Niranthin (BioDeep_00000181688)

Main id: BioDeep_00000277293

 

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


6-{3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl}-4-methoxy-2H-1,3-benzodioxole

化学式: C24H32O7 (432.2148)
中文名称: rac-珠子草素-d4
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COCC(CC1=CC(=C(C=C1)OC)OC)C(CC2=CC3=C(C(=C2)OC)OCO3)COC
InChI: InChI=1S/C24H32O7/c1-25-13-18(8-16-6-7-20(27-3)21(10-16)28-4)19(14-26-2)9-17-11-22(29-5)24-23(12-17)30-15-31-24/h6-7,10-12,18-19H,8-9,13-15H2,1-5H3

描述信息

同义名列表

2 个代谢物同义名

6-{3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl}-4-methoxy-2H-1,3-benzodioxole; Niranthin



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jinal Patel, Padamnabhi Shanker Nagar, Kalpana Pal, Raghuraj Singh, Tushar Dhanani, Vyomesh Patel, Sharad Srivastava, Satyanshu Kumar. Comparative Profiling of Four Lignans (Phyllanthin, Hypophyllanthin, Nirtetralin, and Niranthin) in Nine Phyllanthus Species from India Using a Validated Reversed Phase HPLC-PDA Detection Method. Journal of AOAC International. 2021 May; 104(2):485-497. doi: 10.1093/jaoacint/qsaa133. [PMID: 33259591]
  • Sheng Liu, Wanxing Wei, Kaichuang Shi, Xun Cao, Min Zhou, Zhiping Liu. In vitro and in vivo anti-hepatitis B virus activities of the lignan niranthin isolated from Phyllanthus niruri L. Journal of ethnopharmacology. 2014 Sep; 155(2):1061-7. doi: 10.1016/j.jep.2014.05.064. [PMID: 25009077]
  • Graziella Rigueira Molska, Giuseppina Negri, Lyvia Izaura Gomes Paula-Freire, Leandro Pires Araujo, Daniele Oliveira Köhn, Alexandre Salgado Basso, Elisaldo Araújo Carlini. Phyllanthus amarus does not affect hypernociception in experimental autoimmune encephalomyelitis. Planta medica. 2014 Mar; 80(4):277-82. doi: 10.1055/s-0033-1360400. [PMID: 24610345]
  • Sayan Chowdhury, Tulika Mukherjee, Rupkatha Mukhopadhyay, Budhaditya Mukherjee, Souvik Sengupta, Sharmila Chattopadhyay, Parasuraman Jaisankar, Syamal Roy, Hemanta K Majumder. The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice. EMBO molecular medicine. 2012 Oct; 4(10):1126-43. doi: 10.1002/emmm.201201316. [PMID: 23027614]
  • Cândida A L Kassuya, Aline Silvestre, Octávio Menezes-de-Lima, Denise Mollica Marotta, Vera Lúcia G Rehder, João B Calixto. Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor. European journal of pharmacology. 2006 Sep; 546(1-3):182-8. doi: 10.1016/j.ejphar.2006.07.025. [PMID: 16925995]
  • Ray-Ling Huang, Yu-Ling Huang, Jun-Chih Ou, Chien-Chih Chen, Feng-Lin Hsu, Chungming Chang. Screening of 25 compounds isolated from Phyllanthus species for anti-human hepatitis B virus in vitro. Phytotherapy research : PTR. 2003 May; 17(5):449-53. doi: 10.1002/ptr.1167. [PMID: 12748977]