N-(6-Aminohexyl)-1-Naphthalenesulfonamide (BioDeep_00000181196)
human metabolite blood metabolite
代谢物信息卡片
化学式: C16H22N2O2S (306.1401912)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 66.67%
分子结构信息
SMILES: C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)NCCCCCCN
InChI: InChI=1S/C16H22N2O2S/c17-12-5-1-2-6-13-18-21(19,20)16-11-7-9-14-8-3-4-10-15(14)16/h3-4,7-11,18H,1-2,5-6,12-13,17H2
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:92739
- PubChem: 4314
- HMDB: HMDB0255017
- ChEMBL: CHEMBL1188431
- chemspider: 4163
- CAS: 79458-81-4
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040
. [PMID: 33910017] - Min Lu, Yanyan Zhang, Shikun Tang, Jinbao Pan, Yongkun Yu, Jun Han, Yangyang Li, Xihua Du, Zhangjie Nan, Qingpeng Sun. AtCNGC2 is involved in jasmonic acid-induced calcium mobilization.
Journal of experimental botany.
2016 Feb; 67(3):809-19. doi:
10.1093/jxb/erv500
. [PMID: 26608645] - Christian Harteneck, Maik Gollasch. Pharmacological modulation of diacylglycerol-sensitive TRPC3/6/7 channels.
Current pharmaceutical biotechnology.
2011 Jan; 12(1):35-41. doi:
10.2174/138920111793937943
. [PMID: 20932261] - Bing Li, Hong-Tao Liu, Da-Ye Sun, Ren-Gang Zhou. Ca(2+) and calmodulin modulate DNA-binding activity of maize heat shock transcription factor in vitro.
Plant & cell physiology.
2004 May; 45(5):627-34. doi:
10.1093/pcp/pch074
. [PMID: 15169945] - S Suzuki, S Abe-Dohmae, T Fukutomi, S Ito, M Itoh, S Yokoyama. Enhancement of the cAMP-induced apolipoprotein-mediated cellular lipid release by calmodulin inhibitors W7 and W5 from RAW 264 mouse macrophage cell line cells.
Journal of cardiovascular pharmacology.
2000 Nov; 36(5):609-16. doi:
10.1097/00005344-200011000-00010
. [PMID: 11065221] - R M Bernal, R Tovar, J I Santos, M L Muñoz. Possible role of calmodulin in excystation of Giardia lamblia.
Parasitology research.
1998 Sep; 84(9):687-93. doi:
10.1007/s004360050471
. [PMID: 9766895] - P J Hartfield, J M Robinson. Arachidonic acid activates NADPH oxidase by a direct, calmodulin-regulated mechanism.
Prostaglandins & other lipid mediators.
1998 May; 56(1):1-6. doi:
10.1016/s0090-6980(98)00036-7
. [PMID: 9674016] - A Ito, M Yamada, T Sato, K Sanekata, H Sato, M Seiki, H Nagase, Y Mori. Calmodulin antagonists increase the expression of membrane-type-1 matrix metalloproteinase in human uterine cervical fibroblasts.
European journal of biochemistry.
1998 Jan; 251(1-2):353-8. doi:
10.1046/j.1432-1327.1998.2510353.x
. [PMID: 9492304] - C S Im, G L Matters, S I Beale. Calcium and calmodulin are involved in blue light induction of the gsa gene for an early chlorophyll biosynthetic step in Chlamydomonas.
The Plant cell.
1996 Dec; 8(12):2245-53. doi:
10.1105/tpc.8.12.2245
. [PMID: 8989881] - M Gröner, D Malchow. Calmodulin-antagonists inhibit vesicular Ca2+ uptake in Dictyostelium.
Cell calcium.
1996 Feb; 19(2):105-11. doi:
10.1016/s0143-4160(96)90079-2
. [PMID: 8689668] - K Ahmad, G E Bracho, D P Wolf, J S Tash. Regulation of human sperm motility and hyperactivation components by calcium, calmodulin, and protein phosphatases.
Archives of andrology.
1995 Nov; 35(3):187-208. doi:
10.3109/01485019508987871
. [PMID: 8585774] - L Proudfoot, J R Kusel, H V Smith, M W Kennedy. External stimuli and intracellular signalling in the modification of the nematode surface during transition to the mammalian host environment.
Parasitology.
1993 Dec; 107 ( Pt 5)(?):559-66. doi:
10.1017/s0031182000068141
. [PMID: 7507586] - S Wakusawa, K Takeda, K Miyamoto, H Hidaka. Increase of vinblastine accumulation by inhibitors of calmodulin-dependent cell functions in rat ascites hepatoma AH66 cells.
Anticancer research.
1992 Nov; 12(6B):2021-4. doi:
. [PMID: 1363514]
- G P Reddy, W C Reed, D H Deacon, P J Quesenberry. Growth factor-dependent proliferative stimulation of hematopoietic cells is associated with the modulation of cytoplasmic and nuclear 68-Kd calmodulin-binding protein.
Blood.
1992 Apr; 79(8):1946-55. doi:
NULL
. [PMID: 1562722] - K Tanabe, A Izumo, M Kato, A Miki, S Doi. Stage-dependent inhibition of Plasmodium falciparum by potent Ca2+ and calmodulin modulators.
The Journal of protozoology.
1989 Mar; 36(2):139-43. doi:
10.1111/j.1550-7408.1989.tb01060.x
. [PMID: 2657032] - K Takaichi, K Kurokawa. AVP-sensitive cAMP production is dependent on calmodulin in both MTAL and MCT.
The American journal of physiology.
1988 Nov; 255(5 Pt 2):F834-40. doi:
10.1152/ajprenal.1988.255.5.f834
. [PMID: 2847548] - K Sato, Y Mitsumoto, T Mohri. Possible participation of calmodulin in stimulation of leucine transport by concanavalin A in human lymphocytes.
Biochemical and biophysical research communications.
1988 Jun; 153(2):570-5. doi:
10.1016/s0006-291x(88)81133-1
. [PMID: 2454620] - H Shinyama, Y Matsumura, Y Sasaki, T Ichihara, S Morimoto. Renin release in anesthetized rats is enhanced by the calmodulin antagonist W-7.
Life sciences.
1987 Apr; 40(17):1687-94. doi:
10.1016/0024-3205(87)90018-x
. [PMID: 3550349] - N Hashimoto, T Maruyama, G Toda, Y Ikeda, Y Sugiyama, H Oka. Effects of calmodulin antagonists on secretion of bile and bile acid.
Gastroenterologia Japonica.
1987 Apr; 22(2):194-202. doi:
10.1007/bf02774217
. [PMID: 3596155] - J L Taft, M Shaw, J A Danks, R L Prince, R G Larkins. A role for calmodulin in renal production of 1,25-dihydroxyvitamin D3.
Endocrinology.
1986 Sep; 119(3):1131-6. doi:
10.1210/endo-119-3-1131
. [PMID: 3755394] - C D Wright, M D Hoffman. The protein kinase C inhibitors H-7 and H-9 fail to inhibit human neutrophil activation.
Biochemical and biophysical research communications.
1986 Mar; 135(3):749-55. doi:
10.1016/0006-291x(86)90992-7
. [PMID: 3008744] - Y Matsumura, N Miyawaki, Y Sasaki, S Morimoto. Inhibitory effects of norepinephrine, methoxamine and phenylephrine on renin release from rat kidney cortical slices.
The Journal of pharmacology and experimental therapeutics.
1985 Jun; 233(3):782-7. doi:
. [PMID: 2989497]
- T Nishimoto, K Ajiro, M Hirata, K Yamashita, M Sekiguchi. The induction of chromosome condensation in tsBN2, a temperature-sensitive mutant of BHK21, inhibited by the calmodulin antagonist, W-7.
Experimental cell research.
1985 Feb; 156(2):351-8. doi:
10.1016/0014-4827(85)90542-7
. [PMID: 3967683] - Y Matsumura, N Miyawaki, S Morimoto. Effects of W-7 and W-5 on renin release from rat kidney cortical slices.
Japanese journal of pharmacology.
1984 Oct; 36(2):268-71. doi:
10.1254/jjp.36.268
. [PMID: 6392655] - G Wolberg, T P Zimmerman. Effects of calmodulin antagonists on immune mouse lymphocytes.
Molecular pharmacology.
1984 Sep; 26(2):286-92. doi:
NULL
. [PMID: 6482875] - A Brock. Binding of digitoxin to human serum albumin: influence of ionic strength and ionic medium on the digitoxin-albumin complex formation.
Acta pharmacologica et toxicologica.
1975 Nov; 37(5):361-8. doi:
10.1111/j.1600-0773.1975.tb00854.x
. [PMID: 887] - I V Berezin, B M Kershengol'ts, N N Ugarova. [Microenvironment of enzymes as 1 of the factors determining enzyme stability. Stabilization of soluble and immobilized horseradish peroxidase].
Doklady Akademii nauk SSSR.
1975 Aug; 223(5):1256-9. doi:
NULL
. [PMID: 223]