N-(2-Hydroxyethyl)valine (BioDeep_00000181170)
human metabolite blood metabolite
代谢物信息卡片
化学式: C7H15NO3 (161.1052)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 93.75%
分子结构信息
SMILES: CC(C)C(C(=O)O)NCCO
InChI: InChI=1S/C7H15NO3/c1-5(2)6(7(10)11)8-3-4-9/h5-6,8-9H,3-4H2,1-2H3,(H,10,11)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Peter J Boogaard, Mathieu J P van Puijvelde, Jan H Urbanus. Biological monitoring to assess dermal exposure to ethylene oxide vapours during an incidental release.
Toxicology letters.
2014 Dec; 231(3):387-90. doi:
10.1016/j.toxlet.2014.05.014. [PMID: 24882394] - Gabriele Leng, Wolfgang Gries. Biomonitoring following a chemical incident with acrylonitrile and ethylene in 2008.
Toxicology letters.
2014 Dec; 231(3):360-4. doi:
10.1016/j.toxlet.2014.06.027. [PMID: 24960063] - Michael Bader, Wolfgang Will, Gunild Frey, Michael Nasterlack. Analysis of protein adducts as biomarkers of short-term exposure to ethylene oxide and results of follow-up biomonitoring.
Arhiv za higijenu rada i toksikologiju.
2012 Jun; 63(2):107-15. doi:
10.2478/10004-1254-63-2012-2211. [PMID: 22728792] - Roberto Bono, Marco Vincenti, Tiziana Schilirò, Deborah Traversi, Cristina Pignata, Enzo Scursatone, Giulia Dotti, Giorgio Gilli. Cotinine and N-(2-hydroxyethyl)valine as markers of passive exposure to tobacco smoke in children.
Journal of exposure analysis and environmental epidemiology.
2005 Jan; 15(1):66-73. doi:
10.1038/sj.jea.7500344. [PMID: 15026775] - Roberto Bono, Marco Vincenti, Umberto Saglia, Cristina Pignata, Roberto Russo, Giorgio Gilli. Tobacco smoke and formation of N-(2-hydroxyethyl)valine in human hemoglobin.
Archives of environmental health.
2002 Sep; 57(5):416-21. doi:
10.1080/00039890209601430. [PMID: 12641182] - Thomas Schettgen, Horst Christoph Broding, Jürgen Angerer, Hans Drexler. Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine.
Toxicology letters.
2002 Aug; 134(1-3):65-70. doi:
10.1016/s0378-4274(02)00164-9. [PMID: 12191862] - R Bono, M Vincenti, V Meineri, C Pignata, U Saglia, O Giachino, E Scursatone. Formation of N-(2-hydroxyethyl)valine due to exposure to ethylene oxide via tobacco smoke: A risk factor for onset of cancer.
Environmental research.
1999 Jul; 81(1):62-71. doi:
10.1006/enrs.1998.3937. [PMID: 10361027] - S Ovrebø, A Haugen, P B Farmer, D Anderson. Evaluation of biomarkers in plasma, blood, and urine samples from coke oven workers: significance of exposure to polycyclic aromatic hydrocarbons.
Occupational and environmental medicine.
1995 Nov; 52(11):750-6. doi:
10.1136/oem.52.11.750. [PMID: 8535495] - A D Tates, P J Boogaard, F Darroudi, A T Natarajan, M E Caubo, N J van Sittert. Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide.
Mutation research.
1995 Jun; 329(1):63-77. doi:
10.1016/0027-5107(95)00018-e. [PMID: 7770077] - V E Walker, T R Fennell, P B Upton, J P MacNeela, J A Swenberg. Molecular dosimetry of DNA and hemoglobin adducts in mice and rats exposed to ethylene oxide.
Environmental health perspectives.
1993 Mar; 99(?):11-7. doi:
10.1289/ehp.939911. [PMID: 8319608] - N J van Sittert, G D Beulink, E W van Vliet, H van der Waal. Monitoring occupational exposure to ethylene oxide by the determination of hemoglobin adducts.
Environmental health perspectives.
1993 Mar; 99(?):217-20. doi:
10.1289/ehp.9399217. [PMID: 8319627] - M Törnqvist, B Gustafsson, A Kautiainen, M Harms-Ringdahl, F Granath, L Ehrenberg. Unsaturated lipids and intestinal bacteria as sources of endogenous production of ethene and ethylene oxide.
Carcinogenesis.
1989 Jan; 10(1):39-41. doi:
10.1093/carcin/10.1.39. [PMID: 2910529] - E Bailey, A G Brooks, C T Dollery, P B Farmer, B J Passingham, M A Sleightholm, D W Yates. Hydroxyethylvaline adduct formation in haemoglobin as a biological monitor of cigarette smoke intake.
Archives of toxicology.
1988; 62(4):247-53. doi:
10.1007/bf00332482. [PMID: 3240090] - B J Passingham, P B Farmer, E Bailey, A G Brooks, D W Yates. 2-Hydroxyethylation of haemoglobin in man.
IARC scientific publications.
1988; ?(89):279-85. doi:
NULL. [PMID: 3198211]
