Mrz 2266 BS (BioDeep_00000181127)
human metabolite blood metabolite
代谢物信息卡片
化学式: C21H27NO2 (325.2042)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1C2CC3=C(C1(CCN2CC4=COC=C4)CC)C=C(C=C3)O
InChI: InChI=1S/C21H27NO2/c1-3-18-20-11-16-5-6-17(23)12-19(16)21(18,4-2)8-9-22(20)13-15-7-10-24-14-15/h5-7,10,12,14,18,20,23H,3-4,8-9,11,13H2,1-2H3
描述信息
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D009292 - Narcotic Antagonists
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- J Radulović, C Miljević, D Djergović, V Vujić, J Antić, S von Hörsten, B D Janković. Opioid receptor-mediated suppression of humoral immune response in vivo and in vitro: involvement of kappa opioid receptors.
Journal of neuroimmunology.
1995 Mar; 57(1-2):55-62. doi:
10.1016/0165-5728(94)00161-g. [PMID: 7706440] - A Ray, K Gulati, S Puri, P Sen. Role of kappa opioid receptors during stress responsiveness in rats.
Indian journal of experimental biology.
1993 Feb; 31(2):116-9. doi:
NULL. [PMID: 8388852] - G Leposavic, P O Cover, J C Buckingham. In vivo and in vitro studies on the opioidergic control of the secretion of gonadotrophin-releasing hormone and luteinizing hormone in sexually immature and adult male rats.
Neuroendocrinology.
1991 Jun; 53(6):579-88. doi:
10.1159/000125777. [PMID: 1652110] - J Y Summy-Long, L M Rosella-Dampman, G L McLemore, E Koehler. Kappa opiate receptors inhibit release of oxytocin from the magnocellular system during dehydration.
Neuroendocrinology.
1990 Apr; 51(4):376-84. doi:
10.1159/000125364. [PMID: 1971712] - K Yamada, M Nakano, S Yoshida. Inhibition of elevated arginine vasopressin secretion in response to osmotic stimulation and acute haemorrhage by U-62066E, a kappa-opioid receptor agonist.
British journal of pharmacology.
1990 Feb; 99(2):384-8. doi:
10.1111/j.1476-5381.1990.tb14713.x. [PMID: 2158377] - G Hamon, S Jouquey. Kappa agonists and vasopressin secretion.
Hormone research.
1990; 34(3-4):129-32. doi:
10.1159/000181811. [PMID: 1966562] - R K Xu, L Chen, H Li, S J Yang, X Y Huang. [Effects of kappa-opiate receptor antagonist MR-2266-BS on ACTH and prolactin release].
Sheng li xue bao : [Acta physiologica Sinica].
1989 Aug; 41(4):395-401. doi:
NULL. [PMID: 2557673] - P O Cover, J C Buckingham. Effects of selective opioid-receptor blockade on the hypothalamo-pituitary-adrenocortical responses to surgical trauma in the rat.
The Journal of endocrinology.
1989 May; 121(2):213-20. doi:
10.1677/joe.0.1210213. [PMID: 2547002] - L Bueno, M Gue, M J Fargeas, M Alvinerie, J L Junien, J Fioramonti. Vagally mediated inhibition of acoustic stress-induced cortisol release by orally administered kappa-opioid substances in dogs.
Endocrinology.
1989 Apr; 124(4):1788-93. doi:
10.1210/endo-124-4-1788. [PMID: 2924723] - K Yamada, M Imai, S Yoshida. Mechanism of diuretic action of U-62,066E, a kappa opioid receptor agonist.
European journal of pharmacology.
1989 Jan; 160(2):229-37. doi:
10.1016/0014-2999(89)90495-0. [PMID: 2547626] - M J Millan, A Członkowski, B Morris, C Stein, R Arendt, A Huber, V Höllt, A Herz. Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat.
Pain.
1988 Dec; 35(3):299-312. doi:
10.1016/0304-3959(88)90140-6. [PMID: 2906425] - J P Huidobro-Toro, S Parada. Kappa-opiates and urination: pharmacological evidence for an endogenous role of the kappa-opiate receptor in fluid and electrolyte balance.
European journal of pharmacology.
1984 Dec; 107(1):1-10. doi:
10.1016/0014-2999(84)90084-0. [PMID: 6098480] - M T Curtis, A M Lefer. Actions of opiate antagonists with selective receptor interactions in hemorrhagic shock.
Circulatory shock.
1983; 10(2):131-45. doi:
NULL. [PMID: 6301706]
