4-Hydroperoxy-2-nonenal (BioDeep_00000018218)

   

human metabolite


代谢物信息卡片


4-Hydroxyperoxy-trans-2-nonenal

化学式: C9H16O3 (172.10993860000002)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC(C=CC=O)OO
InChI: InChI=1S/C9H16O3/c1-2-3-4-6-9(12-11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3/b7-5+

描述信息

This compound belongs to the family of Medium-chain Aldehydes. These are An aldehyde with a chain length containing between 6 and 12 carbon atoms.

同义名列表

4 个代谢物同义名

4-Hydroxyperoxy-trans-2-nonenal; (2E)-4-hydroperoxynon-2-enal; 4-HYDROPEROXYNON-2-ENAL; 4-Hydroperoxy-2-nonenal



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sten Ten Klooster, Karin Schroën, Claire Berton-Carabin. Lipid oxidation products in model food emulsions: do they stay in or leave droplets, that's the question. Food chemistry. 2023 Mar; 405(Pt B):134992. doi: 10.1016/j.foodchem.2022.134992. [PMID: 36436238]
  • Ryo Takahashi, Takaaki Goto, Tomoyuki Oe, Seon Hwa Lee. Angiotensin II modification by decomposition products of linoleic acid-derived lipid hydroperoxide. Chemico-biological interactions. 2015 Sep; 239(?):87-99. doi: 10.1016/j.cbi.2015.06.029. [PMID: 26111765]
  • Sushabhan Sadhukhan, Yong Han, Zhicheng Jin, Gregory P Tochtrop, Guo-Fang Zhang. Glutathionylated 4-hydroxy-2-(E)-alkenal enantiomers in rat organs and their contributions toward the disposal of 4-hydroxy-2-(E)-nonenal in rat liver. Free radical biology & medicine. 2014 May; 70(?):78-85. doi: 10.1016/j.freeradbiomed.2014.02.008. [PMID: 24556413]
  • F Cervellati, C Cervellati, A Romani, E Cremonini, C Sticozzi, G Belmonte, F Pessina, G Valacchi. Hypoxia induces cell damage via oxidative stress in retinal epithelial cells. Free radical research. 2014 Mar; 48(3):303-12. doi: 10.3109/10715762.2013.867484. [PMID: 24286355]
  • Paiboon Jungsuwadee, Tianyong Zhao, Elzbieta I Stolarczyk, Christian M Paumi, D Allan Butterfield, Daret K St Clair, Mary Vore. The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal. Pharmacogenetics and genomics. 2012 Apr; 22(4):273-84. doi: 10.1097/fpc.0b013e328350e270. [PMID: 22293538]
  • Beata Janowska, Dagmara Kurpios-Piec, Paulina Prorok, Grzegorz Szparecki, Marek Komisarski, Paweł Kowalczyk, Celina Janion, Barbara Tudek. Role of damage-specific DNA polymerases in M13 phage mutagenesis induced by a major lipid peroxidation product trans-4-hydroxy-2-nonenal. Mutation research. 2012 Jan; 729(1-2):41-51. doi: 10.1016/j.mrfmmm.2011.09.006. [PMID: 22001238]
  • Hani A Al-Shobaili, Ahmad A Al Robaee, Abdullateef A Alzolibani, Zafar Rasheed. Antibodies against 4-hydroxy-2-nonenal modified epitopes recognized chromatin and its oxidized forms: role of chromatin, oxidized forms of chromatin and 4-hydroxy-2-nonenal modified epitopes in the etiopathogenesis of SLE. Disease markers. 2012; 33(1):19-34. doi: 10.3233/dma-2012-0900. [PMID: 22710866]
  • Yuuki Shimozu, Keita Hirano, Takahiro Shibata, Noriyuki Shibata, Koji Uchida. 4-Hydroperoxy-2-nonenal is not just an intermediate but a reactive molecule that covalently modifies proteins to generate unique intramolecular oxidation products. The Journal of biological chemistry. 2011 Aug; 286(33):29313-29324. doi: 10.1074/jbc.m111.255737. [PMID: 21690609]
  • Heather C Kuiper, Richard S Bruno, Maret G Traber, Jan F Stevens. Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans. Free radical biology & medicine. 2011 Apr; 50(7):848-53. doi: 10.1016/j.freeradbiomed.2011.01.004. [PMID: 21236333]
  • P Joseph, S P Suman, S Li, C M Beach, L Steinke, M Fontaine. Characterization of bison (Bison bison) myoglobin. Meat science. 2010 Jan; 84(1):71-8. doi: 10.1016/j.meatsci.2009.08.014. [PMID: 20374756]
  • Jon Zárate, Encarnación Goicoechea, Jesús Pascual, Enrique Echevarría, Mariá D Guillén. A study of the toxic effect of oxidized sunflower oil containing 4-hydroperoxy-2-nonenal and 4-hydroxy-2-nonenal on cortical TrkA receptor expression in rats. Nutritional neuroscience. 2009 Dec; 12(6):249-59. doi: 10.1179/147683009x423391. [PMID: 19925718]