n-arachidonylethanolamine (BioDeep_00000181244)
human metabolite blood metabolite
代谢物信息卡片
化学式: C22H39NO (333.3031)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 67.44%
分子结构信息
SMILES: CCCCCC=CCC=CCC=CCC=CCCCCNCCO
InChI: InChI=1S/C22H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23-21-22-24/h6-7,9-10,12-13,15-16,23-24H,2-5,8,11,14,17-22H2,1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Andrea Dlugos, Emma Childs, Kara L Stuhr, Cecilia J Hillard, Harriet de Wit. Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2012 Oct; 37(11):2416-27. doi:
10.1038/npp.2012.100. [PMID: 22763622] - W S Vanessa Ho, Matthew N Hill, Gregory E Miller, Boris B Gorzalka, Cecilia J Hillard. Serum contents of endocannabinoids are correlated with blood pressure in depressed women.
Lipids in health and disease.
2012 Feb; 11(?):32. doi:
10.1186/1476-511x-11-32. [PMID: 22373123] - Maxwell A Ruby, Daniel K Nomura, Carolyn S S Hudak, Anne Barber, John E Casida, Ronald M Krauss. Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes.
PloS one.
2011; 6(11):e26415. doi:
10.1371/journal.pone.0026415. [PMID: 22073164] - Linda K Vaughn, Gerene Denning, Kara L Stuhr, Harriet de Wit, Matthew N Hill, Cecilia J Hillard. Endocannabinoid signalling: has it got rhythm?.
British journal of pharmacology.
2010 Jun; 160(3):530-43. doi:
10.1111/j.1476-5381.2010.00790.x. [PMID: 20590563] - Jack C Sipe, T Michael Scott, Sarah Murray, Olivier Harismendy, Gabriel M Simon, Benjamin F Cravatt, Jill Waalen. Biomarkers of endocannabinoid system activation in severe obesity.
PloS one.
2010 Jan; 5(1):e8792. doi:
10.1371/journal.pone.0008792. [PMID: 20098695] - Yi Zhang, Gabriele E Sonnenberg, Tesfaye Mersha Baye, Jack Littrell, Jennifer Gunnell, Ann DeLaForest, Erin MacKinney, Cecilia J Hillard, Ahmed H Kissebah, Michael Olivier, Russell A Wilke. Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent.
Pharmacogenomics.
2009 Dec; 10(12):1929-39. doi:
10.2217/pgs.09.122. [PMID: 19958092] - Andreas Schmidt, Kay Brune, Burkhard Hinz. Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography.
Biomedical chromatography : BMC.
2006 Apr; 20(4):336-42. doi:
10.1002/bmc.568. [PMID: 16189813] - Robert Melamede. Cannabis and tobacco smoke are not equally carcinogenic.
Harm reduction journal.
2005 Oct; 2(?):21. doi:
10.1186/1477-7517-2-21. [PMID: 16232311] - Sachin Patel, Erica J Carrier, W-S Vanessa Ho, David J Rademacher, Sonya Cunningham, D Sudarshan Reddy, J R Falck, Benjamin F Cravatt, Cecilia J Hillard. The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity.
Journal of lipid research.
2005 Feb; 46(2):342-9. doi:
10.1194/jlr.m400377-jlr200. [PMID: 15576840] - Zoltán Járai, György Kúnos. [Cardiovascular effects of cannabinoids].
Orvosi hetilap.
2002 Jun; 143(26):1563-8. doi:
". [PMID: 12140859] - M I Nogueron, B Porgilsson, W E Schneider, C L Stucky, C J Hillard. Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons.
Journal of neurochemistry.
2001 Oct; 79(2):371-81. doi:
10.1046/j.1471-4159.2001.00567.x. [PMID: 11677265]
