(Z)-6,7-Dichloro-3-(hydroxyimino)indolin-2-one (BioDeep_00000181812)
human metabolite blood metabolite
代谢物信息卡片
化学式: C8H4Cl2N2O2 (229.96498240000003)
中文名称: NS309
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C2=C1C(=C(N2)O)N=O)Cl)Cl
InChI: InChI=1S/C8H4Cl2N2O2/c9-4-2-1-3-6(5(4)10)11-8(13)7(3)12-14/h1-2,11,13H
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Erik J Behringer, Steven S Segal. Membrane potential governs calcium influx into microvascular endothelium: integral role for muscarinic receptor activation.
The Journal of physiology.
2015 Oct; 593(20):4531-48. doi:
10.1113/jp271102. [PMID: 26260126] - T T Troelsen, A Granfeldt, N Secher, E K Tønnesen, U Simonsen. Impaired NO-mediated vasodilatation in rat coronary arteries after asphyxial cardiac arrest.
Acta anaesthesiologica Scandinavica.
2015 May; 59(5):654-67. doi:
10.1111/aas.12482. [PMID: 25881833] - Serge Simonet, Marc Isabelle, Mélanie Bousquenaud, Nicolas Clavreul, Michel Félétou, Christine Vayssettes-Courchay, Tony J Verbeuren. KCa 3.1 channels maintain endothelium-dependent vasodilatation in isolated perfused kidneys of spontaneously hypertensive rats after chronic inhibition of NOS.
British journal of pharmacology.
2012 Oct; 167(4):854-67. doi:
10.1111/j.1476-5381.2012.02062.x. [PMID: 22646737] - Rachel V Seear, Virgilio L Lew. IKCa agonist (NS309)-elicited all-or-none dehydration response of human red blood cells is cell-age dependent.
Cell calcium.
2011 Nov; 50(5):444-8. doi:
10.1016/j.ceca.2011.07.005. [PMID: 21937109] - A M Dolga, N Terpolilli, F Kepura, I M Nijholt, H-G Knaus, B D'Orsi, J H M Prehn, U L M Eisel, T Plant, N Plesnila, C Culmsee. KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia.
Cell death & disease.
2011 Apr; 2(?):e147. doi:
10.1038/cddis.2011.30. [PMID: 21509037] - Huifang Ji, Charlotte Hougaard, Kjartan Frisch Herrik, Dorte Strøbaek, Palle Christophersen, Paul D Shepard. Tuning the excitability of midbrain dopamine neurons by modulating the Ca2+ sensitivity of SK channels.
The European journal of neuroscience.
2009 May; 29(9):1883-95. doi:
10.1111/j.1460-9568.2009.06735.x. [PMID: 19473240] - Susanne Jørgensen, Tina H Johansen, Tino Dyhring. Fluorescence-based Tl(+)-influx assays as a novel approach for characterization of small-conductance Ca(2+)-activated K (+) channel modulators.
Methods in molecular biology (Clifton, N.J.).
2008; 491(?):257-66. doi:
10.1007/978-1-59745-526-8_20. [PMID: 18998099]