Ribavirin (BioDeep_00000018223)

   

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide

化学式: C8H12N4O5 (244.08076619999997)
中文名称: 利巴韦林
谱图信息: 最多检出来源 Homo sapiens(blood) 94.74%

分子结构信息

SMILES: C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
InChI: InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1

描述信息

Ribavirin is only found in individuals that have used or taken this drug. It is a nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses. [PubChem]Ribavirin is readily phosphorylated intracellularly by adenosine kinase to ribavirin mono-, di-, and triphosphate metabolites. Ribavirin triphosphate (RTP) is a potent competitive inhibitor of inosine monophosphate (IMP) dehydrogenase, viral RNA polymerase and messenger RNA (mRNA) guanylyltransferase (viral) and can be incorporated into RNA in RNA viral species. Guanylyltranserase inhibition stops the capping of mRNA. These diverse effects result in a marked reduction of intracellular guanosine triphosphate (GTP) pools and inhibition of viral RNA and protein synthesis. Ribavirin is also incorporated into the viral genome causing lethal mutagenesis and a subsequent decrease in specific viral infectivity.
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AP - Antivirals for treatment of hcv infections
COVID info from Guide to PHARMACOLOGY, clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
C254 - Anti-Infective Agent > C281 - Antiviral Agent
D009676 - Noxae > D000963 - Antimetabolites
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

同义名列表

33 个代谢物同义名

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide; 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; 1-Β-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; 1-b-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide; 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide; 1-pentofuranosyl-1h-1,2,4-triazole-3-carboxamide; 1-Β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide; Three rivers pharmaceuticals brand OF ribavirin; Dermatech brand OF ribavirin; Grossman brand OF ribavirin; Pfizer brand OF ribavirin; Merck brand OF ribavirin; Essex brand OF ribavirin; ICN brand OF ribavirin; Ribavirin merck brand; Ribavirinum; Tribavirin; Ribasphere; Ribavirina; Ribavirine; Ribamidil; Ribovirin; Ribavirin; Ribamidyl; Ribamide; Virazide; Virazole; Viramide; Rebetol; Copegus; Vilona; RBV



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jun-Yu Xi, Zhong-Yi Wei, Qiang Zhang, Yan-Ming Xie. [Clinical comprehensive evaluation of Houyanqing Oral Liquid in treatment of acute pharyngitis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Jan; 49(1):279-284. doi: 10.19540/j.cnki.cjcmm.20230918.501. [PMID: 38403360]
  • Haiyan Zhao, Hongfu He, Zhongjie Shen, Chunle Wei, Limin Yin, Yunying Zhu, Hongxia Lu, Runjiang Song, Deyu Hu. Development and Mechanism Investigation of Novel Thioacetalized Indoles as Antiphytoviral Agents. Journal of agricultural and food chemistry. 2023 Nov; 71(46):17658-17668. doi: 10.1021/acs.jafc.3c03967. [PMID: 37937740]
  • Guang-Long Zhang, Zhen-Chao Wang, Cheng-Peng Li, Dan-Ping Chen, Zhu-Rui Li, Yan Li, Gui-Ping Ouyang. Discovery of tryptanthrin analogues bearing F and piperazine moieties as novel phytopathogenic antibacterial and antiviral agents. Pest management science. 2023 Oct; ?(?):. doi: 10.1002/ps.7834. [PMID: 37842924]
  • Jiří Sedlák, Jaroslava Přibylová, Igor Koloňuk, Josef Špak, Ondřej Lenz, Matěj Semerák. Elimination of Solanum nigrum ilarvirus 1 and Apple Hammerhead Viroid from Apple Cultivars Using Antivirals Ribavirin, Rimantadine, and Zidovudine. Viruses. 2023 Aug; 15(8):. doi: 10.3390/v15081684. [PMID: 37632025]
  • Ziwei Guo, Huan He, Kunqian Liu, Zihui Li, Shicheng Yang, Zhicheng Liao, Chaochao Lai, Xiaomin Ren, Bin Huang, Xuejun Pan. The photolytic behavior of COVID-19 antivirals ribavirin in natural waters and the increased environmental risk. Journal of hazardous materials. 2023 06; 452(?):131320. doi: 10.1016/j.jhazmat.2023.131320. [PMID: 37002997]
  • Ganlan Zhang, Hui Liu, Ting Xue, Xiangming Kong, Dongmei Tian, Libo Luo, Yanhua Yang, Keqing Xu, Youheng Wei, Ziheng Zhuang. Ribavirin extends the lifespan of Caenorhabditis elegans through AMPK-TOR Signaling. European journal of pharmacology. 2023 May; 946(?):175548. doi: 10.1016/j.ejphar.2023.175548. [PMID: 36706801]
  • Yongyue Gao, Xingxing He, Lili Yan, Hongyu Zhang, Sijia Liu, Qian Ma, Peiyao Zhang, Yan Zhang, Zijun Zhang, Ziwen Wang, Aidang Lu, Qingmin Wang. Discovery of Barakacin and Its Derivatives as Novel Antiviral and Fungicidal Agents. Molecules (Basel, Switzerland). 2023 Mar; 28(7):. doi: 10.3390/molecules28073032. [PMID: 37049795]
  • Yicheng Wang, Jiaxiu Sun, Jingke Wang, Shrestha Sujata, Qianru Huang, Caiting Hou, Yunfeng Wu, Lei Zhao. Efficient Elimination of Actinidia Chlorotic Ringspot-Associated Virus from Infected Kiwifruit Shoots Cultured In Vitro. Plant disease. 2023 Jan; 107(1):34-37. doi: 10.1094/pdis-05-22-1101-sc. [PMID: 35787011]
  • Zongwei Xia, Xiuling Yu, Feng Feng, Pengfei Song, Wenqiang Yang, Jiacai Wang, Qingmin Wang. Discovery of Resveratrol and its Derivatives as Novel Antiviral and Anti- Phytopathogenic-Fungus Agents. Current organic synthesis. 2023; 20(3):351-359. doi: 10.2174/1570179420666221005124445. [PMID: 36200163]
  • Meiling Yuan, Zhaoyong Tian, Xiangyang Yin, Xinyu Yuan, Jixuan Gao, Wenying Yuan, Aidang Lu, Ziwen Wang, Liang Li, Qingmin Wang. Structural Optimization of the Natural Product: Discovery of Almazoles C-D and Their Derivatives as Novel Antiviral and Anti-phytopathogenic Fungus Agents. Journal of agricultural and food chemistry. 2022 Dec; 70(50):15693-15702. doi: 10.1021/acs.jafc.2c05898. [PMID: 36479881]
  • Yucong Ma, Lu Wang, Aidang Lu, Wei Xue. Synthesis and Biological Activity of Novel Oxazinyl Flavonoids as Antiviral and Anti-Phytopathogenic Fungus Agents. Molecules (Basel, Switzerland). 2022 Oct; 27(20):. doi: 10.3390/molecules27206875. [PMID: 36296469]
  • Hong-Wei He, Fei-Yu Wang, Danyang Zhang, Cai-Yun Chen, Dan Xu, Huan Zhou, Xili Liu, Gong Xu. Discovery of Novel α-Methylene-γ-Butyrolactone Derivatives Containing Vanillin Moieties as Antiviral and Antifungal Agents. Journal of agricultural and food chemistry. 2022 Aug; 70(33):10316-10325. doi: 10.1021/acs.jafc.2c03632. [PMID: 35960686]
  • Wei-Feng Li, Chan-Chan Hu, Ya-Li Ding, Bin Yuan. [Overview of Meta-analysis of Lianhua Qingwen preparations in treatment of viral diseases]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2022 Aug; 47(16):4505-4516. doi: 10.19540/j.cnki.cjcmm.20220510.501. [PMID: 36046880]
  • L I Nikolaeva, A N Belyavtsev, N G Shevchenko, M D Stuchinskaya, E I Samokhvalov, A V Dedova, G V Sapronov, N S Shastina, V V Kuprianov. [The analysis of immunoreactivity of individual B-cell epitopes of hepatitis C virus (Flaviviridae: Hepacivirus: Hepatitis С virus) NS4a antigen]. Voprosy virusologii. 2022 Jul; 67(3):237-245. doi: 10.36233/0507-4088-115. [PMID: 35831966]
  • Xenia Bacinschi, Gabriel Cristian Popescu, Anca Zgura, Laurentia Gales, Anghel Rodica, Adriana Mercan, Dragos Serban, Bogdan Haineala, Letitia Toma, Laura Iliescu. A Real-World Study to Compare the Safety and Efficacy of Paritaprevir/Ombitasvir/Ritonavir and Dasabuvir, with or without Ribavirin, in 587 Patients with Chronic Hepatitis C at the Fundeni Clinical Institute, Bucharest, Romania. Medical science monitor : international medical journal of experimental and clinical research. 2022 Jul; 28(?):e936706. doi: 10.12659/msm.936706. [PMID: 35787600]
  • Liang Liu, Sixun Guo, Chunli Che, Quanming Su, Deqiu Zhu, Xin Hai. Improved HPLC method for the determination of ribavirin concentration in red blood cells and its application in patients with COVID-19. Biomedical chromatography : BMC. 2022 Jul; 36(7):e5370. doi: 10.1002/bmc.5370. [PMID: 35297066]
  • Tomoaki Hasegawa, Sono Sawada, Chieko Ishiguro, Takashi Ando, Kanae Kobayashi, Noriyuki Komiyama, Toyotaka Iguchi, Takahiro Nonaka, Yoshiaki Uyama. Assessing the Risk of Decrease in Kidney Function in Patients Prescribed Direct-Acting Antivirals for Hepatitis C Utilizing the MID-NET® Medical Information Database Network in Japan. Therapeutic innovation & regulatory science. 2022 07; 56(4):625-631. doi: 10.1007/s43441-022-00400-5. [PMID: 35437631]
  • Yi-Kai Wang, Ying-Wen Wang, Chia-Ling Lu, Yi-Hsiang Huang, Ming-Chih Hou, Yuh-Lih Chang, Wei-Ping Lee, Keng-Hsin Lan. Sofosbuvir-based direct-acting antivirals and changes in cholesterol and low density lipoprotein-cholesterol. Scientific reports. 2022 06; 12(1):9942. doi: 10.1038/s41598-022-13657-5. [PMID: 35705594]
  • Marco Antonio Motisi, Agnese Tamborino, Sara Parigi, Luisa Galli, Maurizio de Martino, Elena Chiappini. The use of antiviral drugs in children. Journal of chemotherapy (Florence, Italy). 2022 Apr; 34(2):73-86. doi: 10.1080/1120009x.2021.1979746. [PMID: 34633268]
  • Dongzhi Li, Chengshuai He, Meizi Wang, Hongyu Liu, Runqiang Liu, Li Xu. Toxicity of Ribavirin to Spodoptera litura by Inhibiting the Juvenile Hormone. Journal of agricultural and food chemistry. 2022 Mar; 70(10):3117-3126. doi: 10.1021/acs.jafc.1c06172. [PMID: 35229607]
  • Lone W Madsen, Peer B Christensen, Janne F Hansen, Birgit T Røge, Dorte K Holm, Sandra Dröse, Anne Øvrehus. Four Weeks Treatment with Glecaprevir/Pibrentasvir + Ribavirin-A Randomized Controlled Clinical Trial. Viruses. 2022 03; 14(3):. doi: 10.3390/v14030614. [PMID: 35337021]
  • Mohamed Abdel-Salam Elgohary, Eman Medhat Hasan, Amany Ahmad Ibrahim, Mohamed Farouk Ahmed Abdelsalam, Raafat Zaher Abdel-Rahman, Ashraf Ibrahim Zaki, Mohamed Bakr Elaatar, Mohamed Thabet Elnagar, Mohamed Emam Emam, Mahmoud Moustafa Hamada, Taimour Mohamed Abdel-Hamid, Ahmad Samir Abdel-Hafez, Mohamed Gomaa Seadawy, Ahmad Rashad Fatoh, Mohamed Ali Elsaied, Marwa Abdel-Rahman Sakr, Ahmed Omar Elkady, Mohamed Muawad Shehata, Osama Mohamed Nawar, Mohamed Abu-Elnaga Selem, Mohamed Saeed Abd-Aal, Hany Hafez Lotfy, Tarek Refaat Elnagdy, Sherine Helmy, Magdy Amin Mubark. Efficacy of Sofosbuvir plus Ledipasvir in Egyptian patients with COVID-19 compared to standard treatment: a randomized controlled trial. Journal of medicine and life. 2022 Mar; 15(3):350-358. doi: 10.25122/jml-2021-0175. [PMID: 35449996]
  • Alex P Salam, Alexandre Duvignaud, Marie Jaspard, Denis Malvy, Miles Carroll, Joel Tarning, Piero L Olliaro, Peter W Horby. Ribavirin for treating Lassa fever: A systematic review of pre-clinical studies and implications for human dosing. PLoS neglected tropical diseases. 2022 03; 16(3):e0010289. doi: 10.1371/journal.pntd.0010289. [PMID: 35353804]
  • Cheng-Kun Wu, Li-Wei Chen, Te-Sheng Chang, Shui-Yi Tung, Chun-Yen Lin, Chao-Hung Hung, Sheng-Nan Lu, Chih-Lang Lin, Chien-Hung Chen, Chao-Wei Hsu, Tsung-Hui Hu, I-Shyan Sheen. The Novel Finding of Dynamic Change in eGFR Up to One Year after End of Treatment in HCV-Infected Patients Receiving Sofosbuvir and Velpatasvir. Viruses. 2022 02; 14(2):. doi: 10.3390/v14020362. [PMID: 35215955]
  • Ismail Celik, Meryem Erol, Zekeriya Duzgun. In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase. Molecular diversity. 2022 Feb; 26(1):279-292. doi: 10.1007/s11030-021-10215-5. [PMID: 33765239]
  • Kerstin Stein, Albrecht Stoehr, Hartwig Klinker, Gerlinde Teuber, Uwe Naumann, Christine John, Renate Heyne, Yvonne Serfert, Claus Niederau, Stefan Zeuzem, Thomas Berg, Johannes Wiegand. Hepatitis C therapy with grazoprevir/elbasvir and glecaprevir/pibrentasvir in patients with advanced chronic kidney disease: data from the German Hepatitis C-Registry (DHC-R). European journal of gastroenterology & hepatology. 2022 01; 34(1):76-83. doi: 10.1097/meg.0000000000001923. [PMID: 32956186]
  • Michael D Waters, Stafford Warren, Claude Hughes, Philip Lewis, Fengyu Zhang. Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: The special case of molnupiravir. Environmental and molecular mutagenesis. 2022 01; 63(1):37-63. doi: 10.1002/em.22471. [PMID: 35023215]
  • Jinyu Liu, Min Guo, Lei Ke, Ruxu You. Cost-Effectiveness of Elbasvir/Grazoprevir for the Treatment of Chronic Hepatitis C: A Systematic Review. Frontiers in public health. 2022; 10(?):836986. doi: 10.3389/fpubh.2022.836986. [PMID: 35646774]
  • Phuong Nguyen Thi Thu, Mai Ngo Thi Quynh, Linh Pham Van, Hung Nguyen Van, Hoi Nguyen Thanh. Determination of Risk Factors Associated with the Failure of 12 Weeks of Direct-Acting Antiviral Therapy in Patients with Hepatitis C: A Prospective Study. BioMed research international. 2022; 2022(?):6054677. doi: 10.1155/2022/6054677. [PMID: 35572735]
  • Chen-Hua Liu, Chi-Yi Chen, Wei-Wen Su, Kuo-Chih Tseng, Ching-Chu Lo, Chun-Jen Liu, Jyh-Jou Chen, Cheng-Yuan Peng, Yu-Lueng Shih, Sheng-Shun Yang, Chia-Sheng Huang, Ke-Jhang Huang, Chi-Yang Chang, Ming-Chang Tsai, Wei-Yu Kao, Yo-Jen Fang, Po-Yueh Chen, Pei-Yuan Su, Chih-Wei Tseng, Jow-Jyh Huang, Pei-Lun Lee, Hsueh-Chou Lai, Tsai-Yuan Hsieh, Chung-Hsin Chang, Yi-Jie Huang, Fu-Jen Lee, Chun-Chao Chang, Jia-Horng Kao. Sofosbuvir/velpatasvir with or without low-dose ribavirin for patients with chronic hepatitis C virus infection and severe renal impairment. Gut. 2022 01; 71(1):176-184. doi: 10.1136/gutjnl-2020-323569. [PMID: 33408122]
  • Tianhang Chen, Haixia Du, Huifen Zhou, Jiehong Yang, Jiaqi Zhu, Xin Tong, Yuting Yang, Jiayang Wan, Yichen Fan, Yiyu Lu, Yu He, Haitong Wan. Screening of Antiviral Components of Yinhuapinggan Granule and Protective Effects of Yinhuapinggan Granule on MDCK Cells with Influenza A/H1N1 Virus. BioMed research international. 2022; 2022(?):1040129. doi: 10.1155/2022/1040129. [PMID: 35211622]
  • M Haroon Hamed, Peter Natesan Pushparaj, Shafiqur Rehman, Saleh Al-Karim, Salem Bazarah, Ishtiaq Qadri. Deciphering the Significance of Plasma Chemokines as Prognostic Biomarkers in Pegylated IFN-Α-2a /Ribavirin-Treated Chronic Hepatitis C Genotype 4 Patients. Infectious disorders drug targets. 2022; 22(5):58-62. doi: 10.2174/1871526522666220303142837. [PMID: 35240967]
  • Mahmoud Abdo, Ahmed Rabiee, Zeinab Abdellatif, Shereen Abdel Alem, Ahmed Moustafa. Impact of sustained virological response on metabolic disorders in diabetic chronic hepatitis C virus patients after treatment with generic sofosbuvir and daclatasvir. European journal of gastroenterology & hepatology. 2021 12; 33(12):1588-1594. doi: 10.1097/meg.0000000000001903. [PMID: 32804853]
  • Gina Gamal Naguib, Amir Farid, Mohamed Hassan, Ahmed Elshafie, Yehia El Shazly, Mohamed Kamal Shaker, Haitham Ezzat, Eslam Safwat, Ossama Ashraf Ahmed, Hany Dabbous, Ahmed Fouad Sherief, Mohamed Hassany, Magdy Elserafy, Manal Hamdy Elsayed. Direct-acting antiviral regimens in Egyptian patients with chronic hepatitis C virus infection: A real-world single-center experience. Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology. 2021 Dec; 22(4):285-291. doi: 10.1016/j.ajg.2021.06.001. [PMID: 34531135]
  • Q Xu, W Zhang, Y X Ma, C N He, L T Zhang, Yilihamu Abulitifu, Y Li, N Wang, H L Wang, Y Y Zhao, X Gao, P G Gao, X Y Su, S Li, Y Y Liu, F Guo, Z Q Chen, H L Liu, X Q Gao, J J Fu, G Y Yu, X Z Wang, J P Wang, Y P Zhang, F P Ji. [Twelve-week of sofosbuvir/velpatasvir therapeutic regimen for chronic hepatitis C patients in northwest region of China: a real-world multicenter clinical study]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. 2021 Nov; 29(11):1046-1052. doi: 10.3760/cma.j.cn501113-20201010-00548. [PMID: 34933421]
  • Hanuman Prasad Sharma, Nabanita Halder, Sundararajan Baskar Singh, T Velpandian. Evaluation of the Presence and Functional Importance of Nucleoside Transporters in Lacrimal Gland for Tear Disposition of Intravenously Injected Substrate in Rabbits. Current eye research. 2021 11; 46(11):1659-1665. doi: 10.1080/02713683.2021.1925698. [PMID: 33941003]
  • Fabrizio Fabrizi, Cristina Alonso, Ana Palazzo, Margarita Anders, Maria Virginia Reggiardo, Hugo Cheinquer, Maria Grazia Videla Zuain, Sebastian Figueroa, Manuel Mendizabal, Marcelo Silva, Ezequiel Ridruejo. 'Real-life' experience with direct-acting antiviral agents for HCV after kidney transplant. Annals of hepatology. 2021 Nov; 25(?):100337. doi: 10.1016/j.aohep.2021.100337. [PMID: 33684523]
  • Yuewen Liu, Jixiang Chen, Dandan Xie, Baoan Song, Deyu Hu. First Report on Anti-TSWV Activities of Quinazolinone Derivatives Containing a Dithioacetal Moiety. Journal of agricultural and food chemistry. 2021 Oct; 69(41):12135-12142. doi: 10.1021/acs.jafc.1c03171. [PMID: 34623814]
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  • Adita Ayu Permanasari, Chie Aoki-Utsubo, Tutik Sri Wahyuni, Lidya Tumewu, Myrna Adianti, Aty Widyawaruyanti, Hak Hotta, Achmad Fuad Hafid. An in vitro study of an Artocarpus heterophyllus substance as a hepatitis C antiviral and its combination with current anti-HCV drugs. BMC complementary medicine and therapies. 2021 Oct; 21(1):260. doi: 10.1186/s12906-021-03408-w. [PMID: 34641875]
  • Xiaoyu Liu, Yuntao Hong, Shunke Ding, Wei Jin, Shengkun Dong, Rong Xiao, Wenhai Chu. Transformation of antiviral ribavirin during ozone/PMS intensified disinfection amid COVID-19 pandemic. The Science of the total environment. 2021 Oct; 790(?):148030. doi: 10.1016/j.scitotenv.2021.148030. [PMID: 34091342]
  • João Paulo Almirão de Jesus, Letícia Cristina Assis, Alexandre Alves de Castro, Elaine Fontes Ferreira da Cunha, Eugenie Nepovimova, Kamil Kuca, Teodorico de Castro Ramalho, Felipe de Almeida La Porta. Effect of drug metabolism in the treatment of SARS-CoV-2 from an entirely computational perspective. Scientific reports. 2021 10; 11(1):19998. doi: 10.1038/s41598-021-99451-1. [PMID: 34620963]
  • Ana Carrero, Juan Berenguer, Víctor Hontañón, Josep M Guardiola, Jordi Navarro, Miguel A von Wichmann, María J Téllez, Carmen Quereda, Ignacio Santos, José Sanz, María J Galindo, José Hernández-Quero, María A Jiménez-Sousa, Leire Pérez-Latorre, José M Bellón, Salvador Resino, Herminia Esteban, Esteban Martínez, Juan González-García. Effects of Hepatitis C Virus (HCV) Eradication on Bone Mineral Density in Human Immunodeficiency Virus/HCV-Coinfected Patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 10; 73(7):e2026-e2033. doi: 10.1093/cid/ciaa1396. [PMID: 32930720]
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  • Zeynep Gokce Gayretli Aydin, Osman Yesilbas, Gokce Pinar Reis, Burcu Guven. The first pediatric case of hemophagocytic lymphohistiocytosis secondary to Crimean-Congo haemorrhagic fever successfully treated with therapeutic plasma exchange accompanying ribavirin and intravenous immunoglobulin. Journal of clinical apheresis. 2021 Oct; 36(5):780-784. doi: 10.1002/jca.21915. [PMID: 34061376]
  • Jiangang Zheng, Yinlan Xu, Ajab Khan, Panpan Sun, Yaogui Sun, Kuohai Fan, Wei Yin, Shaoyu Wang, Hongquan Li, Na Sun. Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion. BMC veterinary research. 2021 Sep; 17(1):318. doi: 10.1186/s12917-021-03015-4. [PMID: 34587973]
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