Quadazocine (BioDeep_00000182793)
human metabolite blood metabolite
代谢物信息卡片
化学式: C25H37NO2 (383.2824142)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCN(C(C1(C)CCC(=O)CCC3CCCC3)CC4=C2C=C(C=C4)O)C
InChI: InChI=1S/C25H37NO2/c1-24-14-15-26(3)23(16-19-9-11-21(28)17-22(19)24)25(24,2)13-12-20(27)10-8-18-6-4-5-7-18/h9,11,17-18,23,28H,4-8,10,12-16H2,1-3H3
描述信息
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D009292 - Narcotic Antagonists
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- E R Butelman, T J Harris, M J Kreek. Effects of E-2078, a stable dynorphin A(1-8) analog, on sedation and serum prolactin levels in rhesus monkeys.
Psychopharmacology.
1999 Nov; 147(1):73-80. doi:
10.1007/s002130051144. [PMID: 10591871] - E R Butelman, T J Harris, A Perez, M J Kreek. Effects of systemically administered dynorphin A(1-17) in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics.
1999 Aug; 290(2):678-86. doi:
NULL. [PMID: 10411578] - J A Vivian, M B DeYoung, T L Sumpter, J R Traynor, J W Lewis, J H Woods. kappa-Opioid receptor effects of butorphanol in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics.
1999 Jul; 290(1):259-65. doi:
NULL. [PMID: 10381785] - F R Cagampang, K Maeda. Effects of intracerebroventricular administration of opiate receptor antagonists on the suppressed pulsatile LH release during acute fasting in ovariectomized estradiol-treated rats.
Life sciences.
1991; 49(24):1823-8. doi:
10.1016/0024-3205(91)90484-s. [PMID: 1658522] - L A Pohorecky, V A Patel, P Roberts. Effects of ethanol on plasma corticosterone and rectal temperature modification by U50488H and WIN 44441-3.
Life sciences.
1989; 44(22):1637-43. doi:
10.1016/0024-3205(89)90480-3. [PMID: 2543875] - K Yang, N B Haynes, G E Lamming, A N Brooks. Ovarian steroid hormone involvement in endogenous opioid modulation of LH secretion in mature ewes during the breeding and non-breeding seasons.
Journal of reproduction and fertility.
1988 May; 83(1):129-39. doi:
10.1530/jrf.0.0830129. [PMID: 3397932] - L A Dykstra, D E Gmerek, G Winger, J H Woods. Kappa opioids in rhesus monkeys. II. Analysis of the antagonistic actions of quadazocine and beta-funaltrexamine.
The Journal of pharmacology and experimental therapeutics.
1987 Aug; 242(2):421-7. doi:
. [PMID: 3302207] - B A Dodson, K W Miller. Evidence for a dual mechanism in the anesthetic action of an opioid peptide.
Anesthesiology.
1985 May; 62(5):615-20. doi:
10.1097/00000542-198505000-00013. [PMID: 2859816] - R Pechnick, R George, R E Poland. Identification of multiple opiate receptors through neuroendocrine responses. II. Antagonism of mu, kappa and sigma agonists by naloxone and WIN 44,441-3.
The Journal of pharmacology and experimental therapeutics.
1985 Jan; 232(1):170-7. doi:
NULL. [PMID: 2981314] - J P Huidobro-Toro, S Parada. Kappa-opiates and urination: pharmacological evidence for an endogenous role of the kappa-opiate receptor in fluid and electrolyte balance.
European journal of pharmacology.
1984 Dec; 107(1):1-10. doi:
10.1016/0014-2999(84)90084-0. [PMID: 6098480] - M T Curtis, A M Lefer. Beneficial action of a new opiate antagonist (Win 44,441-3) in hemorrhagic shock.
European journal of pharmacology.
1982 Mar; 78(3):307-13. doi:
10.1016/0014-2999(82)90032-2. [PMID: 6279411]