N-Phenylmaleimide (BioDeep_00000181361)

   

human metabolite blood metabolite


代谢物信息卡片


1-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione

化学式: C10H7NO2 (173.0476762)
中文名称: N-苯基马来酰亚胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)N2C(=O)C=CC2=O
InChI: InChI=1S/C10H7NO2/c12-9-6-7-10(13)11(9)8-4-2-1-3-5-8/h1-7H

描述信息

同义名列表

3 个代谢物同义名

1-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione; 1-phenylpyrrole-2,5-dione; N-Phenylmaleimide



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Han Shi, Qixin Zhuang, Anna Zheng, Pengfei Zhan, Yong Guan, Dafu Wei, Xiang Xu, Tao Wu. Antibacterial Mechanism of N-PMI and the Characteristics of PMMA-Co-N-PMI Copolymer. Chemistry & biodiversity. 2022 Jun; 19(6):e202100753. doi: 10.1002/cbdv.202100753. [PMID: 35560720]
  • Andrea Forgacsova, Jaroslav Galba, Jana Mojzisova, Peter Mikus, Juraj Piestansky, Andrej Kovac. Ultra-high performance hydrophilic interaction liquid chromatography - Triple quadrupole tandem mass spectrometry method for determination of cysteine, homocysteine, cysteinyl-glycine and glutathione in rat plasma. Journal of pharmaceutical and biomedical analysis. 2019 Feb; 164(?):442-451. doi: 10.1016/j.jpba.2018.10.053. [PMID: 30447532]
  • Daiane Rosolen, Iara Fabrícia Kretzer, Evelyn Winter, Vânia Floriani Noldin, Ícaro Andrade Rodrigues do Carmo, Fabíola Branco Filippin-Monteiro, Valdir Cechinel-Filho, Tânia Beatriz Creczynski-Pasa. N-phenylmaleimides affect adipogenesis and present antitumor activity through reduction of FASN expression. Chemico-biological interactions. 2016 Oct; 258(?):10-20. doi: 10.1016/j.cbi.2016.08.005. [PMID: 27507602]
  • R James Christie, Ryan Fleming, Binyam Bezabeh, Rob Woods, Shenlan Mao, Jay Harper, Augustine Joseph, Qianli Wang, Ze-Qi Xu, Herren Wu, Changshou Gao, Nazzareno Dimasi. Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides. Journal of controlled release : official journal of the Controlled Release Society. 2015 Dec; 220(Pt B):660-70. doi: 10.1016/j.jconrel.2015.09.032. [PMID: 26387744]
  • D I Rendle, E Litchfield, S Gough, A Cowling, K J Hughes. The effects of sample handling and N-phenylmaleimide on concentration of adrenocorticotrophic hormone in equine plasma. Equine veterinary journal. 2015 Sep; 47(5):587-91. doi: 10.1111/evj.12319. [PMID: 24980684]
  • Michael L Vasil, Andrew P Tomaras, Arthur E Pritchard. Identification and evaluation of twin-arginine translocase inhibitors. Antimicrobial agents and chemotherapy. 2012 Dec; 56(12):6223-34. doi: 10.1128/aac.01575-12. [PMID: 23006747]
  • Dimitra Georgiou, Vasilios Toutountzoglou, Kenneth W Muir, Dimitra Hadjipavlou-Litina, Yiannis Elemes. Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants. Bioorganic & medicinal chemistry. 2012 Sep; 20(17):5103-9. doi: 10.1016/j.bmc.2012.07.014. [PMID: 22858299]
  • John H Livesey, Barbara Dolamore. Stability of plasma adrenocorticotrophic hormone (ACTH): influence of hemolysis, rapid chilling, time, and the addition of a maleimide. Clinical biochemistry. 2010 Dec; 43(18):1478-80. doi: 10.1016/j.clinbiochem.2010.09.020. [PMID: 20875812]
  • Pedro Cabrales, Amy G Tsai, K Ananda, Seetharama A Acharya, Marcos Intaglietta. Volume resuscitation from hemorrhagic shock with albumin and hexaPEGylated human serum albumin. Resuscitation. 2008 Oct; 79(1):139-46. doi: 10.1016/j.resuscitation.2008.04.020. [PMID: 18621463]
  • Judith Martini, Pedro Cabrales, Ananda K, Seetharama A Acharya, Marcos Intaglietta, Amy G Tsai. Survival time in severe hemorrhagic shock after perioperative hemodilution is longer with PEG-conjugated human serum albumin than with HES 130/0.4: a microvascular perspective. Critical care (London, England). 2008; 12(2):R54. doi: 10.1186/cc6874. [PMID: 18423033]
  • H C Schmid, U Oster, J Kögel, S Lenz, W Rüdiger. Cloning and characterisation of chlorophyll synthase from Avena sativa. Biological chemistry. 2001 Jun; 382(6):903-11. doi: 10.1515/bc.2001.112. [PMID: 11501754]
  • M Salomon, J M Christie, E Knieb, U Lempert, W R Briggs. Photochemical and mutational analysis of the FMN-binding domains of the plant blue light receptor, phototropin. Biochemistry. 2000 Aug; 39(31):9401-10. doi: 10.1021/bi000585+. [PMID: 10924135]
  • I Velasco-Guillén, J C Gómez-Fernández, J A Teruel. Characterization of phenylmaleimide inhibition of the Ca(2+)-ATPase from skeletal-muscle sarcoplasmic reticulum. Archives of biochemistry and biophysics. 1999 Dec; 372(1):121-7. doi: 10.1006/abbi.1999.1464. [PMID: 10562424]
  • M Salomon, M Zacherl, W Rudiger. Changes in blue-light-dependent protein phosphorylation during the early development of etiolated oat seedlings. Planta. 1996 Jul; 199(3):336-42. doi: 10.1007/bf00195724. [PMID: 11541069]
  • W Rüdiger, W R Briggs. Involvement of thiol groups in blue-light-induced phosphorylation of a plasma membrane-associated protein from coleoptile tips of Zea mays L. Zeitschrift fur Naturforschung. C, Journal of biosciences. 1995 Mar; 50(3-4):231-4. doi: 10.1515/znc-1995-3-411. [PMID: 7766258]
  • R Addison. The initial association of a truncated form of the Neurospora plasma membrane H(+)-ATPase and of the precursor of yeast invertase with microsomes are distinct processes. Biochimica et biophysica acta. 1993 Oct; 1152(1):119-27. doi: 10.1016/0005-2736(93)90238-u. [PMID: 8399289]
  • N R Miller, S S Simons. Steroid binding to hepatoma tissue culture cell glucocorticoid receptors involves at least two sulfhydryl groups. The Journal of biological chemistry. 1988 Oct; 263(29):15217-25. doi: 10.1016/s0021-9258(18)68167-0. [PMID: 3170579]
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