Nephrin (BioDeep_00000181621)
human metabolite blood metabolite
代谢物信息卡片
3-(2-Hydroxypropan-2-yl)-5a,5b,8,8,11a,13b-hexamethyl-1,2,3,3a,4,5,6,7,7a,9,10,11,11b,12,13,13a-hexadecahydrocyclopenta[a]chrysene-6,7-diol
化学式: C30H52O3 (460.3916242)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 87.5%
分子结构信息
SMILES: CC(C)(O)C1CCC2(C)C1CCC1(C)C2CCC2C3(C)CCCC(C)(C)C3C(O)C(O)C12C
InChI: InChI=1S/C30H52O3/c1-25(2)14-9-15-28(6)21-11-10-20-27(5)16-12-18(26(3,4)33)19(27)13-17-29(20,7)30(21,8)24(32)22(31)23(25)28/h18-24,31-33H,9-17H2,1-8H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ji Young Kim, Eun Jung Lee, Jimyung Seo, Yangsin Lee, Yuri Ahn, Sujin Park, Yu Jeong Bae, Jinu Lee, Beom Jin Lim, Doyoung Kim, Jin Won Cho, Sang Ho Oh. Nephrin expression in human epidermal keratinocytes and its implication in poor wound closure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2022 Jul; 36(7):e22424. doi:
10.1096/fj.202100455rr. [PMID: 35747929] - Na Wu, Yingchuan Zhu, Wenhao Jiang, Yue Song, Lan Yin, Yilu Lu, Dachang Tao, Yunqiang Liu, Yongxin Ma. A novel NPHS2 mutation (c.865A > G) identified in a Chinese family with steroid-resistant nephrotic syndrome alters subcellular localization of nephrin.
Genes & genomics.
2022 05; 44(5):551-559. doi:
10.1007/s13258-022-01220-5. [PMID: 35099763] - Andrew J B Watts, Keith H Keller, Gabriel Lerner, Ivy Rosales, A Bernard Collins, Miroslav Sekulic, Sushrut S Waikar, Anil Chandraker, Leonardo V Riella, Mariam P Alexander, Jonathan P Troost, Junbo Chen, Damian Fermin, Jennifer L Yee, Matthew G Sampson, Laurence H Beck, Joel M Henderson, Anna Greka, Helmut G Rennke, Astrid Weins. Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology.
Journal of the American Society of Nephrology : JASN.
2022 01; 33(1):238-252. doi:
10.1681/asn.2021060794. [PMID: 34732507] - Mohamed M Zedan, Ahmed K Mansour, Ashraf A Bakr, Mohamed A Sobh, Hesam Khodadadi, Evila Lopes Salles, Abdulmohsin Alhashim, Babak Baban, Olga Golubnitschaja, Ahmed A Elmarakby. Effect of Everolimus versus Bone Marrow-Derived Stem Cells on Glomerular Injury in a Rat Model of Glomerulonephritis: A Preventive, Predictive and Personalized Implication.
International journal of molecular sciences.
2021 Dec; 23(1):. doi:
10.3390/ijms23010344. [PMID: 35008770] - Xin Li, Dong Qi, Meng-Ying Wang, Kai Ji, Qun-Ling Xie, Yu Wang, Shi-Hao Du, Hua-Ying Fan. Salvianolic acid A attenuates steroid resistant nephrotic syndrome through suPAR/uPAR-αvβ3 signaling Inhibition.
Journal of ethnopharmacology.
2021 Oct; 279(?):114351. doi:
10.1016/j.jep.2021.114351. [PMID: 34157324] - Weiwei Liu, Liqiang Shi, Qiang Wan, Yansheng Wu, Di Huang, Jiaoying Ou, Qiuyu Liu, Xin Guan, Yuzhu Yang, Xiaotian Zhang, Jiandong Gao. Huangqi Guizhi Wuwu Decoction attenuates Podocyte cytoskeletal protein damage in IgA nephropathy rats by regulating AT1R/Nephrin/c-Abl pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Oct; 142(?):111907. doi:
10.1016/j.biopha.2021.111907. [PMID: 34339916] - Mariana Charleaux de Ponte, Vanessa Gerolde Cardoso, Guilherme Lopes Gonçalves, Juliana Martins Costa-Pessoa, Maria Oliveira-Souza. Early type 1 diabetes aggravates renal ischemia/reperfusion-induced acute kidney injury.
Scientific reports.
2021 09; 11(1):19028. doi:
10.1038/s41598-021-97839-7. [PMID: 34561469] - Ashish K Solanki, Ehtesham Arif, Pankaj Srivastava, Christopher M Furcht, Bushra Rahman, Pei Wen, Avinash Singh, Lawrence B Holzman, Wayne R Fitzgibbon, Milos N Budisavljevic, Glenn P Lobo, Sang-Ho Kwon, Zhe Han, Matthew J Lazzara, Joshua H Lipschutz, Deepak Nihalani. Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair.
The Journal of biological chemistry.
2021 09; 297(3):101079. doi:
10.1016/j.jbc.2021.101079. [PMID: 34391780] - Florian Tesch, Florian Siegerist, Eleonora Hay, Nadine Artelt, Christoph Daniel, Kerstin Amann, Uwe Zimmermann, Panagiotis Kavvadas, Olaf Grisk, Christos Chadjichristos, Karlhans Endlich, Christos Chatziantoniou, Nicole Endlich. Super-resolved local recruitment of CLDN5 to filtration slits implicates a direct relationship with podocyte foot process effacement.
Journal of cellular and molecular medicine.
2021 08; 25(16):7631-7641. doi:
10.1111/jcmm.16519. [PMID: 34156149] - Placido Rojas-Franco, Margarita Franco-Colín, Vanessa Blas-Valdivia, María Estela Melendez-Camargo, Edgar Cano-Europa. Arthrospira maxima (Spirulina) prevents endoplasmic reticulum stress in the kidney through its C-phycocyanin.
Journal of Zhejiang University. Science. B.
2021 Jul; 22(7):603-608. doi:
10.1631/jzus.b2000725. [PMID: 34269013] - Jung-Joo Yoon, Ji-Hun Park, Yun-Jung Lee, Hye-Yoom Kim, Byung-Hyuk Han, Hong-Guang Jin, Dae-Gill Kang, Ho-Sub Lee. Protective Effects of Ethanolic Extract from Rhizome of Polygoni avicularis against Renal Fibrosis and Inflammation in a Diabetic Nephropathy Model.
International journal of molecular sciences.
2021 Jul; 22(13):. doi:
10.3390/ijms22137230. [PMID: 34281284] - Terumasa Hashimoto, Keita Shibata, Kazuo Honda, Koji Nobe. Acetic acid treatment causes renal inflammation and chronic kidney disease in mice.
Journal of pharmacological sciences.
2021 Jul; 146(3):160-168. doi:
10.1016/j.jphs.2021.04.002. [PMID: 34030798] - Yoshiyasu Fukusumi, Hidenori Yasuda, Ying Zhang, Hiroshi Kawachi. Nephrin-Ephrin-B1-Na+/H+ Exchanger Regulatory Factor 2-Ezrin-Actin Axis Is Critical in Podocyte Injury.
The American journal of pathology.
2021 07; 191(7):1209-1226. doi:
10.1016/j.ajpath.2021.04.004. [PMID: 33887216] - Rhea Bhargava, Sylvain Lehoux, Kayaho Maeda, Maria G Tsokos, Suzanne Krishfield, Lena Ellezian, Martin Pollak, Isaac E Stillman, Richard D Cummings, George C Tsokos. Aberrantly glycosylated IgG elicits pathogenic signaling in podocytes and signifies lupus nephritis.
JCI insight.
2021 05; 6(9):. doi:
10.1172/jci.insight.147789. [PMID: 33784256] - Annika Möller-Kerutt, Juan E Rodriguez-Gatica, Karin Wacker, Rohan Bhatia, Jan-Peter Siebrasse, Nanda Boon, Veerle Van Marck, Peter Boor, Ulrich Kubitscheck, Jan Wijnholds, Hermann Pavenstädt, Thomas Weide. Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier.
Journal of the American Society of Nephrology : JASN.
2021 05; 32(5):1053-1070. doi:
10.1681/asn.2020040501. [PMID: 33687977] - Khamisa Almokali, Ali Alyami, Abdulaziz Ajeebi, Turki Almutairi, Marwh Aldriwesh. The Frequency of Genetic Mutations in Pediatric Patients Diagnosed with Nephrotic Syndrome: A Single-Center Retrospective Study in Saudi Arabia.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2021 May; 32(3):798-805. doi:
10.4103/1319-2442.336776. [PMID: 35102923] - Sei Yoshida, Xiaoqiong Wei, Gensheng Zhang, Christopher L O'Connor, Mauricio Torres, Zhangsen Zhou, Liangguang Lin, Rajasree Menon, Xiaoxi Xu, Wenyue Zheng, Yi Xiong, Edgar Otto, Chih-Hang Anthony Tang, Rui Hua, Rakesh Verma, Hiroyuki Mori, Yang Zhang, Chih-Chi Andrew Hu, Ming Liu, Puneet Garg, Jeffrey B Hodgin, Shengyi Sun, Markus Bitzer, Ling Qi. Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function.
The Journal of clinical investigation.
2021 04; 131(7):. doi:
10.1172/jci143988. [PMID: 33591954] - Faik Imeri, Bisera Stepanovska Tanturovska, Stephanie Schwalm, Sarbari Saha, Jinyang Zeng-Brouwers, Herrmann Pavenstädt, Josef Pfeilschifter, Liliana Schaefer, Andrea Huwiler. Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice.
Matrix biology : journal of the International Society for Matrix Biology.
2021 04; 98(?):32-48. doi:
10.1016/j.matbio.2021.05.003. [PMID: 34015468] - Stefanie Heiden, Rebecca Siwek, Marie-Luise Lotz, Sarah Borkowsky, Rita Schröter, Pavel Nedvetsky, Astrid Rohlmann, Markus Missler, Michael P Krahn. Apical-basal polarity regulators are essential for slit diaphragm assembly and endocytosis in Drosophila nephrocytes.
Cellular and molecular life sciences : CMLS.
2021 Apr; 78(7):3657-3672. doi:
10.1007/s00018-021-03769-y. [PMID: 33651172] - Karina Thieme, Beatriz Maria Veloso Pereira, Karolline S da Silva, Nelly T Fabre, Sérgio Catanozi, Marisa Passarelli, Maria Lucia Correa-Giannella. Chronic advanced-glycation end products treatment induces TXNIP expression and epigenetic changes in glomerular podocytes in vivo and in vitro.
Life sciences.
2021 Apr; 270(?):118997. doi:
10.1016/j.lfs.2020.118997. [PMID: 33453249] - Tomoko Ohmori, Shankhajit De, Shunsuke Tanigawa, Koichiro Miike, Mazharul Islam, Minami Soga, Takumi Era, Shinichi Shiona, Koichi Nakanishi, Hitoshi Nakazato, Ryuichi Nishinakamura. Impaired NEPHRIN localization in kidney organoids derived from nephrotic patient iPS cells.
Scientific reports.
2021 02; 11(1):3982. doi:
10.1038/s41598-021-83501-9. [PMID: 33597637] - Lucia C S Wunderlich, Florian Ströhl, Stefan Ströhl, Oliver Vanderpoorten, Luca Mascheroni, Clemens F Kaminski. Superresolving the kidney-a practical comparison of fluorescence nanoscopy of the glomerular filtration barrier.
Analytical and bioanalytical chemistry.
2021 Feb; 413(4):1203-1214. doi:
10.1007/s00216-020-03084-8. [PMID: 33277998] - Gizem Yıldız, Meral Torun Bayram, Alper Soylu, Salih Kavukçu. A novel NPHS1 mutation associated with temporary elevation of maternal serum alfa-fetoprotein and late onset of proteinuria.
International urology and nephrology.
2021 Feb; 53(2):391-392. doi:
10.1007/s11255-020-02645-1. [PMID: 32944892] - Jiarui Han, Yage Zhang, Xiujie Shi, Zining Peng, Yufeng Xing, Xinxin Pang. Tongluo Digui decoction treats renal injury in diabetic rats by promoting autophagy of podocytes.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2021 02; 41(1):125-132. doi:
10.19852/j.cnki.jtcm.2021.01.014. [PMID: 33522205] - Akankwasa Gilbert, An Changjuan, Cheng Guixue, Liu Jianhua, Qin Xiaosong. Urinary Matrix Metalloproteinase-9 and Nephrin in Idiopathic Membranous Nephropathy: A Cross-Sectional Study.
Disease markers.
2021; 2021(?):1620545. doi:
10.1155/2021/1620545. [PMID: 34707724] - Ning Gao, Yuzhen Zhang, Li Li, Lei Lei, Ping Cao, Xuan Zhao, Lin Lin, Rui Xu. Hyperhomocysteinemia-Induced Oxidative Stress Aggravates Renal Damage in Hypertensive Rats.
American journal of hypertension.
2020 12; 33(12):1127-1135. doi:
10.1093/ajh/hpaa086. [PMID: 32484231] - Ryo Matsuura, Atsuko Hiraishi, Lawrence B Holzman, Hiroki Hanayama, Koji Harano, Eiichi Nakamura, Yoshifumi Hamasaki, Kent Doi, Masaomi Nangaku, Eisei Noiri. SHROOM3, the gene associated with chronic kidney disease, affects the podocyte structure.
Scientific reports.
2020 12; 10(1):21103. doi:
10.1038/s41598-020-77952-9. [PMID: 33273487] - Christian Nusshag, Alisa Stütz, Stefan Hägele, Claudius Speer, Florian Kälble, Christoph Eckert, Thorsten Brenner, Markus A Weigand, Christian Morath, Jochen Reiser, Martin Zeier, Ellen Krautkrämer. Glomerular filtration barrier dysfunction in a self-limiting, RNA virus-induced glomerulopathy resembles findings in idiopathic nephrotic syndromes.
Scientific reports.
2020 11; 10(1):19117. doi:
10.1038/s41598-020-76050-0. [PMID: 33154421] - Bassam Saeed. Genetic screening in children with challenging nephrotic syndrome.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2020 Nov; 31(6):1189-1197. doi:
10.4103/1319-2442.308327. [PMID: 33565430] - Ning Gao, Yuzhen Zhang, Lei Lei, Li Li, Ping Cao, Xuan Zhao, Lin Lin, Rui Xu. Low doses of folic acid can reduce hyperhomocysteinemia-induced glomerular injury in spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension.
2020 11; 43(11):1182-1191. doi:
10.1038/s41440-020-0471-8. [PMID: 32439914] - Xiaoyuan Jia, Tomohiko Yamamura, Rasheed Gbadegesin, Michelle T McNulty, Kyuyong Song, China Nagano, Yuki Hitomi, Dongwon Lee, Yoshihiro Aiba, Seik-Soon Khor, Kazuko Ueno, Yosuke Kawai, Masao Nagasaki, Eisei Noiri, Tomoko Horinouchi, Hiroshi Kaito, Riku Hamada, Takayuki Okamoto, Koichi Kamei, Yoshitsugu Kaku, Rika Fujimaru, Ryojiro Tanaka, Yuko Shima, Jiwon Baek, Hee Gyung Kang, Il-Soo Ha, Kyoung Hee Han, Eun Mi Yang, Asiri Abeyagunawardena, Brandon Lane, Megan Chryst-Stangl, Christopher Esezobor, Adaobi Solarin, Claire Dossier, Georges Deschênes, Marina Vivarelli, Hanna Debiec, Kenji Ishikura, Masafumi Matsuo, Kandai Nozu, Pierre Ronco, Hae Il Cheong, Matthew G Sampson, Katsushi Tokunaga, Kazumoto Iijima. Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.
Kidney international.
2020 11; 98(5):1308-1322. doi:
10.1016/j.kint.2020.05.029. [PMID: 32554042] - Sergi Clotet-Freixas, Caitriona M McEvoy, Ihor Batruch, Chiara Pastrello, Max Kotlyar, Julie Anh Dung Van, Madhurangi Arambewela, Alex Boshart, Sofia Farkona, Yun Niu, Yanhong Li, Olusegun Famure, Andrea Bozovic, Vathany Kulasingam, Peixuen Chen, S Joseph Kim, Emilie Chan, Sajad Moshkelgosha, Syed Ashiqur Rahman, Jishnu Das, Tereza Martinu, Stephen Juvet, Igor Jurisica, Andrzej Chruscinski, Rohan John, Ana Konvalinka. Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study.
Journal of the American Society of Nephrology : JASN.
2020 11; 31(11):2705-2724. doi:
10.1681/asn.2020030286. [PMID: 32900843] - Xiaowen Chen, Wenting Liu, Jing Xiao, Ying Zhang, Yihua Chen, Congwei Luo, Qianyin Huang, Fenfen Peng, Wangqiu Gong, Shuting Li, Xiaoyang He, Yiyi Zhuang, Na Wu, Yanxia Liu, Yuxian Wang, Haibo Long. FOXO3a accumulation and activation accelerate oxidative stress-induced podocyte injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2020 10; 34(10):13300-13316. doi:
10.1096/fj.202000783r. [PMID: 32786113] - Mingjuan He, Yixiang Li, Li Wang, Bei Guo, Wen Mei, Biao Zhu, Jiajia Zhang, Yan Ding, Biying Meng, Liming Zhang, Lin Xiang, Jing Dong, Min Liu, Lingwei Xiang, Guangda Xiang. MYDGF attenuates podocyte injury and proteinuria by activating Akt/BAD signal pathway in mice with diabetic kidney disease.
Diabetologia.
2020 09; 63(9):1916-1931. doi:
10.1007/s00125-020-05197-2. [PMID: 32588068] - Luis Gustavo Farias Sousa, Lôrrainy Umbelina Alves de Souza Cortez, Janaína Serra Azul Monteiro Evangelista, Francisco Antônio Félix Xavier-Júnior, Douglas Biggam Heimark, Manassés Claudino Fonteles, Claudia Ferreira Santos, Nilberto Robson Falcão Nascimento. Renal protective effect of pinitol in experimental diabetes.
European journal of pharmacology.
2020 Aug; 880(?):173130. doi:
10.1016/j.ejphar.2020.173130. [PMID: 32360975] - Di Feng. Phosphorylation of key podocyte proteins and the association with proteinuric kidney disease.
American journal of physiology. Renal physiology.
2020 08; 319(2):F284-F291. doi:
10.1152/ajprenal.00002.2020. [PMID: 32686524] - Yacheng Xiong, Wei Zhu, Qian Xu, Rexiati Ruze, Zhibo Yan, Jianwen Li, Sanyuan Hu, Mingwei Zhong, Yugang Cheng, Guangyong Zhang. Sleeve Gastrectomy Attenuates Diabetic Nephropathy by Upregulating Nephrin Expressions in Diabetic Obese Rats.
Obesity surgery.
2020 08; 30(8):2893-2904. doi:
10.1007/s11695-020-04611-3. [PMID: 32399849] - Irena Audzeyenka, Patrycja Rachubik, Dorota Rogacka, Marlena Typiak, Tomasz Kulesza, Stefan Angielski, Michał Rychłowski, Magdalena Wysocka, Natalia Gruba, Adam Lesner, Moin A Saleem, Agnieszka Piwkowska. Cathepsin C is a novel mediator of podocyte and renal injury induced by hyperglycemia.
Biochimica et biophysica acta. Molecular cell research.
2020 08; 1867(8):118723. doi:
10.1016/j.bbamcr.2020.118723. [PMID: 32302668] - Xiqian Lan, Vinod Kumar, Alok Jha, Rukhsana Aslam, Haichao Wang, Kehong Chen, Yueming Yu, Weimei He, Feilan Chen, Huairong Luo, Ashwani Malhotra, Pravin C Singhal. EDA2R mediates podocyte injury in high glucose milieu.
Biochimie.
2020 Jul; 174(?):74-83. doi:
10.1016/j.biochi.2020.04.003. [PMID: 32304771] - Ivona Kosovic, Natalija Filipovic, Benjamin Benzon, Katarina Vukojevic, Marijan Saraga, Merica Glavina Durdov, Ivana Bocina, Mirna Saraga-Babic. Spatio-temporal patterning of different connexins in developing and postnatal human kidneys and in nephrotic syndrome of the Finnish type (CNF).
Scientific reports.
2020 05; 10(1):8756. doi:
10.1038/s41598-020-65777-5. [PMID: 32471989] - Yuexin Tian, Huifang Guo, Xinyan Miao, Jie Xu, Ran Yang, Lu Zhao, Jinxi Liu, Lin Yang, Fan Gao, Wei Zhang, Qingjuan Liu, Shaoguang Sun, Yu Tian, Hongbo Li, Jie Huang, Cunyang Gu, Shuxia Liu, Xiaojuan Feng. Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress.
Cell death & disease.
2020 05; 11(5):319. doi:
10.1038/s41419-020-2547-4. [PMID: 32371936] - Lajos Markó, Joon-Keun Park, Norbert Henke, Song Rong, András Balogh, Samuel Klamer, Hendrik Bartolomaeus, Nicola Wilck, Jürgen Ruland, Sofia K Forslund, Friedrich C Luft, Ralf Dechend, Dominik N Müller. B-cell lymphoma/leukaemia 10 and angiotensin II-induced kidney injury.
Cardiovascular research.
2020 04; 116(5):1059-1070. doi:
10.1093/cvr/cvz169. [PMID: 31241148] - Min-You Qi, Xu-Tao Wang, Hui-Lin Xu, Zhang-Liang Yang, Yin Cheng, Bin Zhou. Protective effect of ferulic acid on STZ-induced diabetic nephropathy in rats.
Food & function.
2020 Apr; 11(4):3706-3718. doi:
10.1039/c9fo02398d. [PMID: 32307498] - Yuanyuan Hu, Shandong Ye, Yan Xing, Lijuan Lv, Wen Hu, Wan Zhou. Saxagliptin attenuates glomerular podocyte injury by increasing the expression of renal nephrin and podocin in type 2 diabetic rats.
Acta diabetologica.
2020 Mar; 57(3):279-286. doi:
10.1007/s00592-019-01421-7. [PMID: 31535208] - Akihiro Minakawa, Akihiro Fukuda, Masao Kikuchi, Yuji Sato, Yuichiro Sato, Kazuo Kitamura, Shouichi Fujimoto. Urinary podocyte mRNA is a potent biomarker of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.
Clinical and experimental nephrology.
2020 Mar; 24(3):242-252. doi:
10.1007/s10157-019-01823-5. [PMID: 31768862] - Akihito Hishikawa, Kaori Hayashi, Norifumi Yoshimoto, Ran Nakamichi, Koichiro Homma, Hiroshi Itoh. DNA damage and expression of DNA methylation modulators in urine-derived cells of patients with hypertension and diabetes.
Scientific reports.
2020 02; 10(1):3377. doi:
10.1038/s41598-020-60420-9. [PMID: 32099032] - Sayuri Takamura, Yoshiyasu Fukusumi, Ying Zhang, Ichiei Narita, Hiroshi Kawachi. Partitioning-Defective-6-Ephrin-B1 Interaction Is Regulated by Nephrin-Mediated Signal and Is Crucial in Maintaining Slit Diaphragm of Podocyte.
The American journal of pathology.
2020 02; 190(2):333-346. doi:
10.1016/j.ajpath.2019.10.015. [PMID: 31837290] - Md Abdul Masum, Osamu Ichii, Yaser Hosny Ali Elewa, Yasuhiro Kon. Podocyte Injury Through Interaction Between Tlr8 and Its Endogenous Ligand miR-21 in Obstructed and Its Collateral Kidney.
Frontiers in immunology.
2020; 11(?):606488. doi:
10.3389/fimmu.2020.606488. [PMID: 33552064] - Felipe Mateus Ornellas, Rodrigo J Ramalho, Camilla Fanelli, Margoth Ramos Garnica, Denise M A C Malheiros, Sabrina Vargas Martini, Marcelo Marcos Morales, Irene L Noronha. Mesenchymal Stromal Cells Induce Podocyte Protection in the Puromycin Injury Model.
Scientific reports.
2019 12; 9(1):19604. doi:
10.1038/s41598-019-55284-7. [PMID: 31862892] - Roderick J Tan, Yingjian Li, Brittney M Rush, Débora Malta Cerqueira, Dong Zhou, Haiyan Fu, Jacqueline Ho, Donna Beer Stolz, Youhua Liu. Tubular injury triggers podocyte dysfunction by β-catenin-driven release of MMP-7.
JCI insight.
2019 12; 4(24):. doi:
10.1172/jci.insight.122399. [PMID: 31743113] - Oleg Palygin, Denisha Spires, Vladislav Levchenko, Ruslan Bohovyk, Mykhailo Fedoriuk, Christine A Klemens, Olga Sykes, John D Bukowy, Allen W Cowley, Jozef Lazar, Daria V Ilatovskaya, Alexander Staruschenko. Progression of diabetic kidney disease in T2DN rats.
American journal of physiology. Renal physiology.
2019 12; 317(6):F1450-F1461. doi:
10.1152/ajprenal.00246.2019. [PMID: 31566426] - Lina L Kampf, Ronen Schneider, Lea Gerstner, Roland Thünauer, Mengmeng Chen, Martin Helmstädter, Ali Amar, Ana C Onuchic-Whitford, Reyner Loza Munarriz, Afig Berdeli, Dominik Müller, Eva Schrezenmeier, Klemens Budde, Shrikant Mane, Kristen M Laricchia, Heidi L Rehm, Daniel G MacArthur, Richard P Lifton, Gerd Walz, Winfried Römer, Carsten Bergmann, Friedhelm Hildebrandt, Tobias Hermle. TBC1D8B Mutations Implicate RAB11-Dependent Vesicular Trafficking in the Pathogenesis of Nephrotic Syndrome.
Journal of the American Society of Nephrology : JASN.
2019 12; 30(12):2338-2353. doi:
10.1681/asn.2019040414. [PMID: 31732614] - Shangmei Cao, Wenjing Huang, Zhuo Yu, Xin Yang, Na Liu, Tianjiang Ma, Shuifu Tang, Lifan Wang. Effect of shenyan xiaobai granule on nephrin and podocin of adriamycin-induced renal injury: A randomised controlled trial.
Journal of ethnopharmacology.
2019 Nov; 244(?):112104. doi:
10.1016/j.jep.2019.112104. [PMID: 31394178] - Soyeon Kim, Joseph M Kalappurakkal, Satyajit Mayor, Michael K Rosen. Phosphorylation of nephrin induces phase separated domains that move through actomyosin contraction.
Molecular biology of the cell.
2019 11; 30(24):2996-3012. doi:
10.1091/mbc.e18-12-0823. [PMID: 31599693] - Shengyi Gu, Huaxiang Shen, Yun Zhou, Jiaying Ni, Tao Zheng, Zhengqian Mou, Xiaolin Hua. Tetramethylpyrazine reduces the consequences of nitric oxide inhibition in pregnant rats.
Journal of cellular physiology.
2019 11; 234(11):19799-19806. doi:
10.1002/jcp.28579. [PMID: 30937928] - Feng Wan, Ru-Chun Yang, Yan-Peng Shi, Yue-Wen Tang, Xuan-Li Tang, Xiao-Ling Zhu, You-Gui Li, Yong-Jun Wang. The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats.
BMC complementary and alternative medicine.
2019 Oct; 19(1):272. doi:
10.1186/s12906-019-2705-3. [PMID: 31638956] - Yanan Zhu, Haiyun Chen, Xiaoqi Zhao, Bin Li, Hangyuan He, Hui Cheng, Hui Wang, Ying Ao. Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats.
Toxicology letters.
2019 Oct; 314(?):63-74. doi:
10.1016/j.toxlet.2019.07.011. [PMID: 31306741] - Ashish K Solanki, Eugen Widmeier, Ehtesham Arif, Shailza Sharma, Ankana Daga, Pankaj Srivastava, Sang-Ho Kwon, Hannah Hugo, Makiko Nakayama, Nina Mann, Amar J Majmundar, Wei Tan, Heon Yung Gee, Caroline E Sadowski, Choni Rinat, Rachel Becker-Cohen, Carsten Bergmann, Seymour Rosen, Michael Somers, Shirlee Shril, Tobias B Huber, Shrikant Mane, Friedhelm Hildebrandt, Deepak Nihalani. Mutations in KIRREL1, a slit diaphragm component, cause steroid-resistant nephrotic syndrome.
Kidney international.
2019 10; 96(4):883-889. doi:
10.1016/j.kint.2019.06.016. [PMID: 31472902] - Hüseyin Kocatürk, Nursen Atasoy, Fevzi Bedir, İbrahim Karabulut, Engin Şebin, Kemal Sarica. Evaluation of the urinary podocalyxin and nephrin excretion levels to determine a safe time interval between two sessions of SWL for renal stones: a non randomized exploratory study.
International urology and nephrology.
2019 Oct; 51(10):1727-1734. doi:
10.1007/s11255-019-02229-8. [PMID: 31321677] - Tomohiko Yamamura, Kandai Nozu, Shogo Minamikawa, Tomoko Horinouchi, Nana Sakakibara, China Nagano, Yuya Aoto, Shinya Ishiko, Koichi Nakanishi, Yuko Shima, Hiroaki Nagase, Rini Rossanti, Ming J Ye, Yoshimi Nozu, Shingo Ishimori, Naoya Morisada, Hiroshi Kaito, Kazumoto Iijima. Comparison between conventional and comprehensive sequencing approaches for genetic diagnosis of Alport syndrome.
Molecular genetics & genomic medicine.
2019 09; 7(9):e883. doi:
10.1002/mgg3.883. [PMID: 31364286] - Natalya V Kaverina, Diana G Eng, Benjamin S Freedman, J Nathan Kutz, Tyler J Chozinski, Joshua C Vaughan, Jeffrey H Miner, Jeffrey W Pippin, Stuart J Shankland. Dual lineage tracing shows that glomerular parietal epithelial cells can transdifferentiate toward the adult podocyte fate.
Kidney international.
2019 09; 96(3):597-611. doi:
10.1016/j.kint.2019.03.014. [PMID: 31200942] - Julie Bernardor, Camille Faudeux, Anabelle Chaussenot, Corinne Antignac, Alice Goldenberg, Marie Claire Gubler, Nicole Wagner, Etienne Bérard. Nephrotic syndrome and mitochondrial disorders: Questions.
Pediatric nephrology (Berlin, Germany).
2019 08; 34(8):1373-1374. doi:
10.1007/s00467-019-04216-8. [PMID: 30863910] - Kentaro Nishi, Tomohiro Inoguchi, Koichi Kamei, Riku Hamada, Hiroshi Hataya, Masao Ogura, Mai Sato, Takako Yoshioka, Kentaro Ogata, Shuichi Ito, Koichi Nakanishi, Kandai Nozu, Yuko Hamasaki, Kenji Ishikura. Detailed clinical manifestations at onset and prognosis of neonatal-onset Denys-Drash syndrome and congenital nephrotic syndrome of the Finnish type.
Clinical and experimental nephrology.
2019 Aug; 23(8):1058-1065. doi:
10.1007/s10157-019-01732-7. [PMID: 30963316] - Guixiang Chen, Xiaohong Jin, Lihong Zhang, Jianying Niu, Yong Gu. Decreased Ang-(1-7) and Downregulated Intrarenal RAS May Contribute to the Direct Podocyte Injury With Proteinuria in Preeclampsia.
Reproductive sciences (Thousand Oaks, Calif.).
2019 08; 26(8):1146-1157. doi:
10.1177/1933719118813200. [PMID: 30595084] - T-T Liao, L-B Zhao, H Liu, R-L He, Y-Q Wang, J Li. Liraglutide protects from renal damage via Akt-mTOR pathway in rats with diabetic kidney disease.
European review for medical and pharmacological sciences.
2019 Aug; 23(3 Suppl):117-125. doi:
10.26355/eurrev_201908_18638. [PMID: 31389583] - Müslüm Kuzu, Serkan Yıldırım, Fatih Mehmet Kandemir, Sefa Küçükler, Cüneyt Çağlayan, Erdinç Türk, Muhammet Bahaeddin Dörtbudak. Protective effect of morin on doxorubicin-induced hepatorenal toxicity in rats.
Chemico-biological interactions.
2019 Aug; 308(?):89-100. doi:
10.1016/j.cbi.2019.05.017. [PMID: 31100273] - Stephanie Dufek, Tuula Holtta, Agnes Trautmann, Elisa Ylinen, Harika Alpay, Gema Ariceta, Christoph Aufricht, Justine Bacchetta, Sevcan A Bakkaloglu, Aysun Bayazit, Rumeysa Yasemin Cicek, Ismail Dursun, Ali Duzova, Mesiha Ekim, Daniela Iancu, Augustina Jankauskiene, Günter Klaus, Fabio Paglialonga, Andrea Pasini, Nikoleta Printza, Valerie Said Conti, Maria do Sameiro Faria, Claus Peter Schmitt, Constantinos J Stefanidis, Enrico Verrina, Enrico Vidal, Karel Vondrak, Hazel Webb, Argyroula Zampetoglou, Detlef Bockenhauer, Alberto Edefonti, Rukshana Shroff. Management of children with congenital nephrotic syndrome: challenging treatment paradigms.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2019 08; 34(8):1369-1377. doi:
10.1093/ndt/gfy165. [PMID: 30215773] - Julie Bernardor, Camille Faudeux, Anabelle Chaussenot, Corinne Antignac, Alice Goldenberg, Marie Claire Gubler, Nicole Wagner, Etienne Bérard. Nephrotic syndrome and mitochondrial disorders: answers.
Pediatric nephrology (Berlin, Germany).
2019 08; 34(8):1375-1377. doi:
10.1007/s00467-019-04217-7. [PMID: 30863911] - Xiaodan Cao, Renxiong Wei, Jun Zhou, Xiaoxia Zhang, Wenbo Gong, Tinglong Jin, Xiabo Chen. Wenshen Jianpi recipe, a blended traditional Chinese medicine, ameliorates proteinuria and renal injury in a rat model of diabetic nephropathy.
BMC complementary and alternative medicine.
2019 Jul; 19(1):193. doi:
10.1186/s12906-019-2598-1. [PMID: 31362740] - Eugenel B Espiritu, Huajun Jiang, Sophie Moreau-Marquis, Mara Sullivan, Kunimasa Yan, Donna Beer Stolz, Matthew G Sampson, Neil A Hukriede, Agnieszka Swiatecka-Urban. The human nephrin Y1139RSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development.
The Journal of biological chemistry.
2019 07; 294(28):10773-10788. doi:
10.1074/jbc.ra119.008235. [PMID: 31152064] - Dong Zhao, Zheng Liu, Heng Zhang. The protective effect of the TUG1/miR‑197/MAPK1 axis on lipopolysaccharide‑induced podocyte injury.
Molecular medicine reports.
2019 Jul; 20(1):49-56. doi:
10.3892/mmr.2019.10216. [PMID: 31115515] - Ayesha Ghayur, Manreet Kaur Padwal, Limin Liu, Jing Zhang, Peter J Margetts. SMAD3-dependent and -independent pathways in glomerular injury associated with experimental glomerulonephritis.
American journal of physiology. Renal physiology.
2019 07; 317(1):F152-F162. doi:
10.1152/ajprenal.00406.2018. [PMID: 31141397] - Yipeng Liu, Hong Su, Chaoqun Ma, Dong Ji, Xiaoli Zheng, Ping Wang, Shixiang Zheng, Li Wang, Zunsong Wang, Dongmei Xu. IQGAP1 mediates podocyte injury in diabetic kidney disease by regulating nephrin endocytosis.
Cellular signalling.
2019 07; 59(?):13-23. doi:
10.1016/j.cellsig.2019.03.009. [PMID: 30857827] - Yanyan Guo, Zuying Xiong, Xiaoqiang Guo. Histone demethylase KDM6B regulates human podocyte differentiation in vitro.
The Biochemical journal.
2019 06; 476(12):1741-1751. doi:
10.1042/bcj20180968. [PMID: 31138771] - Mengying He, Jin Wang, Zhongwei Yin, Yanru Zhao, Huiying Hou, Jiahui Fan, Huaping Li, Zheng Wen, Jiarong Tang, Yan Wang, Dao Wen Wang, Chen Chen. MiR-320a induces diabetic nephropathy via inhibiting MafB.
Aging.
2019 05; 11(10):3055-3079. doi:
10.18632/aging.101962. [PMID: 31102503] - Malgorzata Kasztan, Brandon M Fox, Jeffrey D Lebensburger, Kelly A Hyndman, Joshua S Speed, Jennifer S Pollock, David M Pollock. Hyperfiltration predicts long-term renal outcomes in humanized sickle cell mice.
Blood advances.
2019 05; 3(9):1460-1475. doi:
10.1182/bloodadvances.2018028878. [PMID: 31064747] - Huimin Yang, Tingting Xie, Dengren Li, Xianhong Du, Tixiao Wang, Chunyang Li, Xiaojia Song, Leiqi Xu, Fan Yi, Xiaohong Liang, Lifen Gao, Xiangdong Yang, Chunhong Ma. Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway.
Molecular metabolism.
2019 05; 23(?):24-36. doi:
10.1016/j.molmet.2019.02.007. [PMID: 30862474] - Chun-Liang Lin, Yung-Chien Hsu, Yu-Ting Huang, Ya-Hsueh Shih, Ching-Jen Wang, Wen-Chih Chiang, Pey-Jium Chang. A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction.
EMBO molecular medicine.
2019 05; 11(5):. doi:
10.15252/emmm.201809828. [PMID: 30948420] - Xiao-Qing Yang, Yan-Jie Huang, Wen-Sheng Zhai, Xian-Qing Ren, Qing-Yin Guo, Xia Zhang, Meng Yang, Jian Zhang, Ying Ding, Shan Zhu, Tatsuo Yamamoto, Yuan Sun. Correlation between endocapillary proliferative and nephrotic-range proteinuria in children with Henoch-Schönlein purpura nephritis.
Pediatric nephrology (Berlin, Germany).
2019 04; 34(4):663-670. doi:
10.1007/s00467-018-4134-9. [PMID: 30415419] - Bing Qiu, Xia Gao, Wei-Jing Cui, Xiao-Yan Lei, Chen-Hao Niu, Hua-Jie Liu, Ming Zhang, Qing-Ju Liu. [Dexamethasone Blocks Adriamycin-induced Podocytes'Mobility via Impacting Nephrin Expression].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2019 Mar; 50(2):197-202. doi:
NULL. [PMID: 31106539] - Sandra Bérody, Laurence Heidet, Olivier Gribouval, Jérome Harambat, Patrick Niaudet, Veronique Baudouin, Justine Bacchetta, Bernard Boudaillez, Maud Dehennault, Loïc de Parscau, Olivier Dunand, Hugues Flodrops, Marc Fila, Arnaud Garnier, Ferielle Louillet, Marie-Alice Macher, Adrien May, Elodie Merieau, Françoise Monceaux, Christine Pietrement, Caroline Rousset-Rouvière, Gwenaëlle Roussey, Sophie Taque, Julie Tenenbaum, Tim Ulinski, Rachel Vieux, Ariane Zaloszyc, Vincent Morinière, Rémi Salomon, Olivia Boyer. Treatment and outcome of congenital nephrotic syndrome.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2019 03; 34(3):458-467. doi:
10.1093/ndt/gfy015. [PMID: 29474669] - Kun Ling Ma, Liang Liu, Yang Zhang, Gui Hua Wang, Ze Bo Hu, Pei Pei Chen, Jian Lu, Chen Chen Lu, Tie Kai Gong, Yu Xiang Gong, Bi Cheng Liu. Aspirin attenuates podocyte injury in diabetic rats through overriding cyclooxygenase-2-mediated dysregulation of LDL receptor pathway.
International urology and nephrology.
2019 Mar; 51(3):551-558. doi:
10.1007/s11255-018-2059-7. [PMID: 30604228] - Akihito Hishikawa, Kaori Hayashi, Takaya Abe, Mari Kaneko, Hideki Yokoi, Tatsuhiko Azegami, Mari Nakamura, Norifumi Yoshimoto, Takeshi Kanda, Yusuke Sakamaki, Hiroshi Itoh. Decreased KAT5 Expression Impairs DNA Repair and Induces Altered DNA Methylation in Kidney Podocytes.
Cell reports.
2019 01; 26(5):1318-1332.e4. doi:
10.1016/j.celrep.2019.01.005. [PMID: 30699357] - Jenny Frese, Matthias Kettwig, Hildegard Zappel, Johannes Hofer, Hermann-Josef Gröne, Mato Nagel, Gere Sunder-Plassmann, Renate Kain, Jörg Neuweiler, Oliver Gross. Kidney Injury by Variants in the COL4A5 Gene Aggravated by Polymorphisms in Slit Diaphragm Genes Causes Focal Segmental Glomerulosclerosis.
International journal of molecular sciences.
2019 Jan; 20(3):. doi:
10.3390/ijms20030519. [PMID: 30691124] - Eva Königshausen, Sebastian A Potthoff, Raphael Haase, Catherine Meyer-Schwesinger, Ernest Kaufmann, L Christian Rump, Johannes Stegbauer, Lorenz Sellin, Ivo Quack, Magdalena Woznowski. Isolation of Glomeruli and In Vivo Labeling of Glomerular Cell Surface Proteins.
Journal of visualized experiments : JoVE.
2019 01; ?(143):. doi:
10.3791/58542. [PMID: 30735184] - George C Tsokos, Maria G Tsokos. TARGETING TARGETED TREATMENT FOR IMMUNE AND NON-IMMUNE KIDNEY DISEASES.
Transactions of the American Clinical and Climatological Association.
2019; 130(?):88-99. doi:
NULL. [PMID: 31516171] - Lívia Helena de Morais Pereira, Crislaine Aparecida da Silva, Maria Luíza Gonçalves Dos Reis Monteiro, Liliane Silvano Araújo, Laura Penna Rocha, Marcelo Bernardes da Rocha Reis, Fernando Silva Ramalho, Rosana Rosa Miranda Corrêa, Marcos Vinicius Silva, Marlene Antonia Reis, Juliana Reis Machado. Podocin and uPAR are good biomarkers in cases of Focal and segmental glomerulosclerosis in pediatric renal biopsies.
PloS one.
2019; 14(6):e0217569. doi:
10.1371/journal.pone.0217569. [PMID: 31188898] - Hugo Bernelin, Nathan Mewton, Salim Si-Mohamed, Pierre Croisille, Gilles Rioufol, Eric Bonnefoy-Cudraz, Philippe Douek, Nathalie Dufay, Camille Amaz, Claire Jossan, Michel Ovize, Thomas Bochaton. Neprilysin levels at the acute phase of ST-elevation myocardial infarction.
Clinical cardiology.
2019 Jan; 42(1):32-38. doi:
10.1002/clc.23090. [PMID: 30284298] - Jiao Chen, Gen Li, Sanfeng Wang, Xiaohan Hu, Yunqing Sun, Xiaomei Dai, Zhenjiang Bai, Jian Pan, Xiaozhong Li, Jian Wang, Yanhong Li. Urinary Nephrin as a Biomarker of Glomerular Maturation and Injury Is Associated with Acute Kidney Injury and Mortality in Critically Ill Neonates.
Neonatology.
2019; 116(1):58-66. doi:
10.1159/000499083. [PMID: 30982033] - Shubo Zhai, Lengyue Zhao, Yan Zhang, Qingshan Ma. Interleukin-7 stimulation inhibits nephrin activation and induces podocyte injury.
Biochemical and biophysical research communications.
2018 12; 507(1-4):100-105. doi:
10.1016/j.bbrc.2018.10.173. [PMID: 30454893] - Dong Zhang, Qiu-Xia Han, Ming-Hui Wu, Wan-Jun Shen, Xiao-Li Yang, Jia Guo, Shao-Kang Pan, Zhang-Suo Liu, Li Tang, Guang-Yan Cai, Xiang-Mei Chen, Han-Yu Zhu. Diagnostic Value of Sensitive Biomarkers for Early Kidney Damage in Diabetic Patients with Normoalbuminuria.
Chinese medical journal.
2018 Dec; 131(23):2891-2892. doi:
10.4103/0366-6999.246080. [PMID: 30511700] - Lorna J Hale, Sara E Howden, Belinda Phipson, Andrew Lonsdale, Pei X Er, Irene Ghobrial, Salman Hosawi, Sean Wilson, Kynan T Lawlor, Shahnaz Khan, Alicia Oshlack, Catherine Quinlan, Rachel Lennon, Melissa H Little. 3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening.
Nature communications.
2018 12; 9(1):5167. doi:
10.1038/s41467-018-07594-z. [PMID: 30514835] - Cecilia Boreström, Anna Jonebring, Jing Guo, Henrik Palmgren, Linda Cederblad, Anna Forslöw, Anna Svensson, Magnus Söderberg, Anna Reznichenko, Jenny Nyström, Jaakko Patrakka, Ryan Hicks, Marcello Maresca, Barbara Valastro, Anna Collén. A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery.
Kidney international.
2018 12; 94(6):1099-1110. doi:
10.1016/j.kint.2018.05.003. [PMID: 30072040] - Changliang Xu, Yunjie Miao, Qingmeng Pi, Shouchao Zhu, Furong Li. Fra-2 is a novel candidate drug target expressed in the podocytes of lupus nephritis.
Clinical immunology (Orlando, Fla.).
2018 12; 197(?):179-185. doi:
10.1016/j.clim.2018.10.001. [PMID: 30296590] - Zuokang Zheng, Hong Hu, Yanrong Tong, Zhixia Hu, Shiyu Cao, Ce Shan, Wenhe Lin, Yike Yin, Zhonghan Li. MiR-27b regulates podocyte survival through targeting adenosine receptor 2B in podocytes from non-human primate.
Cell death & disease.
2018 11; 9(11):1133. doi:
10.1038/s41419-018-1178-5. [PMID: 30429458] - Brittney M Rush, Sarah A Small, Donna B Stolz, Roderick J Tan. An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney.
Journal of visualized experiments : JoVE.
2018 11; ?(141):. doi:
10.3791/58162. [PMID: 30451231] - Lei Liu, Lijuan Yang, Baochao Chang, Jiqiang Zhang, Yaling Guo, Xiangdong Yang. The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway.
Renal failure.
2018 Nov; 40(1):492-497. doi:
10.1080/0886022x.2018.1489287. [PMID: 30200803] - Katarina Vukojevic, Fila Raguz, Marijan Saraga, Natalija Filipovic, Ivana Bocina, Darko Kero, Merica Glavina Durdov, Vlatka Martinovic, Mirna Saraga-Babic. Glomeruli from patients with nephrin mutations show increased number of ciliated and poorly differentiated podocytes.
Acta histochemica.
2018 Nov; 120(8):748-756. doi:
10.1016/j.acthis.2018.08.015. [PMID: 30193978] - Chengguo Wei, Khadija Banu, Felipe Garzon, John M Basgen, Nimrod Philippe, Zhengzi Yi, Ruijie Liu, Jui Choudhuri, Miguel Fribourg, Tong Liu, Arun Cumpelik, Jenny Wong, Mubeen Khan, Bhaskar Das, Karen Keung, Fadi Salem, Kirk N Campbell, Lewis Kaufman, Paolo Cravedi, Weijia Zhang, Philip J O'Connell, John Cijiang He, Barbara Murphy, Madhav C Menon. SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts.
Journal of the American Society of Nephrology : JASN.
2018 11; 29(11):2641-2657. doi:
10.1681/asn.2018060573. [PMID: 30341149]