
. [PMID: 33822160] - Livio Galosi, Anna Rita Attili, Stefania Perrucci, Francesco C Origgi, Adolfo Maria Tambella, Giacomo Rossi, Vincenzo Cuteri, Maira Napoleoni, Nicholas Aconiti Mandolini, Gianni Perugini, Victor J T Loehr. Health assessment of wild speckled dwarf tortoises, CHERSOBIUS SIGNATUS.
BMC veterinary research.
2021 Mar; 17(1):102. doi:
10.1186/s12917-021-02800-5
. [PMID: 33663511] - Benedetto Morandi, Maria Chiara Sabetti, Fabrizia Veronesi, Giulia Morganti, Marco Pietra, Giovanni Poglayen, Nikolina Linta, Gary Conboy, Roberta Galuppi. A case of a dog refractory to different treatments for pulmonary capillariasis.
Parasitology research.
2021 Mar; 120(3):1137-1141. doi:
10.1007/s00436-020-06940-9
. [PMID: 33103217] - Atefe Saemi Soudkolaei, Gholam Ali Kalidari, Hassan Borji. Anthelmintic efficacy of fenbendazole and levamisole in native fowl in northern Iran.
Parasites & vectors.
2021 Feb; 14(1):104. doi:
10.1186/s13071-021-04605-9
. [PMID: 33557928] - Vanessa O Ezenwa, Sarah A Budischak, Peter Buss, Mauricio Seguel, Gordon Luikart, Anna E Jolles, Kaori Sakamoto. Natural resistance to worms exacerbates bovine tuberculosis severity independently of worm coinfection.
Proceedings of the National Academy of Sciences of the United States of America.
2021 01; 118(3):. doi:
10.1073/pnas.2015080118
. [PMID: 33431676] - Dave J Bartley, Natalie J Jewell, Leigh M Andrews, Sian Mitchell, Alison A Morrison. Molecular and phenotypic characterisation of fenbendazole resistance in a field-derived isolate of Ostertagia ostertagi.
Veterinary parasitology.
2021 Jan; 289(?):109319. doi:
10.1016/j.vetpar.2020.109319
. [PMID: 33249304] - Hee Ji Shin, Min Jeong Jo, Ik Sup Jin, Chun-Woong Park, Jin-Seok Kim, Dae Hwan Shin. Optimization and Pharmacokinetic Evaluation of Synergistic Fenbendazole and Rapamycin Co-Encapsulated in Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles.
International journal of nanomedicine.
2021; 16(?):4873-4889. doi:
10.2147/ijn.s315782
. [PMID: 34295160] - Oday T Ali, Wafaa S Hassan, Ahdab N Khayyat, Ahmad J Almalki, Mahmoud M Sebaiy. HPLC Determination of Imidazoles with Variant Anti-Infective Activity in Their Dosage Forms and Human Plasma.
Molecules (Basel, Switzerland).
2020 Dec; 26(1):. doi:
10.3390/molecules26010129
. [PMID: 33396585] - Antonio Bosco, Jan Kießler, Alessandra Amadesi, Marian Varady, Barbara Hinney, Davide Ianniello, Maria Paola Maurelli, Giuseppe Cringoli, Laura Rinaldi. The threat of reduced efficacy of anthelmintics against gastrointestinal nematodes in sheep from an area considered anthelmintic resistance-free.
Parasites & vectors.
2020 Sep; 13(1):457. doi:
10.1186/s13071-020-04329-2
. [PMID: 32907633] - Long Chang, Liqian Zhu. Dewormer drug fenbendazole has antiviral effects on BoHV-1 productive infection in cell cultures.
Journal of veterinary science.
2020 Sep; 21(5):e72. doi:
10.4142/jvs.2020.21.e72
. [PMID: 33016019] - João Henrique Silva Vera, Daniele Floriano Fachiolli, Lívia Magosso Ramires, Isabela de Lima Saes, Paulo Henrique Yamada, Juliana Alencar Gonçalves, Kátia de Oliveira, Alessandro Francisco Talamini do Amarante, Ricardo Velludo Gomes de Soutello. Eficacy of ivermectin, moxidectin and febendazole in equine in Brazil.
Veterinary parasitology, regional studies and reports.
2020 04; 20(?):100374. doi:
10.1016/j.vprsr.2020.100374
. [PMID: 32448518] - Andresa Guimarães, Verônica C O Aguilera, Douglas P P Gomes, Evelyn V Zanesco, Ágatha F X Oliveira, Naiara V Stocco, Gustavo F P Andrade, Nicole C Souza, Heloisa J M Souza, Cristiane D Baldani. Urinary capillariosis in a cat from Rio de Janeiro, Brazil - Clinical, morphological and phylogenetic characterization.
Veterinary parasitology, regional studies and reports.
2020 04; 20(?):100409. doi:
10.1016/j.vprsr.2020.100409
. [PMID: 32448522] - Kaley G Mackie, Paula I Menzies, Ken G Bateman, Jessica L Gordon. Efficacy of fenbendazole and ivermectin in treating gastrointestinal nematode infections in an Ontario cow-calf herd.
The Canadian veterinary journal = La revue veterinaire canadienne.
2019 Nov; 60(11):1213-1219. doi:
NULL
. [PMID: 31692638] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Jennifer L Cain, Donna Foulk, Edward Jedrzejewski, Heather Stofanak, Martin K Nielsen. The importance of anthelmintic efficacy monitoring: results of an outreach effort.
Parasitology research.
2019 Oct; 118(10):2877-2883. doi:
10.1007/s00436-019-06423-6
. [PMID: 31422463] - Prashant Pawar, Lachhman Das Singla, Paramjit Kaur, Mandeep Singh Bal, Mohamad Javed. Evaluation and Correlation of Multiple Anthelmintic Resistances to Gastrointestinal Nematodes Using Different Fecal Egg Count Reduction Methods in Small Ruminants of Punjab, India.
Acta parasitologica.
2019 Sep; 64(3):456-463. doi:
10.2478/s11686-019-00083-3
. [PMID: 31165992] - A K Dixit, G Das, P Dixit, R L Sharma. Efficacy of herbal extracts and closantel against fenbendazole-resistant Haemonchus contortus.
Journal of helminthology.
2019 Sep; 93(5):529-532. doi:
10.1017/s0022149x18000627
. [PMID: 30039771] - Daniel Yasur-Landau, Alicia Rojas, Tamar Zehavi, Yuval Yafe, Yigal Anug, Gad Baneth. First molecular identification of Aelurostrongylus abstrusus in a cat presenting severe respiratory disease from Israel.
Veterinary parasitology, regional studies and reports.
2019 08; 17(?):100304. doi:
10.1016/j.vprsr.2019.100304
. [PMID: 31303224] - Luise Kultscher, Barbara Hinney, Ronald Schmäschke, Anja Joachim, Thomas Wittek. Current anthelmintic treatment is not always effective at controlling strongylid infections in German alpaca herds.
Parasites & vectors.
2019 Jul; 12(1):330. doi:
10.1186/s13071-019-3588-3
. [PMID: 31266521] - Laura Ceballos, Candela Canton, Gabriela Cadenazzi, Guillermo Virkel, Paula Dominguez, Laura Moreno, Carlos Lanusse, Luis Alvarez. Oxfendazole kinetics in pigs: In vivo assessment of its pattern of accumulation in Ascaris suum.
Experimental parasitology.
2019 Apr; 199(?):52-58. doi:
10.1016/j.exppara.2019.02.017
. [PMID: 30831078] - Eliška Syslová, Přemysl Landa, Lucie Raisová Stuchlíková, Petra Matoušková, Lenka Skálová, Barbora Szotáková, Martina Navrátilová, Tomáš Vaněk, Radka Podlipná. Metabolism of the anthelmintic drug fenbendazole in Arabidopsis thaliana and its effect on transcriptome and proteome.
Chemosphere.
2019 Mar; 218(?):662-669. doi:
10.1016/j.chemosphere.2018.11.135
. [PMID: 30502705] - Wojciech Karlik, Magdalena Chłopecka, Magdalena Bamburowicz-Klimkowska, Marta Mendel. Modulations of bovine hepatic microsomal metabolism of benzimidazoles by secondary plant metabolites.
Journal of veterinary pharmacology and therapeutics.
2019 Mar; 42(2):222-229. doi:
10.1111/jvp.12727
. [PMID: 30474118] - Saad S Enouri, Michele T Guerin, Innes G Wilson, Patricia M Dowling, Ron J Johnson. Tissue residue depletion of fenbendazole after oral administration in turkeys.
The Canadian veterinary journal = La revue veterinaire canadienne.
2019 03; 60(3):282-286. doi:
NULL
. [PMID: 30872851] - Aman Dev Moudgil, Lachhman Das Singla. Molecular confirmation and anthelmintic efficacy assessment against natural trichurid infections in zoo-housed non-human primates.
Journal of medical primatology.
2018 12; 47(6):388-392. doi:
10.1111/jmp.12358
. [PMID: 29979810] - Fengping He, Jiancheng Zhai, Le Zhang, Dan Liu, Yue Ma, Ke Rong, Yanchun Xu, Jianzhang Ma. Variations in gut microbiota and fecal metabolic phenotype associated with Fenbendazole and Ivermectin Tablets by 16S rRNA gene sequencing and LC/MS-based metabolomics in Amur tiger.
Biochemical and biophysical research communications.
2018 05; 499(3):447-453. doi:
10.1016/j.bbrc.2018.03.158
. [PMID: 29596832] - Scott W Korte, Craig L Franklin, Rebecca A Dorfmeyer, Aaron C Ericsson. Effects of Fenbendazole-impregnated Feed and Topical Moxidectin during Quarantine on the Gut Microbiota of C57BL/6 Mice.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2018 05; 57(3):229-235. doi:
NULL
. [PMID: 29784074] - Cunchun Dai, Shaoqi Qu, Ruili Zhang, Li Zhao, Yuwen Li, Jiajia Zhu, Chunmei Wang, Hui Guo, Zhihui Hao. Development and analytical characterization of a new antiparasitic fenbendazole compound tablet and pharmacokinetic investigations after its oral administration to dogs.
Die Pharmazie.
2018 Feb; 73(2):70-75. doi:
10.1691/ph.2018.7123
. [PMID: 29442007] - Pramod N Nehete, Gregory Wilkerson, Bharti P Nehete, Sriram Chitta, Julio C Ruiz, Henrieta Scholtzova, Lawrence E Williams, Christian R Abee, John A Vanchiere. Cellular immune responses in peripheral blood lymphocytes of Giardia infected squirrel monkey (Saimiri boliviensis boliviensis) treated with Fenbendazole.
PloS one.
2018; 13(11):e0198497. doi:
10.1371/journal.pone.0198497
. [PMID: 30412580] - Sajid Umar, Seema Abbas, Muhammad Irfan Khan, Qamarun Nisa, Muhammad Younus, Kiran Aqil, Rizwan Qayyum, Muhammad Yaqoob, Asif Ali, Muhammad Asif Yaseen, Muhammad Ali Shah. Safety of fenbendazole in common peafowl (Pavo cristatus).
Pakistan journal of pharmaceutical sciences.
2018 Jan; 31(1):159-167. doi:
NULL
. [PMID: 29348098] - Anna M Pyziel, Sven Björck, Rikard Wiklund, Moa Skarin, Aleksander W Demiaszkiewicz, Johan Höglund. Gastrointestinal parasites of captive European bison Bison bonasus (L.) with a sign of reduced efficacy of Haemonchus contortus to fenbendazole.
Parasitology research.
2018 Jan; 117(1):295-302. doi:
10.1007/s00436-017-5663-z
. [PMID: 29090320] - Lucie Raisová Stuchlíková, Lenka Skálová, Barbora Szotáková, Eliška Syslová, Ivan Vokřál, Tomáš Vaněk, Radka Podlipná. Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata).
Ecotoxicology and environmental safety.
2018 Jan; 147(?):681-687. doi:
10.1016/j.ecoenv.2017.09.020
. [PMID: 28934712] - G Sallé, J Cortet, I Bois, C Dubès, Q Guyot-Sionest, C Larrieu, V Landrin, G Majorel, S Wittreck, E Woringer, A Couroucé, J Guillot, P Jacquiet, F Guégnard, A Blanchard, A Leblond. Risk factor analysis of equine strongyle resistance to anthelmintics.
International journal for parasitology. Drugs and drug resistance.
2017 12; 7(3):407-415. doi:
10.1016/j.ijpddr.2017.10.007
. [PMID: 29149701] - Abdullah D Alanazi, Rami M Mukbel, Mohamed S Alyousif, Zafer S AlShehri, Ibrahim O Alanazi, Hamdan I Al-Mohammed. A field study on the anthelmintic resistance of Parascaris spp. in Arab foals in the Riyadh region, Saudi Arabia.
The veterinary quarterly.
2017 Dec; 37(1):200-205. doi:
10.1080/01652176.2017.1334981
. [PMID: 28537782] - Paola Paradies, Fabrizio Iarussi, Mariateresa Sasanelli, Antonio Capogna, Riccardo Paolo Lia, Daniele Zucca, Beatrice Greco, Cinzia Cantacessi, Domenico Otranto. Occurrence of strongyloidiasis in privately owned and sheltered dogs: clinical presentation and treatment outcome.
Parasites & vectors.
2017 Jul; 10(1):345. doi:
10.1186/s13071-017-2275-5
. [PMID: 28728589] - Pratibha Kapoor, Yumiko O Hayes, Leslie T Jarrell, Dwight A Bellinger, Rhiannon D Thomas, Gregory W Lawson, Jaclyn D Arkema, Craig A Fletcher, Judith N Nielsen. Evaluation of Anthelmintic Resistance and Exhaust Air Dust PCR as a Diagnostic Tool in Mice Enzootically Infected with Aspiculuris tetraptera.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2017 May; 56(3):273-289. doi:
NULL
. [PMID: 28535863] - Brian Lassen, Claudio Oliviero, Toomas Orro, Elias Jukola, Tapio Laurila, Minna Haimi-Hakala, Mari Heinonen. Effect of fenbendazole in water on pigs infected with Ascaris suum in finishing pigs under field conditions.
Veterinary parasitology.
2017 Apr; 237(?):1-7. doi:
10.1016/j.vetpar.2017.03.005
. [PMID: 28285891] - Nadine Ravinet, Anne Lehebel, Nathalie Bareille, Carlos Lopez, Christophe Chartier, Alain Chauvin, Aurélien Madouasse. Design and evaluation of multi-indicator profiles for targeted-selective treatment against gastrointestinal nematodes at housing in adult dairy cows.
Veterinary parasitology.
2017 Apr; 237(?):17-29. doi:
10.1016/j.vetpar.2017.03.001
. [PMID: 28274492] - T Yu Degtyarevskaya, T V Sakharova, S N Larina, N V Chebyshev. [(IMPACT OF LUNGWORM INFESTATION ON THE BIOCHEMICAL PARAMETERS OF ANIMALS DURING COMBINATION TREATMENT WITH ALBENDAZOLE AND T- AND B-ACTIVIN)].
Meditsinskaia parazitologiia i parazitarnye bolezni.
2017 Apr; ?(2):46-48. doi:
. [PMID: 30721604]
- Renata Coltro Bezagio, Cristiane Maria Colli, Liara Izabela Lopes Romera, Érika Cristina Ferreira, Ana Lúcia Falavigna-Guilherme, Mônica Lúcia Gomes. Synergistic effects of fenbendazole and metronidazole against Giardia muris in Swiss mice naturally infected.
Parasitology research.
2017 Mar; 116(3):939-944. doi:
10.1007/s00436-016-5367-9
. [PMID: 28039497] - M Milhes, M Guillerm, M Robin, M Eichstadt, C Roy, C Grisez, F Prévot, E Liénard, E Bouhsira, M Franc, P Jacquiet. A real-time PCR approach to identify anthelmintic-resistant nematodes in sheep farms.
Parasitology research.
2017 Mar; 116(3):909-920. doi:
10.1007/s00436-016-5364-z
. [PMID: 28101647] - Mason V Reichard, Jennifer E Thomas, Maria Chavez-Suarez, Cassandra O Cullin, Gary L White, Emily C Wydysh, Roman F Wolf. Pilot Study to Assess the Efficacy of Ivermectin and Fenbendazole for Treating Captive-Born Olive Baboons (Papio anubis) Coinfected with Strongyloides fülleborni and Trichuris trichiura.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2017 Jan; 56(1):52-56. doi:
NULL
. [PMID: 28905715] - M K Vijayasarathi, C Sreekumar, R Venkataramanan, M Raman. Influence of sustained deworming pressure on the anthelmintic resistance status in strongyles of sheep under field conditions.
Tropical animal health and production.
2016 Oct; 48(7):1455-62. doi:
10.1007/s11250-016-1117-3
. [PMID: 27509876] - T Westers, A Jones-Bitton, P Menzies, J Van Leeuwen, Z Poljak, A S Peregrine. Efficacy of closantel against ivermectin- and fenbendazole-resistant Haemonchus sp. in sheep in Ontario, Canada.
Veterinary parasitology.
2016 Sep; 228(?):30-41. doi:
10.1016/j.vetpar.2016.08.009
. [PMID: 27692328] - Meriam N Saleh, Alexandra D Gilley, Meghan K Byrnes, Anne M Zajac. Development and evaluation of a protocol for control of Giardia duodenalis in a colony of group-housed dogs at a veterinary medical college.
Journal of the American Veterinary Medical Association.
2016 Sep; 249(6):644-9. doi:
10.2460/javma.249.6.644
. [PMID: 27585102] - S P Daniels, C J Proudman. Ovicidal efficacy of fenbendazole after treatment of horses naturally infected with cyathostomins.
Veterinary parasitology.
2016 Aug; 227(?):151-6. doi:
10.1016/j.vetpar.2016.08.004
. [PMID: 27523952] - Hélio L Barros, Sandra M T Marques, Valter Stefani. The use of epifluorescence microscopy and fluorescent dyes for visualization of Oxyuris equi eggs.
Veterinary parasitology.
2016 Aug; 226(?):162-6. doi:
10.1016/j.vetpar.2016.06.039
. [PMID: 27514902] - Kristoffer Relling Tysnes, Katrien Luyckx, Leon Cantas, Lucy J Robertson. Treatment of feline giardiasis during an outbreak of diarrhoea in a cattery: potential effects on faecal Escherichia coli resistance patterns.
Journal of feline medicine and surgery.
2016 08; 18(8):679-82. doi:
10.1177/1098612x15588798
. [PMID: 26071424] - Lucie Stuchlíková, Robert Jirásko, Lenka Skálová, František Pavlík, Barbora Szotáková, Michal Holčapek, Tomáš Vaněk, Radka Podlipná. Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia).
Chemosphere.
2016 Aug; 157(?):10-7. doi:
10.1016/j.chemosphere.2016.05.015
. [PMID: 27208642] - Dana M Lindemann, David Eshar, Jerome C Nietfeld, In Joong Kim. SUSPECTED FENBENDAZOLE TOXICITY IN AN AMERICAN WHITE PELICAN (PELECANUS ERYTHRORHYNCHOS).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2016 Jun; 47(2):681-5. doi:
10.1638/2015-0117.1
. [PMID: 27468051] - Fernanda Ramos, Luiza Pires Portella, Fernando de Souza Rodrigues, Caroline Zamperete Reginato, Luciana Pötter, Alfredo Skrebsky Cezar, Luís Antônio Sangioni, Fernanda Silveira Flores Vogel. Anthelmintic resistance in gastrointestinal nematodes of beef cattle in the state of Rio Grande do Sul, Brazil.
International journal for parasitology. Drugs and drug resistance.
2016 Apr; 6(1):93-101. doi:
10.1016/j.ijpddr.2016.02.002
. [PMID: 27054068] - Jessica Y Rodriguez, Joseph W Camp, Stephen D Lenz, Kevin R Kazacos, Karen F Snowden. Identification of Heterobilharzia americana infection in a dog residing in Indiana with no history of travel.
Journal of the American Veterinary Medical Association.
2016 Apr; 248(7):827-30. doi:
10.2460/javma.248.7.827
. [PMID: 27003025] - Nadine Ravinet, Christophe Chartier, Nathalie Bareille, Anne Lehebel, Adeline Ponnau, Nadine Brisseau, Alain Chauvin. Unexpected Decrease in Milk Production after Fenbendazole Treatment of Dairy Cows during Early Grazing Season.
PloS one.
2016; 11(1):e0147835. doi:
10.1371/journal.pone.0147835
. [PMID: 26808824] - M K Nielsen, A T Loynachan, S Jacobsen, J C Stewart, C R Reinemeyer, D W Horohov. Local and systemic inflammatory and immunologic reactions to cyathostomin larvicidal therapy in horses.
Veterinary immunology and immunopathology.
2015 Dec; 168(3-4):203-10. doi:
10.1016/j.vetimm.2015.09.009
. [PMID: 26429413] - Gabriella Klausz, Éva Keller, Zoltán Sára, Péter Székely-Körmöczy, Péter Laczay, Kornélia Ary, Péter Sótonyi, Kálmán Róna. Simultaneous determination of praziquantel, pyrantel embonate, febantel and its active metabolites, oxfendazole and fenbendazole, in dog plasma by liquid chromatography/mass spectrometry.
Biomedical chromatography : BMC.
2015 Dec; 29(12):1859-65. doi:
10.1002/bmc.3507
. [PMID: 26104502] - Simon Cook, Simon L Priestnall, Damer Blake, Richard L Meeson. Angiostrongylus vasorum Causing Severe Granulomatous Hepatitis with Concurrent Multiple Acquired PSS.
Journal of the American Animal Hospital Association.
2015 Sep; 51(5):320-4. doi:
10.5326/jaaha-ms-6210
. [PMID: 26355583] - Maria B Studzińska, Justyna Obara-Gałek, Marta Demkowska-Kutrzepa, Krzysztof Tomczuk. Diagnosis and therapy of Capillaria plica infection: report and literature review.
Acta parasitologica.
2015 Sep; 60(3):563-6. doi:
10.1515/ap-2015-0081
. [PMID: 26204197] - Robert W Li, Sitao Wu, Cong-Jun Li, Weizhong Li, Steven G Schroeder. Splice variants and regulatory networks associated with host resistance to the intestinal worm Cooperia oncophora in cattle.
Veterinary parasitology.
2015 Jul; 211(3-4):241-50. doi:
10.1016/j.vetpar.2015.05.010
. [PMID: 26025321] - Dawn M Roellig, Johanna S Salzer, Darin S Carroll, Jana M Ritter, Clifton Drew, Nadia Gallardo-Romero, M Shannon Keckler, Gregory Langham, Christina L Hutson, Kevin L Karem, Thomas R Gillespie, Govinda S Visvesvara, Maureen G Metcalfe, Inger K Damon, Lihua Xiao. Identification of Giardia duodenalis and Enterocytozoon bieneusi in an epizoological investigation of a laboratory colony of prairie dogs, Cynomys ludovicianus.
Veterinary parasitology.
2015 May; 210(1-2):91-7. doi:
10.1016/j.vetpar.2015.03.022
. [PMID: 25881801] - L C Falzon, J van Leeuwen, P I Menzies, A Jones-Bitton, W Sears, J T Jansen, A S Peregrine. Comparison of calculation methods used for the determination of anthelmintic resistance in sheep in a temperate continental climate.
Parasitology research.
2015 Apr; 114(4):1631-43. doi:
10.1007/s00436-014-4253-6
. [PMID: 25681141] - L R Mozzer, W S Lima. Gallus gallus domesticus: paratenic host of Angiostrongylus vasorum.
Veterinary parasitology.
2015 Jan; 207(1-2):81-4. doi:
10.1016/j.vetpar.2014.11.003
. [PMID: 25468671] - Zdenka Soukupova-Markova, Veronika Doubkova, Petr Marsalek, Zdenka Svobodova, Ivana Papezikova, Stepan Lang, Stanislav Navratil, Miroslava Palikova. Degradation rate of praziquantel and fenbendazole in rainbow trout following oral administration.
Neuro endocrinology letters.
2015; 36 Suppl 1(?):64-7. doi:
. [PMID: 26757113]
- J T Howard, R E Baynes, J D Brooks, J L Yeatts, B Bellis, M S Ashwell, P Routh, A T O'Nan, C Maltecca. The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine.
Journal of veterinary pharmacology and therapeutics.
2014 Dec; 37(6):531-41. doi:
10.1111/jvp.12128
. [PMID: 24731191] - Eugene T Lyons, Sharon C Tolliver, Tetiana A Kuzmina, Igor I Dzeverin, Martin K Nielsen, Karen J McDowell. Profiles of strongyle EPG values for Thoroughbred mares on 14 farms in Kentucky (2012-2013).
Veterinary parasitology.
2014 Oct; 205(3-4):646-52. doi:
10.1016/j.vetpar.2014.08.001
. [PMID: 25195192] - Maren E Mason, Nathan D Voris, Hunter A Ortis, Amy A Geeding, Ray M Kaplan. Comparison of a single dose of moxidectin and a five-day course of fenbendazole to reduce and suppress cyathostomin fecal egg counts in a herd of embryo transfer-recipient mares.
Journal of the American Veterinary Medical Association.
2014 Oct; 245(8):944-51. doi:
10.2460/javma.245.8.944
. [PMID: 25285937] - S K Armstrong, R G Woodgate, S Gough, J Heller, N C Sangster, K J Hughes. The efficacy of ivermectin, pyrantel and fenbendazole against Parascaris equorum infection in foals on farms in Australia.
Veterinary parasitology.
2014 Oct; 205(3-4):575-80. doi:
10.1016/j.vetpar.2014.08.028
. [PMID: 25224788] - Talia Gattenuo, Jennifer Ketzis, Linda Shell. Fenbendazole treatment for Mammomonogamus species infection of a domestic cat on St Kitts, West Indies.
Journal of feline medicine and surgery.
2014 Oct; 16(10):864-6. doi:
10.1177/1098612x14529297
. [PMID: 24710593] - Chia-Wen Hsu, Jinghua Zhao, Ruili Huang, Jui-Hua Hsieh, Jon Hamm, Xiaoqing Chang, Keith Houck, Menghang Xia. Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.
Scientific reports.
2014 Sep; 4(?):6437. doi:
10.1038/srep06437
. [PMID: 25257666] - Andrew S Peregrine, Stephanie G Nykamp, Heather Carey, Stephen Kruth. Paragonimosis in a cat and the temporal progression of pulmonary radiographic lesions following treatment.
Journal of the American Animal Hospital Association.
2014 Sep; 50(5):356-60. doi:
10.5326/jaaha-ms-6053
. [PMID: 25028442] - Catherine M Bianchi, Cassidy B Johnson, Lauren L Howard, Paul Crump. Efficacy of fenbendazole and levamisole treatments in captive Houston toads (Bufo [Anaxyrus] houstonensis).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2014 Sep; 45(3):564-8. doi:
10.1638/2013-0250r.1
. [PMID: 25314823] - R Griffith, M Yaeger, S Hostetter, L A Tell, S Wetzlich, T Vickroy, B Lillie, W MacFarlane, T Laudenslager, E Whitley, R Dzikamunhenga, W Larson. Safety of fenbendazole in Chinese ring-necked pheasants (Phasianus colchicus).
Avian diseases.
2014 Mar; 58(1):8-15. doi:
10.1637/10479-010213-reg.1
. [PMID: 24758107] - Kyung-Yeon Eo, Dongmi Kwak, Oh-Deog Kwon. Severe whipworm (Trichuris spp.) infection in the dromedary (Camelus dromedarius).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2014 Mar; 45(1):190-2. doi:
10.1638/2013-0155r1.1
. [PMID: 24712184] - Susan M Thomas, Eric R Morgan. Effect on performance of weanling alpacas following treatments against gastro-intestinal parasites.
Veterinary parasitology.
2013 Nov; 198(1-2):244-9. doi:
10.1016/j.vetpar.2013.08.010
. [PMID: 24021542] - W De Jaeghere, B G De Geest, J Van Bocxlaer, J P Remon, C Vervaet, A Antunes da Fonseca. Formulation of poorly water-soluble drugs via coacervation--a pilot study using febantel.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2013 Nov; 85(3 Pt B):930-5. doi:
10.1016/j.ejpb.2013.07.006
. [PMID: 23872178] - Ricardo J Canever, Pollyana R C Braga, Albert Boeckh, Marcelly Grycajuck, Daniele Bier, Marcelo B Molento. Lack of Cyathostomin sp. reduction after anthelmintic treatment in horses in Brazil.
Veterinary parasitology.
2013 May; 194(1):35-9. doi:
10.1016/j.vetpar.2012.12.020
. [PMID: 23318166] - J P Dubey, M Prowell. Ante-mortem diagnosis, diarrhea, oocyst shedding, treatment, isolation, and genetic typing of Toxoplasma gondii associated with clinical toxoplasmosis in a naturally infected cat.
The Journal of parasitology.
2013 Feb; 99(1):158-60. doi:
10.1645/ge-3257.1
. [PMID: 22924914] - A C Clark, F R López, J M Levine, J J Cooper, T M Craig, A K Voges, M C Johnson, B F Porter. Intracranial migration of Eucoleus (Capillaria) boehmi in a dog.
The Journal of small animal practice.
2013 Feb; 54(2):99-103. doi:
10.1111/j.1748-5827.2012.01303.x
. [PMID: 23146113] - B D Kruse, K Hartmann, A Groth, B Schulz, A Wehner. [Disseminated intravascular coagulopathy in a dog with Angiostrongylus vasorum infection].
Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere.
2013; 41(6):401-7. doi:
NULL
. [PMID: 24326880] - Marie Mény, Anne Schmidt-Küntzel, Laurie L Marker. Diagnosis-based treatment of helminths in captive and wild cheetahs (Acinonyx jubatus).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2012 Dec; 43(4):934-8. doi:
10.1638/2012-0028r1.1
. [PMID: 23272366] - L Moreno, M T Lopez-Urbina, C Farias, G Domingue, M Donadeu, B Dungu, H H García, L A Gomez-Puerta, C Lanusse, A E González. A high oxfendazole dose to control porcine cysticercosis: pharmacokinetics and tissue residue profiles.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Oct; 50(10):3819-25. doi:
10.1016/j.fct.2012.07.023
. [PMID: 22841955] - Anas Abdelqader, Bassam Qarallah, Diya Al-Ramamneh, Gürbüz Daş. Anthelmintic effects of citrus peels ethanolic extracts against Ascaridia galli.
Veterinary parasitology.
2012 Aug; 188(1-2):78-84. doi:
10.1016/j.vetpar.2012.03.003
. [PMID: 22463876] - Ruth Fiechter, Peter Deplazes, Manuela Schnyder. Control of Giardia infections with ronidazole and intensive hygiene management in a dog kennel.
Veterinary parasitology.
2012 Jun; 187(1-2):93-8. doi:
10.1016/j.vetpar.2011.12.023
. [PMID: 22240238] - King S Nalubamba, Ntombi B Mudenda. Anthelmintic efficacy in captive wild impala antelope (Aepyceros melampus) in Lusaka, Zambia.
Veterinary parasitology.
2012 May; 186(3-4):532-7. doi:
10.1016/j.vetpar.2011.11.020
. [PMID: 22115945] - Julian A Lunn, Rogan Lee, Joanna Smaller, Bruce M MacKay, Terry King, Geraldine B Hunt, Patricia Martin, Mark B Krockenberger, Derek Spielman, Richard Malik. Twenty two cases of canine neural angiostrongylosis in eastern Australia (2002-2005) and a review of the literature.
Parasites & vectors.
2012 04; 5(?):70. doi:
10.1186/1756-3305-5-70
. [PMID: 22480148] - Bert E Stromberg, Louis C Gasbarre, Audie Waite, David T Bechtol, Michael S Brown, Nicholas A Robinson, Erik J Olson, Harold Newcomb. Cooperia punctata: effect on cattle productivity?.
Veterinary parasitology.
2012 Feb; 183(3-4):284-91. doi:
10.1016/j.vetpar.2011.07.030
. [PMID: 21821358] - Carol R Gardner, Vladimir Mishin, Jeffrey D Laskin, Debra L Laskin. Exacerbation of acetaminophen hepatotoxicity by the anthelmentic drug fenbendazole.
Toxicological sciences : an official journal of the Society of Toxicology.
2012 Feb; 125(2):607-12. doi:
10.1093/toxsci/kfr301
. [PMID: 22048645]