Pentenyltetrazol (BioDeep_00000182222)
human metabolite blood metabolite
代谢物信息卡片
5-(pent-1-en-1-yl)-2H-1,2,3,4-tetrazole
化学式: C6H10N4 (138.090542)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC=CC1=NNN=N1
InChI: InChI=1S/C6H10N4/c1-2-3-4-5-6-7-9-10-8-6/h4-5H,2-3H2,1H3,(H,7,8,9,10)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
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PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Progress in neuro-psychopharmacology & biological psychiatry.
2012 Dec; 39(2):301-9. doi:
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Progress in neuro-psychopharmacology & biological psychiatry.
2012 Oct; 39(1):129-35. doi:
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European review for medical and pharmacological sciences.
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Journal of ethnopharmacology.
2012 Jun; 142(1):23-7. doi:
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Neurochemistry international.
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Vojnosanitetski pregled.
2012 Jun; 69(6):481-7. doi:
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2012 May; 141(1):220-7. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2012 May; 37(9):1307-10. doi:
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Epilepsy & behavior : E&B.
2012 May; 24(1):14-22. doi:
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2012 May; 99(3):225-32. doi:
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Journal of pharmacy & bioallied sciences.
2012 Apr; 4(2):140-8. doi:
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Journal of ethnopharmacology.
2012 Mar; 140(2):447-51. doi:
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BMC biology.
2012 Mar; 10(?):26. doi:
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Archives of pharmacal research.
2012 Mar; 35(3):423-30. doi:
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Brain research bulletin.
2012 Feb; 87(2-3):180-6. doi:
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Epilepsy research.
2012 Feb; 98(2-3):157-65. doi:
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Epilepsy research.
2012 Feb; 98(2-3):238-46. doi:
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Journal of ethnopharmacology.
2012 Jan; 139(1):273-9. doi:
10.1016/j.jep.2011.11.011. [PMID: 22107833] - Sung A Jung, Miseon Choi, Sohee Kim, Rina Yu, Taesun Park. Cinchonine Prevents High-Fat-Diet-Induced Obesity through Downregulation of Adipogenesis and Adipose Inflammation.
PPAR research.
2012; 2012(?):541204. doi:
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Indian journal of experimental biology.
2012 Jan; 50(1):51-5. doi:
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European journal of pharmacology.
2011 Dec; 673(1-3):33-9. doi:
10.1016/j.ejphar.2011.10.017. [PMID: 22044920] - Radha Goel, Amit Goel, Yatender Kumar. Influence of carvedilol on anticonvulsant effect of gabapentin.
Acta neurologica Belgica.
2011 Dec; 111(4):296-305. doi:
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Pediatric research.
2011 Dec; 70(6):584-8. doi:
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Epilepsy & behavior : E&B.
2011 Dec; 22(4):678-84. doi:
10.1016/j.yebeh.2011.09.021. [PMID: 22056341] - Maribel Herrera-Ruiz, Adolfo González-Carranza, Alejandro Zamilpa, Enrique Jiménez-Ferrer, Maira Huerta-Reyes, Víctor M Navarro-García. The standardized extract of Loeselia mexicana possesses anxiolytic activity through the γ-amino butyric acid mechanism.
Journal of ethnopharmacology.
2011 Nov; 138(2):261-7. doi:
10.1016/j.jep.2011.09.010. [PMID: 21979412] - M Herrera-Ruiz, A Zamilpa, M González-Cortazar, R Reyes-Chilpa, E León, M P García, J Tortoriello, M Huerta-Reyes. Antidepressant effect and pharmacological evaluation of standardized extract of flavonoids from Byrsonima crassifolia.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 Nov; 18(14):1255-61. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 Nov; 18(14):1250-4. doi:
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Epilepsia.
2011 Nov; 52(11):2094-104. doi:
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Journal of ethnopharmacology.
2011 Oct; 137(3):1431-6. doi:
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Journal of neuroinflammation.
2011 Oct; 8(?):135. doi:
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Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2011 Oct; 9(10):1118-24. doi:
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Journal of the neurological sciences.
2011 Sep; 308(1-2):35-40. doi:
10.1016/j.jns.2011.06.030. [PMID: 21737104] - K H Reeta, Jogender Mehla, Monika Pahuja, Yogendra Kumar Gupta. Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.
Pharmacology, biochemistry, and behavior.
2011 Sep; 99(3):399-407. doi:
10.1016/j.pbb.2011.05.011. [PMID: 21641922] - Monika Pahuja, Jogender Mehla, K H Reeta, Sujata Joshi, Yogendra Kumar Gupta. Hydroalcoholic extract of Zizyphus jujuba ameliorates seizures, oxidative stress, and cognitive impairment in experimental models of epilepsy in rats.
Epilepsy & behavior : E&B.
2011 Aug; 21(4):356-63. doi:
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2011 Aug; 25(8):1030-42. doi:
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Biochimica et biophysica acta.
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Journal of Ayurveda and integrative medicine.
2011 Jul; 2(3):129-36. doi:
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Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2011 Jun; 9(6):611-8. doi:
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Epilepsy research.
2011 Jun; 95(1-2):70-81. doi:
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Journal of neuroinflammation.
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Journal of ethnopharmacology.
2011 May; 135(2):434-9. doi:
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Seizure.
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Journal of medicinal food.
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Epilepsy & behavior : E&B.
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Acta poloniae pharmaceutica.
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Fitoterapia.
2011 Mar; 82(2):255-9. doi:
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Pharmaceutical biology.
2011 Feb; 49(2):194-9. doi:
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Journal of pharmaceutical and biomedical analysis.
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 Jan; 18(2-3):186-8. doi:
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Journal of ethnopharmacology.
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Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):403591. doi:
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Journal of advanced pharmaceutical technology & research.
2011 Jan; 2(1):3-8. doi:
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Acta poloniae pharmaceutica.
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Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences.
2011; 19(4):301-5. doi:
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Life sciences.
2010 Nov; 87(19-22):620-7. doi:
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Brain research bulletin.
2010 Nov; 83(6):356-9. doi:
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Journal of ethnopharmacology.
2010 Oct; 131(3):544-9. doi:
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Journal of natural medicines.
2010 Oct; 64(4):436-41. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2010 Oct; 17(12):940-9. doi:
10.1016/j.phymed.2010.03.002. [PMID: 20382514] - Kashmira J Gohil, Jagruti A Patel, Anuradha K Gajjar. Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all.
Indian journal of pharmaceutical sciences.
2010 Sep; 72(5):546-56. doi:
10.4103/0250-474x.78519. [PMID: 21694984] - Emmanuel E Ilodigwe, Peter A Akah, Chukwuemeka S Nworu. Anticonvulsant activity of ethanol leaf extract of Spathodea campanulata P. Beauv (Bignoniaceae).
Journal of medicinal food.
2010 Aug; 13(4):827-33. doi:
10.1089/jmf.2009.0144. [PMID: 20553140] - Eduardo L G Moreira, Daniel Rial, Filipe S Duarte, Cristiane Ribeiro de Carvalho, Heros Horst, Moacir G Pizzolatti, Rui D S Prediger, Rosa Maria Ribeiro-do-Valle. Central nervous system activity of the proanthocyanidin-rich fraction obtained from Croton celtidifolius in rats.
The Journal of pharmacy and pharmacology.
2010 Aug; 62(8):1061-8. doi:
10.1111/j.2042-7158.2010.01124.x. [PMID: 20663041] - R Estrada-Reyes, M Martínez-Vázquez, A Gallegos-Solís, G Heinze, J Moreno. Depressant effects of Clinopodium mexicanum Benth. Govaerts (Lamiaceae) on the central nervous system.
Journal of ethnopharmacology.
2010 Jul; 130(1):1-8. doi:
10.1016/j.jep.2010.03.012. [PMID: 20362043] - A Kumar, S Lingadurai, A Jain, N R Barman. Erythrina variegata Linn: A review on morphology, phytochemistry, and pharmacological aspects.
Pharmacognosy reviews.
2010 Jul; 4(8):147-52. doi:
10.4103/0973-7847.70908. [PMID: 22228954] - V J Galani, B G Patel, N B Patel. Argyreia speciosa (Linn. f.) sweet: A comprehensive review.
Pharmacognosy reviews.
2010 Jul; 4(8):172-8. doi:
10.4103/0973-7847.70913. [PMID: 22228958] - Marwa M Safar, Dalaal M Abdallah, Nadia M Arafa, Mohamed T Abdel-Aziz. Magnesium supplementation enhances the anticonvulsant potential of valproate in pentylenetetrazol-treated rats.
Brain research.
2010 Jun; 1334(?):58-64. doi:
10.1016/j.brainres.2010.03.076. [PMID: 20353763] - Wei Xie, Yunhong Yu, Yunyan Zhao. [Effect of Chaihu Shugan Tang on excitability in different brain regions of pentylenetetrazole-kindled chronic epileptic rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2010 Jun; 35(12):1619-22. doi:
10.4268/cjcmm20101225. [PMID: 20815220] - Ramya S Rao, Bikash Medhi, Krishan Lal Khanduja, Promila Pandhi. Correlation of seizures and biochemical parameters of oxidative stress in experimentally induced inflammatory rat models.
Fundamental & clinical pharmacology.
2010 Jun; 24(3):325-31. doi:
10.1111/j.1472-8206.2009.00773.x. [PMID: 20584211] - Mikael E Pedersen, Roger A Baldwin, Jerome Niquet, Gary I Stafford, Johannes van Staden, Claude G Wasterlain, Anna K Jäger. Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats.
Phytotherapy research : PTR.
2010 Jun; 24(6):924-7. doi:
10.1002/ptr.3016. [PMID: 19953526] - Joseph A Nicolazzo, Jessica A Steuten, Susan A Charman, Nerida Taylor, Philip J Davies, Steven Petrou. Brain uptake of diazepam and phenytoin in a genetic animal model of absence epilepsy.
Clinical and experimental pharmacology & physiology.
2010 May; 37(5-6):647-9. doi:
10.1111/j.1440-1681.2010.05362.x. [PMID: 20082623] - Tarun Arora, Ashish K Mehta, Krishna K Sharma, Pramod K Mediratta, Basu D Banerjee, Gobind R Garg, Amit K Sharma. Effect of carbamazepine and lamotrigine on cognitive function and oxidative stress in brain during chemical epileptogenesis in rats.
Basic & clinical pharmacology & toxicology.
2010 May; 106(5):372-7. doi:
10.1111/j.1742-7843.2009.00499.x. [PMID: 20002063] - Marjan Nassiri-Asl, Seyed-Reza Mortazavi, Fatemeh Samiee-Rad, Amir-Abdollah Zangivand, Freshteh Safdari, Sepideh Saroukhani, Esmail Abbasi. The effects of rutin on the development of pentylenetetrazole kindling and memory retrieval in rats.
Epilepsy & behavior : E&B.
2010 May; 18(1-2):50-3. doi:
10.1016/j.yebeh.2010.03.005. [PMID: 20452834] - Mahaveer Golechha, Jagriti Bhatia, Dharamvir Singh Arya. Hydroalcoholic extract of Emblica officinalis Gaertn. affords protection against PTZ-induced seizures, oxidative stress and cognitive impairment in rats.
Indian journal of experimental biology.
2010 May; 48(5):474-8. doi:
". [PMID: 20795364] - R Jayaraman, K T Manisenthil, T Anitha, Vishal D Joshi, Narahari N Palei, Kalpesh Gajera, Krupali Ladani. Influence of etoricoxib on anticonvulsant activity of phenytoin and diazepam in experimental seizure models in mice.
The Journal of pharmacy and pharmacology.
2010 May; 62(5):610-4. doi:
10.1211/jpp.62.05.0008. [PMID: 20609063] - Xinyue Jing, Xiang Liu, Tao Wen, Shanshan Xie, Dan Yao, Xiaodong Liu, Guangji Wang, Lin Xie. Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats.
British journal of pharmacology.
2010 Apr; 159(7):1511-22. doi:
10.1111/j.1476-5381.2009.00634.x. [PMID: 20233212] - Varsha J Galani, Bharatkumar G Patel. Effect of hydroalcoholic extract of Sphaeranthus indicus against experimentally induced anxiety, depression and convulsions in rodents.
International journal of Ayurveda research.
2010 Apr; 1(2):87-92. doi:
10.4103/0974-7788.64412. [PMID: 20814521] - Chandrakant Katiyar, Abhishek Kumar, S K Bhattacharya, R S Singh. Ayurvedic processed seeds of nux-vomica: neuropharmacological and chemical evaluation.
Fitoterapia.
2010 Apr; 81(3):190-5. doi:
10.1016/j.fitote.2009.08.023. [PMID: 19699784] - Gopalreddygari Visweswari, Kanchi Siva Prasad, Pandanaboina Sahitya Chetan, Valluru Lokanatha, Wudayagiri Rajendra. Evaluation of the anticonvulsant effect of Centella asiatica (gotu kola) in pentylenetetrazol-induced seizures with respect to cholinergic neurotransmission.
Epilepsy & behavior : E&B.
2010 Mar; 17(3):332-5. doi:
10.1016/j.yebeh.2010.01.002. [PMID: 20144879] - Katarzyna Socała, Dorota Nieoczym, Chris Rundfeldt, Piotr Wlaź. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models.
Pharmacological reports : PR.
2010 Mar; 62(2):392-7. doi:
10.1016/s1734-1140(10)70279-6. [PMID: 20508295] - Seyyed Majid Bagheri, Amirhossein Sahebkar, Ahmad Reza Gohari, Soodabeh Saeidnia, Maryam Malmir, Mehrdad Iranshahi. Evaluation of cytotoxicity and anticonvulsant activity of some Iranian medicinal Ferula species.
Pharmaceutical biology.
2010 Mar; 48(3):242-6. doi:
10.3109/13880200903081796. [PMID: 20645807] - Ameer Y Taha, Melanie A Jeffrey, Nadeen M Y Taha, Saimir Bala, W M Burnham. Acute administration of docosahexaenoic acid increases resistance to pentylenetetrazol-induced seizures in rats.
Epilepsy & behavior : E&B.
2010 Mar; 17(3):336-43. doi:
10.1016/j.yebeh.2010.01.001. [PMID: 20153982] - Nicholas A Jones, Andrew J Hill, Imogen Smith, Sarah A Bevan, Claire M Williams, Benjamin J Whalley, Gary J Stephens. Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.
The Journal of pharmacology and experimental therapeutics.
2010 Feb; 332(2):569-77. doi:
10.1124/jpet.109.159145. [PMID: 19906779] - Saeideh Momtaz, Namrita Lall, Ahmed Hussein, Seyed Nasser Ostad, Mohammad Abdollahi. Investigation of the possible biological activities of a poisonous South African plant; Hyaenanche globosa (Euphorbiaceae).
Pharmacognosy magazine.
2010 Jan; 6(21):34-41. doi:
10.4103/0973-1296.59964. [PMID: 20548934] - Jalsrai Aldarmaa, Zhongbo Liu, Jiangang Long, Xiaoyan Mo, Jiangang Ma, Jiankang Liu. Anti-convulsant effect and mechanism of Astragalus mongholicus extract in vitro and in vivo: protection against oxidative damage and mitochondrial dysfunction.
Neurochemical research.
2010 Jan; 35(1):33-41. doi:
10.1007/s11064-009-0027-4. [PMID: 19578991] - Mohammad Yasir, Sattwik Das, M D Kharya. The phytochemical and pharmacological profile of Persea americana Mill.
Pharmacognosy reviews.
2010 Jan; 4(7):77-84. doi:
10.4103/0973-7847.65332. [PMID: 22228945] - Maria Izabel Gomes Silva, Maria Angélica Gomes Silva, Manuel Rufino de Aquino Neto, Brinell Arcanjo Moura, Helenira Lourenço de Sousa, Everton Paulo Homem de Lavor, Patrícia Freire de Vasconcelos, Danielle Silveira Macêdo, Damião Pergentino de Sousa, Silvânia Maria Mendes Vasconcelos, Francisca Cléa Florenço de Sousa. Effects of isopulegol on pentylenetetrazol-induced convulsions in mice: possible involvement of GABAergic system and antioxidant activity.
Fitoterapia.
2009 Dec; 80(8):506-13. doi:
10.1016/j.fitote.2009.06.011. [PMID: 19559770] - Manoj Goyal, B P Nagori, D Sasmal. Sedative and anticonvulsant effects of an alcoholic extract of Capparis decidua.
Journal of natural medicines.
2009 Oct; 63(4):375-9. doi:
10.1007/s11418-009-0339-3. [PMID: 19452247] - Bikash Medhi, Ajay Prakash, Pramod K Avti, Amitava Chakrabarti, Krishan L Khanduja. Intestinal inflammation and seizure susceptibility: understanding the role of tumour necrosis factor-alpha in a rat model.
The Journal of pharmacy and pharmacology.
2009 Oct; 61(10):1359-64. doi:
10.1211/jpp/61.10.0013. [PMID: 19814869] - Jude E Okokon, Paul A Nwafor. Antiulcer and anticonvulsant activity of Croton zambesicus.
Pakistan journal of pharmaceutical sciences.
2009 Oct; 22(4):384-90. doi:
. [PMID: 19783516] - Jennifer François, Arielle Ferrandon, Estelle Koning, Marie-José Angst, Guy Sandner, Astrid Nehlig. Selective reorganization of GABAergic transmission in neonatal ventral hippocampal-lesioned rats.
The international journal of neuropsychopharmacology.
2009 Sep; 12(8):1097-110. doi:
10.1017/s1461145709009985. [PMID: 19267957] - K K Akula, A Dhir, S K Kulkarni. Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice.
Methods and findings in experimental and clinical pharmacology.
2009 Sep; 31(7):423-32. doi:
10.1358/mf.2009.31.7.1393610. [PMID: 19907717] - E Ngo Bum, G S Taiwe, F C O Moto, G T Ngoupaye, G C N Nkantchoua, M M Pelanken, S V Rakotonirina, A Rakotonirina. Anticonvulsant, anxiolytic, and sedative properties of the roots of Nauclea latifolia Smith in mice.
Epilepsy & behavior : E&B.
2009 Aug; 15(4):434-40. doi:
10.1016/j.yebeh.2009.05.014. [PMID: 19560975] - F P Ching, E K I Omogbai, I O Otokiti. Aqueous stem bark extract of Stereospermum kunthianum (Cham, Sandrine Petit) protects against generalized seizures in pentylenetetrazole and electro-convulsive models in rodents.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2009 Jul; 6(4):544-8. doi:
10.4314/ajtcam.v6i4.57197. [PMID: 20606775] - Silvânia Maria Mendes Vasconcelos, Silvane R Lima, Paula Matias Soares, Ana Maria Sampaio Assreuy, Francisca Cléa Florenço de Sousa, Rodrigo de Freitas Guimarães Lobato, Germana Silva Vasconcelos, Tatiane Santi-Gadelha, Eduardo Henrique Salviano Bezerra, Benildo Sousa Cavada, Manoel Cláudio Azevedo Patrocínio. Central action of Araucaria angustifolia seed lectin in mice.
Epilepsy & behavior : E&B.
2009 Jul; 15(3):291-3. doi:
10.1016/j.yebeh.2009.05.002. [PMID: 19446042] - Antônio C Neto, Joaquim C Netto, Paulo S Pereira, Ana M S Pereira, Sílvia H Taleb-Contini, Suzelei C França, Márcia O M Marques, René O Beleboni. The role of polar phytocomplexes on anticonvulsant effects of leaf extracts of Lippia alba (Mill.) N.E. Brown chemotypes.
The Journal of pharmacy and pharmacology.
2009 Jul; 61(7):933-9. doi:
10.1211/jpp/61.07.0013. [PMID: 19589236] - Taku Doi, Yuto Ueda, Keiko Nagatomo, L James Willmore. Role of glutamate and GABA transporters in development of pentylenetetrazol-kindling.
Neurochemical research.
2009 Jul; 34(7):1324-31. doi:
10.1007/s11064-009-9912-0. [PMID: 19169815]