Nitroxinil (BioDeep_00000181728)
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
4-hydroxy-3-iodo-5-nitrobenzonitrile
化学式: C7H3IN2O3 (289.9188438)
中文名称: 硝碘酚腈
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=C(C=C(C(=C1[N+](=O)[O-])O)I)C#N
InChI: InChI=1S/C7H3IN2O3/c8-5-1-4(3-9)2-6(7(5)11)10(12)13/h1-2,11H
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
同义名列表
6 个代谢物同义名
4-hydroxy-3-iodo-5-nitrobenzonitrile; Nitroxynil; Nitroxinil; Deldrax; Trodax; Nitroxinil
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sally Ashraf, F Belal, M M Salim. Spectrofluorometric determination of residual amounts of nitroxynil in food samples.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Jun; 274(?):120993. doi:
10.1016/j.saa.2022.120993. [PMID: 35245802] - Bruno Batista Bortoluzzi, Andréia Buzatti, Amanda Chaaban, Izanara Cristine Pritsch, Alan Dos Anjos, Roger Raup Cipriano, Cícero Deschamps, Marcelo Beltrão Molento. Mentha villosa Hubs., M. x piperita and their bioactives against gastrointestinal nematodes of ruminants and the potential as drug enhancers.
Veterinary parasitology.
2021 Jan; 289(?):109317. doi:
10.1016/j.vetpar.2020.109317. [PMID: 33246235] - Guanqiong Na, Xiaofei Hu, Jifei Yang, Yaning Sun, Sharon Kwee, Liang Tang, Guangxu Xing, Yunrui Xing, Gaiping Zhang. A rapid colloidal gold-based immunochromatographic strip assay for monitoring nitroxynil in milk.
Journal of the science of food and agriculture.
2020 Mar; 100(5):1860-1866. doi:
10.1002/jsfa.10074. [PMID: 31602650] - Javiera Romero, Carmen Villaguala, Fernando Quiroz, Carlos Landaeta-Aqueveque, Guillermo Alfaro, Rubén Pérez. Flukicide efficacy against Fasciola hepatica of Triclabendazole and Nitroxynil in cattle of the central valley of Chile.
Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria.
2019 Jan; 28(1):164-167. doi:
10.1590/s1984-296120180089. [PMID: 30892461] - R E B Hanna, C McMahon, S Ellison, H W Edgar, P-E Kajugu, A Gordon, D Irwin, J P Barley, F E Malone, G P Brennan, I Fairweather. Fasciola hepatica: a comparative survey of adult fluke resistance to triclabendazole, nitroxynil and closantel on selected upland and lowland sheep farms in Northern Ireland using faecal egg counting, coproantigen ELISA testing and fluke histology.
Veterinary parasitology.
2015 Jan; 207(1-2):34-43. doi:
10.1016/j.vetpar.2014.11.016. [PMID: 25529143] - I M Traynor, C S Thompson, L Armstrong, M Whelan, M Danaher, D G Kennedy, S R H Crooks. Determination of nitroxynil residues in tissues and bovine milk by immunobiosensor.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2013; 30(6):1115-22. doi:
10.1080/19440049.2013.781274. [PMID: 23566247] - Maria Martínez-Valladares, Maria del Rosario Famularo, Nelida Fernández-Pato, Luciano Castañón-Ordóñez, Coral Cordero-Pérez, Francisco Antonio Rojo-Vázquez. Efficacy of nitroxynil against Fasciola hepatica resistant to triclabendazole in a naturally infected sheep flock.
Parasitology research.
2010 Oct; 107(5):1205-11. doi:
10.1007/s00436-010-1989-5. [PMID: 20680341] - L Moreno, L Ceballos, A Lifschitz, M Bistoletti, L Alvarez, C Lanusse. Combined subcutaneous administration of ivermectin and nitroxynil in sheep: age/body weight related changes to the kinetic disposition of both compounds.
Research in veterinary science.
2010 Apr; 88(2):315-20. doi:
10.1016/j.rvsc.2009.10.002. [PMID: 19892381] - G Baziard-Mouysset, M Alvinerie, P Galtier, M Ane-Margail, R Floch, M Payard. [Study of plasma and hepatic hydrolysis of nitroxinil derivatives].
Annales pharmaceutiques francaises.
1996; 54(5):223-7. doi:
NULL. [PMID: 8953797] - R Maffei Facino, M Carini, G Aldini, R Ceserani, I Casciarri, E Cavalletti, L Verderio. Efficacy of glutathione for treatment of fascioliasis. An investigation in the experimentally infested rat.
Arzneimittel-Forschung.
1993 Apr; 43(4):455-60. doi:
. [PMID: 8494576] - D Levieux, A Levieux, C Mage, J P Garel. Immunological detection of chemotherapeutic success in bovine fasciolosis using the specific antigen f2.
Veterinary parasitology.
1992 Dec; 45(1-2):81-8. doi:
10.1016/0304-4017(92)90029-9. [PMID: 1485423] - F A Echevarria, M B Correa, R D Wehrle, I F Correa. Experiments on anthelmintic control of Fasciola hepatica in Brazil.
Veterinary parasitology.
1992 Jul; 43(3-4):211-22. doi:
10.1016/0304-4017(92)90162-3. [PMID: 1413453] - M Alvinerie, R Floc'h, P Galtier. Plasma protein binding of nitroxynil in several species.
Journal of veterinary pharmacology and therapeutics.
1991 Jun; 14(2):170-3. doi:
10.1111/j.1365-2885.1991.tb00819.x. [PMID: 1920604] - P C Jeannin, K Bairden, G Gettinby, M Murray, G M Urquhart. Efficacy of nitroxynil against ivermectin, benzimidazole and salicylanilide resistant H contortus.
The Veterinary record.
1990 Jun; 126(25):624-5. doi:
NULL. [PMID: 2378049] - W J Blanchflower, D G Kennedy. Determination of nitroxynil residues in tissues using high-performance liquid chromatography-thermospray mass spectrometry.
The Analyst.
1989 Sep; 114(9):1013-5. doi:
10.1039/an9891401013. [PMID: 2610364] - P C Jeannin. Efficacy of nitroxynil against a benzimidazole-resistant strain of Haemonchus contortus in sheep.
The Veterinary record.
1989 Jun; 124(25):662-3. doi:
10.1136/vr.124.25.662. [PMID: 2763432] - L Rubilar, A Cabreira, L Giacaman. Treatment of Fasciola hepatica infection in horses with triclabendazole.
The Veterinary record.
1988 Sep; 123(12):320-1. doi:
10.1136/vr.123.12.320. [PMID: 3195012] - D Rapic, N Dzakula, D Sakar, R J Richards. Comparative efficacy of triclabendazole, nitroxynil and rafoxanide against immature and mature Fasciola hepatica in naturally infected cattle.
The Veterinary record.
1988 Jan; 122(3):59-62. doi:
10.1136/vr.122.3.59. [PMID: 3354156] - D C Jenkins, P Topley, E B Rapson. Fasciola hepatica in vitro: increased susceptibility to fasciolicides in a defined serum-free medium.
Parasitology.
1987 Aug; 95 ( Pt 1)(?):165-71. doi:
10.1017/s0031182000057644. [PMID: 3670897] - I W Caple, M R Jainudeen, T D Buick, C Y Song. Some clinico-pathologic findings in elephants (Elephas maximus) infected with Fasciola jacksoni.
Journal of wildlife diseases.
1978 Jan; 14(1):110-5. doi:
10.7589/0090-3558-14.1.110. [PMID: 633508] - J Vyhnálek, J Kocman, J Skaloud. [Effectiveness of Nilzan and Dovenix in the treatment of fascioliasis in cattle and sheep].
Veterinarni medicina.
1976 Jul; 21(7):427-33. doi:
. [PMID: 827048] - B M Stammers. The effects of nitroxynil on the survival, growth and morphology of Fasciola hepatica in sheep.
Research in veterinary science.
1976 Mar; 20(2):174-9. doi:
10.1016/s0034-5288(18)33452-0. [PMID: 1265355] - J D Whitehead. Observations on the repeated treatment for fascioliasis of stock on a farm in south-west England.
The Veterinary record.
1976 Jan; 98(1):5-9. doi:
10.1136/vr.98.1.5. [PMID: 943881] - S B Kendall, J W Parfitt. Chemotherapy of infection with Fasciola hepatica in cattle.
The Veterinary record.
1975 Jul; 97(1):9-12. doi:
10.1136/vr.97.1.9. [PMID: 1146190]