(2S)-4,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-one (BioDeep_00000181444)

   

human metabolite blood metabolite


代谢物信息卡片


4,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-one

化学式: C15H12O8 (320.0532)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(C=C(C(=C1O)O)O)C2C(=O)C(C3=C(C=C(C=C3O2)O)O)O
InChI: InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,13,15-21H

描述信息

同义名列表

3 个代谢物同义名

4,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-one; 4,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,4-dihydro-1-benzopyran-3-one; (2S)-4,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-one



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Tingting Chen, Shajun Zhu, Yapeng Lu, Hui Cao, Yu Zhao, Guoqing Jiang, Li Zhu, Tianhong Lu. Probing the interaction of anti-cancer agent dihydromyricetin with human serum albumin: a typical method study. Anti-cancer agents in medicinal chemistry. 2012 Oct; 12(8):919-28. doi: 10.2174/187152012802650002. [PMID: 22292768]
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  • Yi Shen, A Kerstin Lindemeyer, Claudia Gonzalez, Xuesi M Shao, Igor Spigelman, Richard W Olsen, Jing Liang. Dihydromyricetin as a novel anti-alcohol intoxication medication. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Jan; 32(1):390-401. doi: 10.1523/jneurosci.4639-11.2012. [PMID: 22219299]
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  • Qianqian Gao, Xiufen Yang, Min Ou. [Effect of serum containing tengcha total flavonoid and dihydromyricetin on proliferation and apoptosis of HepG2 cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Feb; 36(4):500-3. doi: 10.4268/cjcmm20110428. [PMID: 21598552]
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  • Lilian Cristina Baldon Aizza, Marcelo Carnier Dornelas. A genomic approach to study anthocyanin synthesis and flower pigmentation in passionflowers. Journal of nucleic acids. 2011; 2011(?):371517. doi: 10.4061/2011/371517. [PMID: 21772993]
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  • Yuepeng Han, Sornkanok Vimolmangkang, Ruth Elena Soria-Guerra, Sergio Rosales-Mendoza, Danman Zheng, Anatoli V Lygin, Schuyler S Korban. Ectopic expression of apple F3'H genes contributes to anthocyanin accumulation in the Arabidopsis tt7 mutant grown under nitrogen stress. Plant physiology. 2010 Jun; 153(2):806-20. doi: 10.1104/pp.109.152801. [PMID: 20357139]
  • Nguyen Thi Mai, Nguyen Xuan Cuong, Nguyen Phuong Thao, Nguyen Hoai Nam, Nguyen Huu Khoi, Chau Van Minh, Yvan Vander Heyden, Ngo Thi Thuan, Nguyen Van Tuyen, Joëlle Quetin-Leclercq, Phan Van Kiem. A new lignan dimer from Mallotus philippensis. Natural product communications. 2010 Mar; 5(3):423-6. doi: . [PMID: 20420321]
  • Ayelet Bar-Akiva, Rinat Ovadia, Ilana Rogachev, Carmiya Bar-Or, Einat Bar, Zohar Freiman, Ada Nissim-Levi, Natan Gollop, Efraim Lewinsohn, Asaph Aharoni, David Weiss, Hinanit Koltai, Michal Oren-Shamir. Metabolic networking in Brunfelsia calycina petals after flower opening. Journal of experimental botany. 2010 Mar; 61(5):1393-403. doi: 10.1093/jxb/erq008. [PMID: 20202996]
  • Kristine M Olsen, Alain Hehn, Hélène Jugdé, Rune Slimestad, Romain Larbat, Frédéric Bourgaud, Cathrine Lillo. Identification and characterisation of CYP75A31, a new flavonoid 3'5'-hydroxylase, isolated from Solanum lycopersicum. BMC plant biology. 2010 Feb; 10(?):21. doi: 10.1186/1471-2229-10-21. [PMID: 20128892]
  • Yongfei Zhang, Shuping Cheng, Darlene De Jong, Helen Griffiths, Rayko Halitschke, Walter De Jong. The potato R locus codes for dihydroflavonol 4-reductase. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2009 Sep; 119(5):931-7. doi: 10.1007/s00122-009-1100-8. [PMID: 19588118]
  • Joost Lücker, Mario Laszczak, Derek Smith, Steven T Lund. Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. BMC genomics. 2009 Jan; 10(?):50. doi: 10.1186/1471-2164-10-50. [PMID: 19171055]
  • Hui Li, Yanan Li, Yongkang Zhang, Hui Shi, Wenbin Hu, Zhaohui Zhang. Comparison of refluxing, ultrasonic- and microwave-assisted extraction of dihydromyricetin from Ampelopsis grossedentata. Journal of AOAC International. 2008 Nov; 91(6):1278-83. doi: 10.1093/jaoac/91.6.1278. [PMID: 19202787]
  • Seong Ho Jeon, Wanjoo Chun, Yong Joon Choi, Yong Soo Kwon. Cytotoxic constituents from the bark of Salix hulteni. Archives of pharmacal research. 2008 Aug; 31(8):978-82. doi: 10.1007/s12272-001-1255-9. [PMID: 18787784]
  • Hossein Nazemiyeh, Fatemeh Bahadori, Abbas Delazar, Mehmet Ay, Gülacti Topçu, Lutfun Nahar, Runner R T Majinda, Satyajit D Sarker. Antioxidant phenolic compounds from the leaves of Erica Arborea (Ericaceae). Natural product research. 2008; 22(16):1385-92. doi: 10.1080/14786410701824007. [PMID: 19023799]
  • Yan-Song Zhang, Qing-ying Zhang, Li-ying Li, Bin Wang, Yu-ying Zhao, De-an Guo. Simultaneous determination and pharmacokinetic studies of dihydromyricetin and myricetin in rat plasma by HPLC-DAD after oral administration of Ampelopsis grossedentata decoction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Dec; 860(1):4-9. doi: 10.1016/j.jchromb.2007.07.049. [PMID: 17996500]
  • Yansong Zhang, Sheng Que, Xiuwei Yang, Bin Wang, Liang Qiao, Yuying Zhao. Isolation and identification of metabolites from dihydromyricetin. Magnetic resonance in chemistry : MRC. 2007 Nov; 45(11):909-16. doi: 10.1002/mrc.2051. [PMID: 17924358]
  • Yunli Zhao, Zhiguo Yu, Lingchao Zhang, Dandan Zhou, Xiaohui Chen, Kaishun Bi. Simultaneous determination of homoeriodictyol-7-O-beta-D-Glccopyranoside and its metabolite homoeriodictyol in rat tissues and urine by liquid chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2007 May; 44(1):293-300. doi: 10.1016/j.jpba.2007.02.016. [PMID: 17382506]
  • Gui-xia He, Wei-li Yang, Gang Pei, Yong-hua Zhu, Fang-lu Du. [Studies on the effect of dihydromyricetin on antilipid-peroxidation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2003 Dec; 28(12):1188-90. doi: ". [PMID: 15617509]
  • You-sheng Zhang, Zheng-xiang Ning, Shu-zhen Yang, Hui Wu. Antioxidation properties and mechanism of action of dihydromyricetin from Ampelopsis grossedentata. Yao xue xue bao = Acta pharmaceutica Sinica. 2003 Apr; 38(4):241-4. doi: ". [PMID: 12889119]
  • Qizhen Du, Weijian Cai, Ming Xia, Yoichiro Ito. Purification of (+)-dihydromyricetin from leaves extract of Ampelopsis grossedentata using high-speed countercurrent chromatograph with scale-up triple columns. Journal of chromatography. A. 2002 Oct; 973(1-2):217-20. doi: 10.1016/s0021-9673(02)01092-0. [PMID: 12437181]
  • Arnaud Bovy, Ric de Vos, Mark Kemper, Elio Schijlen, Maria Almenar Pertejo, Shelagh Muir, Geoff Collins, Sue Robinson, Martine Verhoeyen, Steve Hughes, Celestino Santos-Buelga, Arjen van Tunen. High-flavonol tomatoes resulting from the heterologous expression of the maize transcription factor genes LC and C1. The Plant cell. 2002 Oct; 14(10):2509-26. doi: 10.1105/tpc.004218. [PMID: 12368501]
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