Noxytiolin (BioDeep_00000181799)
human metabolite blood metabolite
代谢物信息卡片
化学式: C3H8N2OS (120.03573180000001)
中文名称: 诺昔硫脲
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CNC(=S)NCO
InChI: InChI=1S/C3H8N2OS/c1-4-3(7)5-2-6/h6H,2H2,1H3,(H2,4,5,7)
描述信息
B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05C - Irrigating solutions > B05CA - Antiinfectives
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D000890 - Anti-Infective Agents
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:134756
- PubChem: 5251503
- PubChem: 519136
- HMDB: HMDB0255760
- DrugBank: DB13838
- ChEMBL: CHEMBL2106441
- Wikipedia: Noxytiolin
- MeSH: Noxythiolin
- chemspider: 4418329
- CAS: 15599-39-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- J I Blenkharn. In-vitro antibacterial activity of noxythiolin and taurolidine.
The Journal of pharmacy and pharmacology.
1990 Aug; 42(8):589-90. doi:
10.1111/j.2042-7158.1990.tb07066.x. [PMID: 1981591] - A C Buck. The use of noxythiolin (Noxyflex 'S') as an antiseptic irrigant in upper urinary tract drainage following percutaneous nephrolithotomy.
British journal of urology.
1988 Oct; 62(4):306-10. doi:
10.1111/j.1464-410x.1988.tb04353.x. [PMID: 3142634] - M A Jones, A Hasan. Controlled trial of intravesical noxythiolin in the prevention of infection following outflow tract surgery.
British journal of urology.
1988 Oct; 62(4):311-4. doi:
10.1111/j.1464-410x.1988.tb04354.x. [PMID: 3142635] - J I Blenkharn. Sustained anti-adherence activity of taurolidine (Taurolin) and noxythiolin (Noxyflex S) solutions.
The Journal of pharmacy and pharmacology.
1988 Jul; 40(7):509-11. doi:
10.1111/j.2042-7158.1988.tb05288.x. [PMID: 2904994] - W N Cottrell, R W Fitzpatrick. Determination of in vivo concentration-time profiles of chlorhexidine and noxythiolin bladder irrigations.
Journal of clinical and hospital pharmacy.
1986 Oct; 11(5):335-42. doi:
10.1111/j.1365-2710.1986.tb00861.x. [PMID: 3097078] - S P Gorman, D F McCafferty, A D Woolfson, L Anderson. Decrease in adherence of bacteria and yeasts to human mucosal epithelial cells by noxythiolin in vitro.
The Journal of applied bacteriology.
1986 Apr; 60(4):311-7. doi:
10.1111/j.1365-2672.1986.tb01738.x. [PMID: 3087930] - D Debruyne, M A Moulin, H Bricard, M C Bigot. Liquid chromatographic determination of noxytiolin and 1-methyl-2-thiourea in serum: application to pharmacokinetic studies in rabbits and humans.
Journal of pharmaceutical sciences.
1985 Feb; 74(2):224-6. doi:
10.1002/jps.2600740227. [PMID: 3921689] - A R Jones, P M Mashford. The fate of N-methyl-N'-(hydroxymethyl)thiourea in the rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1983 Feb; 13(2):73-9. doi:
10.3109/00498258309052239. [PMID: 6410593] - F L Rosenfeldt, J R Glover, D Marossy. Systemic absorption of noxythiolin from the pleural cavity in man and in the rabbit.
Thorax.
1981 Apr; 36(4):278-81. doi:
10.1136/thx.36.4.278. [PMID: 6792736] - D J Stickler, S Plant, N H Bunni, J C Chawla. Some observations on the activity of three antiseptics used as bladder irrigants in the treatment of urinary tract infection in patients with indwelling catheters.
Paraplegia.
1981; 19(6):325-33. doi:
10.1038/sc.1981.63. [PMID: 6796928]