Nile red (BioDeep_00000181674)
human metabolite blood metabolite
代谢物信息卡片
8-(diethylamino)-12H-10-oxa-5-azatetraphen-12-one
化学式: C20H18N2O2 (318.13682079999995)
中文名称: 尼罗丝
谱图信息:
最多检出来源 Homo sapiens(blood) 18.27%
分子结构信息
SMILES: CCN(CC)C1=CC2=C(C=C1)N=C1C(O2)=CC(=O)C2=CC=CC=C12
InChI: InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:52169
- PubChem: 65182
- HMDB: HMDB0255607
- ChEMBL: CHEMBL144472
- Wikipedia: Nile red
- chemspider: 58681
- CAS: 7385-67-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Francesco Martelli, Valentina Bernini, Erasmo Neviani, Vitor Vasconcelos, Ralph Urbatzka. Lactic acid fermented microalgae and cyanobacteria as a new source of lipid reducing compounds: assessment through zebrafish Nile red fat metabolism assay and untargeted metabolomics.
Food & function.
2024 May; 15(10):5554-5565. doi:
10.1039/d4fo00699b. [PMID: 38712867] - Benjamin Ouellet, Zacharie Morneau, Ahmad M Abdel-Mawgoud. Nile red-based lipid fluorometry protocol and its use for statistical optimization of lipids in oleaginous yeasts.
Applied microbiology and biotechnology.
2023 Dec; 107(23):7313-7330. doi:
10.1007/s00253-023-12786-9. [PMID: 37741936] - Simona Bisogno, Łukasz Gąsior, Grażyna E Ptak. Nile Red and BODIPY Staining of Lipid Droplets in Mouse Oocytes and Embryos.
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ACS chemical biology.
2015 Jun; 10(6):1435-42. doi:
10.1021/cb500922m. [PMID: 25710589] - Eugenia J Olguín, Omar S Castillo, Anilú Mendoza, Karla Tapia, Ricardo E González-Portela, Víctor J Hernández-Landa. Dual purpose system that treats anaerobic effluents from pig waste and produce Neochloris oleoabundans as lipid rich biomass.
New biotechnology.
2015 May; 32(3):387-95. doi:
10.1016/j.nbt.2014.12.004. [PMID: 25556121] - Pronab Kundu, Saptarshi Ghosh, Barnali Jana, Nitin Chattopadhyay. Binding interaction of differently charged fluorescent probes with egg yolk phosphatidylcholine and the effect of β-cyclodextrin on the lipid-probe complexes: a fluorometric investigation.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2015 May; 142(?):15-24. doi:
10.1016/j.saa.2015.01.038. [PMID: 25698439] - Iago Teles Dominguez Cabanelas, Mathijs van der Zwart, Dorinde M M Kleinegris, Maria J Barbosa, René H Wijffels. Rapid method to screen and sort lipid accumulating microalgae.
Bioresource technology.
2015 May; 184(?):47-52. doi:
10.1016/j.biortech.2014.10.057. [PMID: 25453436] - Ramkumar Iyer, Annette Ferrari, R Rijnbrand, Alice L Erwin. A fluorescent microplate assay quantifies bacterial efflux and demonstrates two distinct compound binding sites in AcrB.
Antimicrobial agents and chemotherapy.
2015 Apr; 59(4):2388-97. doi:
10.1128/aac.05112-14. [PMID: 25645845] - Hamid Rismani-Yazdi, Kristin H Hampel, Christopher D Lane, Ben A Kessler, Nicholas M White, Kenneth M Moats, F C Thomas Allnutt. High-productivity lipid production using mixed trophic state cultivation of Auxenochlorella (Chlorella) protothecoides.
Bioprocess and biosystems engineering.
2015 Apr; 38(4):639-50. doi:
10.1007/s00449-014-1303-5. [PMID: 25326061] - Soujanya Kuntam, László G Puskás, Ferhan Ayaydin. Characterization of a new class of blue-fluorescent lipid droplet markers for live-cell imaging in plants.
Plant cell reports.
2015 Apr; 34(4):655-65. doi:
10.1007/s00299-015-1738-4. [PMID: 25604989] - Sebastien Elis, Alice Desmarchais, Virginie Maillard, Svetlana Uzbekova, Philippe Monget, Joëlle Dupont. Cell proliferation and progesterone synthesis depend on lipid metabolism in bovine granulosa cells.
Theriogenology.
2015 Mar; 83(5):840-53. doi:
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Marine biotechnology (New York, N.Y.).
2015 Feb; 17(1):66-80. doi:
10.1007/s10126-014-9597-5. [PMID: 25189135] - Gahl Levy, Merav Cohen, Yaakov Nahmias. In Vitro Cell Culture Models of Hepatic Steatosis.
Methods in molecular biology (Clifton, N.J.).
2015; 1250(?):377-90. doi:
10.1007/978-1-4939-2074-7_29. [PMID: 26272159] - Mia Terashima, Elizabeth S Freeman, Robert E Jinkerson, Martin C Jonikas. A fluorescence-activated cell sorting-based strategy for rapid isolation of high-lipid Chlamydomonas mutants.
The Plant journal : for cell and molecular biology.
2015 Jan; 81(1):147-59. doi:
10.1111/tpj.12682. [PMID: 25267488] - Takashi Kawase, Shigeo S Sugano, Tomoo Shimada, Ikuko Hara-Nishimura. A direction-selective local-thresholding method, DSLT, in combination with a dye-based method for automated three-dimensional segmentation of cells and airspaces in developing leaves.
The Plant journal : for cell and molecular biology.
2015 Jan; 81(2):357-66. doi:
10.1111/tpj.12738. [PMID: 25440085] - Alexandra Arranja, André P Schroder, Marc Schmutz, Gilles Waton, François Schosseler, Eduardo Mendes. Cytotoxicity and internalization of Pluronic micelles stabilized by core cross-linking.
Journal of controlled release : official journal of the Controlled Release Society.
2014 Dec; 196(?):87-95. doi:
10.1016/j.jconrel.2014.10.001. [PMID: 25307996] - Shu-Lin Liu, Ren Sheng, Matthew J O'Connor, Yang Cui, Youngdae Yoon, Svetlana Kurilova, Daesung Lee, Wonhwa Cho. Simultaneous in situ quantification of two cellular lipid pools using orthogonal fluorescent sensors.
Angewandte Chemie (International ed. in English).
2014 Dec; 53(52):14387-91. doi:
10.1002/anie.201408153. [PMID: 25345859] - Mohamed Dawoud, Fahima M Hashem. Comparative study on the suitability of two techniques for measuring the transfer of lipophilic drug models from lipid nanoparticles to lipophilic acceptors.
AAPS PharmSciTech.
2014 Dec; 15(6):1551-61. doi:
10.1208/s12249-014-0179-7. [PMID: 25128298] - Yuning Gao, Guanqun Chen, Randall J Weselake. A rapid nile red fluorescence-based method for triacylglycerol content in microspore-derived cell suspension cultures of Brassica napus.
Lipids.
2014 Nov; 49(11):1161-8. doi:
10.1007/s11745-014-3952-1. [PMID: 25223985] - Roopali Saxena, Sandeep Shrivastava, Sourav Haldar, Andrey S Klymchenko, Amitabha Chattopadhyay. Location, dynamics and solvent relaxation of a Nile Red-based phase-sensitive fluorescent membrane probe.
Chemistry and physics of lipids.
2014 Oct; 183(?):1-8. doi:
10.1016/j.chemphyslip.2014.04.007. [PMID: 24802972] - David J Guckenberger, Erwin Berthier, Edmond W K Young, David J Beebe. Fluorescence-based assessment of plasma-induced hydrophilicity in microfluidic devices via Nile Red adsorption and depletion.
Analytical chemistry.
2014 Aug; 86(15):7258-63. doi:
10.1021/ac501259n. [PMID: 25032783] - Mónica L López, Carlos O Kieling, Carolina Uribe Cruz, Alessandro Osvaldt, Gustavo Ochs de Muñoz, Luise Meurer, Lucia Silla, Ursula Matte. Platelet increases survival in a model of 90\% hepatectomy in rats.
Liver international : official journal of the International Association for the Study of the Liver.
2014 Aug; 34(7):1049-56. doi:
10.1111/liv.12326. [PMID: 24119092] - Natarajan Velmurugan, Yesupatham Sathishkumar, Sung Sun Yim, Yang Soo Lee, Min S Park, Ji Won Yang, Ki Jun Jeong. Study of cellular development and intracellular lipid bodies accumulation in the thraustochytrid Aurantiochytrium sp. KRS101.
Bioresource technology.
2014 Jun; 161(?):149-54. doi:
10.1016/j.biortech.2014.03.017. [PMID: 24704836] - Chee Loong Teo, Madiha Atta, Attaullah Bukhari, Mohamad Taisir, Afendi M Yusuf, Ani Idris. Enhancing growth and lipid production of marine microalgae for biodiesel production via the use of different LED wavelengths.
Bioresource technology.
2014 Jun; 162(?):38-44. doi:
10.1016/j.biortech.2014.03.113. [PMID: 24736210] - Zachary J Storms, Elliot Cameron, Hector de la Hoz Siegler, William C McCaffrey. A simple and rapid protocol for measuring neutral lipids in algal cells using fluorescence.
Journal of visualized experiments : JoVE.
2014 May; ?(87):. doi:
10.3791/51441. [PMID: 24961928] - Lital Davidi, Eyal Shimoni, Inna Khozin-Goldberg, Ada Zamir, Uri Pick. Origin of β-carotene-rich plastoglobuli in Dunaliella bardawil.
Plant physiology.
2014 Apr; 164(4):2139-56. doi:
10.1104/pp.113.235119. [PMID: 24567188] - Efthymia Prifti, Luc Reymond, Miwa Umebayashi, Ruud Hovius, Howard Riezman, Kai Johnsson. A fluorogenic probe for SNAP-tagged plasma membrane proteins based on the solvatochromic molecule Nile Red.
ACS chemical biology.
2014 Mar; 9(3):606-12. doi:
10.1021/cb400819c. [PMID: 24471525] - Henrik Strahl, Frank Bürmann, Leendert W Hamoen. The actin homologue MreB organizes the bacterial cell membrane.
Nature communications.
2014 Mar; 5(?):3442. doi:
10.1038/ncomms4442. [PMID: 24603761] - Gurpreet Kaur, Surinder K Mehta. Probing location of anti-TB drugs loaded in Brij 96 microemulsions using thermoanalytical and photophysical approach.
Journal of pharmaceutical sciences.
2014 Mar; 103(3):937-44. doi:
10.1002/jps.23857. [PMID: 24425102] - Zeynep E Çakmak, Tolga T Ölmez, Turgay Çakmak, Yusuf Menemen, Turgay Tekinay. Induction of triacylglycerol production in Chlamydomonas reinhardtii: comparative analysis of different element regimes.
Bioresource technology.
2014 Mar; 155(?):379-87. doi:
10.1016/j.biortech.2013.12.093. [PMID: 24472680] - Xian Sun, Yu Cao, Hui Xu, Yan Liu, Jianrui Sun, Dairong Qiao, Yi Cao. Effect of nitrogen-starvation, light intensity and iron on triacylglyceride/carbohydrate production and fatty acid profile of Neochloris oleoabundans HK-129 by a two-stage process.
Bioresource technology.
2014 Mar; 155(?):204-12. doi:
10.1016/j.biortech.2013.12.109. [PMID: 24457305] - Isabel Espinosa-Gonzalez, Archana Parashar, David C Bressler. Heterotrophic growth and lipid accumulation of Chlorella protothecoides in whey permeate, a dairy by-product stream, for biofuel production.
Bioresource technology.
2014 Mar; 155(?):170-6. doi:
10.1016/j.biortech.2013.12.028. [PMID: 24445193] - Iuliia A Karpenko, Rémy Kreder, Christel Valencia, Pascal Villa, Christiane Mendre, Bernard Mouillac, Yves Mély, Marcel Hibert, Dominique Bonnet, Andrey S Klymchenko. Red fluorescent turn-on ligands for imaging and quantifying G protein-coupled receptors in living cells.
Chembiochem : a European journal of chemical biology.
2014 Feb; 15(3):359-63. doi:
10.1002/cbic.201300738. [PMID: 24449564] - Meng Wang, Wenqiao Yuan, Xiaoning Jiang, Yun Jing, Zhuochen Wang. Disruption of microalgal cells using high-frequency focused ultrasound.
Bioresource technology.
2014 Feb; 153(?):315-21. doi:
10.1016/j.biortech.2013.11.054. [PMID: 24374364] - Yuelu Jiang, Katherine Starks Laverty, Jola Brown, Marcella Nunez, Lou Brown, Jennifer Chagoya, Mark Burow, Antonietta Quigg. Effects of fluctuating temperature and silicate supply on the growth, biochemical composition and lipid accumulation of Nitzschia sp.
Bioresource technology.
2014 Feb; 154(?):336-44. doi:
10.1016/j.biortech.2013.12.068. [PMID: 24413451] - Jandora Severo Poli, Hans-Christian Holten Lützhøft, Dimitar Borisov Karakashev, Patricia Valente, Irini Angelidaki. An environmentally-friendly fluorescent method for quantification of lipid contents in yeast.
Bioresource technology.
2014 Jan; 151(?):388-91. doi:
10.1016/j.biortech.2013.09.128. [PMID: 24206637] - Sang Gon Lee, Jae Han Jeong, Kyung Min Lee, Kyu Ho Jeong, Huisuk Yang, Miroo Kim, Hyungil Jung, Sangkil Lee, Young Wook Choi. Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule.
International journal of nanomedicine.
2014; 9(?):289-99. doi:
10.2147/ijn.s54529. [PMID: 24403833] - Steve Dagenais Bellefeuille, Sonia Dorion, Jean Rivoal, David Morse. The dinoflagellate Lingulodinium polyedrum responds to N depletion by a polarized deposition of starch and lipid bodies.
PloS one.
2014; 9(11):e111067. doi:
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