Poly(lactic acid-co-glycolic acid) (BioDeep_00000182528)
human metabolite blood metabolite
代谢物信息卡片
Dimethyldioxanedione polymer with dioxanedione polymer
化学式: C5H8O5 (148.0371718)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 40%
分子结构信息
SMILES: CC(C(=O)O)OC(=O)CO
InChI: InChI=1S/C5H8O5/c1-3(5(8)9)10-4(7)2-6/h3,6H,2H2,1H3,(H,8,9)
描述信息
同义名列表
18 个代谢物同义名
Dimethyldioxanedione polymer with dioxanedione polymer; Dioxanedione polymer with dimethyldioxanedione polymer; 2-[(2-hydroxyacetyl)oxy]propanoic acid; 2-(2-Hydroxyacetyl)oxypropanoic acid; 2-[(2-Hydroxyacetyl)oxy]propanoate; Poly(lactic acid-co-glycolic acid); Poly(glycolide lactide)copolymer; Acid polyester, glycolic-lactic; Polyester, glycolic-lactic acid; Glycolic lactic acid polyester; Glycolic-lactic acid polyester; Poly(lactide-CO-glycolide); Poly(lactate-CO-glycolate); Poly(lactide-CO-glycoside); Polygalactin 910; Polyglactin 910; Polyglactin; Vicryl
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- P E Jai Rexlin, Anju Cecil, Rajalakshmanan Eswaramoorthy, Rubin S John. CHARACTERISATION OF RESORBABLE AND NON- RESORBABLE SUTURES COATED WITH Punica granatum SEED EXTRACT: AN in vitro PILOT STUDY.
The journal of evidence-based dental practice.
2024 Mar; 24(1):101952. doi:
10.1016/j.jebdp.2023.101952. [PMID: 38448126] - Yongzhan Zhu, Yinghao Li, Xiaosong Zhou, Haoxuan Li, Min Guo, Peibiao Zhang. Glucose microenvironment sensitive degradation of arginine modified calcium sulfate reinforced poly(lactide-co-glycolide) composite scaffolds.
Journal of materials chemistry. B.
2024 Jan; 12(2):508-524. doi:
10.1039/d3tb01595e. [PMID: 38108579] - Ma Yingjun, Tang Shuo, Jiang Liuyun, Zhang Yan, Su Shengpei. Study on a co-hybrid nano-hydroxyapatite with lignin derivatives and alendronate and the reinforce effect for poly(lactide-co-glycolide).
International journal of biological macromolecules.
2023 Sep; 253(Pt 2):126785. doi:
10.1016/j.ijbiomac.2023.126785. [PMID: 37696379] - Huanhuan Yan, Chen Wang, Qingxia Zhang, Pengfei Yu, Yuwei Xiao, Chunhua Wang, Peibiao Zhang, Guige Hou. Conductive Polyaniline Particles Regulating In Vitro Hydrolytic Degradation and Erosion of Hydroxyapatite/Poly(lactide-co-glycolide) Porous Scaffolds for Bone Tissue Engineering.
ACS biomaterials science & engineering.
2023 03; 9(3):1541-1557. doi:
10.1021/acsbiomaterials.2c01253. [PMID: 36758235] - Eveen Al-Shalabi, Samah Abusulieh, Alaa M Hammad, Suhair Sunoqrot. Rhoifolin loaded in PLGA nanoparticles alleviates oxidative stress and inflammation in vitro and in vivo.
Biomaterials science.
2022 Sep; 10(19):5504-5519. doi:
10.1039/d2bm00309k. [PMID: 35920694] - Hamide Sena Ozbay, Samiye Yabanoglu-Ciftci, Ipek Baysal, Merve Gultekinoglu, Cemil Can Eylem, Kezban Ulubayram, Emirhan Nemutlu, Rezan Topaloglu, Fatih Ozaltin. Mitochondria-targeted CoQ10 loaded PLGA-b-PEG-TPP nanoparticles: Their effects on mitochondrial functions of COQ8B-/- HK-2 cells.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2022 Apr; 173(?):22-33. doi:
10.1016/j.ejpb.2022.02.018. [PMID: 35231556] - Seong Ik Jeon, Moo Song Kim, Hyung Jun Kim, Young Il Kim, Hwan Jun Jae, Cheol-Hee Ahn. Biodegradable poly(lactide-co-glycolide) microspheres encapsulating hydrophobic contrast agents for transarterial chemoembolization.
Journal of biomaterials science. Polymer edition.
2022 03; 33(4):409-425. doi:
10.1080/09205063.2021.1990472. [PMID: 34613885] - Lan Wu, Lin-Ping Wu, Jingya Wu, Jin Sun, Zhonggui He, Cristina Rodríguez-Rodríguez, Katayoun Saatchi, Lea Ann Dailey, Urs O Häfeli, Dongmei Cun, Mingshi Yang. Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.
ACS applied materials & interfaces.
2021 Jan; 13(3):3722-3737. doi:
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Biomaterials.
2021 01; 267(?):120389. doi:
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Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2021 01; 19(1):32-37. doi:
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International journal of biological macromolecules.
2020 Oct; 160(?):142-152. doi:
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Journal of biomaterials science. Polymer edition.
2020 06; 31(9):1107-1126. doi:
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Gastroenterology.
2020 05; 158(6):1667-1681.e12. doi:
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AAPS PharmSciTech.
2020 Jan; 21(3):85. doi:
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Journal of materials chemistry. B.
2020 01; 8(4):655-665. doi:
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Journal of biomedical materials research. Part B, Applied biomaterials.
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International journal for parasitology. Drugs and drug resistance.
2019 12; 11(?):148-155. doi:
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Cardiovascular and interventional radiology.
2019 Aug; 42(8):1175-1182. doi:
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Cell chemical biology.
2019 05; 26(5):623-633.e9. doi:
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Food chemistry.
2019 Mar; 276(?):467-474. doi:
10.1016/j.foodchem.2018.10.016. [PMID: 30409621] - Laiba Arshad, Ibrahim Jantan, Syed Nasir Abbas Bukhari. Enhanced immunosuppressive effects of 3,5-bis[4(diethoxymethyl)benzylidene]-1-methyl-piperidin-4-one, an α, β-unsaturated carbonyl-based compound as PLGA-b-PEG nanoparticles.
Drug design, development and therapy.
2019; 13(?):1421-1436. doi:
10.2147/dddt.s185191. [PMID: 31118577] - Hongjuan Zhang, Chenguang Pu, Qiao Wang, Xinyi Tan, Jingxin Gou, Haibing He, Yu Zhang, Tian Yin, Yanjiao Wang, Xing Tang. Physicochemical Characterization and Pharmacokinetics of Agomelatine-Loaded PLGA Microspheres for Intramuscular Injection.
Pharmaceutical research.
2018 Nov; 36(1):9. doi:
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Biomaterials science.
2018 Sep; 6(10):2681-2693. doi:
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International journal of pharmaceutics.
2018 Sep; 548(2):747-758. doi:
10.1016/j.ijpharm.2017.10.032. [PMID: 29042337] - Jude Akinyelu, Moganavelli Singh. Chitosan Stabilized Gold-Folate-Poly(lactide-co-glycolide) Nanoplexes Facilitate Efficient Gene Delivery in Hepatic and Breast Cancer Cells.
Journal of nanoscience and nanotechnology.
2018 Jul; 18(7):4478-4486. doi:
10.1166/jnn.2018.15286. [PMID: 29442622] - Hye Seung Woo, Sung Rae Kim, Mikyeong Yoon, Eun Seok Lee, In Ho Chang, Young Mi Whang, Do Ik Lee, Myung Joo Kang, Young Wook Choi. Combined Poly(Lactide-Co-Glycolide) Microspheres Containing Diphtheria Toxoid for a Single-shot Immunization.
AAPS PharmSciTech.
2018 Apr; 19(3):1160-1167. doi:
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Journal of cellular biochemistry.
2017 12; 118(12):4203-4209. doi:
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International journal of pharmaceutics.
2017 Nov; 533(2):389-401. doi:
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2017 Oct; 11(1):292. doi:
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Scientific reports.
2017 09; 7(1):11247. doi:
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British journal of clinical pharmacology.
2017 07; 83(7):1476-1498. doi:
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JSLS : Journal of the Society of Laparoendoscopic Surgeons.
2017 Jul; 21(3):. doi:
10.4293/jsls.2017.00029. [PMID: 28729782] - Vukoman Jokanović, Božana Čolović, Dejan Marković, Milan Petrović, Ivan Soldatović, Djordje Antonijević, Petar Milosavljević, Nikola Sjerobabin, Jelena Sopta. Extraordinary biological properties of a new calcium hydroxyapatite/poly(lactide-co-glycolide)-based scaffold confirmed by in vivo investigation.
Biomedizinische Technik. Biomedical engineering.
2017 May; 62(3):295-306. doi:
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2017 03; 249(?):183-195. doi:
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Veterinary surgery : VS.
2017 Feb; 46(2):306-315. doi:
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Oncotarget.
2016 11; 7(47):76635-76646. doi:
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2016 Nov; 41(22):4254-4258. doi:
10.4268/cjcmm20162227. [PMID: 28933097] - Jeong-Jun Lee, Song Yi Lee, Ju-Hwan Park, Dae-Duk Kim, Hyun-Jong Cho. Cholesterol-modified poly(lactide-co-glycolide) nanoparticles for tumor-targeted drug delivery.
International journal of pharmaceutics.
2016 Jul; 509(1-2):483-491. doi:
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Journal of biomaterials science. Polymer edition.
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Acta pharmacologica Sinica.
2016 Jun; 37(6):834-44. doi:
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Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
2016 Feb; 14(1):103-5. doi:
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Drug design, development and therapy.
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2014 Nov; 6(23):14270-9. doi:
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Biomaterials.
2014 Nov; 35(33):9199-207. doi:
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Pharmaceutical research.
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Expert opinion on drug delivery.
2014 Sep; 11(9):1367-80. doi:
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Anti-cancer drugs.
2014 Jul; 25(6):641-51. doi:
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Biomacromolecules.
2014 May; 15(5):1586-92. doi:
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Nanoscale.
2014 Mar; 6(6):3250-8. doi:
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Cancer research.
2014 Mar; 74(6):1670-81. doi:
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International journal of molecular sciences.
2014 Feb; 15(3):3373-88. doi:
10.3390/ijms15033373. [PMID: 24573250] - Yueh-Lung Yang, Ching-Hsien Chang, Ching-Cheng Huang, Wenny Mei-Wen Kao, Wei-Chung Liu, Hsia-Wei Liu. Osteogenic activity of nanonized pearl powder/poly (lactide-co-glycolide) composite scaffolds for bone tissue engineering.
Bio-medical materials and engineering.
2014; 24(1):979-85. doi:
10.3233/bme-130893. [PMID: 24211987] - Shih-shiung Huang, I-Hsun Li, Po-da Hong, Ming-kung Yeh. Development of Yersinia pestis F1 antigen-loaded microspheres vaccine against plague.
International journal of nanomedicine.
2014; 9(?):813-22. doi:
10.2147/ijn.s56260. [PMID: 24550673] - Antonia Terriza, Jose I Vilches-Pérez, Emilio de la Orden, Francisco Yubero, Juan L Gonzalez-Caballero, Agustin R González-Elipe, José Vilches, Mercedes Salido. Osteoconductive potential of barrier nanoSiO2 PLGA membranes functionalized by plasma enhanced chemical vapour deposition.
BioMed research international.
2014; 2014(?):253590. doi:
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Journal of microencapsulation.
2014; 31(3):239-45. doi:
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Journal of pharmaceutical sciences.
2013 Nov; 102(11):4140-9. doi:
10.1002/jps.23735. [PMID: 24114868] - Raman Preet Singh, Poduri Ramarao. Accumulated polymer degradation products as effector molecules in cytotoxicity of polymeric nanoparticles.
Toxicological sciences : an official journal of the Society of Toxicology.
2013 Nov; 136(1):131-43. doi:
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European cells & materials.
2013 Oct; 26(?):179-94; discussion 194. doi:
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Journal of plastic, reconstructive & aesthetic surgery : JPRAS.
2013 Jun; 66(6):835-8. doi:
10.1016/j.bjps.2013.02.006. [PMID: 23558021] - Heran Wang, Min Li, Jianming Hu, Chenhong Wang, Shanshan Xu, Charles C Han. Multiple targeted drugs carrying biodegradable membrane barrier: anti-adhesion, hemostasis, and anti-infection.
Biomacromolecules.
2013 Apr; 14(4):954-61. doi:
10.1021/bm301997e. [PMID: 23448620] - Mingbin Zheng, Caixia Yue, Yifan Ma, Ping Gong, Pengfei Zhao, Cuifang Zheng, Zonghai Sheng, Pengfei Zhang, Zhaohui Wang, Lintao Cai. Single-step assembly of DOX/ICG loaded lipid--polymer nanoparticles for highly effective chemo-photothermal combination therapy.
ACS nano.
2013 Mar; 7(3):2056-67. doi:
10.1021/nn400334y. [PMID: 23413798] - Romie F Gibly, Xiaomin Zhang, William L Lowe, Lonnie D Shea. Porous scaffolds support extrahepatic human islet transplantation, engraftment, and function in mice.
Cell transplantation.
2013; 22(5):811-9. doi:
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International journal of nanomedicine.
2013; 8(?):3161-9. doi:
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Colloids and surfaces. B, Biointerfaces.
2013 Jan; 101(?):353-60. doi:
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Biomaterials.
2012 Oct; 33(28):6769-82. doi:
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International journal of pharmaceutics.
2012 Aug; 433(1-2):102-11. doi:
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Journal of dental research.
2012 Jun; 91(6):618-24. doi:
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2012 May; 81(1):57-63. doi:
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Acta biomaterialia.
2012 Mar; 8(3):1303-15. doi:
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Vaccine.
2012 Jan; 30(3):589-96. doi:
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Platelets.
2012; 23(8):594-603. doi:
10.3109/09537104.2011.645923. [PMID: 22273512] - Hong Zhang, Yunhui Zhao, Fengxuan Han, Min Wang, Xiaoyan Yuan. Controlled release of bovine serum albumin from electrospun fibrous membranes via an improved emulsion-core technique.
Journal of controlled release : official journal of the Controlled Release Society.
2011 Nov; 152 Suppl 1(?):e181-2. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Jul; 879(21):1967-72. doi:
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The Journal of cardiovascular surgery.
2011 Apr; 52(2):159-67. doi:
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Journal of nanoscience and nanotechnology.
2011 Feb; 11(2):1795-8. doi:
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The International journal of artificial organs.
2011 Feb; 34(2):249-52. doi:
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Veterinary surgery : VS.
2011 Feb; 40(2):223-7. doi:
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Ophthalmic research.
2011; 46(2):55-65. doi:
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International journal of nanomedicine.
2011; 6(?):3049-56. doi:
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International journal of pharmaceutics.
2010 Dec; 402(1-2):165-74. doi:
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European urology.
2010 Dec; 58(6):875-81. doi:
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International journal of nanomedicine.
2010 Nov; 5(?):1039-48. doi:
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Biomacromolecules.
2010 Nov; 11(11):2993-9. doi:
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International journal of pharmaceutics.
2010 Sep; 397(1-2):122-9. doi:
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Experimental biology and medicine (Maywood, N.J.).
2010 Jun; 235(6):678-88. doi:
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Biomaterials.
2010 May; 31(15):4353-9. doi:
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Anti-cancer drugs.
2010 Jan; 21(1):43-52. doi:
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Transplantation proceedings.
2009 Dec; 41(10):4044-6. doi:
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Current drug delivery.
2009 Oct; 6(5):495-504. doi:
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