N-Oleoyldopamine (BioDeep_00000181354)
human metabolite blood metabolite
代谢物信息卡片
N-[2-(3,4-Dihydroxyphenyl)ethyl]octadec-9-enimidate
化学式: C26H43NO3 (417.3242768)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCC=CCCCCCCCC(=O)NCCC1=CC(O)=C(O)C=C1
InChI: InChI=1S/C26H43NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(30)27-21-20-23-18-19-24(28)25(29)22-23/h9-10,18-19,22,28-29H,2-8,11-17,20-21H2,1H3,(H,27,30)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rebecca van der Westen, Leticia Hosta-Rigau, Duncan S Sutherland, Kenneth N Goldie, Fernando Albericio, Almar Postma, Brigitte Städler. Myoblast cell interaction with polydopamine coated liposomes.
Biointerphases.
2012 Dec; 7(1-4):8. doi:
10.1007/s13758-011-0008-4. [PMID: 22589051] - Koppany Visnyei, Hideyuki Onodera, Robert Damoiseaux, Kuniyasu Saigusa, Syuzanna Petrosyan, David De Vries, Denise Ferrari, Jonathan Saxe, Eduard H Panosyan, Michael Masterman-Smith, Jack Mottahedeh, Kenneth A Bradley, Jing Huang, Chiara Sabatti, Ichiro Nakano, Harley I Kornblum. A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells.
Molecular cancer therapeutics.
2011 Oct; 10(10):1818-28. doi:
10.1158/1535-7163.mct-11-0268. [PMID: 21859839] - Shalinee Dhayal, Noel G Morgan. The significance of GPR119 agonists as a future treatment for type 2 diabetes.
Drug news & perspectives.
2010 Sep; 23(7):418-24. doi:
10.1358/dnp.2010.23.7.1468395. [PMID: 20862393] - Carmen M Navarrete, Moisés Pérez, Amaya García de Vinuesa, Juan A Collado, Bernd L Fiebich, Marco A Calzado, Eduardo Muñoz. Endogenous N-acyl-dopamines induce COX-2 expression in brain endothelial cells by stabilizing mRNA through a p38 dependent pathway.
Biochemical pharmacology.
2010 Jun; 79(12):1805-14. doi:
10.1016/j.bcp.2010.02.014. [PMID: 20206142] - Eva Szoke, Rita Börzsei, Dániel Márton Tóth, Orsolya Lengl, Zsuzsanna Helyes, Zoltán Sándor, János Szolcsányi. Effect of lipid raft disruption on TRPV1 receptor activation of trigeminal sensory neurons and transfected cell line.
European journal of pharmacology.
2010 Feb; 628(1-3):67-74. doi:
10.1016/j.ejphar.2009.11.052. [PMID: 19958765] - Zhi-Liang Chu, Chris Carroll, Ruoping Chen, Jean Alfonso, Veronica Gutierrez, Hongmei He, Annette Lucman, Charles Xing, Kristen Sebring, Jinyao Zhou, Brandee Wagner, David Unett, Robert M Jones, Dominic P Behan, James Leonard. N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119.
Molecular endocrinology (Baltimore, Md.).
2010 Jan; 24(1):161-70. doi:
10.1210/me.2009-0239. [PMID: 19901198] - Cassandra I Saunders, Robert G Fassett, Dominic P Geraghty. Up-regulation of TRPV1 in mononuclear cells of end-stage kidney disease patients increases susceptibility to N-arachidonoyl-dopamine (NADA)-induced cell death.
Biochimica et biophysica acta.
2009 Oct; 1792(10):1019-26. doi:
10.1016/j.bbadis.2009.07.008. [PMID: 19619644] - Beihua Zhong, Donna H Wang. N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1.
American journal of physiology. Heart and circulatory physiology.
2008 Aug; 295(2):H728-35. doi:
10.1152/ajpheart.00022.2008. [PMID: 18567714] - Mikhail Yu Bobrov, Anatoly A Lizhin, Ekaterina L Andrianova, Natalia M Gretskaya, Lidia E Frumkina, Leonid G Khaspekov, Vladimir V Bezuglov. Antioxidant and neuroprotective properties of N-arachidonoyldopamine.
Neuroscience letters.
2008 Jan; 431(1):6-11. doi:
10.1016/j.neulet.2007.11.010. [PMID: 18069125] - E Przegaliński, M Filip, D Zajac, M Pokorski. N-oleoyl-dopamine increases locomotor activity in the rat.
International journal of immunopathology and pharmacology.
2006 Oct; 19(4):897-904. doi:
10.1177/039463200601900419. [PMID: 17166411] - D Zajac, Z Matysiak, Z Czarnocki, M Pokorski. Membrane association of N-oleoyl-dopamine in rat brain.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2006 Sep; 57 Suppl 4(?):403-8. doi:
". [PMID: 17072070] - Bruce R Bianchi, Chih-Hung Lee, Michael F Jarvis, Rachid El Kouhen, Robert B Moreland, Connie R Faltynek, Pamela S Puttfarcken. Modulation of human TRPV1 receptor activity by extracellular protons and host cell expression system.
European journal of pharmacology.
2006 May; 537(1-3):20-30. doi:
10.1016/j.ejphar.2006.03.003. [PMID: 16630609] - J Michael Walker, Jocelyn F Krey, Jay S Chen, Eivind Vefring, Jan A Jahnsen, Heather Bradshaw, Susan M Huang. Targeted lipidomics: fatty acid amides and pain modulation.
Prostaglandins & other lipid mediators.
2005 Sep; 77(1-4):35-45. doi:
10.1016/j.prostaglandins.2004.09.017. [PMID: 16099389] - Luciano De Petrocellis, Constance J Chu, Aniello Schiano Moriello, Juliane C Kellner, J Michael Walker, Vincenzo Di Marzo. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels.
British journal of pharmacology.
2004 Sep; 143(2):251-6. doi:
10.1038/sj.bjp.0705924. [PMID: 15289293] - J Szolcsányi, Z Sándor, G Petho, A Varga, K Bölcskei, R Almási, Z Riedl, G Hajos, G Czéh. Direct evidence for activation and desensitization of the capsaicin receptor by N-oleoyldopamine on TRPV1-transfected cell, line in gene deleted mice and in the rat.
Neuroscience letters.
2004 May; 361(1-3):155-8. doi:
10.1016/j.neulet.2003.12.025. [PMID: 15135917] - Constance J Chu, Susan M Huang, Luciano De Petrocellis, Tiziana Bisogno, Scott A Ewing, Jeffrey D Miller, Robert E Zipkin, Nives Daddario, Giovanni Appendino, Vincenzo Di Marzo, J Michael Walker. N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia.
The Journal of biological chemistry.
2003 Apr; 278(16):13633-9. doi:
10.1074/jbc.m211231200. [PMID: 12569099]