Ethyl 2-(5-(4-chlorophenyl)pentyl)oxiran-2-carboxylate (BioDeep_00000182523)

   

human metabolite blood metabolite


代谢物信息卡片


Ethyl 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylic acid

化学式: C16H21ClO3 (296.1179146)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOC(=O)C1(CCCCCC2=CC=C(Cl)C=C2)CO1
InChI: InChI=1S/C16H21ClO3/c1-2-19-15(18)16(12-20-16)11-5-3-4-6-13-7-9-14(17)10-8-13/h7-10H,2-6,11-12H2,1H3

描述信息

D007004 - Hypoglycemic Agents

同义名列表

4 个代谢物同义名

Ethyl 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylic acid; Ethyl 2-(5-(4-chlorophenyl)pentyl)oxiran-2-carboxylic acid; ethyl 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate; Ethyl 2-(5-(4-chlorophenyl)pentyl)oxiran-2-carboxylate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Simona M Ceccarelli, Odile Chomienne, Marcel Gubler, Arduino Arduini. Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. Journal of medicinal chemistry. 2011 May; 54(9):3109-52. doi: 10.1021/jm100809g. [PMID: 21504156]
  • G Schmilinsky-Fluri, V Valiunas, M Willi, R Weingart. Modulation of cardiac gap junctions: the mode of action of arachidonic acid. Journal of molecular and cellular cardiology. 1997 Jun; 29(6):1703-13. doi: 10.1006/jmcc.1997.0409. [PMID: 9220356]
  • M van Bilsen, G J van der Vusse, P H Willemsen, W A Coumans, R S Reneman. Fatty acid accumulation during ischemia and reperfusion: effects of pyruvate and POCA, a carnitine palmitoyltransferase I inhibitor. Journal of molecular and cellular cardiology. 1991 Dec; 23(12):1437-47. doi: 10.1016/0022-2828(91)90189-s. [PMID: 1811059]
  • A Chicco, R Gutman, Y B Lombardo. Biochemical abnormalities in the heart of rats fed a sucrose-rich diet: is the low activity of the pyruvate dehydrogenase complex a result of increased fatty acid oxidation?. Metabolism: clinical and experimental. 1991 Jan; 40(1):15-21. doi: 10.1016/0026-0495(91)90185-y. [PMID: 1984563]
  • T R DeGrado, J E Holden, C K Ng, D M Raffel, S J Gatley. Quantitative analysis of myocardial kinetics of 15-p-[iodine-125] iodophenylpentadecanoic acid. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1989 Jul; 30(7):1211-8. doi: ". [PMID: 2738702]
  • A K Bhuiyan, K Bartlett, H S Sherratt, L Agius. Effects of ciprofibrate and 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate (POCA) on the distribution of carnitine and CoA and their acyl-esters and on enzyme activities in rats. Relation between hepatic carnitine concentration and carnitine acetyltransferase activity. The Biochemical journal. 1988 Jul; 253(2):337-43. doi: 10.1042/bj2530337. [PMID: 3178716]
  • P Rösen, H Reinauer. Influence of the carnitine palmitoyltransferase inhibitor POCA on myocardial performance and metabolism of insulin resistant rats. Acta physiologica Hungarica. 1988; 71(2):271-80. doi: ". [PMID: 3389170]
  • J Vamecq, F Roels, C Van den Branden, J P Draye. Peroxisomal proliferation in heart and liver of mice receiving chlorpromazine, ethyl 2(5(4-chlorophenyl)pentyl) oxiran-2-carboxylic acid or high fat diet: a biochemical and morphometrical comparative study. Pediatric research. 1987 Dec; 22(6):748-54. doi: 10.1203/00006450-198712000-00027. [PMID: 3431962]
  • P Rösen, L Herberg, H Reinauer. Different types of postinsulin receptor defects contribute to insulin resistance in hearts of obese Zucker rats. Endocrinology. 1986 Sep; 119(3):1285-91. doi: 10.1210/endo-119-3-1285. [PMID: 3732168]
  • P P Koundakjian, D M Turnbull, A J Bone, M P Rogers, S I Younan, H S Sherratt. Metabolic changes in fed rats caused by chronic administration of ethyl 2[5(4-chlorophenyl)pentyl]oxirane-2-carboxylate, a new hypoglycaemic compound. Biochemical pharmacology. 1984 Feb; 33(3):465-73. doi: 10.1016/0006-2952(84)90242-9. [PMID: 6231030]
  • H S Sherratt, R K Veitch. Animal models for dicarboxylic aciduria. Journal of inherited metabolic disease. 1984; 7 Suppl 1(?):52-6. doi: 10.1007/bf03047375. [PMID: 6434846]